Min Liang's research while affiliated with First Affiliated Hospital of China Medical University and other places
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Publications (13)
Background
Frailty is a dynamic geriatric condition. Limited studies have examined the association of the triglyceride-glucose (TyG) index and its related indicators [TyG index, triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose-waist circumference (TyG-WC), and triglyceride glucose-body mass index (TyG-BMI)] with frailty,...
Background and aims
Ankle brachial index (ABI) is a risk factor for cardiovascular mortality, but it is unclear whether ABI is associated with cardiovascular mortality in patients with nonalcoholic fatty liver disease (NAFLD). The current study aimed to evaluate the association between ABI with cardiovascular and all-cause mortality in patients wit...
Objectives:
To investigate the association between habitual tea consumption and transitions between frailty states among older adults in China.
Design:
A prospective cohort study based on the Chinese Longitudinal Healthy Longevity Study.
Setting and participants:
A total of 23,720 older adults aged ≥65 years with complete data regarding frailt...
The ravages of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide have sped up the development of relevant vaccines, which is accompanied by public concerns over possible adverse effects. We report a rare case of a 39-year-old woman who suffered from severe hyperglycemia and ketoacidosis with normal hemoglobin A1c four days afte...
Purpose:
To explore the relationship between hemoglobin levels and osteoporosis and the risk factors for osteoporosis in patients with type 2 diabetes mellitus (T2DM).
Patients and methods:
A cross-sectional study was conducted in 495 T2DM adults. Medical data were collected from electronic medical records.
Results:
T2DM patients with osteopor...
Glucocorticoid (GC)-induced osteoporosis (GIOP) is the most common type of secondary osteoporosis. Osteoblast apoptosis induced by GCs is now considered as a crucial factor for GIOP. Many clinical, in vivo, and in vitro studies have shown that metformin has a beneficial effect on bone metabolism and bone formation. To investigate whether metformin...
Objectives:
Osteoblasts play an important role in the process of osteogenesis and prevention of osteonecrosis. Dexamethasone, a type of glucocorticoids (GCs), induce apoptosis of osteoblasts and lead to the occurrence of non-traumatic osteonecrosis. This study aimed to explore the effects of different doses and duration of Dexamethasone on osteobl...
Background & AimsNonalcoholic fatty liver disease (NAFLD) is considered as the main cause of chronic liver disease, so the prediction of NAFLD in high-risk cohort of patients would be valuable. Although evidence indicates that anthropometric clinical indicators has been a worthy choice in the prediction of NAFLD, there is no consensus on which is t...
This study aimed to investigate the association between mean platelet volume (MPV) and metabolic syndrome (MetS) in patients with type 2 diabetes mellitus (T2DM). Data for 1240 patients with T2DM admitted to the Department of Endocrinology at the First Affiliated Hospital of Guangxi Medical University between January 1, 2017 and June 1, 2020 were c...
Purpose:
Several previous reports have highlighted the association between adiposity and risk of metabolic syndrome (MetS). Although it is necessary to identify which adiposity indices are best suited to identify MetS, no such study has been completed in diabetic patients. The aim of this study was to evaluate the ability of eight anthropometric i...
This retrospective study aimed to investigate the relationship between hemoglobin (Hb) levels and non-alcoholic fatty liver disease (NAFLD) in patients with young-onset type 2 diabetes mellitus (T2DM). Data were collected for 296 patients with young-onset T2DM admitted to the first Affiliated Hospital of Guangxi Medical University from May 2017 to...
Type A insulin resistance syndrome (TAIRS) is a rare subtype of congenital insulin resistance (IR), which is characterized by specific clinical manifestations without clear diagnostic criteria and is easily misdiagnosed or overlooked. Herein we present a case of TAIRS with acanthosis nigricans (AN), severe IR, polycystic ovaries, hyperandrogenism a...
The hypofunction of osteoblasts induced by glucocorticoids (GCs) has been identified as a major contributing factor for GC-induced osteoporosis (GIO). However, the biological mechanism underlying the effect of GC in osteoblasts are not fully elucidated. Recent studies implicated an important role of phosphoinositide 3-kinase (PI3K)/protein kinase B...
