Fatemeh Rahimianfar's research while affiliated with Shahid Sadoughi University of Medical Sciences and Health Services and other places

Hypertension (HTN) is one of the most common disorders and increases the risk of cardiovascular diseases (CVD), which are one of the main causes of death in the world. The Mediterranean diet has the efficacy to modulate CVD risk factors such as HTN, mainly because of olive tree products, which are the most pivotal ingredients in this diet. Among the olive tree products, olive leaf consists of many sorts of phenolic compounds and has several beneficial effects on human body, such as antioxidant, anti-atherosclerotic, anti-inflammatory and especially anti-hypertensive effects. So, we conducted a new systematic review and meta-analysis on anti-hypertensive effect of OLE in adults. The meta-analysis showed a significant reduction effect of OLE on systolic blood pressure. The anti-hypertensive effect of OLE is mainly considered due to its principal phenolic compound known as oleuropein (OL), which reduces blood pressure by a number of particular mechanisms associated with its specific chemical characteristics.

The aim of this study was to determine the effect of low-dose propofol on the respiratory complications immediately after tracheal extubation in children undergoing tonsillectomy. In this randomized double blinded clinical trial study, 70 children (2–12) years old with ASA class I undergoing elective tonsillectomy involved. General anesthesia was performed by the same anesthesiologist and in the same way. The patients were then intubated with oxygen after 3 min of ventilation. After the surgery and muscle relaxant injection and before extubation, 0.5 mg propofol/kg was injected into the intervention group. The control group received normal saline. Finally, the presence of post-extubation laryngospasm, cough and nausea and vomiting was recorded and all data analyzed between two groups. There was no significant difference in age (p value = 0.425), gender (p value = 0.851), cough (p value = 0.239), nausea (p value = 1) and weight (p value = 0.624) between two groups. There was a significant different in incidence of laryngospasm between two groups (p value = 0.04). It can be concluded that the administration of 0.5 mg/kg of propofol before extubation could prevent laryngospasm in patients undergoing tonsillectomy, without inducing any side effects.

Background: The infants with congenital cardiovascular diseases are faced with too much problems in the case of their ongoing life. Mothers' stress investigation would be important because can receive the stress from his parents. The aim of the following study was determined anxiety in mothers of children undergoing cardiac surgery. Materials and methods: The present study was conducted by an analytical study on 69 infants' mothers who were operated due to their cardiovascular abnormalities in Yazd Afshar Hospital (2012). In this study, some demographic information and influential factors were recorded germane to mothers' stress, including residential location, history of infant hospitalization or congenital disease as well as some questions in the case of stimuli of the hospital environment, family support, economic situation and the mothers' awareness of their stress. Results: There are statistically significant differences between mothers' stress and their age (P = 0.03) and infants' age (P < 0.0001). There are not statically significant differences between mothers' stress score mean and their educational level (P = 0.75), the infants' hospitalization history (P = 0.57), the history of congenital of disease in family (P = 0.24) and the family support in infant care (P = 0.08). Conclusion: Those mothers who asserted the stimuli of the hospital environment, infant and its mother support, economic situation and the mothers' awareness lack of disease and infant status as strong stress-making stimuli enjoy a stress high mean.

Objective: One of the major complications of cardiac surgery is the presence of post-operative bleeding. The aim of the present study was to investigate the topical application of tranexamic acid in the pericardial cavity on post-operative bleeding in off-pump coronary artery bypass graft (CABG) surgery. Materials and Methods: This study was on 71 patients who underwent off-pump CABG. The anesthesia and surgery methods were the same for all patients. Patients were assigned to two equal groups. In the first group, 1 g of tranexamic acid in 100 mL of normal saline solution (NSS) was applied to pericardium and mediastinal cavity at the end of surgery. In the second group, only 100 mL of NSS was applied. Chest drainage of the patients after 24 h and the amounts of blood and blood products transfusion were also recorded during this time. Results: Patients were the same regarding demographic information and surgery. The average volume of blood loss after 24 h was 366 mL for the first group and 788 mL for the control group. There was a statistically significant difference between the two groups (P < 0.001). The amount of packed red blood cells transfusion in the first group was less than that of the control group, which was not statistically significant. There was no statistically significant difference between the amount of hemoglobin, hematocrit, platelets, prothrombin time and partial thromboplastin time in the post-operative stage in the two groups. Conclusion: The topical application of tranexamic acid in off-pump CABG patients leads to a decreased post-operative blood loss.