Jian-Xia Xu's research while affiliated with First Affiliated Hospital of China Medical University and other places

Publications (19)

Article
To identify important MRI features to differentiate hepatic mucinous cystic neoplasms (MCN) from septated hepatic cysts (HC) using random forest and compared with logistic regression algorithm. Pathologically diagnosed hepatic cysts and hepatic MCNs with pre-operative contrast-enhanced MRI in our hospital from 2010 to 2023 were collected and only s...
Article
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Objective: Hashimoto's thyroiditis is an inflammatory disease, and research suggests that a low-carbohydrate diet may have potential anti-inflammatory effects. This study aims to utilize Dixon-T2-weighted imaging (WI) sequence for semi-quantitative assessment of the impact of a low-carbohydrate diet on the degree of thyroid inflammation in patients...
Article
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Objective To identify CT features and establish a nomogram, compared with a machine learning-based model for distinguishing gastrointestinal heterotopic pancreas (HP) from gastrointestinal stromal tumor (GIST). Materials and methods This retrospective study included 148 patients with pathologically confirmed HP (n = 48) and GIST (n = 100) in the s...
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This study aimed to explore the magnetic resonance imaging (MRI) features of dual-phenotype hepatocellular carcinoma (DPHCC) and their diagnostic value.The data of 208 patients with primary liver cancer were retrospectively analysed between January 2016 and June 2021. Based on the pathological diagnostic criteria, 27 patients were classified into t...
Preprint
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Objective: To identify CT features and establish a nomogram, compared with a machine learning-based model for distinguishing heterotopic pancreas (HP) from gastrointestinal stromal tumor (GIST). Materials and methods: This retrospective study included 148 patients with pathologically confirmed HP (n = 48) and GIST (n = 100) in the stomach or small...
Article
Full-text available
Objective To establish a logistic regression model based on CT and MRI imaging features and Epstein-Barr (EB) virus nucleic acid to develop a diagnostic score model to differentiate extranodal NK/T nasal type (ENKTCL) from diffuse large B cell lymphoma (DLBCL). Methods This study population was obtained from two independent hospitals. A total of 8...
Article
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Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor with an extremely poor prognosis and low survival rate. Due to its inconspicuous symptoms, PDAC is difficult to diagnose early. Most patients are diagnosed in the middle and late stages, losing the opportunity for surgery. Chemotherapy is the main treatment in clinical practice and...
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Objective To investigate clinical characteristics, radiological features and biomarkers of pancreatic metastases of small cell lung carcinoma (PM-SCLC), and establish a convenient nomogram diagnostic predictive model to differentiate PM-SCLC from pancreatic ductal adenocarcinomas (PDAC) preoperatively. Methods A total of 299 patients with meeting...
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PurposeTo assess contrast-enhanced computed tomography (CE-CT) features for predicting malignant potential and Ki67 in small intestinal gastrointestinal stromal tumors (GISTs) and the correlation between them.Methods We retrospectively analyzed the pathological and imaging data for 123 patients (55 male/68 female, mean age: 57.2 years) with a histo...
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Objective: The purpose was to compare the accuracy of extraprostatic extension (EPE) grade on MRI predicting EPE with Partin tables, Memorial Sloan Kettering Cancer Center nomogram (MSKCCn), and combined models and to analyze the clinical incremental value of EPE grade. Materials and methods: 105 prostate cancer patients confirmed by pathology a...
Article
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Background Xanthogranulomatous cholecystitis (XGC) is a rare benign chronic inflammatory disease of the gallbladder that is sometimes indistinguishable from gallbladder cancer (GBC), thereby affecting the decision of the choice of treatment. Thus, this study aimed to analyse the radiological characteristics of XGC and GBC to establish a diagnostic...
Article
We aimed to further explore the CT features of gastric schwannoma (GS), propose and validate a convenient diagnostic scoring system to distinguish GS from gastric gastrointestinal stromal tumors (GISTs) preoperatively. 170 patients with submucosal tumors pathologically confirmed (GS n=35; gastric GISTs n=135) from Hospital 1 were analyzed retrospec...
Article
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Background Renal angiomyolipoma without visible fat (RAML-wvf) and clear cell renal cell carcinoma (ccRCC) have many overlapping features on imaging, which poses a challenge to radiologists. This study aimed to create a scoring system to distinguish ccRCC from RAML-wvf using computed tomography imaging. Methods A total of 202 patients from 2011 to...
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Background To investigate characteristic clinical and imaging features and establish a scoring system for preoperative prediction of malignancy in the bulging duodenal papilla. Methods A total of 147 patients with bulging duodenal papilla (Benign enlargement n = 67; malignant enlargement n = 80) from our hospital between 2010 and 2020 were retrosp...
Article
Objectives To investigate CT findings and develop a diagnostic score model to differentiate GLMs from GISTs. Methods This retrospective study included 109 patients with pathologically confirmed GLMs (n = 46) and GISTs (n = 63) from January 2013 to August 2018 who received CE-CT before surgery. Demographic and radiological features was collected, i...
Article
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To improve the detection of prostate cancer (PCa) by combining the Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) and prostate-specific antigen–age volume (PSA–AV), especially among those in gray zone with PI-RADS v2 score 3 or serum total prostate-specific antigen (tPSA) 4 to 10 ng/mL. The 357 patients were enrolled in this stud...
Article
Full-text available
Objective To investigate the CT and MR imaging findings and differential diagnosis of malignant vascular tumors of bone. Materials and methodsCT and MR imaging findings of 18 patients with histopathology-proven malignant vascular tumors of bone were examined. Assessed image features included age, sex, location, CT findings, and MR imaging appearanc...
Article
This study aims to evaluate the intraobserver and interobserver reproducibility of the tophus urate volume, erosion volume, and the erosion score measurements in patients with gout by using dual-energy CT (DECT) scans comparing their bone erosion volumes against bone erosion scores and also to determine a valid measure of joint destruction in chron...

