Mingming Xue's research while affiliated with China Agricultural University and other places
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Publications (12)
Compared to commercial breeds, Chinese local pig breeds have a greater ability to digest dietary fiber, which may be due to differences in intestinal microbiota. In this study, we fed Ding’an and DLY pigs high and low levels of dietary fiber, respectively, to investigate factors contributing to high dietary fiber adaption in Ding’an pigs. Twelve Di...
Ding’an (DA) pig, a prominent local breed in Hainan Province, exhibits notable advantages in coarse feeding tolerance and high-quality meat. To explore the potential genetic mechanism of coarse feeding tolerance in DA pigs, 60-day-old full sibling pairs of DA and DLY (Duroc-Landrace-Yorkshire) pigs were subjected to fed normal (5%) and high (10%) c...
Surgical castration can effectively avoid boar taint and improve pork quality by removing the synthesis of androstenone in the testis, thereby reducing its deposition in adipose tissue. The expression of genes involved in testis-derived hormone metabolism was altered following surgical castration, but the upstream regulatory factors and underlying...
Background
Exploring the hypoxia adaptation mechanism of Tibetan chicken is of great significance for revealing the survival law of Tibetan chicken and plateau animal husbandry production. To investigate the hypoxia adaptation of Tibetan chickens (TBCs), an integrative metabolomic-transcriptomic analysis of the liver on day 18 of embryonic developm...
Porcine body length is closely related to meat production, growth, and reproductive performance, thus playing a key role in the profitability of the pork industry. Cartilage development is critical to longitudinal elongation of individual vertebrae. This study isolated primary porcine vertebral chondrocytes (PVCs) to clarify the complex mechanisms...
Background
Shaziling pig is a well-known indigenous breed in China who has superior meat quality traits. However, the genetic mechanism and genomic evidence underlying meat quality characteristics of Shaziling pigs are still unclear. To explore and investigate the germplasm characteristics of Shaziling pigs, we totally analyzed 67 individual’s whol...
The screening of important candidate genes and the identification of genetic markers are important for molecular selection in the pig industry. The hematopoietically expressed homeobox (HHEX) gene plays an important role in embryonic development and organogenesis; however, the genetic variation and expression pattern of the porcine HHEX gene remain...
Background: Patterns of liver energy metabolism significantly differ from birth to adult in cattle undergoing change of rumen rumination. However, the genes involve in hepatic energy metabolism during bovine development and how regulate are still unclear.
Methods: In this study, 0-day-old newborn calves (0W) and 9-week-old weaned calves (9W) were u...
The aim of the present study was to explore the effects of dietary non-fibrous carbohydrate to neutral detergent fiber (NFC/NDF) ratios on rumen development of calves, and to investigate the mechanisms by integrating of lncRNA and mRNA profiling. Forty-five weaned Charolais hybrid calves [body weight = 94.38 ± 2.50 kg; age = 70 ± 2.69 d] were rando...
Cecotrophy is a special behaviour of rabbits. Eating soft faeces can improve feed efficiency and maintain gut flora in rabbits. In our previous study, we found that fasting from soft faeces significantly reduced growth rate and total cholesterol (TC) in New Zealand white rabbits (NZW rabbits), thereby resulting in lower values for body weight and f...
Rumen development in calves is affected by many factors, including dietary composition. MicroRNAs (miRNAs) are known to function in the development of the rumen in cattle, what is not known is how these miRNAs function in rumen development of calves fed with high and low ratios of non-fibrous carbohydrate (NFC)/neutral detergent fiber (NDF). A tota...
Background: Rabbit produce two kinds of feces: hard and soft feces, and they have a preference for consuming the latter. Although this habit of rabbits has been reported for many years, little is known on whether this behavior will impact growth performance and metabolism. The RNA-Seq technology is an effective means of analyzing transcript groups...
Citations
... The imbalanced activity between matrix anabolism and catabolism contributes to the observed changes in AC, other tissues, and fluids affected by OA (i.e., underlying bone, synovium, synovial fluid). Previous studies examined altered metabolism in various OA-associated tissues and their cell types, such as chondrocytes, to investigate disease-associated metabolic activity [7][8][9]. However, significant limitations of many studies are that they were performed in vitro and/or lacked healthy human controls, thereby hindering a complete understanding of the role metabolism plays in OA development. ...
... The marker genes identified in this study have an important impact and commercial value on pig meat quality improvement. By identifying key genes associated with adipose deposition, targeted genetic improvements can be achieved to improve adipose deposition levels and meat quality in pigs [72]. The discovery of these marker genes can not only help select pig breeds with moderate adipose deposition and excellent meat quality but can also speed up the breeding process and reduce breeding costs. ...
... A large number of DEGs that play essential roles in the regulation of bone development were identified. Key candidate genes were further identified through a combination of functional analysis with literature mining, including NKX3.2 [34][35][36][37][38][39][40], WLS [41][42][43], GREM1 [44][45][46], FGFR3 [47][48][49][50][51], HHEX [52][53][54], COL11A1 [55][56][57], and WNT16 [58,59]. These genes were mainly enriched in the BMP, FGF, Wnt, and Notch signaling pathways, suggesting that they are involved in the development of the pig vertebral column. ...
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... SLC16A1 is responsible for transporting monocarboxylic acid metabolites. SLC16A1 plays a crucial role in cancer metabolism (31). Lactate maintains glycolysis efficiency by regulating the pH level in cells and interstitium and upregulating SLC16A1 expression. ...
... Transcriptomic analyses suggested that transforming growth factor-β might be another hormone mediating the growth of rumen epithelium from pre-weaned to post-weaned calves [131]. Similarly, integrated analysis of differentially expressed long non-coding RNAs and mRNAs revealed thyroid hormone as another candidate hormone that mediates rumen development in postnatal animals [132,133]. ...
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... Sin embargo, los cecotrofos, o heces blandas, son diferentes a las heces finales, o heces duras, ya que los cecotrofos son de color claro, se forman en el ciego y se agrupan en racimos (Fig. 2). En contraste, las heces finales son oscuras y proceden del colon (Li et al. 2020). La formación de cecotrofos es una habilidad fisiológica para separar las partículas más finas del material en digestión para permitir su ingreso al ciego y dejar pasar las partículas más gruesas y toscas hacia el colon para la formación de las heces duras (Li et al. 2020). ...
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... Research on miRNAs in cattle has mainly focused on reproduction and production traits, such as muscle, adipose tissue, mammary glands and milk 21,26 . Recent studies have also investigated miRNAs expression in the rumen epithelium, but to the best of our knowledge, miRNAs have never been reported before in the rumen fluid [27][28][29] . ...
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