Ruth Axer-Siegel's research while affiliated with Tel Aviv University and other places
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Publications (111)
Purpose
The aim of this study was to evaluate whether the method of delivery has an effect on the incidence rate of recurrent rhegmatogenous retinal detachment in women who have been previously treated surgically for rhegmatogenous retinal detachment.
Methods
In this retrospective cohort study, data were collected from computerized files on Rabin...
Purpose
To compare intra- and postoperative complications in combined phacoemulsification and pars plana vitrectomy surgeries performed in patients with non-proliferative diabetic retinopathy (NPDR) vs. proliferative diabetic retinopathy (PDR).
Methods
Retrospective, case series of patients with diabetic retinopathy who underwent combined phacovit...
Background and objective:
To assess the foveal microvascular structure of children with retinopathy of prematurity (ROP) treated with diode laser photocoagulation using optical coherence tomography angiography (OCTA).
Patients and methods:
OCTA was performed at a tertiary medical center in 17 children (27 eyes) aged 4 to 16 years with a history...
Purpose:
To evaluate and correlate levels of various proteins involved in coagulation, inflammation and angiogenesis processes in the vitreous of patients with different vitreoretinal pathologies.
Methods:
Vitreous samples were collected from patients scheduled for pars plana vitrectomy for the treatment of rhegmatogenous retinal detachment (RRD...
Background and objective:
To determine whether subretinal fluid drainage (SRF) using perfluorocarbon (PFC) during rhegmatogenous retinal detachment (RRD) repair reduces postoperative metamorphopsia.
Patients and methods:
Consecutive patients after RRD were evaluated for best-corrected visual acuity (BCVA), funduscopy, and metamorphopsia using M-...
Purpose:
To model and analyse the ocular biometry of new-born infants.
Methods:
This work is based on previously published data of a cohort of 66 new-born infants aged 0-3 days. After exclusion of seven myopic subjects, the available retinoscopy, keratometry and ultrasound biometry data were analysed, along with calculated parameters such as len...
Purpose: This study aims to evaluate and correlate the levels of interleukin-6 (IL-6) and thrombin–antithrombin III complex (TAT) in the vitreous of patients with different vitreoretinal pathologies.
Methods: Vitreous samples were collected from 78 patients scheduled for pars plana vitrectomy at a tertiary medical center. Patients were divided by t...
Purpose: To study the efficacy and outcomes of short-term postoperative vitreoretinal tamponade with perfluorocarbon heavy liquid in patients with giant retinal tear.
Materials and Methods: The study group consisted of 13 consecutive patients (13 eyes) who presented with giant retinal tear at a tertiary medical center in 2011–2015 and were treated...
Background and objective:
Verteporfin photodynamic therapy (vPDT) plays a role in the treatment of chorioretinal conditions. The purpose of this study was to compare vPDT outcomes between cataractous and pseudophakic eyes.
Patients and methods:
In this prospective study of consecutive patients with choroidal neovascularization (CNV) secondary to...
Purpose:
To investigate the response to intravitreal ranibizumab after failure of intravitreal bevacizumab in patients with diabetic macular edema (DME).
Methods:
Demographics, visual acuity (VA), central macular thickness (CMT), and HbA1C were retrospectively collected from DME patients treated with second-line intravitreal ranibizumab at a ter...
Purpose: To investigate the response to intravitreal ranibizumab after failure of intravitreal bevacizumab in patients with diabetic macular edema (DME). Methods: Demographics, visual acuity (VA), central macular thickness (CMT), and HbAic were retrospectively collected from DME patients treated with second-line intravitreal ranibizumab at a tertia...
Purpose:
To evaluate the outcomes and complications of patients with diabetic tractional retinal detachment (TRD) treated with pars plana vitrectomy (PPV).
Patients and methods:
We retrospectively studied a case series of 24 eyes of 21 patients at a single tertiary, university-affiliated medical center. A review was carried out on patients who u...
The European Society of Cataract & Refractive Surgeons (ESCRS) study reported a decrease in endophthalmitis rates from 0.34 % to 0.08 % with the use of intracameral cefuroxime. The purpose of this study was to compare the endophthalmitis rates before and after the introduction of intracameral cefuroxime (ICC) routinely at the end of cataract surger...
Objective:
To evaluate long-term safety of intravitreal ranibizumab 0.5-mg injections in neovascular age-related macular degeneration (nAMD).
