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Evaluating the efficacy of an online depression screening tool in South Africa: A pilot study

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Background: A global increase of 16% in depression rates from 1990 to 2019 highlights the alarming situation in relation to increase in depression. Research has indicated that this rate is likely to increase as a result of the coronavirus disease 2019 (COVID-19) pandemic. In South Africa, the depression life-time prevalence rate is 9.47%. However, the lack of access to mental healthcare services leads to people not receiving much needed information and care. The growing accessibility to the Internet for South Africans offers a solution for the screening and access to self-help information for depression. The Center for Epidemiologic Studies Depression Scale (CESD)-R was adapted for online usage and a website, mddsa.co.za, was piloted in this regard. Aim: This study reports on the efficacy of the online adapted CESD-R for use in South Africa by reporting on the reliability and criterion validity as well as the user friendliness of the website and the appropriateness of the instant feedback provided. Setting: The study was conducted in South Africa during COVID lockdown level 1 and 2. Methods: This study followed a quantitative, cross-sectional research design. A convenience sample of 21 individuals, above the age of 18, with a depression diagnosis and 86 individuals with no mental health diagnosis participated in the study. Participants accessed the screening instrument online at the website. Results: Internal consistency reliability coefficients exceeded 0.80. T-test and sensitivity and specificity results attested to the accuracy of the tool. All items contributed well to the instrument, including the items that were culturally specific to South Africa. Feedback from participants indicated that the tool was easily comprehensible, the website was user friendly and the instant feedback provided was appropriate. Conclusion: The online adapted CESD-R evidenced excellent reliability and criterion validity and was able to accurately screen for depression amongst South Africans. The website and the tool have the potential to be utilised to increase access to a screening instrument for individuals who display symptoms of depression and to enhance the opportunity for individuals to practise self-help.
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South African Journal of Psychiatry
ISSN: (Online) 2078-6786, (Print) 1608-9685
Page 1 of 8 Original Research
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Author:
Tasneem Hassem1
Aliaon:
1Department of Psychology,
Faculty of Human and
Community Development,
University of the
Witwatersrand,
Johannesburg, South Africa
Corresponding author:
Tasneem Hassem,
thassem@yahoo.co.za
Dates:
Received: 25 Jan. 2021
Accepted: 06 Aug. 2021
Published: 28 Feb. 2022
How to cite this arcle:
Hassem T. Evaluang the
ecacy of an online
depression screening tool in
South Africa: A pilot study.
S Afr J Psychiat. 2022;28(0),
a1687. hps://doi.
org/10.4102/sajpsychiatry.
v28i0.1687
Copyright:
© 2022. The Authors.
Licensee: AOSIS. This work
is licensed under the
Creave Commons
Aribuon License.
Introducon
Depression is currently ranked as the 13th leading cause of global burden of Disability Adjusted
Life Years (DAYLS) in 2019,1 as a result of a 16% increase in the global prevalence rate from 1990
to 2019. The life-time prevalence rate of depression in South Africa is 9.47%.2 Research suggests
that depression rates are likely to increase as a result of the coronavirus disease 2019 (COVID-19)
pandemic.3,4 This can be attributed primarily to experiences of isolation as well as other dramatic
changes in social and occupational spheres during the pandemic.5
Research on depression in the South African context highlights unique symptoms experienced by
individuals diagnosed with depression such as feelings of loneliness, not feeling like oneself,
‘thinking too much’ as well as an increased emphasis placed on somatic symptoms experienced
and reported by individuals.6,7,10,11 These symptoms have not been included in the Diagnostic and
Statistical Manual diagnostic criteria for depression, which states an individual needs to display
at least one symptom of either being depressed or loss of interest of pleasure for more than two
weeks and an additional five to nine symptoms present nearly every day.12 In South Africa the
diagnosis and treatment of depression has been compromised for various reasons, such as, the
challenges experienced in accessing mental healthcare, lack of mental health resources, depression
terminology is often not available in all South African languages to describe the diagnosis, the
Background: A global increase of 16% in depression rates from 1990 to 2019 highlights the
alarming situation in relation to increase in depression. Research has indicated that this rate is
likely to increase as a result of the coronavirus disease 2019 (COVID-19) pandemic. In South
Africa, the depression life-time prevalence rate is 9.47%. However, the lack of access to mental
healthcare services leads to people not receiving much needed information and care. The growing
accessibility to the Internet for South Africans offers a solution for the screening and access to
self-help information for depression. The Center for Epidemiologic Studies Depression Scale
(CESD)-R was adapted for online usage and a website, mddsa.co.za, was piloted in this regard.
