Kumar S's scientific contributions

... However, few cases of disseminated cryptococcosis have been reported in immunocompetent individuals. Cryptococcal fungal infection is the most devastating and severe infection frequently observed in immunosuppressed individuals such as haematological malignancies, recipients of solid organ transplants who require ongoing immunosuppressive therapy, patients with advanced HIV infection, and persons whose medical conditions necessitate long-term glucocorticoid therapy, and CD4 count <200/microliter [3]. However, multiple case reports and series described the occurrence of cryptococcal infection and other opportunistic infections in patients not known for any immunocompromised condition rather than having a low CD4 cell count, the cause of which was not determined, called Idiopathic CD4 T cell Lymphocytopenia (ICL) [4,5]. ...