Xuan Yang's research while affiliated with ShenJing Hospital of China Medical University and other places
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Publications (2)
Background
Pancreatic cancer (PCa) is a fatal malignancy with poor prognosis, high recurrence and mortality. Substantial reports have suggested long non-coding RNAs (lncRNAs) are implicated in development of numerous malignant tumors, and PCa is included. However, the correlation between novel lncRNA mir-99a-let-7c cluster host gene (MIR99AHG) and...
Background:
Increasing reports have revealed that dysregulated expression of long non-coding RNAs (lncRNAs) is involved in pancreatic carcinoma progression. This study intends to explore the function and molecular mechanism of lncRNA HLA complex group 11 (HCG11) in pancreatic carcinoma.
Methods:
The expression profiles of HCG11 in pancreatic car...
Citations
... The lncRNA that we identified, MIR99AHG, was identified as a long non-coding RNA located on chromosome 21q21.1. Some studies found that down-regulation of MIR99AHG was associated with lung adenocarcinoma, colorectal cancer, pancreatic cancer and breast cancer [22,[29][30][31][32]. Meng et al found that MIR99AHG functioned as a miRNA sponge and negatively targeted miR-577. ...
... MiR-579-3p has established a crucial role in various human diseases. For example, miR-579-3p dysregulation is tightly linked to pancreatic carcinoma progression [37]. Deregulation of miR-579-3p can affect hypoxia-induced endothelial cell damage and microglial M1 polarization [38]. ...
