Nazan Neslihan Doğan's research while affiliated with Adventist University of Health Sciences and other places

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Publications (5)

Maternal and neonatal micronutrient levels in newborns with CHD
Article
  • Jan 2018
Objective It is suggested that folic acid and/or multivitamins, taken periconceptionally, have a role in the prevention of many congenital anomalies. The aim of this study was to determine the serum micronutrient levels in mother–infant pairs with CHD compared with those with healthy newborns and their mothers. Methods Serum levels of folic acid,...
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MaFOS-GDM trial: Maternal fish oil supplementation in women with gestational diabetes and cord blood DNA methylation at insulin like growth factor-1 (IGF-1) gene
Article
  • Dec 2017
Background: To evaluate the effects of maternal fish oil supplementation in women with gestational diabetes mellitus (GDM) on birthweight and DNA methylation at insulin like growth factor-1 (IGF-1) gene in their offspring. Methods: Randomized controlled trial. A total of 120 women with GDM were randomized to one of the two groups between 24 and...
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Congenital Chylothorax in a Newborn with Down Syndrome
Article
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  • Apr 2017
In the neonatal period, the most common cause of pleural effusion is idiopathic congenital chylothorax. Congenital chylothorax is rarely associated with chromosomal abnormalities, such as Down, Turner and Noonan syndromes. The diagnosis can be made after analysis of the pleural fluid drained by thoracentesis or chest tube placement. During the neon...
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Figure 1. Diff use cortical thickening (hyperostosis) and periosteal...
Neonatal cortical hyperostosis secondary to prolonged use of prostaglandin E1 in a patient with pulmonary atresia
Article
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  • Jan 2016
Pulmonary atresia is a rare congenital cardiac malformation. The newborns with this anomaly are ductus dependent to maintain a continuous and adequate pulmonary blood fl ow. As spontaneous closure of the ductus is expected after few hours or days after birth, the patency of ductus should be provided by prostaglandin E1 (PGE1) while the patient is a...
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Citations

... Short term usage of prostaglandin predisposes patients to some of the common adverse effects such as apnoea, respiratory depression, pyrexia, skin flushing and diarrhoea. 1,2 Prostaglandin induced bony changes is a less common side effect 1-3 and the severity is related to the dosage and duration of prostaglandin infusion 3,4 The pathogenesis of hyperostosis due to prostaglandin is not fully understood though prostaglandin can stimulate both bone formation and resorption. 4 Prostaglandin is metabolised rapidly in the lungs and liver via the first pass metabolism. ...
Reference: Cortical hyperostosis, rare adverse effect of prostaglandin
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... One study found no association between zinc levels and CHDs (4), while another showed an inverse relationship between serum zinc levels and the occurrence of ventricular septal defects (VSD) (7). Another piece of research indicated that patients with CHD had higher zinc levels compared to healthy controls (8). ...
Reference: Vitamin D and Zinc Deficiency in Children with Congenital Heart Defects
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... Growing data indicate that the development of diabetes-related vascular disease in progeny is influenced by epigenetic changes through DNA methylation in GDM [102][103][104][105][106]. Genomic stability and gene expression are controlled by DNA methylation. ...
Reference: Human Cord Blood Endothelial Progenitor Cells and Pregnancy Complications (Preeclampsia, Gestational Diabetes Mellitus, and Fetal Growth Restriction)
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