Design:
Twenty-four-month, open-label, multicenter, phase IV extension study.
Participants:
Two hundred thirty-four patients previously treated with ranibizumab for 12 months in the EXCITE/SUSTAIN study....
: To investigate the effect of intravitreal bevacizumab on the visual and anatomic outcome of patients with exudative age-related macular degeneration presenting with good visual acuity (VA).
: A file review was performed for all consecutive patients with newly diagnosed exudative age-related macular degeneration and initial VA of ≥20/40 treated in...
To investigate the visual and anatomical effects of intravitreal bevacizumab treatment of macular edema due to central retinal vein occlusion (CRVO).
Data were collected by medical chart review for 35 consecutive patients (35 eyes) with CRVO-induced macular edema treated with intravitreal bevacizumab in 2007-2010 and followed for at least 6 months....
To investigate the role of inflammation in age-related macular degeneration by measuring the levels of cytokines in the aqueous humour.
Samples of aqueous humour were collected from 34 patients with age-related macular degeneration and 16 age-matched control subjects undergoing cataract surgery. Age-related macular degeneration stage was determ...
There are 2 common alleles for Hp (Hp-1 and Hp-2) and 3 common Hp genotypes: Hp1-1, Hp2-1, and Hp2-2. The haptoglobin genotype may play a dual role in morbidities of diabetes: Hp1-1, protective and Hp2-2, provocative. This study investigated the possible association of haptoglobin genotypes with onset of retinopathy in Type 2 diabetes (DM2).
The sa...
To investigate the benefit of intravitreal bevacizumab as supplemental or primary treatment for retinopathy of prematurity.
The files of nine consecutive infants treated with intravitreal bevacizumab for bilateral severe posterior retinopathy of prematurity were reviewed.
Gestational age was 24 weeks to 27 weeks, and birth weight was 660 g to 1,131...
To demonstrate noninferiority of a quarterly treatment regimen to a monthly regimen of ranibizumab in patients with subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD).
A 12-month, multicenter, randomized, double-masked, active-controlled, phase IIIb study.
Patients with primary or recurrent subfoveal CN...
We report our experience with photodynamic therapy (PDT) in the treatment of choroidal neovascularization (CNV) in young adult patients. This was a retrospective study of young adults with CNV treated with PDT. Data collected included age, diagnosis, type and size of CNV, number of treatments, visual outcome, and side effects. Ten patients (11 eyes...
Pain is the main cause of patient distress/dissatisfaction after strabismus surgery. The aim of the study was to evaluate the effect of sub-Tenon's block with ropivacaine at the end of strabismus surgery on post-operative pain.
A prospective trial was conducted in 79 patients (age 1.0-65 years) scheduled for outpatient primary strabismus surgery wi...
To determine the precise age of suppression of the oculocephalic reflex in infants and its relationship to specific clinical characteristics.
The oculocephalic reflex was prospectively tested in 325 healthy full-term babies aged 1 to 32 weeks attending an orthopedic outpatient clinic. Two ophthalmologists raised the baby's head 30 degrees above hor...
The purpose of this study was to report our experience with intravitreal bevacizumab for inflammation-related choroidal neovascularization in two tertiary centers.
This study was a retrospective analysis of patients with choroidal neovascularization related to inflammatory diseases, treated with intravitreal bevacizumab injections (1.25 mg/0.05 mL)...
To evaluate the outcomes and complications associated with the repair of rhegmatogenous retinal detachment (RRD) using 25-gauge pars plana vitrectomy (PPV) with selective sclerotomy suturing.
Retrospective case series.
Analysis of consecutive 25-gauge pars plana vitrectomy cases performed for treating RRD was conducted. Reviewed parameters included...
To study the effect of intravitreal bevacizumab (Avastin) on the structure and growth of the young rabbit eye.
Twelve 6-week-old rabbits underwent intravitreal injection of bevacizumab (1.25 mg/0.05 ml) in one eye and no injection in the other (study group). Six additional rabbits served as controls. Slit lamp examination, fundus evaluation, and me...
To assess the effect of adjunctive intravitreal bevacizumab treatment on neovascular glaucoma (NVG).
The medical records of all consecutive patients with NVG treated with intravitreal bevacizumab at our center from May 2006 to February 2008 were reviewed. The data collected included background features, findings on full ophthalmologic examination (...
To evaluate the effect of combined intralesional and sub-Tenon's administration of corticosteroids for the treatment of refractory periocular and orbital capillary haemangioma in a retrospective, non-comparative study.
