Jin Young Ahn's scientific contributions

... Studies have reported dissociations between amyloid deposition and cognitive decline in healthy controls and subjects with MCI and AD (Jack et al., 2009) while others have found associations between amyloid burden and poorer cognitive performance (Kennedy et al., 2012;Rodrigue et al., 2012) and even changing associations based on the disease stage (Chetelat, 2013;Jack et al., 2009;Naslund et al., 2000;Villemagne et al., 2013). The potential predictive power of DTI on cognition has been less explored, but there is evidence that DTI values correlate with decline in working memory in healthy elderly (Bendlin et al., 2010a;Charlton et al., 2006;Pfefferbaum et al., 2000;Raz et al., 2010), and significant correlations between measures of white matter and AD symptom severity have been found, suggesting that measures of WM could be used to measure disease progression in the symptomatic phases of AD (Heo et al., 2009;Sexton et al., 2011). Recent publications using the same cohort as the present study revealed that amyloid is not associated with cognitive decline in these relatively young subjects (Johnson et al., 2013). ...

... These are crescendo-decrescendo bursts of saccades that occur during attempted fixation in patients with cerebellar disease (Fig. 22) [272]. The intersaccadic intervals are normal [273,274]. 4. Ocular flutter and opsoclonus. These are bursts of inappropriate saccades without an intersaccadic interval. ...