Aim: This study reports on the efficacy of the online adapted CESD-R for use in South Africa
by reporting on the reliability and criterion validity as well as the user friendliness of the
website and the appropriateness of the instant feedback provided.
Setting: The study was conducted in South Africa during COVID lockdown level 1 and 2.
Methods: This study followed a quantitative, cross-sectional research design. A convenience
sample of 21 individuals, above the age of 18, with a depression diagnosis and 86 individuals
with no mental health diagnosis participated in the study. Participants accessed the screening
instrument online at the website.
Results: Internal consistency reliability coefficients exceeded 0.80. T-test and sensitivity and
specificity results attested to the accuracy of the tool. All items contributed well to the
instrument, including the items that were culturally specific to South Africa. Feedback from
participants indicated that the tool was easily comprehensible, the website was user friendly
and the instant feedback provided was appropriate.
Conclusion: The online adapted CESD-R evidenced excellent reliability and criterion validity
and was able to accurately screen for depression amongst South Africans. The website and the
tool have the potential to be utilised to increase access to a screening instrument for individuals
who display symptoms of depression and to enhance the opportunity for individuals to
practise self-help.
Keywords: criterion validity; depression; online screening; reliability; sensitivity; specificity.
Evaluang the ecacy of an online depression
screening tool in South Africa: A pilot study
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term depression is not understood in the same way across
cultures and the stigma associated with mental illnesses.6,7,8,9
An additional factor which compromises and often results in
the underdiagnosis of depression is the instrument used to
screen for depression amongst individuals.
Instruments which screen for depression are an additional
source of information to assist with diagnosis and are mostly
self-report instruments developed for Westernised countries,
thus posing a variety of challenges which impact on the
accuracy of these instruments. These instruments utilise
psychological jargon when assessing symptoms which is not
often understood by second language English speakers and
translations of these instruments into indigenous South
African languages often results in construed meaning of the
constructs measured. In addition, there is an emphasis placed
on assessing cognitive symptoms of depression and these
instruments do not account for the unique depression
symptoms identified in the South African context. Despite the
unique presentation of depression experienced by South
Africans, commonly used depression screening tools in the
South African context have not been adapted, however they
have been translated into various South African languages.13,14,15
The Center for Epidemiologic Studies Depression Scale
(CESD) is amongst one of the commonly utilised screening
instruments for individuals who have symptoms of depression
that has been translated into three South African languages
(Afrikaans, isiZulu and isiXhosa).13 The translated tool
evidenced reliability scores ranging between 0.69 and 0.89,
sensitivity and specificity ranging between 71.4% and 84.1%
and 72.6% – 95%, respectively. Positive predictive values
(PPV) ranged from 16.1% to 54.8%.13 The Centre for
Epidemiological Studies Depression – Revised scale (CESD-R)
administered on an electronic device (hand-held tablet)
evidenced an internal consistency reliability score of 0.95, a
sensitivity of 0.81 and specificity of 0.82 in a sample of HIV-
positive South African individuals.16 A pooled analysis of the
CESD has evidenced sensitivity and specificity of 87% (95%
confidence interval [CI] 0.82–0.91) and 70% (95% CI 0.65–0.75),
respectively, in a sample of general and primary care
population.17 Internationally, the paper versions of the CESD,
CESD-10 (10 items) and CESD-R evidenced reliability
coefficients ranging from 0.94 to 0.83,18,19,20,21,22 while a Cronbach
alpha of 0.82 was established for a shortened online version of
the CESD (7-items) amongst college students in Spain.23
On the basis of the unique symptom presentation of
depression, lack of mental health resources and the fact that
64.7% of South Africans have at least one member in their
household who has access to the Internet and only 8.4% of
individuals speak English as a home-language,24 [Author(s),
in press] (under review) adapted the CESD-R for online
usage within the South African context.25
The online depression screening tool is located on MDDSA.
co.za, as an open access resource. The website provides the
user with information regarding depression, the screening tool
as well as various contact details for individuals who are in
need of support. Once individuals take the test, they receive
instant feedback regarding their risk level (low, medium and
high) in terms of the depression symptoms they are
experiencing. The online adapted CESD-R demonstrates good
content validity25 and relevance, and a high internal consistent
reliability of 0.93 amongst postgraduate university students.