Seven infants with resistant periorbital and orbital capillary haemangioma who attended our tertiary centre from 2000 to 2005 were...
To evaluate the efficacy of topical lomefloxacin 0.3% versus chloramphenicol 0.2% with polymyxin B 2500 U/ml in the treatment of patients after strabismus surgery.
Seventy-nine consecutive patients who underwent strabismus surgery from April through October 2006 were randomized to receive topical lomefloxacin 0.3% (n = 45, 58 eyes) or chloramphenic...
To study the effect of intravitreal bevacizumab for the treatment of long-standing exudative age-related macular degeneration (AMD) and low visual acuity.
Forty-seven patients (48 eyes) aged 57 to 90 years with AMD for 5 months or more and visual acuity of 20/150 or less were treated with one or more injections of bevacizumab 1.25 mg/0.05 mL betwee...
To examine the anatomical and refractive outcomes of infrared diode laser photocoagulation (DLPC) for the treatment of threshold retinopathy of prematurity (ROP).
The charts of all consecutive premature neonates with ROP treated by DLPC at our tertiary center from December 1, 1996, to December 31, 2004, were reviewed.
The group included 100 neonate...
To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.
CRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.
Elevated CRP level...
Single nucleotide polymorphisms (SNPs) in the tightly linked LOC387715/ARMS2 and HTRA1 genes have been associated with age-related macular degeneration (AMD). We tested whether these SNPs are associated with AMD in Israeli populations, if they underlie variable phenotype and response to therapy in neovascular AMD (NVAMD), and if HTRA1 expression in...
The Tyr402His variant of complement factor H (CFH) is associated with age-related macular degeneration (AMD) in several populations. Our aim was to evaluate if this single nucleotide polymorphism (SNP) is associated with AMD in the Israeli population and see if it underlies heterogeneity in clinical manifestation and responses to photodynamic thera...
To evaluate the effects of in vitro fertilization (IVF) on early development of the eye in full-term healthy infants.
A case-control study was performed. The study sample included full-term infants born from March 1 to August 14, 2006, in the Neonatal Department of Helen Schneider Women's Hospital, Rabin Medical Center. Data were collected on sex,...
To compare the effectiveness of augmented superior oblique Z-tenotomy (SOZT) with fixed standard SOZT in canceling preoperative superior oblique overaction associated with A pattern anisotropia or V pattern in Brown's syndrome.
Sixteen consecutive patients with superior oblique overaction or Brown's syndrome were treated by removal of a triangular...
To evaluate the safety and efficacy of propofol sedation combined with sub-Tenon's anaesthesia for strabismus surgery in adults.
Thirty-two consecutive patients aged 31-85 years underwent strabismus surgery under general (n=16) or local (n=16) anaesthesia. In the local anaesthesia (study) group, sedation was induced with a loading dose of midazolam...
To determine the rate of agreement among five retina specialists in classifying various angiographic features of subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD), as evaluated on printed digital fluorescein angiogram (FA) frames, as well as determination of eligibility for photodynamic treatment (PDT)...
To evaluate the use of eye protection and frequency of eye splash events during intraocular injections as well as infection risk awareness among retina specialists and fellows in training.
In a prospective survey of practicing retina specialists and retina fellows, frequency of use and type of eye protection employed during intraocular injections,...
Subretinal hemorrhage is one of the most serious complications of exudative age-related macular degeneration (AMD). Treatment with vitreous surgery with or without plasminogen activator, fluid-gas exchange, or perfluorocarbon yields only a small improvement in visual acuity.
The files of 24 patients with submacular hemorrhage secondary to AMD who w...
To determine whether the incidence and severity of retinopathy of prematurity (ROP) differs between infants conceived naturally and those born after assisted conception, and to analyze the impact of singleton versus multiple gestation on ROP.
Comparative case series.
The study group consisted of 363 infants with a birth weight (BW) of < or =1500 g...
An abstract is unavailable. This article is available as HTML full text and PDF.
A cohort of hormonal signals affects the function of the eye in providing eyesight. From the early days of growth, endocrine mechanisms guide the young eye's development. Later on in life, hormonal interactions play an important role in maintaining proper vision and continue to affect the eyes in pregnancy, as well as in aging. The purpose of this...