Citations
... Emerging evidence has suggested the habitual consumption of green tea and coffee as a potential modifiable factor for the prevention of frailty and/or sarcopenia (8)(9)(10)(11)(12)(13). Although the biological mechanisms by which habitual consumption of green tea and coffee affects SMM and skeletal muscle function have not been fully elucidated, it has been suggested that various antioxidant and anti-inflammatory pathways induce autophagy and differentiation of myogenic stem cells because of the active ingredients in green tea and coffee, polyphenols (tea catechins and chlorogenic acid) and caffeine, and may prevent age-related decline in SMM and muscle strength (13)(14)(15)(16). ...
... FT1D development following SARS-CoV-2 secondary infection is an exceedingly rare condition which can nevertheless endanger life due to rapid progression to diabetic ketoacidosis and almost complete failure of the pancreatic islet β cells. To date, six cases of newly diagnosed FT1D after SARS-CoV-2 vaccination have been reported [4] while only one case of new-onset FT1D caused by SARS-CoV-2 has been reported [5]. In contrast to previous reports, our case represents the sole instance aligned with the diagnosis of FT1D caused by a secondary SARS-CoV-2 infection. ...
... With the change of lifestyle, diabetes mellitus has become one of the most important diseases affecting people's lives. 1 Studies have shown that type 2 diabetes mellitus (T2DM) accounts for 90-95% of all diabetes mellitus. 2 The number of persons with T2DM are far higher in China than in any other country. The age-standardized prevalence of diabetes mellitus was 9.6 per 1000 person-years for men and 9.2 per 1000 person-years for women. ...
... 20 Similar conclusions have also appeared in other reports. 21,22 Moreover, puerarin-promoted autophagy also plays a positive role in the survival of osteoblast precursors. 13 Accordingly, the relationship between autophagy and apoptosis during osteoblastogenesis under the intervention of puerarin is also worthy of further exploration. ...
... Thirty-seven studies [5, defined MetS according to the third report of the National Cholesterol Education Program-Adult Treatment Panel. [47] Fifteen studies [6,[48][49][50][51][52][53][54][55][56][57][58][59][60][61] assessed metabolic syndrome using the International Diabetes Federation criteria. [62] Seven studies [63][64][65][66][67][68][69] used the Downloaded from http://journals.lww.com/md-journal by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCy wCX1AWnYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC4/OAVpDDa8K2+Ya6H515kE= on 03/12/2024 harmonized criteria. ...
... A study conducted in Spain by Veronica Davila-Batista et al. found that the CUN-BAE index was more strongly associated with cardiometabolic conditions, including diabetes, arterial hypertension, and metabolic syndrome (Mets), compared with BMI and WC, suggesting that CUN-BAE may be better than BMI in identifying individuals at risk for cardiometabolic disease 17 . Xintong Guo et al. found that the association between CUN-BAE and metabolic syndrome was stronger than BMI, WHtR, and other indicators in diabetic patients over 60 years of age 29 . In addition, Vicente Martín et al. found that CUN-BAE showed a positive association with hypertension and diabetes and presented a better gradient than BMI in a population of adults over 18 years of age 18 . ...
... RBC ≥ 470×10 4 /µL and Hb ≥ 14.2 mg/dL were also identi ed as predictors for VFA ≥ 100 cm 2 in single regression analysis in the present study. High Hb levels have been signi cantly associated with the presence of non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes, especially in men [35]. Hb was also signi cantly associated with insulin resistance [36] and free fatty acid deposition in the liver increased insulin resistance in NAFLD [12]. ...
... The mutation in this patient has previously been reported [10][11][12] . It has also been reported in women with symptomatic hypoglycemia. ...
... Kratchmarova and Blagoev et al. discovered that the PI3K pathway is activated in MSC after treatment with plated-derived growth factor (PDGF) and resulted in suppressed osteogenic differentiation [64]. Another study showed that dexamethasone can suppress osteogenesis of osteoblast via the PI3K-Akt pathway in vitro and in vivo [65]. ...
