Laura OspinaHannover Medical School | MHH · Institute of Immunology
Laura Ospina
Dr. rer. nat. Infection Biology
About
8
Publications
607
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44
Citations
Introduction
Additional affiliations
August 2014 - September 2016
Position
- Research Assistant on the project: “Antigen-specific immunologic intervention for cardiovascular diseases: anti-atherogenic effect of chronic/subcutaneous administration of combined Vitamin D / Dexamethasone with an atheroantigen in dyslipidemic mice”.
January 2012 - July 2014
Position
- Research Trainee on the project: “Immune intervention for cardiovascular disease: Formulation of a tolerogenic therapy against atherosclerosis and its evaluation in a murine model”.
January 2011 - December 2011
Position
- Research Trainee on the project: “Evaluation of the protective effect of Leish-110f vaccine in a murine model of cutaneous leishmaniasis by L. (V) panamensis”.
Education
February 2011 - October 2014
February 2006 - December 2010
National University of Colombia
Field of study
- Molecular Biology, Cytogenetics, Industrial bioprocesses
Publications
Publications (8)
The adoptive transfer of virus-specific T cells (VSTs) represents a therapeutic option for viral infection treatment in immunocompromised patients. Before administration, ex vivo culture enables VST expansion. However, it is unclear how ex vivo expansion affects the circulation, homing, and intra-tissue migration of administered VSTs. We establishe...
Abstract Book
OP‐248
DOI: 10.1002/eji.202170200
One of the interventional strategies to reestablish the immune effector/regulatory balance, that is typically altered in chronic inflammatory diseases (CID), is the reinforcement of endogenous immunomodulatory pathways as the one triggered by interleukin (IL)-10. In a recent work, we demonstrated that the subcutaneous (sc) administration of an IL-1...
Signaling via interleukin-2 receptor (IL-2R) is a requisite for regulatory T (Treg) cell identity and function. However, it is not completely understood to what degree IL-2R signaling is required for Treg cell homeostasis, lineage stability and function in both resting and inflammatory conditions. Here, we characterized a spontaneous mutant mouse s...
The targeting of proinflammatory pathways has a prophylactic and therapeutic potential on atherosclerotic cardiovascular diseases (CVD). An alternative/complementary strategy is the promotion of endogenous atheroprotective mechanisms that are impaired during atherosclerosis progression, such as the activity of tolerogenic dendritic cells (tolDC) an...
http://www.frontiersin.org/Community/AbstractDetails.aspx?ABS_DOI=10.3389/conf.fimmu.2015.05.00094&eid=2531&sname=IMMUNOCOLOMBIA2015_-_11th_Congress_of_the_Latin_American_Association_of_Immunology_-_10o_Congreso_d
