R. T. Hoffmann's research while affiliated with Universitätsklinikum Carl Gustav Carus Dresden and other places

... 3D visualization of liver vividly portraying the presence of healthy and pathological parenchyma of liver followed by volumetric calculation channelize the surgical pre-planning process as a part of treatment procedure to arrive at the optimal resection strategy [8]. Additionally, any increase in liver volume is used as an indicator in the diagnosis of liver pathologies like fatty liver and steatohepatitis [9]. A few works on 3D volumetry analysis of liver and other organs are available in literature. ...

... During development, liver size increases with increasing age, averaging a 5 cm span at 5 years, and attaining an adult size average of about 8.6 cm (male and female) from age 15, with an average volume of 1624 cm 3 [11] and weighing about 1.5 kg. However, the size depends on several factors including age, sex, body size, shape, and to what extent the liver is healthy [ 13,14]. ...

... The prevalence of simple hepatic cysts has been shown to be increasingly common with age [14][15][16][17][18][19] . In addition, according to the study of autosomal dominant polycystic kidney disease (ADPKD), the total hepatic cyst volume increases with age 18 . ...

... Abdominal wall hematomas (AWHs) are characterized by the extravasation of blood inside the muscle layers of the abdominal wall [1][2][3]. ...

... 9 MRI disadvantages are lack of widespread PDFF sequence software availability and cost. 10 Steatosis can be qualitatively graded as mild, moderate or severe based on a combination of ultrasound features: liver-kidney relative echogenicity, vessel wall blurring, ultrasound beam attenuation, presence or absence of focal fat sparing & diaphragm visualisation. 11 However, ultrasound grading of steatosis is subjective, with limited reproducibility and consistency, with 60% -94% sensitivity and 66% -97% specificity for the detection of hepatic steatosis. ...

... Therefore, a scan mode with comparably satisfied image quality and lower radiation dose is particularly important. Compared with acquisition using ultra-high-resolution mode [16,17], which most likely suffers from lower z-coverage and lack of spectral information or other scan modes (i.e., prospective ECG-triggered sequence mode and retrospective ECG-gated helical mode), PCD-CCTA with high-pitch Flash mode provides good image quality with a significantly lower radiation dose and simultaneous spectral information [27,28], especially for patients with low plaque burden. With increasing image quality, possibly due to higher temporal resolution in the third-generation dual-source CT [29] and higher photon efficiency of PCD [9], the threshold above which HR starts impacting diagnostic quality is also increased in CCTA with high-pitch Flash mode [30][31][32]. ...

... However, until recently, the manual annotation required to make true volumetric measurements of the liver from CT and MRI images has been extremely time consuming. Imaging studies tended to rely on more easily measured metrics, such as liver span or diameter [44,45], or calculation of volume indices from the measurement of multiple diameters [46]. Consequently, these approaches limit in depth morphometric assessment and only provide information associated with overall changes to liver size or volume. ...