The efficacy of the tool for the general South African population
has not been determined. Thus, this study investigated the
reliability, criterion validity (sensitivity and specificity),
comprehensibility and user friendliness of the online adapted
CESD-R as well as the user friendliness of the website and
appropriateness of the instant feedback provided.
Methods
Study design
The study followed a non-experimental, quantitative, cross-
sectional research design, as participants completed a survey
via the website (MDDSA.co.za). A request made for
participation in the study was circulated by psychologists,
psychiatrists and general practitioners on various social media
platforms and in their consulting rooms. Data collection
commenced on 28 September 2020 and closed on 30 November
2020. It should be noted that data collection occurred during
the COVID lockdown Levels 1 and 2 in South Africa. During
lockdown Levels 1 and 2, all individuals were required to
wear face masks when in public places and all major sectors
were permitted to resume operations. Access to hospitals were
only permitted for obtaining medication and seeking
treatment, while adhering to strict health protocols.26
Study populaon
A non-probability convenience sample of 107 individuals
participated in the study.27 Table 1 highlights the sample
demographics. The majority of the sample (n = 86) were not
diagnosed with depression (No diagnosis [ND] sample),
whereas 21 individuals reported having received a formal
depression diagnosis (formally diagnosed [FD]). The majority
of the ND sample identified as being female (n = 60, 69.8%),
black people (n = 25, 37.9%), Christian (n = 40, 46.5%), and
spoke English as their home language (n = 50, 58.1%). The FD
were mainly female (n = 13, 61.9%), white people (n = 50.0%),
Christian (n = 42.9%) and spoke English (n = 17, 81%). The
ND participants had an age range of 19–70 years old (M = 35,
SD = 12.205), while the age range for the FD participants was
19–66 (M = 33.5, SD = 11.405).
In the ND sample, nine of the 11 official languages of South
Africa were selected as a home language, whereas only three
of the 11 languages were selected as the home language by
the FD sample. With regards to comprehension and reading
ability in English, majority of both the ND and FD samples
rated their ability as excellent. Majority of the ND and FD
samples reported not having been diagnosed with a physical
chronic condition (see Table 1).
The majority of the FD sample reported being diagnosed
with depression by a psychiatrist (n = 17, 81%) and stated
Page 3 of 8 Original Research
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that they had a depressive episode at least within the past
6 months of taking the survey (n = 12, 57.1%). In the FD
sample, 12 out of the 21 individuals were on medication to
treat their depression as is evident in Table 2.
Instruments
The survey consisted of a brief demographic questionnaire,
the adapted online CESD-R as well as several questions
assessing the comprehensibility and user friendliness of the
online adapted CESD-R, the user friendliness of the website
and the appropriateness of the instant feedback provided.
The brief demographic questionnaire requested information
regarding age, gender, population group, religious affiliation,
home language, health condition, depression diagnosis.
Participants who answered ‘Yes’ to being diagnosed with
depression had three follow-up questions relating to year of
diagnosis, who made the diagnosis as well as the occurrence
of the last depressive episode. Lastly, participants were asked
TABLE 1: Combined, No diagnosis and formally diagnosed sample demographics.
