Yifei Lv's scientific contributions
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Citations
... For example, KKP1 peptide activated Nrf2 downstream factors such as HO-1, and inhibited NF-Kβ, TNF-α, and IL-1β related inflammatory pathways in rat hepatic stellate (HSC-T6) cell line [228]. Furthermore, recently reported bivalent KEAP1 inhibitor, was found to instantly activate Nrf2 resulting in the maintenance of redox homeostasis, as well as the resolution of acute inflammatory response in vivo [229]. These studies are crucial in broadening the available arsenal of Nrf2-modulating agents and understanding their distinct mechanisms of action, safety profiles, and therapeutic windows. ...