Del Castillo J's scientific contributions
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Citations
... Simulation-based research, often referred to as the in silico method, is establishing itself as an indispensable tool to bridge physical and temporal scales, enhance insights and accelerate progress in more and more scientific disciplines. In biology, it has long been recognized that mathematical modeling would be required to complement experimental efforts to understand basic principles of life's complexity, ranging from cellular phenomena (Hodgkin and Huxley, 1952;Del Castillo and Katz, 1954;Joyner et al., 1978;Bartol et al., 1991;Stephanova and Bostock, 1995;Tsodyks and Markram, 1997;Nadkarni and Jung, 2007;Coggan et al., 2010;Xylouris and Wittum, 2015) to network behavior (e.g., Eliasmith et al., 2002;Izhikevich, 2004;Migliore et al., 2006), just to name a few. This realization has engendered the creation of multiple simulation environments to address this need ( Bartol et al., 1991;Hines and Carnevale, 1997;Bower and Beeman, 1998;Tomita et al., 1999; Schaff et al., 2000;Eppler et al., 2008). ...