Demographics Variables Combined sample ND sample FD sample
Frequency Percentage Frequency Percentage Frequency Percentage
Gender Female 73 68.2 60 69.8 13 61.9
Male 34 31.8 26 30.2 8 38.1
RaceBlack 28 35 25 37.9 3 21.4
Coloured 8 10 6 9.1 2 14.3
Indian 15 18.8 14 21.2 1 7.1
White 25 31.3 18 27.3 7 50
Asian 2 2.5 1 1.5 1 7.1
Other 2 2.5 2 3 2 14.3
Religious aliaon Chrisanity 49 45.8 40 46.5 9 42.9
Hinduism 9 8.4 6 7.0 3 14.3
Islam 27 25.2 25 29.1 2 9.5
Judaism 6 5.6 5 5.8 1 4.8
No religious aliaon 11 10.3 7 8.1 4 19.0
Tradional African 3 2.8 3 3.5 - -
Other 2 1.9 - - 2 9.5
Home Language Afrikaans 5 4.7 5 5.8 - -
English 67 62.6 50 58.1 17 81.0
Sepedi 4 3.7 4 4.7 - -
Setswana 12 11.2 10 11.6 2 9.5
Sotho 4 3.7 2 2.3 2 9.5
Tshivenda 2 1.9 2 2.3 - -
Xitsonga 3 2.8 3 3.5 - -
isiXhosa 2 1.9 2 2.3 - -
isiZulu 4 3.7 4 4.7 - -
Non-South African 4 3.7 4 4.7 - -
Language prociency
(ability to speak and
undertake various
tasks)
Excellent 79 73.8 62 72.1 17 81.0
Good 25 23.4 21 24.4 4 19.0
Poor 2 1.9 2 2.3 - -
Very poor 1 0.9 1 1.2 - -
Language
comprehension
(ability to
understand)
Excellent 80 74.8 63 73.3 17 81.0
Good 26 24.3 22 25.6 4 19.0
Very poor 1 0.9 1 1.2 - -
Reading skills Excellent 83 77.6 66 76.7 17 81.0
Good 22 20.6 18 20.9 4 19.0
Poor 1 0.9 1 1.2 - -
Very poor 1 0.9 1 1.2 - -
Have you been
diagnosed with a
physical illness
No 84 78.5 71 17.4 13 61.9
Yes 23 21.5 15 82.6 8 38.1
Are you currently
taking medicaon
for your illness
No 79 73.8 70 81.4 9 42.9
Yes 28 26.2 16 18.6 12 57.1
Have you been
diagnosed with
depression previously
No 86 80.4 86 100 - -
Yes 21 19.6 - - 21 100
Note: N = 101, except where indicated otherwise, N = 80.
ND, No diagnosis; FD, formally diagnosed.
TABLE 2: Depression History of the depressed sample.
Depression history Variable Frequency Percentage
Who diagnosed you with
depression?
General Doctor 4 19
Psychiatrist 17 81
Last depression episode A year ago 9 42.9
During this month 4 19
In the past two months 7 33.3
In the past six months 1 4.8
Note: N = 21
Page 4 of 8 Original Research
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to rate ability in English from excellent to very poor with
regards to proficiency, comprehension and reading ability.
The online adapted CESD-R is grounded in the
Biopsychosocial-Spiritual (BPSS) model and consists of 19
items with a 4-point Likert type response format (0 = Not at
all, 1 = Some of the time, 2 = Most of the time and 3 = All the
time). It assesses symptoms over a two-month period. In
addition, the items are jargon free and can be easily
understood. Four items pertain specifically to the idioms of
distress experienced by the South African population,
namely, ‘I have been experiencing more body aches and
pains (e.g. headaches, neck pain or back pain)’, ‘I have been
thinking too much’, ‘I have been feeling alone’ and ‘I have
not felt like myself’. The tool is scored out of 57 and uses a
two-tier scoring system. Tier one looked at symptoms of
sadness and loss of interest, while Tier 2 focussed on appetite,
sleep, concentration, guilt, fatigue and movement based on
the symptom presentation outlined in the DSM-5.28 A cut-off
score of 20 and less placed individuals into the low-risk
category, a score ranging from 21 to 34 placed individuals in
a medium-risk category and a cut-off score of 35 and above
placed individuals in high-risk category. The tool displayed
good content validity in the South African context.24
Lastly, participants were asked to indicate via a Yes/No
response format on the user-friendliness of the tool and the
website, if the instructions provided were easily understood,
item appropriateness as well as to indicate if there were any
words or phrases they did not understand. After completion,
participants were presented with the results of the CESD-R
and asked to comment on the appropriateness of the feedback
provided.
Procedure
Participants received information about the study via
psychologists, psychiatrists, general practitioners and
through social media such as WhatsApp. Information about
the study included a link to the survey on the MDDSA.co.za
website. The survey took approximately 15 min to complete
and participants were provided with instant results based on
their item responses on the online adapted CESD-R.
Ethical consideraons
Approval to conduct the study was obtained from the Human
Research Ethics Committee – Medical (HRECM) of the
University of the Witwatersrand, reference number: M180402.
Participation in the study was completely voluntary and
anonymous. Participants were informed about the study via a
participant information sheet and free online and telephonic
counselling details were provided to participants in the event
of experiencing any form of distress.
