Hongzhe Li's scientific contributions
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Publications (3)
Motivation:
Association analysis of microbiome composition with disease-related outcomes provides invaluable knowledge towards understanding the roles of microbes in the underlying disease mechanisms. Proper analysis of sparse compositional microbiome data is challenging. Existing methods rely on strong assumptions on the data structure and fail t...
Citations
... To detect a significant taxa at the phyla, family or genera level associated within the two clusters generated from PCA analysis, the Quasi-Conditional Association Test using General Estimating Equations (QCAT-GEE) was used, including a Permutation test 36 . The QCAT-GEE composes of three tests: the zero-test, which assess presence or absence of taxa, the positive-test, which assesses differences in abundance of each taxa, and the twotest, which combines the zero and positive-tests. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/280084599590912-1443788780129_Q64/Guanhua-Chen-2.jpg)
