Shuguang Han's research while affiliated with University of Electronic Science and Technology of China and other places

Publications (19)

Article
Currently, the clinical application of hydroxyapatite (HA) coatings are limited due to the lack of anti-infection, osteoinductivity and poor mechanical properties. In the present study, the strontium-containing hydroxyapatite (SrHA)/graphene oxide (GO)/vancomycin (Va) nanocomposite coating with drug delivery and antibacterial activity was fabricate...
Article
Effective bone repair applications of titanium-based biometals must have excellent self-antibacterial properties and osteogenesis. Due to the special nano-geometric structure of titanium dioxide nanotubes (TN), the modified TN can confer various biological functions on the surface of titanium-based biometals. In this study, we used anodization, hyd...
Article
According to the clinician's experience, the main reason for the inefficiency of osseointegration between biometal and surrounding bone tissue is still caused by the biological inertness on the surface. Due to the osteogenic effects of its titanium dioxide nanotubes (TiO2) and strontium ions, strontium-containing TiO2 nanotube (STN) coatings have b...
Article
In the present work, a nanoscale porous surface was gradually prepared on Ti surface by two-step method of acid corrosion and NaOH–H2O2 mixing treatment. This led to the formation of a TiO2 coating at the surface of the underlying Ti substrate. Then, silver nanowires were deposited on the nanostructured surface by spin-coating technology. The nanow...
Article
Ti-based implant materials still face implant-related infections and poor osseointegration as two major clinical challenges; thus, high-quality implantation demands a strategy that can provide Ti-based implants with long-term antibacterial ability and high osteogenic activity. In this study, gallium was successfully loaded into polydopamine-functio...
Article
Full-text available
A multifaceted coating with favourable cytocompatibility, osteogenic activity and antibacterial properties would be of great significance and value due to its capability for improving osseointegration and alleviating prosthesis loosening. This study marks the first report on the coating of TiO 2 nanotubular (TNT) arrays with Sr-and-Si-substituted h...
Article
A recent advancement in bone therapies is the development of advanced implants from arrays of titania nanotubes, which are fabricated with self-ordering electrochemical anodization of a Ti substrate. We have fabricated a novel interface by coating an anodized Ti substrate with polydopamine. This interface is suitable for the efficient incorporation...
Article
Poor bio-corrosion resistance and undesirable incomplete osseointegration restrict the application of hydroxyapatite (HA) as an implant coating material. In this study, a novel F-and-La co-substituted hydroxyapatite (FLaHA) coating, which was reinforced with strontium titanate nanotubes (STNTs), was applied on Ti substrates using a combination meth...
Article
Full-text available
Background Poor mechanical properties, undesirable fast dissolution rate, and lack of antibacterial activity limit the application of hydroxyapatite (HA) as an implant coating material. To overcome these limitations, a hybrid coating of Ag⁺-substituted fluorhydroxyapatite and titania nanotube (TNT) was prepared. Methods The incorporation of silver...
Article
Orthopedic implants need to be coated with biomedical coatings that can facilitate osseointegration and mitigate bacterial biofilm formation. Using anodisation and electrodeposition techniques, we modified Ti implants with a double-layer coating made of TiO2 nanotubes (TNT) and hydroxyapatite that was codoped with silver and manganese (AgMnHA). The...
Article
The adhesion strength, antibacterial property, biocompatibility and corrosion resistance of implant coating materials remain challenging. In this study, a novel silver-doped hydroxyapatite/calcium silicate (AgHA/CS) layer was deposited on Ti modified with TiO2 nanotube (TN) through electrodeposition (ED) combined with anodisation. The TN under laye...
Article
Hydroxyapatite (HA)-coated implants are more susceptible to bacterial infection because their bioactive surface, which is favourable for osseointegration, could also become a reservoir for bacterial colonisation. To solve this problem, an electrodeposition method for preparing silver- and strontium-modified antibacterial HA layers onto TiO2 nanotub...
Article
The key property in the preparation of a biomaterial is to facilitate the regeneration and/or replacement of injured organs and tissues. To obtain such a biomaterial, strontium and manganese co-substituted hydroxyapatite (SrMnHA) ceramic coatings on commercially pure titanium (CP-Ti) were successfully prepared by cathodic electrodeposition method....
Article
This work elucidated the corrosion resistance and cytocompatibility of electroplated Zn- and Si-containing bioactive calcium silicate/zinc-doped hydroxyapatite (ZnHA/CS) ceramic coatings on commercially pure titanium (CP-Ti). The formation of ZnHA/CS coating was investigated through Fourier transform infrared spectroscopy, X-ray diffraction (XRD),...
Article
Hydroxyapatite (HAp) coatings doped with magnesium ion is an attractive method to improve the biocompatibility and biodegradability of HAp coatings. In this paper, we used electrochemical deposition to study the production of magnesium-doped HAp (MgHAp) coatings onto pure titanium with anodized titanium oxide (TiO2) nanotubes as intermediate layer....
Article
To improve coating corrosion resistance and bioactivity, strontium (Sr) and gelatin (GLT) were simultaneously incorporated in calcium phosphate (Ca-P) to form Sr-Ca-P/GLT composite coating on titanium (Ti) by electrodeposition. The surface morphology, chemical composition, phase identification, bond strength, corrosion resistance, and cytocompatibi...
Article
To improve the corrosion resistance and biocompatibility of biomedical titanium, strontium (Sr) and fluorine (F) were simultaneously incorporated in hydroxyapatite (HAp) to form SrFHAp coating on titanium (Ti) via electrodeposition. The microstructure, phase composition, corrosion resistance, and cytocompatibility of the films were studied. Results...
Article
This work elucidated the corrosion resistance and in vitro bioactivity of electroplated manganese-doped hydroxyapatite (MnHAp) film on NaOH-treated titanium (Ti). The NaOH treatment process was performed on Ti surface to enhance the adhesion of the MnHAp coating on Ti. Scanning electron microscopy images showed that the MnHAp coating had needle-lik...
Article
A novel method of electrolytic porous hydroxyapatite/calcium silicate (HA/CaSiO3) composite coating was conducted on pure titanium in a mixed solution of nano-SiO2, Ca(NO3)2 and NH4H2PO4. SEM observation showed that the composite layer was porous, thereby providing abundant sites for the osteoblast adhesion. XRD results showed that the composite co...