Data analysis
Data was extracted from the website database and coded
for analysis. IBM Statistical Package for the Social Sciences
(SPSS) Statistics 27 and JASP was used to analyse the coded
data. Demographic variables as well as the six questions
regarding the tool and website were analysed using
frequencies and percentages. In order to determine
the internal consistency reliability a Cronbach’s alpha
coefficient and the McDonald’s Omega coefficient was
calculated. To determine the criterion validity (sensitivity,
specificity, PPV and negative predictive values [NPV]) of
the tool were calculated are per the recommendations made
by Trevethan.29 The Area Under the Receiver Operating
Characteristic Curve was used to determine the accuracy of
the tool. All the items were normally distributed as per
skewness calculations. In order to determine the
discriminatory power of the items amongst the ND and FD
samples, an independent samples t-test was utilised; and
where results were significant the Cohen’s d was calculated
to determine the effect size.
Results
Descripve stascs
Table 3 highlights the means scores obtained for both the ND
and FD samples. For all items, the mean scores for the FD
sample were larger than the mean scores for the ND sample;
however, all differences were statistically significant
(p < 0.05) with the exception of items 2, 3, 6 and 7 (p > 0.05).
Large effect sizes ranging between 0.906 and 1.021, was
evident for items 1, 5, 8, 9, 10, 11, 12 and 18, while moderate
effect sizes ranging between 0.785 and 0.888 was evident for
items 4, 13, 14, 15, 16, 17 and 19. Lastly, the mean total score
for the FD sample was significantly higher than the mean
total score for the ND sample (t105 = 4.22, p = 0.000;
Cohen’s d = 12.239).
Reliability of the adapted online Center for
Epidemiologic Studies Depression Scale-R
As is evident in Table 4, the online adapted CESD-R displays
an excellent internal consistency reliability with a
Cronbach’s alpha coefficient of 0.952 and McDonald’s
omega coefficient of 0.954 for the combined samples.30 The
Cronbach alpha for the FD sample was 0.934, while the
McDonald omega was 0.938. For the ND sample, the
Cronbach alpha coefficient was 0.948 and the McDonald
omega coefficient was 0.950. Table 4 also demonstrates the
effect on reliability if an item is excluded. There are no
significant increases or decreases to the reliability
coefficients if any of the items are excluded. Thus, each item
contributes well to the tool.
Validity of the adapted online Center for
Epidemiologic Studies Depression Scale-R
As shown in Table 5, the majority (n = 45, 52.37%) of
the group without depressive features scores ranked them
in the low-risk category in the ND sample, while in the
FD sample the majority of the participants score ranked
them in the high-risk category (n = 10, 47.6%). In order
to determine the sensitivity, specificity, PPV and NPV,
Page 5 of 8 Original Research
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medium- and high-risk group were combined to represent
participants who display depressive features. In addition,
reporting being FD with depression constituted the ‘Gold
Standard’. Therefore, for the ND sample 41 participants
(47.7%) were classified as displaying depressive symptoms,
while in the FD sample 19 (90.5%) participants were
classified as displaying prominent depressive features
(Table 6).
With a cut-off score of 20, the tool produced a sensitivity of
90.48% and a specificity of 47.67%, while the positive
predictive value was 31.67% and negative predictive value
was 95.75%. When looking at the ROC curve, it is evident
that the test has a fair accuracy with AUC (area under the
curve) equal to 0.776 and the accuracy of the tool is
statistically significant at a 95% confidence interval
(p = 0.000; 0.6631–0.889) (see Figure 1).
TABLE 3: Descripve stascs and independent samples t-test.
