R.M. Painuli's research while affiliated with Hemwati Nandan Bahuguna Garhwal University and other places
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Publications (17)
Terminalia chebula is one of the traditional medicines used in the treatment of many diseases. In the present work, different concentrations of various organic and aqueous extracts (solvent-free) of T. chebula were tested on fibroblast (L929) and keratinocytes cells to evaluate its biocompatible concentration by using MTT and live-dead viability/cy...
In the present investigation, an attempt has been made to explore the traditional knowledge on herbal medicines used as a remedy for skin disorders by the Gujjar tribe of Sub-Himalayan tract, Uttarakhand. The purpose of this study is to assess traditional knowledge on medicinal plants which forms a baseline data for future pharmacological and phyto...
Ethnopharmacological relevance:
Although many plants are claimed to possess anticonvulsant/antiepileptic (AC/AE) properties, but there is very little information available about plants used by various ethnic communities in different parts of India to treat epilepsy, one of the most common disorders of central nervous system (CNS); this communicati...
Ethnopharmacological relevance:
Inspite of tremendous advances made in allopathic medical practices, herbs still play an important role in the management of various liver diseases. A large number of plants and formulations have been claimed to have hepatoprotective activity. Jaundice is a symptom, indicative of the malfunctioning of the liver. Thi...
The present study was conducted on the Van Gujjar tribe inhabiting a sub-Himalayan tract in the North Western Himalayas of Uttarakhand State, India. The Van Gujjars have been practicing transmigration over hundreds of years. They migrate each year with their households and livestock between summer and winter pastures. A few years ago with the annou...
The medicinal plants are laden with numerous effective antibacterial, antioxidants, anticancer agents which provide an alternative means of therapy to various infections caused by drug resistant bacteria, oxidative stress due to over-production of free radicals and leading to dreadful diseases like cancer and other physiological disorders. This stu...
In the present investigation an attempt has been made to explore traditional medicinal knowledge of plant spe-cies used against rheumatism by the Bhoxa tribe of district Dehradun. An ethnobotanical survey was carried out among the tribal people in all seasons to collect the relevant information about the medicinal uses of wild plants. Frequent fiel...
The oxidation stress is known to be a reason for various tissue degeneration and plays a role in premature aging. In wake of this, there is need to explore a natural antioxidant which can help body maintain a balance between inbuilt oxidation stress and detoxifying reactions. We present the antioxidant power of various extracts of Phyllanthus embli...
The present study highlights the traditional knowledge of Tharu tribe related with the use of plants as ethnomedicine. Extensive field trips were conducted in order to collect the ethnobotanical information. Questionnaire was made to gather data for local name, part used, disease treated, mode of administration and methods of preparation. The prese...
The Shiwalik Himalaya of Uttarakhand is rich in its floristic composition. It also represents varied population of forest dwellers, locales, and tribal communities which play a vital role in social, cultural, historical, economic and in-dustrial development of any country and in maintaining its ecological balance. Traditionally the folk people and...
In recent years, multiple drug resistance has been developed due to indiscriminate use of existing drugs in the treatment of infectious diseases. The major thrust is to establish alternative antimicrobial agent in order to treat microbial infections with less or no toxicity and less or negligible side effects. The herbal medicines have shown potent...
Throughout the globe, the traditional knowledge system has gained prime importance in context with conservation, sustainable development, and search for new utilization patterns of plant resources. In this context, the ethnomedicinal plants and the traditional healthcare system prevalent amongst the aboriginal and the rural population of various so...
The present paper highlights the indigenous knowledge on the ethnoveterinary medicinal plants used by the Gujjar community of Sub-Himalayan tracts in Garhwal Himalaya. This tribe is a nomadic one, lives with their livestock's in the forests, roaming from one place to other in different habitats. Their herds of livestock constituted a substantive ro...
Citations
... Previous GC-MS studies of the methanolic leaf extract of E. alba using helium gas as a carrier gas identified eight bioactive compounds [100] and seven bioactive compounds [98], as listed in Table 4, and these two studies reported the same bioactive compounds including c-sitosterol, oleic acid, eicosyl ester, 10-octadecenoic acid, and methyl ester. Furthermore, Chuahan and co-workers studied GC-MS analysis of ethyl acetate, methanol, and water extracts of the aerial part of the plant and reported that the extracts contained various bioactive substances, including glycine, hydrazine carboxyamide, garbamic acid, naphthoquinone, and other substances [99]. ...
