Yoko Narasaki's research while affiliated with University of California, Irvine and other places

... Considering this, much recent scientific evidence seems to recommend plant-based diets for both primary and secondary prevention of CKD [49][50][51][52]. Regarding salt intake, extensive research has shown that salt restriction has great potential to slow the progression of kidney disease and mitigate serious complications of CKD, such as high blood pressure [40]. ...

... Observational studies in patients with thyroid dysfunction have also shown a link with CKD, 2 although it is not yet clear if the thyroid is responsible for renal failure. In the study by You et al., 5 the authors set out to investigate whether hypothyroidism and hyperthyroidism are associated with higher CKD incidence and progression. ...

... This rate is 2.5 times higher than that of patients without diabetes (1). In diabetes, fluctuations with hyperglycemia and hypoglycemia occur (2). Hemodialysis treatment can cause glycemic fluctuations due to decreased plasma glucose concentrations and insulin levels. ...

... However, it is crucial to supplement protein intake with high-quality protein to prevent proteinuria. 72,73 Patients with osteoporosis may require additional calcium and vitamin D supplementation. 13,74 Meanwhile, maintaining proper hydration is vital to avoid dehydration and fluid overload. ...

... cardiovascular disease, cancer, chronic obstructive pulmonary disease) has declined over the past two decades, a similar reduction in age-standardized deaths has not been observed for CKD. 13 Understanding genetic and environmental factors influencing kidney function in healthy and diseased conditions and the interaction between genetic susceptibility factors and the environment can provide important insights into renal physiology and pathophysiology. It can reveal previously unknown or unexpected mechanisms, and consequently, research of genetic and environmental factors associated with chronic kidney disease (CKD) has the potential to identify novel therapeutic or preventive targets. ...

... Specifically, the risk of reaching kidney failure has been estimated to be significantly higher among Black and Hispanic patients by 3.4 and 1.3 times, respectively [5]. In addition, Asian Americans and Pacific Islanders have been shown to present a higher risk of early stage kidney disease, while native Hawaiian individuals have been proposed to be at greater risk of severe kidney disease forms [6]. Racial discrimination may be associated with kidney disease progression through its potential effects on social determinants of health, such as access to education and healthcare, while it may exert biological impact by contributing to increased allostatic load and epigenetic changes that may be implicated in altered hormone metabolism, albuminuria and kidney function decline [7,8]. ...

... Later on, the patient developed clinical presentations of CLABSI and was put on ciprofloxacin however her blood culture turned out negative. A growing body of literature documented that dialysis as a result of kidney disease and electrolytes imbalance increases the risk of BSI [26,27]. A combination of electrolyte imbalance and BSI accelerates patient's condition towards confusion and death [28][29][30]. ...

... Due to complexity of food components, the bioavailability of minerals varies greatly depending on their food sources [22]. Current evidences indicated that in addition to the quantity, food sources and forms of minerals were also of great importance in clarifying their associations with the risks of chronic diseases [23,24]. ...

... However, reducing dietary phosphorus without exacerbating protein-energy wasting can be challenging (Gutiérrez and Wolf, 2010). Protein-energy wasting, in turn, is known to increase the risk of mortality (Brown-Tortorici et al., 2022). Therefore, phosphate binders appeared to be more feasible clinical therapeutic options for ESRD patients with hyperphosphatemia. ...

... Such a diet is based on fruits, vegetables, seeds, nuts, tea, cocoa, and whole-grain cereals [97]. Among plant-based foods, Brazil nuts seem to have important benefits in CKD, even in end-stage kidney disease patients, due to their contents of proteins, selenium, omega-3 fatty acids, and fibers [98,99] (Figure 1). ...