Citations

... These innovative technologies are now being applied across the spectrum of HCC management, from enhancing screening and early diagnosis to improving tumor characterization, prognostication, and personalized therapy selection as depicted in Table 1 [10], [11], [12]. [13], [14], [15], [16], [17], [18], [19], [20], [21], [22] ML analysis of ultrasound images Convolutional neural networks (CNNs) identify subtle imaging traits of early HCCs Diagnosis and Staging [23], [24] Deep learning on computed tomography (CT)/magnetic resonance imaging (MRI) scans CNNs differentiate HCC from other liver lesions Prognostication [25], [26] ML models with clinical, imaging, genomic data ...
... 3 Clinical and scientific efforts have been made to develop novel treatment approaches for PDAC. [4][5][6][7] Thus, exploring potential molecular targets and underlying mechanisms in pancreatic carcinogenesis and tumor progression is urgently needed for the early diagnosis and identification of additional effective treatments for PDAC. ...
... Discussions on lung cancer spreading to the pancreas are scarce, yet small-cell lung carcinoma is more inclined to develop pancreatic metastasis compared to adenocarcinoma or squamous-cell carcinoma. This type of metastasis from small-cell lung carcinoma often presents as a single nodular lesion, closely resembling a primary pancreatic tumor [9]. In a study of 850 lung cancer patients, Maeno et al. found that 26 patients (3%) had pancreatic metastases, primarily presenting as a single nodule (73%), multiple nodules (11.5%), or diffuse swelling (15.4%). ...
... To some extent, this reflects the resolution limitations of multiparametric MRI pulse sequences and our practice of conservative readings [29]. The T3 stage is a significant pathological characteristic of PCa, which raises the likelihood of PSMs and biochemical recurrence [30]. However, identifying the T3 stage from MRI is often considered to be subjective. ...
... Most studies on the preoperative diagnosis of XGC and GBC focus on their differential diagnosis using various preoperative imaging examinations (10,24,25). However, reports on the demographics, clinical symptoms, and laboratory tests of XGC and GBC patients are scarce. ...
... All the lymph nodes with FDG were proved to be reactive hyperplasia by postoperative pathology [3]. Perilesional lymph nodes were important signs distinguishing gastric schwannoma from gastric stromal tumor [7]. Similarly, esophageal tumors with benign characteristics and peritumoral lymph nodes may improve confidence in the diagnosis of schwannoma. ...
... The technique produced segmentation results with mean Dice coefficients of 0.917 in non-contrast-enhanced sequences and 0.904 in secretinenhanced sequences. Zhou et al. [29] aimed to develop a diagnostic prediction model for differential diagnosis and clinical decision-making based on clinical data and radiological characteristics of Xanthogranulomatous cholecystitis, a rare benign chronic inflammatory disease of the GB. They used LR and a RF approach to validate relevant clinical data and radiological characteristics. ...
... The best imaging for diagnosing renal angiomyolipoma is CT and CTA [3.6] In Wang et al.'s study, CT features for differentiating RAML from liposarcoma, such as intratumoral linear vessels, aneurysmal dilation of intramural vessels, beak signs, hematomas, and discrete internal and intrarenal fatty tumors, are mentioned [7]. An MRI with CT can also help in diagnosing the connection of renal vessels with ERAML [8]. ...
... 9 The size of the mass and irregular shape were described as the valuable independent variable to differentiate ampullary tumors from benign papillary stricture. 10 MRI with MRCP may be equivalent to MDCT for identifying a bulging papilla and superior for distinguishing the underlying cause which is a crucial fact. Malignant papillary carcinomas often present as small lesions when diagnosed because of the relatively early onset of symptoms, which may be difficult to distinguish from other causes due to not being evident in images. ...
... (3) The incidence of small bowel tumors is low; however, among them, the incidence of stromal tumors is high. The tumor in this case was rounded, with a rich blood supply, and the lesion showed obvious enhancement, which is consistent with the imaging manifestations of gastrointestinal tumors (18,19). ...