Irina Shanidze's scientific contributions

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Publication (1)

Fig. 1. Representative polygraph segment from a subject during stable...
Table 2 . Results of episodic hypoxia presented as grouped data for...
Fig. 6. Diagramatic representation of the relationship between V ˙ I...
Effect of episodic hypoxia on the susceptibility to hypocapnic central apnea during NREM sleep
Article
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  • Nov 2009
We hypothesized that episodic hypoxia (EH) leads to alterations in chemoreflex characteristics that might promote the development of central apnea in sleeping humans. We used nasal noninvasive positive pressure mechanical ventilation to induce hypocapnic central apnea in 11 healthy participants during stable nonrapid eye movement sleep before and a...
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Citations

... Changing the prevailing oxygen level in humans resulted in the narrowing and widening of the CO 2 reserve during hypoxia and hyperoxia, respectively [19]. Similar effects were noted when hypoxia was administered as intermittent hypoxia, mimicking recurrent apnea [20]. Conversely, breathing a hyperoxic mixture results in widening of the CO 2 reserve [21]. ...
Reference: Central Sleep Breathing Disorders: A Critical Evaluation of Classification and Diagnosis
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