Item Combined sampleND sampleFD sample§Cronbach
alpha if
item is
deleted
Independent samples t-test
Mean Standard
Deviaon
Mean Standard
Deviaon
Mean Standard
Deviaon
tP-value Cohen’s d
1. I have been experiencing more body aches and pains
(e.g. headache, neck pain or back pain)
1.26 0.94 1.14 0.88 1.76 1.00 0.953 2.83 0.006*** 0.906
2. I have been thinking too much 1.70 0,91 1.64 0.94 1.95 0.74 0.950 1.64 0.110 0.909
3. I have been feeling sad or down 1.14 0.77 1.08 0.77 1.38 0.74 0.950 1.61 0.110 0.765
4. I had trouble keeping my mind on what I was doing 1.07 0.84 0.92 0.76 1.71 0.90 0.950 4.16 0.000*** 0.785
5. My weight has changed without me trying (lost weight or gained
weight)
1.07 1.04 0.93 0.99 1.67 1.07 0.951 3.01 0.003*** 1.006
6. I felt like I have been moving too slowly 1.04 0.92 0.98 0.84 1.29 1.19 0.951 1.12 0.272 0.917
7. I could not make a decision about simple things 0.79 0.95 0.70 0.93 1.14 0.96 0.952 1.95 0.054 0.940
8. I could not get rid of this sad feeling 0.97 0.94 0.85 0.91 1.48 0.87 0.949 2.84 0.005*** 0.906
9. I have lost interest in my usual acvies 1.00 0.98 0.81 0.88 1.76 1.04 0.948 4.28 0.000*** 0.909
10. I felt that most things are my fault 1.16 1.05 1.03 1.35 1.00 1.11 0.949 2.54 0.013*** 1.021
11. I have not liked myself 0.93 1.02 2.15 0.71 0.92 0.93 0.950 4.91 0.000*** 0.921
12. My sleep has changed (having trouble sleeping or sleeping more
than usual)
1.35 1.06 2.63 1.16 0.99 1.00 0.950 3.86 0.000*** 0.993
13. I could not do things that I’ve always done 0.86 0.90 2.43 0.76 0.83 1.06 0.950 2.49 0.014*** 0.874
14. I have been feeling red 1.45 0.92 2.99 1.27 0.87 0.87 0.949 4.46 0.000*** 0.851
15. I could not focus on important things 0.98 0.89 2.69 0.83 0.77 1.07 0.949 3.90 0.004*** 0.836
16. My eang has changed (eang less than normal/more than
normal)
1.07 0.94 2.62 0.90 0.85 1.00 0.950 4.03 0.000*** 0.883
17. Nothing has made me happy 0.82 0.92 2.26 0.70 0.84 1.07 0.949 2.94 0.004*** 0.888
18. I have been feeling alone 1.09 1.01 2.52 0.99 1.01 0.93 0.950 2.21 0.029*** 0.996
19. I have not felt like myself 1.06 0.90 2.70 0.95 0.87 0.93 0.949 2.44 0.016*** 0.879
Total depression score 20.80 13.17 18.34 12.16 30.90 12.57 -4.22 0.000*** 12.239
Note: ***Signicant at α = 0.05, N = 107, N = 86, §N = 21.
ND, No diagnosis; FD, formally diagnosed.
TABLE 4: Reliability analyses.
Item Cronbach alpha if item is deleted McDonalds Omega if item deleted
I have been experiencing more body aches and pains (e.g. headache, neck pain or back pain) 0.953 0.954
I have been thinking too much 0.950 0.951
I have been feeling sad or down 0.950 0.951
I had trouble keeping my mind on what I was doing 0.950 0.951
My weight has changed without me trying (lost weight or gained weight) 0.951 0.952
I felt like I have been moving too slowly 0.951 0.952
I could not make a decision about simple things 0.952 0.953
I could not get rid of this sad feeling 0.949 0.950
I have lost interest in my usual acvies 0.948 0.950
I felt that most things are my fault 0.949 0.951
I have not liked myself 0.950 0.951
My sleep has changed (having trouble sleeping or sleeping more than usual) 0.950 0.952
I could not do things that I’ve always done 0.950 0.951
I have been feeling red 0.949 0.950
I could not focus on important things 0.949 0.950
My eang has changed (eang less than normal/more than normal) 0.950 0.951
Nothing has made me happy 0.949 0.951
I have been feeling alone 0.950 0.952
I have not felt like myself 0.949 0.950
Combined sample 0.952 0.954
FD sample 0.934 0.938
ND sample 0.948 0.950
ND, No diagnosis; FD, formally diagnosed.
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As evidenced in Table 7, the website and depression screening
tool were viewed as user friendly by the majority of participants
(n = 103, 98.1%). The majority of the participants reported that
the instructions of the tool were easily understood (n = 104,
99%). Participants noted that terminology used to define
symptoms were easy to understand (n = 101, 97.1%) and
reported that the items or phrases in the tool were appropriate
(n = 100, 96.2%). With regards to the instant feedback provided
only 90 participants responded, with majority (n = 86, 96%)
indicating the feedback provided was useful.
Discussion
This study set out to assess the reliability, criterion validity
(sensitivity and specificity) comprehensibility as well as the
user friendliness of the online adapted CESD-R tool. In
addition, the user friendliness of the website as well as the
appropriateness of the instant feedback provided was
assessed. Results indicate that the online adapted CESD-R is
reliable, valid, user friendly and comprehensible. In addition,
the website on which the tool is located is user friendly and
the instant feedback provided is appropriate.
