ResearchGate Q&A lets scientists and researchers exchange questions and answers relating to their research expertise, including areas such as techniques and methodologies.
Browse by research topic to find out what others in your field are discussing.
- 1Do you have any suggestions of financial variables, the level of which affects company’s innovation activities?
I assume that financially healthy companies may spend more on innovation activity. For the moment I use the measures of profitability (e.g. margins), liquidity (e.g. current ratio), and leverage. Could you suggest others?
An obvious one is spending on R&D, I would think given that those you identify do not explicitly point to this sort of spending. It may well be that it may come under another heading.
A profitable bank may not be spending on innovation, except perhaps in marketing, and IT. But IT may be off-the-shelf... so financially health is no indicator of interest in innovation.Following
- NewHow would one can define the phenomenon of Disruption at individual level?
Considering Disruptive Innovation as a subset of Innovation with radical characteristics on Market dimension, how would one can define the phenomenon of Disruption at individual level? Or to say Disruptive output of an individual? Comments and thoughts are welcomed.Following
- 6What is the most weakness muscle in the quadriceps in aging?
If muscle decline in sarcopenia, may it have effect in VMO or VL ?
How is the balance between VMO VL in aging?
Thanks you very musch.Following
- 1What are the best markers for rat macrophages, fibroblasts, Scwann cells and PNS axons for IHC in frozen sections?
I am currently working on peripheral nerve repair on rats after transection injury. I would like to visualise macrophages, proliferating fibroblasts and Scwann cells, and growing axons in frozen sections using IHC chromogenic methods. Can anybody suggest the best target markers for such application?
for macrophages you can use CD11, for fibroblast you can use vemintinFollowing
- NewWho are the great authors in Organisational politics' influence on both organisational citizenship behaviour and leadership?
articles of organisational politics' impact on organisational citizenship behaviour and leadershipFollowing
- 95Can we design the orbit of a satellite with Einstein’s curved space?I think that the most successful theory of gravity is that the orbit of planet can be explained with this theory and the orbit of satellite was designed with this theory. To design an orbit of a satellite, the three of the factors of the orbit: 1) The radius, 2) The inclination angle, 3) The eccentricity, must be calculated. And, the Newtonian theory of gravity is the only theory that can calculate the three factors. In another words, if there was not the Newtonian theory of gravity, the orbit of the satellite could not be designed. It was known that, from Einstein’s field equation, the orbit of planet can be deduced. And it was used to explain the advance of the Mercury perihelion. But, I cannot find the method to calculate the three factors with Einstein’s field equation.
Kåre, you allways make me read! :-)Following
- 99+Universe is static!!! Yes or no?
Space of Universe is static! Yes or no?
Question: Are there any observations that do not fit into the model static space of Universe, are there any theoretical obstacles to the existence of such a model?
I assume that the Universe is eternal, infinite and static, it is not expanded and not curved, it is possible to construct a preferred inertial frame of reference in which the CMBR is most isotropic. The matter in this space evolves, but the average density of matter and energy (in large enough volumes) fluctuate within a rather broad range.
The light in this model is "tired", the speed of light depends on the optical density intergalactic medium. Gravity is also "tired" t.i. weakens a little faster R2. The energy of destroying matter goes into the surrounding vacuum. The excess energy from the vacuum give rise to new particles of matter.
I state that all the observed cosmological effects can be explained in such a Static Model of the Universe.
See attached "Basic_Cosmological_Formula_1_En.pdf"
Dear colleagues, I do not ask, what are the problems faced by other theories (though I would be interested in your opinion on that. The General theory of relativity is not applicable to the entire space of the Universe).
Every electron can be in principle black hole and universe. Scales is no matter here if Planck's limit is absent. It is old ideas of Markov and other Dubna people from sixties. Seventies is my studentsheap.Following
- 6What is the best method to determine mineral nitrogen in a compost sample with an ultraviolet– visible spectrophotometer?
I looking for method to determine only the amount of mineral nitrogen (NH4, NO3, NO2) but not of organic nitrogen in a compost sample.
For exemple : the Nessler method
Total N can be estimated by combustion method.But incubation method may not estimate all the organic N.It may mineralize only 50 per cent of total organic N.So it is difficult to get mineral N by deducting mineralized organic N from total N.One can extract mineral N by extracting with 2 M KCl and extract clarified by treating with acivated charcoal as suggested by Dr.Paul.After that ammoniacal and nitrate N can be estimated any of the methods suggested by colleagues like Dr.Elephant.Following
- 1Alternative of end note for android tablet ?
Thomson reuters provides endnote app only for ipad not for android. Is there any alternative software for arranging and reading bibliography on android tablet ?
did you check for mendeley?Following
- 1Why do we need to realize the quality control of a medicinal plant?
