G. H. McCracken's scientific contributions

Citations

... Hemolysin-coregulated protein (Hcp) and valine glycine repeat (VgrG) are both considered to be the hallmarks of T6SS and show considerable homology to essential proteins that form the punctuating injector of a typical bacteriophage (Brunet et al., 2014). Since the discovery of its first member in V. cholerae as part of the T6SS machinery (McCracken et al., 1984;Ishikawa et al., 2009), the Hcp family proteins have been identified in a variety of bacterial species. An Hcp1/Hcp2 double knockout of V. cholerae V52 was generated by transposon mutagenesis and showed no virulence on Dictyostelium discoideum (Pukatzki et al., 2006). ...