To report the outcome of combined verteporfin photodynamic therapy (PDT) and intravitreal triamcinolone acetonide (IVTA) for the treatment of choroidal neovascularization (CNV) with serous pigment epithelium detachment (PED) due to age-related macular degeneration (AMD).
The files of all consecutive patients with CNV and serous PED who received PDT...
To compare the outcome of three vitrectomy techniques in the treatment of diabetic vitreous hemorrhage.
The study group included 38 patients (38 eyes) with diabetic vitreous hemorrhage. Three-port pars plana vitrectomy was used in 20 eyes, unimanual vitrectomy with indirect ophthalmoscopy in 10 eyes, and sutureless 25-gauge vitrectomy in 8 eyes. Ma...
Hyperglycemia, high blood pressure and hypercholesterolemia are risk factors for diabetic retinopathy and vision loss in diabetic patients.
To evaluate risk factors in patients treated for diabetic retinopathy in our hospital clinic and assess patients' awareness of the impact of glycemic control; and to compare the findings with those in patients...
To describe the first use of intravitreal voriconazole in a human eye for the treatment of Aspergillus endophthalmitis.
Interventional case report.
A 22-year-old woman receiving immunosuppressive agents 5 weeks after lung transplantation who presented with blurred vision and redness in the right eye.
Intravitreal injection of voriconazole (100 micr...
To evaluate the ocular dimensions in patients with primary growth hormone receptor insensitivity (Laron syndrome [LS]) and to study the effect of supplemental insulinlike growth factor I (IGF-I) on ocular growth.
Retrospective case series.
Twelve patients with LS, 8 untreated (LS group) and 4 treated (LS-T group) with supplemental IGF-I, and 30 hea...
To evaluate and compare the effects of peripheral retinal cryotherapy and diode laser photocoagulation on axial length, anterior chamber depth, and lens thickness in developing rabbit eyes.
26 eyes of 6 week old Abbit rabbits were randomly assigned to undergo laser photocoagulation or cryotherapy of the peripheral retina. Eight eyes of four untreat...
To compare the results of combined pars plana vitrectomy and cataract extraction with intraocular lens implantation by phacoemulsification versus manual extracapsular cataract extraction through a sclerocorneal tunnel.
Retrospective chart review of all patients who underwent combined pars plana vitrectomy with intraocular lens implantation and phac...
To investigate the role of inflammation in acute retinal artery occlusion (RAO).
Levels of interleukin (IL)-6, IL-8, and tumor necrosis factor alpha (TNF-alpha) were measured in serum (n = 14) and aqueous humor (AqH) (n = 8) samples from patients with RAO. Findings were compared with 24 age- and disease-matched patients, 10 healthy subjects (serum)...
We sought to evaluate the clinical course, complications, and visual outcome of pediatric uveitis.
Our sample included 38 consecutive children with uveitis treated between 1986 and 2002: 15 with idiopathic uveitis, 10 with Behcet disease, 9 with juvenile rheumatoid arthritis, 4 with other diagnoses. The last group was excluded from the analysis bec...
To compare the surgical and functional results of full tendon rectus muscle transposition to the medial rectus muscle augmented with posterior medial fixation sutures in patients with adduction deficiency (ADD) and Duane's syndrome type 2.
Retrospective nonconcurrent interventional comparative case series.
Twelve consecutive patients with ADD and D...
To evaluate the surgical and functional results of full horizontal tendon rectus muscle transposition to the superior rectus (SR) insertion, augmented by posterior fixation sutures, in patients with double-elevator palsy (DEP).
Retrospective nonconcurrent interventional comparative case series.
Fourteen consecutive patients with DEP.
Six patients t...
To evaluate the possible effect of in vitro fertilization (IVF) on early development of the eye in premature infants.
Biometric and keratometric values, intraocular pressure, and retinal vascular status were assessed in a cohort of 133 premature infants. These values were compared between premature infants conceived by IVF or naturally, and the rel...
To report a case of bilateral corneal graft dehiscence caused by blunt trauma.
Case report of bilateral simultaneous corneal graft dehiscence with expulsion of the lens and iris as a result of airbag-induced trauma.
Both corneal buttons were resutured, the prolapsed iris tissue was repositioned in the right eye, and anterior vitrectomy was performe...
To report our experience with intravitreal triamcinolone acetonide (IVTA) injections for the treatment of sight-threatening vitritis.
Interventional case series.
Three patients with acute severe exacerbations of noninfectious panuveitis and vitritis were treated with IVTA injections alone or as an adjunct to systemic immunosuppressive agents.