The 19 items on the tool are each able to discriminate between
individuals who present with depressive features and
individuals who do not display prominent symptoms of
depression, as the FD sample obtained statistically higher
means on 15 (1, 4, 5, 8–19) out of the 19 items when compared to
the ND sample. Items that did not display a statistical difference
in mean scores between the FD and ND sample, assessed
concentration (3, 7), sadness (2) as well as movement (6).
The four items which constitute symptoms unique to
individuals who are diagnosed with depression in South
Africa, which are not included in the diagnostic manual used
for classifying and diagnosing depression can be deemed
appropriate. The appropriateness of these items (1, 18, 19) is
reflective in a statistically higher mean obtained by the FD
sample when compared to the ND sample. In addition, these
items all contribute to the overall reliability score of the tool
and removal of any of these items does not increase the
overall reliability score of the tool.
The online adapted CESD-R evidenced an excellent
reliability scores, which is higher than the lower and
equivalent upper range of the paper-based CESD-1013 and
equivalent to the CESD-R administered on a hand-held
tablet within the South African context.16 When compared to
the reliability scores established on the paper-based version
of the CESD, CESD-10 and the CESD-R, the adapted version
evidenced a higher reliability coefficient.18,19,20,21,22 Lastly,
the online adapted CESD-R displays a higher reliability
coefficient when compared to the online CESD administered
to a Spanish college sample23 and the online adapted CESD-R
administered to a South African postgraduate sample.
The online adapted CESD-R displayed a higher sensitivity
and a lower specificity score in relation to the paper-based
CESD-10 and CESD-R administered on a hand-held tablet
within the South African context.12 The higher sensitivity
score can be attributed to the easy-to-understand language,
the inclusion of the symptoms displayed by South Africans
FD with depression as well as the removal of positive affect
items which performed poorly on the paper-based CESD-
10.13 The lower specificity score can be attributed to the
timing of the study, where depression is viewed as a
psychological reaction to the COVID-19 pandemic,5 thus,
increasing depression symptoms experienced by the ND
sample. The low PPV and high NPV evidenced is in
accordance with that reported by Baron et al.13 However, the
PVV is lower and the NPV is higher than those reported by
Kagee et al.,16 which can be attributed to the higher prevalence
rate of depression amongst the sample recruited by Kagee
et al.16 The low PPV is a direct result of the relatively small
sample size of FD depressed individuals in the study.
As a result of the removal of psychological jargon from
the online adapted tool, it is evident that the instructions
TABLE 6 : Basis for deriving sensivity, specicity, posive and negave predicve
values.
Variable Result
True posive N = 19
False negave N = 2
False posive N = 41
True negave N = 45
TABLE 5: Depression symptom risk category for the combined, No diagnosis and FD samples.
Depression risk category Combined sample ND Sample FD sample
Frequency Percentage Frequency Percentage Frequency Percentage
Low risk 47 43.9 45 52.3 2 9.5
Medium risk 30 28 21 24.4 9 42.9
High risk 30 28 20 23.3 10 47.6
ND, No diagnosis; FD, formally diagnosed.
1.0
0.8
0.6
0.4
0.2
0.0
0.0 0.2 0.4
1 - Specificity
Sensivity
0.60.8 1.0
Reference lineSurvey total score
FIGURE 1: ROC Curve showing the AUC for the online adapted CESD-R.
Page 7 of 8 Original Research
hp://www.sajpsychiatry.org Open Access
as well as items can be easily understood by individuals
who are not first language English speakers. The user
friendliness of the tool and the website highlights the
potential the tool has in allowing individuals to assess
their symptoms in the comfort of their own homes and on
their own time, thus holding the potential to reduce the
stigma associated with depression within the community
settings. Lastly, the instant feedback provided to all risk
groups (low, medium, and high) was well received, thus
highlighting the appropriateness of the way feedback
is displayed.
Limitaons
The sample size and the time at which the study was
conducted are limitations in this study. As a result of the
COVID-19 pandemic and limited access to hospitals and
treatment facilities, the researcher was not able to obtain a
larger and more representative sample of individuals
diagnosed with depression. In addition, many individuals
with no history of depression may have experienced
symptoms of depression as a result of the effects of the
pandemic. As a result of the sample size, more sophisticated
statistical techniques such as item response theory analysis
and confirmatory factor analysis could not be performed.
Therefore, it is recommended that testing continue to
obtain a larger and more representative sample size.
