Seodhna M. Lynch's research while affiliated with Ulster University and other places
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Publications (5)
Background
Health organizations and countries around the world have found it difficult to control the spread of COVID-19. To minimize the future impact on the UK National Health Service and improve patient care, there is a pressing need to identify individuals who are at a higher risk of being hospitalized because of severe COVID-19. Early targeted...
BACKGROUND
Background - Health organisations and countries around the world have found it difficult to control the spread of the coronavirus disease 2019. To minimise the impact on the NHS and improve patient care, there is a drive for rapid tests capable of detecting individuals who are at high risk of contracting severe COVID-19. Early work focus...
Objective
The Covid Response Study (COVRES, NCT05548829) aims to carry out an integrated multi-omic analysis of factors contributing to host susceptibility to SARS-CoV-2 among a patient cohort of 1000 people from the geographically isolated island of Ireland.
Background
Health organisations and countries around the world have found it difficult to...
Severe COVID-19 is characterised by an overactive pro-inflammatory response of the immune system which is associated with new persistent symptoms. Differences in the persistence of symptoms, plasma inflammatory proteins and antibodies between hospitalised and non-hospitalised cases were investigated in the current study.
n=120 participants were rec...
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial morbidity and mortality worldwide, with particular risk for severe disease and mortality in the elderly population. SARS-CoV-2 infection is driven by a pathological hyperinflammat...
Citations
... By investigating the genetic, gene expression, and epigenetic profiles associated with COVID-19, it is possible to uncover essential information regarding the molecular signatures and regulatory processes involved in the progression and outcomes of the infection. Such comprehensive analyses have the potential to unveil novel biomarkers, therapeutic targets, and pathways that could enhance our understanding of COVID-19 pathophysiology and pave the way for more effective diagnostic and treatment strategies [71,72]. ...
... An advanced age has been recognized as a negative prognostic factor in patients with COVID-19. Hospitalized patients older than 65 years had higher rates of in-hospital complications and mortality than their younger counterpart [2,3]. ...
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