Ruth Ann Parish's research while affiliated with Virginia Mason Medical Center and other places

... Poor quality radiographs, radiographs without a visible fracture, and records removed from consideration due to statistical and clinical irregularities (see below) were likewise removed from further consideration, resulting in a dataset of 1813 fracture time point records (927 displaced, 886 buckle) from 942 fractures (395 displaced, 547 buckle) occurring in various bones ( Figure 1) in individuals ranging in age from 0-19 year (Figure 2). The predominance of buckle fractures of the distal radius shown in Figure 1 is consistent with the typical mode and location of childhood fractures [1,3,4,20,42,45]. The distribution of patient ages in this convenience dataset is centered in mid-childhood ( Figure 2). ...

... There were few similar studies on the diagnosis of wrist fractures. Rivera et al. examined 116 patients and stated that clear deformity and point tenderness are the best predictors for detecting the possibility of fracture and it detects wrist fracture with a sensitivity and specificity of 81 and 82% (13). In the AWR derivation study, the researchers followed the recommended methodology to derive a decision rule. ...

... For many centuries Allium plants, and especially garlic, have been used as herbal medicines for treating a wide range of ailments, including hypertension, high blood cholesterol, and thrombosis (6). However, garlic can also produce adverse effects, such as cutaneous irritation, edema, and allergic contact dermatitis (7)(8)(9). In aqueous medium, allicin and other garlic derivatives are highly reactive compounds that can inhibit enzymes, modify nucleic acids, and alter membrane fluidity. ...

... Parish and Brownstein suggested giving pyridoxine in a gram for gram basis to children with a high suspicion of isoniazid overdose, owing to history or previous ingestion, without awaiting laboratory results [14]. "It can be safely given at a rate of 5 g per 3 minutes in a 50 mL volume. ...

... Garlic burn was first described by Parish et al. in 1987. [5] Garlic burns may develop in other circumstances as well, including occupational dermatitis and factitious dermatitis. ...

... Hyperglycemia commonly occurs in pediatric patients with moderate to severe TBI, and the incidence has been reported to be as high as 44% [23]. A previous study suggested that hyperglycemia is a transient phenomenon and cannot be used to predict mortality in pediatric TBI patients [45]. In contrast, an association with increased mortality in severe TBI patients has been reported in other studies [23,24,46]. ...

... The PIME team felt that our residents increasingly turn to the Internet when searching for new avenues for professional development. The use of computerbased training in pediatric resident education has a long history [12][13][14][15][16]. In order to provide an educational venue with quality information on CAM in pediatrics, the group developed the Website called HolisticKids.org ...

... Traumatic brain injury (TBI) is the most common cause of mortality in children younger than 16 years of age. It is twice as common as cancer and congenital diseases combined [1][2][3][4][5][6]. Head injury is present in 75% of children with trauma and 70% of all traumatic deaths are due to the TBI [7][8][9][10][11]. ...

... Researchers have been working for years to find protocols that may reduce the number of radiographs used in the assessment of extremity injuries. Ra diologic evaluation of knee injury protocols has also been designed [7][8][9]. The Ottawa and Pittsburgh clinical decision rules have the largest validation cohort in determining the need of x-ray in acute knee in juries [1,2]. ...

... CO has over 200 times the affinity of oxygen for hemoglobin. This causes a decreased perfusion of oxygenated blood to organs and cells leading to organ and cellular damage [10]. Prolonged smoke exposure causes elevated blood levels of CO, which become increasingly toxic, leading to profound hypoxia brain damage and brain death [11,12]. ...