Conclusion
The study provides evidence that the online adapted
CESD-R displays good reliability and validity while
accounting for the unique symptoms of depression
experienced by South Africans. As a result of the ease of
accessibility and user friendliness of the tool, the adapted
online CESD-R has the potential to be utilised in both public
and private healthcare facilities in South Africa as an
adjunct to the clinical observations that are usually done on
the clinical setting. Lastly, the instant feedback provided as
well as the information on self-help and contact details for
further assistance can be viewed as a step towards the
creation of awareness of the symptoms of distress that
might lead to a diagnosis of depression and it might assist
individuals to seek more formal modes of assessment and
treatment if necessary.
Acknowledgements
Compeng interests
The author has declared that she has no financial or personal
relationships that may have inappropriately influenced her
in writing this article.
Author’s contribuons
T.H. is the sole author and was responsible for the
conceptualisation, data collection and analysis as well as
write up for the article.
Funding informaon
This work is based on the research supported wholly or in
part by the National Research Foundation of South Africa
(Grant Number:112948).
Data availability
Data sharing is not applicable to this article, as no new data
were created or analysed in this study.
Disclaimer
The views and opinions expressed in this article are those of
the author and do not necessarily reflect the official policy or
position of any affiliated agency of the author.
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Within the context of screening tests, it is important to avoid misconceptions about sensitivity, specificity, and predictive values. In this article, therefore, foundations are first established concerning these metrics along with the first of several aspects of pliability that should be recognized in relation to those metrics. Clarification is then provided about the definitions of sensitivity, specificity, and predictive values and why researchers and clinicians can misunderstand and misrepresent them. Arguments are made that sensitivity and specificity should usually be applied only in the context of describing a screening test’s attributes relative to a reference standard; that predictive values are more appropriate and informative in actual screening contexts, but that sensitivity and specificity can be used for screening decisions about individual people if they are extremely high; that predictive values need not always be high and might be used to advantage by adjusting the sensitivity and specificity of screening tests; that, in screening contexts, researchers should provide information about all four metrics and how they were derived; and that, where necessary, consumers of health research should have the skills to interpret those metrics effectively for maximum benefit to clients and the healthcare system.
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Background The 10-item Centre for Epidemiological Studies Depression Scale (CES-D-10) is a depression screening tool that has been used in the South African National Income Dynamics Study (NIDS), a national household panel study. This screening tool has not yet been validated in South Africa. This study aimed to establish the reliability and validity of the CES-D-10 in Zulu, Xhosa and Afrikaans. The CES-D-10’s psychometric properties were also compared to the Patient Health Questionnaire (PHQ-9), a depression screening tool already validated in South Africa. Methods Stratified random samples of Xhosa, Afrikaans and Zulu-speaking participants aged 15 years or older (N = 944) were recruited from Cape Town Metro and Ethekwini districts. Face-to-face interviews included socio-demographic questions, the CES-D-10, Patient Health Questionnaire (PHQ-9), and WHO Disability Assessment Schedule 2.0 (WHODAS). Major depression was determined using the Mini International Neuropsychiatric Interview. All instruments were translated and back-translated to English. Construct validity was examined using exploratory factor analysis with varimax rotation. Receiver Operating Characteristics (ROC) curves were used to investigate the CES-D-10 and PHQ-9’s criterion validity, and compared using the DeLong method. Results Overall, 6.6, 18.0 and 6.9% of the Zulu, Afrikaans and Xhosa samples were diagnosed with depression, respectively. The CES-D-10 had acceptable internal consistency across samples (α = 0.69–0.89), and adequate concurrent validity, when compared to the PHQ-9 and WHODAS. The CES-D-10 area under the Receiver Operator Characteristic curve was good to excellent: 0.81 (95% CI 0.71–0.90) for Zulu, 0.93 (95% CI 0.90–0.96) for Afrikaans, and 0.94 (95% CI 0.89–0.99) for Xhosa. A cut-off of 12, 11 and 13 for Zulu, Afrikaans and Xhosa, respectively, generated the most balanced sensitivity, specificity and positive predictive value (Zulu: 71.4, 72.6% and 16.1%; Afrikaans: 84.6%, 84.0%, 53.7%; Xhosa: 81.0%, 95.0%, 54.8%). These were slightly higher than those generated for the PHQ-9. The CES-D-10 and PHQ-9 otherwise performed similarly across samples. Conclusions The CES-D-10 is a valid, reliable screening tool for depression in Zulu, Xhosa and coloured Afrikaans populations.
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