Rapid...
To evaluate the visual outcome of patients with myopic subfoveal choroidal neovascularization (CNV) given photodynamic therapy (PDT) in a clinical setting, and to identify potential relation between the visual outcome and the age at treatment.
Interventional case series.
Retrospective comparative study.
Outpatient ophthalmology clinic.
Twenty-nine...
To investigate the intraocular pressure (IOP) variations occurring after indirect diode laser photocoagulation for threshold retinopathy of prematurity.
Prospective, nonrandomized, comparative study.
A study group-21 consecutive premature babies (42 eyes) undergoing diode laser photocoagulation for retinopathy of prematurity-and control groups-32 p...
To compare refraction and keratometry readings between premature and term babies at 40 weeks' postconceptional age (PCA), and the possible effect of birth weight (BW) and gestational age (GA) on ocular parameters.
33 preterm babies hospitalised in the neonatal unit between January and March 2002 were matched with 33 term babies born within the same...
To study the visual and angiographic outcome of eyes with neovascular age-related macular degeneration associated with pigment epithelium detachment (PED) treated by photodynamic therapy.
Review of the medical charts and the fluorescein and indocyanine green angiograms of all consecutive patients with age-related macular degeneration associated wit...
To evaluate indocyanine green imaging of choroidal changes in pathologic myopia and to compare it with fluorescein angiography.
The angiograms of all consecutive patients with pathologic myopia photographed with confocal indocyanine green angiography using a scanning infrared laser or ophthalmoscope from March 1997 to December 1999 were reviewed.
T...
To evaluate the visual outcome of patients with subfoveal choroidal neovascularization due to age-related macular degeneration, who received photodynamic therapy (PTD) in a clinical setting and to identify potential predictive visual and angiographic factors.
Interventional case series.
The study included 74 patients with subfoveal choroidal neovas...
To assess the relationship between plasma homocysteine levels and exudative neovascular age-related macular degeneration (AMD).
Cross-sectional study.
A prospective comparative cross-sectional study was conducted in outpatient ophthalmology clinics in a university-affiliated medical institution. The cohort consisted of 59 patients (25 male, 34 fema...
To evaluate strabismus and binocular decompensation of exodeviation and their surgical treatment following corneal refractive surgery.
A retrospective study of a noncomparative case series was conducted. Seven patients whose strabismus worsened after photorefractive keratectomy or laser in-situ keratomileusis for correction of myopia underwent orth...
To evaluate the quantitative changes in botulinum toxin A (BTA) treatment required over time to achieve relief for 3 to 4 months in patients with essential blepharospasm (EBS) and idiopathic hemifacial spasm (IHFS).
Interventional case series.
In this retrospective longitudinal study in an institutional ophthalmologic outpatient clinic, data were r...
To identify the angiographic features of retinal choroidal anastomoses (RCAs) in patients with newly diagnosed occult choroidal neovascularization (CNV) in the setting of age-related macular degeneration (AMD) and to determine the sequence of flow between the RCA and the CNV.
Retrospective cross-sectional study.
The angiograms of 205 eyes of 153 co...
To evaluate alterations in the retinal vasculature overlying pigment epithelial detachments (PED) in exudative age-related macular degeneration (ARMD) using indocyanine green and fluorescein angiography.
Forty-one patients (41 eyes) with a clinical diagnosis of exudative ARMD with PED underwent simultaneous fluorescein and indocyanine green angiogr...
To evaluate the development of the tactile corneal reflex in healthy full-term babies.
Prospective longitudinal comparative case series.
One hundred and ninety-one babies aged 1 to 3 days examined in the nursery, and 200 babies aged 1 to 12 weeks examined in an orthopedic outpatient clinic.
The tactile corneal reflex was evaluated by three ophthalm...
To evaluate the role of transesophageal echocardiography (TEE) in detecting cardiac and thoracic aortic sources of retinal emboli.
Retrospective observational case series.
The study population consisted of 18 patients who were initially seen with retinal artery occlusion (7 central, 11 branch) and underwent TEE as part of the systemic evaluation.
A...
To study the efficacy of infrared diode laser for the treatment of posterior retinopathy of prematurity (ROP).
48 eyes of 25 premature babies (mean birth weight 779 (SD 127.7) g; mean gestational age 25.5 (SD 1.47) weeks) with threshold ROP in zone I and posterior zone II were treated by the indirect infrared (810 nm) diode laser. Confluent burns w...