Please give answer with example.
medicinal plants contain large amount of secondary metabolites which have wide rang of biological effects, the concentration of these substance is largely depend on environmental factors and measuring the quality of these plants can give us a clue of its secondary metabolites qualityFollowing
- 3In which solvent SnO2 nanoparticles will be dissolved?
in which solvent SnO2 nanoparticles will be dissolved?
try ethers or alcohol may be used as solventFollowing
- 3I am looking for sources outlining the phonetic inventory and/or orthographic systems of Early Modern French (1500 to 1750). Any suggestions?
I'm basically looking for any ideas about what the sound patterns of early Quebec French (or corresponding French from France) would have sounded like and/or was represented. Merci!
I've found this information that might be useful.
R. Mougeon & É. Beniak (dir.), 1994. Les origines du français au Québec. Québec: Les Presses de l'Université Laval.
You can read it at:
(see also the table of contents in the document for further references).
There is also this website titled:
DIACHRONIC SOCIOLINGUISTIC RESEARCH ON THE EVOLUTION OF VARIATION IN QUEBEC AND EUROPEAN FRENCH
With reference such as:
Poirier, C. 1975. La prononciation québécoise ancienne d'après les graphies d'un notaire du XVIIe s. Dans M. Juneau & G. Straka (dir.). Travaux de linguistique québécoise, vol. 1. Québec: Les Presses de l'Université Laval, 193-256.
I hope this helps.
With best wishes,
Jose A. MompeanFollowing
- NewIn R, is there any way to read data from the second, third,... sheets of .csv file?
In R programming, I need to import data from excel file. I converted it to .csv file so that the data import bacame fast. But the next problem came as to I was unable to read data from the sheets except the first one. Is there any way to tackle this? My major concern is that importing large amount of data from excel file takes more time as i have data in only the first two columns. Other columns are left blank.Following
- 2Re Masson's trichrome stained tissue. What format (ie., jpeg, Tiff, etc) do I save the image for analysis via Fiji (ImageJ)?
I am interested in quantifying the amount of collagen in lung tissue regardless of thickness of the section. The sections will be imaged in bright field using a Zeiss scope. In addition, I found a video showing step-by-step the analysis using ImageJ. Would others agree with this tutorial?
You can save it as JPEG file and measure by ImageJ easily
I used it to quatify fibrosis in picrosirius stained muscle sections
I just adjusted the threshold and measure
you can refer to my paper
- 5Has anyone ever noticed a changed in morphology of MCF7 breast cancer cells?
I have noticed morphological changes in my MCF7 cells (without any treatment). Has anyone ever experienced this? They went from a "cobble-stone" morphology to a smaller almost epithelial looking morphology.
Do not forget cell croos-contamination.
See the attached comments.
- 82,6-diaminopyridine does not soluble in alcohol, Tell me how i soluble that material in what solvent?
alcohol or some other solvent or mixture of solvents
use Xylene is a solvent. or use water or acetone is also a solventFollowing
- 8Simple method for glutathione peroxiadase measurement ?
Can anybody suggest methods to measure glutathione peroxidase ?
You can measure this activity by kits available in market (Sigma or Aldrich). See for details the folloowing reference:
LAWRENCE, R.A., BURCK, F.B., 1976. Glutathione peroxidase activity in selenium deficient rat liver. Biochem. Biophys. Res. Commun. 71, 952–958.
We have used this kit for determination of GPx in Donax trunculus (see attached this publication).
Best regards N. SoltaniFollowing
- 11What are the philosophical questions raised by gravitational waves?
'On February 11, 2016, the Advanced LIGO team announced that they had directly detected gravitational waves from a pair of black holes merging' (Wikipedia)
This is to invite views what sort of philosophical questions might be implied by this discovery?
The main question is that GW are pure theoretical failure and how is possible that have been discovered?
Prof. Loinger http://arxiv.org/ftp/astro-ph/papers/9906/9906058.pdf
our research group: http://www.sciencepublishinggroup.com/specialissue/122019
How now have been discovered is a big mystery fo me. Here there is something wrong. NATURE is respected journal. I think they are right. GW research is dead. This LIGO resurection of GW will not last long.Following
- 8Can anyone help me on literature of Innovation performance and R&D management practices?
I'm planning to conduct a research on Innovation performance and R&D management practices. Can anyone help me on literature? The tentative topic will be "How the R&D management practices affect on innovation performance in software development industry". The study will be carried out in the Sri Lankan context.
Hi, Again you can read my couple of articles which is not listed in RESEARCHGATE all. Its all others journal. It will be helpful for your literature part.Just type my name KAMAL CHANDRA PAUL,UPM then send. Hope, you will get some answer from my published articles. --Paul,UPMFollowing
- 6How did Einstein identify existence of black holes in those days, with no experimental set up? Can gravitational waves be observed (now or in future)?
There is an on going rumor that an advanced LIGO is about to detect gravitational waves that cause by merging of two black holes! Do you believe the discovery of gravitational waves through experimental setup(now or in future)?