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... The Sterile Petri Plate containing MHA medium were cultured with fresh bacterial colonies by using a sterile cotton swab, and wells were made in the agar plates by using a sterile well borer. The wells were loaded with different concentrations of extracts 0.5mg/100µl and 1mg/ 100µl (ethyl acetate, methanol, and aqueous) of Boerhaavia diffusa (roots and leaves) to check the antimicrobial activity of the extracts [7,8,9]. To produce concentrations of 0.5mg/100µl and 1mg/ 100µl, the extracts were diluted in DMSO (dimethylsulphoxide). Colistin (0.5mg/100µl and 1mg/100µl) was utilized as a positive control, whereas DMSO was employed as a negative control. ...
... Several researchers have stated C. baccharoides as a poisonous plant due to which, it was popular as 'Vispatra' (Gaur 1999;Sharma et al. 2011). However, Sharma et al. (2011) andPanwar et al. (2018) have reported the medicinal properties of its roots. ...
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... This can be achieved by promoting Field and seed gene banks in botanic gardens, scientific institutions, and forest nurseries where a population and diversity of endangered orchids can be maintained under technical supervision. Residents and forest dwellers have knowledge on how to use and conserve such species that have been passed down from generation to generation, so it is critical to use this expertise for effective assessment and conservation Sharma et al., 2011). Also encouraging In-vitro propagation of plants where facilities are available possible from seed, usually in aseptic conditions. ...
... Fibroblasts secrete collagen and affect the remodeling of granulation tissue into mature dermis [31]. Since the fibroblasts are the major targets in therapeutic drug design, bioactive compounds that can stimulate the proliferation of fibroblasts may be able to stimulate the healing process, as in the case of our present study [49]. MTT (3-[4-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide) assay, applied in this study, functions in multiple ways, and we set out to determine the active extracts and their optimal concentrations that can influence the metabolic activity of cells as well as measure the cell proliferation rate [50]. ...
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... Similarly, unripe fruit is used in abscess curing, whereas the fruit pulp is beneficial for urinogenital disorders, intestinal disorders, and other indigestion-related problems [8]. The mixture of powdered fruit and mustard oil is used in India to cure burn wounds [9]. Due to the antiseptic and astringent properties of the plant's flower, it is used in epilepsy and wound healing [10]. ...
... The plant species most preferred for treatment of both these diseases where Holarrhena pubescens Wall. and Helicteres isora L. Bhoxa community of Dehradun district, Uttarakhand, also prefers the same plant species as reported by Gairola et al. (2013) [15] . Other prevalent GI disorders were general digestive problems, loss of appetite and vomiting, followed by various other disorders given in Table-2. ...
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... Compared to the modern medicinal system, the plants used in the traditional system are cost-effective, easily available, have no side effects, and are highly safe. The traditional medicinal knowledge is passed down verbally from generation to generation without any written script, and due to rapid changes in socio-economy, technologies, modernization, and environment, the traditional ethnomedicinal plants are dissipating [4,5]. Therefore, the knowledge of traditional ethnomedicinal plants needs to be documented and preserved properly. ...
... Traditional knowledge is profoundly linked with natural resources and constitutes an essential facet of ancient cultural groups. This knowledge grows in close inter-reliance with the surroundings covering immense and diverse scopes for information generation (Sharma et al. 2013). From many decades, aboriginal people are believed to survive or live primarily in remote and inaccessible areas where they used to sustain their livelihood directly from forests and agricultural lands. ...
... Proficient and adequate knowledge regarding the proper usage of ethnomedicinal plants by aboriginal people of the Himalayan region is very minute despite that some new attempts were made Sharma et al. 2011a;2012a;2013a;2013b;Dangwal & Lal, 2020;, to explore the ethnomedicinal plants. In India, sub-Himalaya is a peculiar region of Uttarakhand. ...