To compare the efficacy of topical diclofenac sodium 0.1% versus dexamethasone 0.1% on the conjunctival healing process and on intraocular pressure (IOP) after strabismus surgery.
A randomized clinical trial.
Forty consecutive pediatric patients who underwent strabismus surgery.
The patients were assigned before surgery to receive topical diclofena...
To evaluate the analgesic effect of topical sodium diclofenac 0.1% during retinal laser photocoagulation.
87 patients, 45 with proliferative diabetic retinopathy treated with two sessions of panretinal photocoagulation (group A), and 42 patients with non-proliferative diabetic retinopathy who underwent grid treatment of the posterior pole (19 bilat...
To evaluate the efficacy of combined monocular resection and bilateral anterior transposition of the inferior oblique (IO) muscle for asymmetric double dissociated vertical deviation (DVD).
Nonrandomized, comparative clinical trial.
Twelve patients with asymmetric DVD and coexisting unequal IO overaction (IOOA).
Six consecutive patients underwent c...
To determine whether the use of supplemental prophylactic vancomycin in the irrigating solution during extracapsular lens extraction is associated with increased incidence of cystoid macular edema.
Prospective, randomized, double-masked clinical study.
Consecutive series of 118 patients 60 years of age or older undergoing cataract surgery.
The stud...
To describe the indocyanine green angiographic pattern of retinal pigment epithelium tears in the setting of age-related macular degeneration compared with the fluorescein angiographic features.
Twelve consecutive patients (12 eyes) with a retinal pigment epithelium tear underwent simultaneous indocyanine green angiography and fluorescein angiograp...
To investigate the topographic changes in the cornea after retinal and vitreous operations.
Observational prospective case series.
The study population included 46 patients after vitreoretinal surgery: 11 underwent pneumatic retinopexy, 10 underwent vitrectomy, and 25 underwent scleral buckling procedure.
The corneal topography was measured by vide...
To evaluate the displacement of retinal blood vessels during the natural course of epiretinal membrane (ERM) formation.
Consecutive observational case series.
Thirteen patients (13 eyes) diagnosed with unilateral idiopathic ERM and 10 normal fellow eyes of the same patients served as a control group and constituted the study group.
All eyes underwe...
To evaluate the efficacy of slanted recession of the lateral rectus (LR) muscle for exotropia (XT) with convergence weakness.
Predesigned, nonrandomized, comparative trial.
Twelve study patients and six control subjects with XT greater at near than at distance by > or =10 prism diopters (PD).
Twelve consecutive patients underwent slanted LR recessi...
To evaluate the intraocular pressure (IOP) variations which occur during and after strabismus surgery.
We measured the IOP in 34 eyes of 20 pediatric patients undergoing primary strabismus surgery under general anesthesia. Measurements were performed by the Tono-Pen (Mentor O&Q Inc. Norwell, MA) prior to surgery, immediately after suturing of the c...
To evaluate the potential of the retinal thickness analyser (RTA) as an objective tool for assessment and follow up of diabetic macular oedema.
A prototype of the RTA that operates on the principle of laser slit biomicroscopy was used. Retinal thickness was obtained in 41 eyes of 41 diabetic patients. The clinical diagnosis was cystoid macular oede...
To report angiographic findings of nonproliferative diabetic retinopathy patients by means of indocyanine green angiography.
Forty-two eyes (42 patients) with nonproliferative diabetic retinopathy were evaluated by indocyanine green angiography in addition to fluorescein angiography. Angiographic findings with the two imaging techniques were compar...
Pneumatic retinopexy is used as a primary procedure for the repair of retinal detachments caused by visible retinal tears. Its application for late-onset recurrent retinal detachments following previous pneumatic retinopexy or scleral buckling procedure has not been reported to date.
Pneumatic retinopexy was performed in 12 patients with recurrent...
Perfluorocarbon liquids are used as a vitreous substitute in the operative management of several ophthalmologic conditions. We examined the effects of residual perfluorocarbon droplets in the anterior chamber in patients after retinal detachment surgery.
The study group consisted of seven patients (seven eyes) aged 28-74 years in whom droplets of p...
To describe the course and risk factors for development and progression of retinopathy, we studied a cohort of 333 Israeli Jewish patients with Type 1 (insulin-dependent) diabetes mellitus. The median age at diagnosis was 9.5 (range 0.04-26.2) years and the median duration of follow-up was 14 (range 1.6-30) years. Evaluation of both retinae was per...