Dear Prof. Toth:
While going through the LIGO article in Physical Review Letters, I noticed that no mention was made about the negative energy of gravity and no mention of zero energy universe on which general relativity stands. It mentions that 3 solar masses x c^2 is the energy lost in collision of two black holes which gets converted into gravitational waves. Now the energy lost is the positive energy and the gravitational waves are the negative energy. So according to zero energy universe both these energies has to annihilate each other and then nothing can reach LIGO to observe. I did not see any of these discussed in the article. Instead it says gravitational waves are due to space like trajectories. The entire energy of the space time fabric is supposed to be negative energy and the gravitational waves are the ripples in this fabric. Can you kindly explain this?
- 2Is there a (statistically based) significance threshold for Pseudo R Square in Ordinal Logistic Regression?
Model with Ordinal Independent Var (Likert scale) and ordinal Dependent var (Likert scale).
Categorical Moderating Var.
For example scores:
Cox and Snell ,161
Thank you for your thorough and knowledgeable answer.
My search of both EBSCO and Google Scholar also delivered no academic papers about this subject.
Your remeark that the two models can be compared is very insightful. I will proceed accordingly.
Working with SPSS. Will check if McKelvey and Zaivona are available.
- NewHow to calculate fixed effects from R plm function?
I used plm function in R and choosed within model,
but it just returned corfficient of the independent variable
how can I calculate the fixed effects?
can I use the formula in the figure I attached?
Thank you so much!!Following
- 10How to calculate IC50 value of DPPH radical scavenging assay?
If I follow this protocol: The antioxidant activity of the extracts was tested using DPPH as previously described with some modifications (Zhang et al., 2011). Briefly, the DPPH free radical scavenging activity of grain extracts was determined using a 2 × 10−4 M DPPH solution. Each sample (0.5 ml) was mixed with 4 ml 2 × 10−4 M DPPH in ethanol. The mixture was shaken, and then left to stand for 60 min in the dark. The absorbance was measured at 517 nm in a spectrophotometer. The absorbance of the control was obtained by replacing the sample with 80% methanol. The DPPH radical scavenging activity of the sample was calculated as follows:
% scavenged= [1- abs of sample/abs of control]x 100
I recommend you with EZ-Fit™ by Perrella Scientific, its simple and accurateFollowing
- 32Why nobody see that Higgs boson and gravitational waves are the pure theoretical failures?
Higgs boson does not interact with gluons which give energy for 99% of proton mass. How the Higgs boson gives mass to the proton, nobody has no clear answer. Why are we closing eyes and tolerating this model which does not have a minimal correspondence with physical existence? Energy and mass are both inherent physical properties of every particle. No particle can give mass to another particle; this is a complete misunderstanding. Higgs boson does not prove anything, Higgs boson is artificially made flux of energy and nothing more.
Energy and mass are both inherent physical properties of every particle. They have the origin in the diminished energy density of quantum vacuum. A given particle cannot be examined without this diminished energy density of quantum vacuum which determines its energy and mass. The idea that particles exist in an empty space deprived of physical properties is the biggest theoretical failure of physics since its existence. It has led to the idea of Higgs field and gravitational waves which are both pure theoretical failure. No particle can give mass to another particle; this is a complete misunderstanding. Higgs boson does not prove anything, Higgs boson is artificially made flux of energy and nothing more. And no wave can transmit gravity.
Luis you have free and independent mind. Main stream physics is fixed by some old ideas which belong to the 20 the century.Following
- 7Can "predator" cancer cells compete with other cancer cells to benefit from the resources in the same tumor clone?
Can "predator" cancer cells compete with other cancer cells to benefit from the resources in the same tumor clone?
Have a look on the attached articles. They could be of interest.
- 2Total phenols in black carrot. I tried to estimate total phenols in black carrot by folin-ciocalteu method. The values are varying with volume?
Carrots are extracted with 80% alcohol
please follow this methodFollowing
- 8Even though, STCR based SSNM studies has been thoroughly done in Agricultural crops, Why research is so scanty in Horticulture using STCR approach??
In the era of sustainability, soil test based fertilizer approach is one of the viable options for the dynamic adjustment of nutrients based on soil fertility status. Even though STCR based SSNM concept emerged in the early 1960's and a lot of research has been done on food grains and cereal crops, why that kind of research has not implemented in flower crops till now. How far it is worthful if we follow in flower crops too???
Ms.Lakshmi, one can use STCR approach for flowers if they are grown under field conditions like vegetable crops.Following
- NewWhat is the important of herbal drug quality control?
Please try to keep the answer short and simple. Thanks!Following
- 4How to work with Matlab?
I recently done a bioreactor model with conventional PI controller. I know when we simulate, the closed loop response and the input is obtained in the scope.
My question is how to evaluate the other studies by using matlab, ie. the concentration study, pH stability, etc.,
My Transfer function for the process is
G(s) = aS+b/S^2+bS+c
a-- product consentration
Is bode plot is necessary for this study?
i was worked with serial port of pc with hardware or i work hardware in the loopFollowing