Citations

... Current research is focused on electrodeposition of HAp coatings, which has several advantages including easy setup, uniform coatings, deposition at low temperatures, and easy customization of morphology by adjusting electrolyte concentration and electrochemical potential and environmental protection. 50,51 The orthopaedic implants are of particular interest because they are ingested and remain in the body, making infections a major challenge. The accompanying infections frequently result in prosthetic device failure that necessitates the replacement of implants and typically result in chronic or recurring disease. ...
... The peaks corresponding to the surface oxygen of the ZnO lattice and adsorbed oxygen species were located at 530.04 and 531.55 in the O 1 s spectrum [37]. The high-resolution XPS spectra of Sr x Zn 1-x O samples in Fig. 2(B -D) show the Sr 3d and Sr-O occurring at 133.0 eV, which adds to the evidence of Sr doping [38]. At this energy, Sr 3d is the most intense signal that could be observed, which stands against the Zn 3S peak. ...
... (Durdu et al., 2021a;Gunputh et al., 2018;Mohammadpour;Behzadi;Moradi, 2015;Regonini et al., 2013;Yuan et al., 2021). Esse processo é amplamente utilizado na indústria para melhorar a resistência à corrosão, propriedades mecânicas e revestimentos de próteses com mudanças físicas e químicas sobre a superfície (Nakpan;Aeimbhu, 2021;Regonini et al., 2009;Zhang et al., 2020). ...
... Modifying surface coatings with AgNPs represents an attractive strategy to enhance the bioactivity and osseointegration of metallic implants used in orthopedics and orthodontics. The use of AgNPs in oxide and non-oxide ceramic coatings can minimize the infection susceptibility of metallic implants by modulating the coating's resistance to bacterial contamination and colonization, and exerting broad-spectrum antibacterial effects, while they maintain or improve their beneficial effects on osteogenic activity [477][478][479]. Furthermore, embedding AgNPs within polymer coatings represents an attractive strategy to generate antimicrobial surfaces for bone implants, with the additional osteogenic ability and boneforming potential [480][481][482]. ...
... A perovskite-structured oxide called strontium titanate (SrTiO 3 -STO) is known for its excellent piezoelectric, dielectric, and thermoelectric properties, as well as photocatalytic activity [35][36][37]. However, it has also been recognized in medicine, due to biocompatibility and bioactivity, as an osteogenesis promoter; furthermore, STO exhibits antibacterial activity, which makes it a valuable material for implants [38][39][40]. Si et al. showed that STO promotes the improvement of tribological properties, as well as the antibacterial activity when applied on titanium-based implants [41]. The potential of nanoparticle STO application in dental materials has still been limited to implant coatings, although it could offer advantages in other fields of medicine, as it has exceptional mechanical properties, such as high Young's modulus, compressive strength, and hardness [36,42]. ...
... Another study demonstrated that SrHA-Ag coatings, along with silicon co-doping, exhibited superior biological characteristics as compared to HA and HA-Ag coatings while maintaining similar anti-bacterial effects on HA-Ag coating. 71 The live/dead fluorescence staining on all the specimens exhibited their cytocompatible nature, and Ag is shown to have the least effect on the growth of osteoblast cells. Simultaneously, it can be observed that there is the highest number of live cells in the SrHA-Ag/Ti (ion-implanted) specimen. ...
... In recent years, development of water repellent and photoelectrochemical coatings have drawn a tremendous attention among the researchers towards the industrial applications such as self-cleaning [1,2], anti-fouling [3,4], anti-icing [5,6], corrosion resistance [7,8], bio-medical coatings [9,10], solar fuels production [11,12], etc Among the hydrophobic and photoelectrochemical coatings, anodic TiO 2 nanotubes (TNTs) on Ti foil has gained much attention over the past two decades owing to their superior properties such as photo-corrosion resistance [13], high chemical and thermal stabilities [14], non-toxicity [15], bio-compatibility [16], etc Xu, et al have first fabricated the super hydrophobic TiO 2 nanotubes coating which resulted in a contact angle of 157°. These super hydrophobic TNTs were fabricated by electrochemical anodization technique followed by dipping them in luric acid and subsequently dried at 60°C for 20 min [17]. ...
... No. assignment Infrared frequency (cm -1 ) Figure 3(b,e,d,c) prove the substitution of F À for OH À [42,44,45]. Also, stretching modes of OH À group of HA and Cu-FHA are present at 2318 cm À 1 and 2926 cm À 1 [35,42]. ...
... Silver dopant induces stresses within HA lattice; the theoretical boundary for Ag + doping is 20%. Moreover, the proper doping with silver ion is significantly below this limit 43,44 . It is widely believed that Ag-HA bioceramic composites may exhibit essential physicochemical features 45,46 . ...
... In conjunction with the recently discovered additively produced metallic scaffolds, substituted HAp coatings are expanding the therapeutic applications of metallic implants from their typical substitutive functions towards bone regeneration goals. The recent combination of substituted HAp and nanostructures has also opened up new prospects in coatings for orthopaedic applications [81][82][83]. ...