Radial keratotomy has recently been introduced for the correction of myopia. This procedure does not hinder progression of the pathophysiological changes in the myopic eye. We hereby describe a case of rhegmatogenous retinal detachment operation after radial keratotomy and present the operative considerations and refractive results.
Citations
... Moreover, simultaneous management of anterior and posterior segment pathologies can not only help patients achieve their best visual outcomes earlier but also reduce the number of surgeries and medical burdens. Several previous studies have been conducted, which demonstrated that the combined surgery was effective and gratifying, with optimal prognoses in patients with PDR and dense cataracts [21][22][23][24][25] . However, early lens extraction during PPV in patients with PDR and mild cataracts remains controversial. ...
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... Analyzing the general connection of D-dimer level with ophthalmic pathology in general, we can note the following correlations: the level of D-dimer is statistically significantly higher in patients with proliferative diabetic retinopathy than in patients with non-proliferative diabetic retinopathy [38,39]. Also, a statistically higher level of D-dimer was found in patients with leukemic retinopathy compared to the control group [40]. ...
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... Zhou et al. suggested that the presence of SRF is one of the independent predictors of metamorphopsia after RRD surgery [27], but they only used the Amsler grid to assess metamorphopsia qualitatively in their study, and no quantification of metamorphopsia is therefore available. Amir et al. investigated whether SRF drainage during RRD repair surgery would influence postoperative metamorphopsia [31]. ey found no association between SRF drainage and the M-scores. ...
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... biometry. The literature indeed shows relatively low correlations between refractive error 625 and axial length at birth, ranging between -0.188 and +0.03, 91,151,220 while the correlation be-626 tween corneal radius and axial length is relatively high at 0.575 -0.678. 22,220 In the months 627 and years that follow the active processes gain importance as indicated by the increased cor-628 relation between refractive error and axial length ( Table 2). ...
Reference: Emmetropization and non-myopic eye growth
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... VP was granted FDA approval in 2000 [10,11]. Since then, the potential of VP for the treatment of cancers, such as prostatic cancer and breast cancer, has been investigated [12]. ...
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... In a 1999 study, tissue plasminogen activator (tPA) and plasminogen activator inhibitor were shown to be elevated in the PDR vs. the non-diabetic vitreous [85]. Thrombin is known to stimulate IL-6 production [168]. Thrombin-antithrombin (TAT) complex and D-dimer levels are also elevated in the PDR vitreous [166,168]. ...
... PPV was the most commonly used surgical technique, ranging between 33.1% and 100% in 34 studies [10, 36-56, 58, 59, 61-70] (Appendix 2 in the Supplementary file). Additionally, 13 studies included only patients with RRD treated with PPV [45,46,49,50,53,55,56,59,61,64,[67][68][69]. Among the 20 studies that only used PPV to manage GRT-related RRD, 17 were associated with preoperative PVR [41, 42, 44-47, 49, 50, 53, 55, 56, 58, 59, 61, 62, 64, 66-69]. ...
... In agreement with (Ehrlich et al.) 5 study, which showed that CMT reduced from 435.95 ± 83.28 into 373.69 ± 44.39 m (P ¼ 0.01), which supported our findings. ...
... This differential utilization of aflibercept use may be because this drug was not approved for the treatment of DME until July 2014 instead of practitioner preference for this drug in DME treatment [24]. Conventionally, bevacizumab is used as initial therapy and is subsequently switched to ranibizumab or aflibercept for patients with refractory disease, which could also explain a differential choice in use of anti-VEGFs by the retina specialists [25]. These differences in use of aflibercept may also lead to differences in improvements in BCVA as some patients have been shown to have larger gains in vision with aflibercept than with bevacizumab or ranibizumab treatment, particularly patients with worse starting BCVA [10]. ...
... Overall, small gauge systems have dramatically improved attachment rates and visual acuity outcomes following vitrectomy for TRDs. Multiple retrospective studies assessing outcomes of vitrectomy for TRDs have demonstrated postoperative rates of visual acuity improvement in 75-90% of cases [11,[21][22][23]. Rates of complications of TRD repair vary greatly, with iatrogenic breaks reported in 5-45% of cases, secondary retinal detachments in 2.2-36%, vitreous hemorrhage in 9-54%, and reoperations in 7-21% of cases [11,21,[23][24][25][26][27]. ...
