Fabiana N Fonseca

New York Botanical Garden · Economic Botany

Candomblé is an African-Brazilian religion that resulted from the adaptation of West African (especially Yoruba) beliefs in Brazil during and after the slave trade. This study seeks to understand the current evolution of Candomblé ethnobotanical knowledge as it travels from Brazil to New York City (NYC), therefore going through a second adaptation...

The study objective was to evaluate the composition of a neutral and weakly acidic water-soluble extract from Echinacea purpurea (L.) Moench (EchNWA) previously shown to modify murine influenza infection, and to assess immunomodulatory effects on human T-cells. EchNWA extract from fresh aerial parts was extracted with water, ethanolic precipitation...

The study evaluates the chemical composition of an Echinacea purpurea (EchNWA) extract previously shown to modifiy the course of influenza infection in a mouse model and assessed immunomodulatory effects on human T-cells. EchNWA extract was obtained from fresh aerial parts extracted with water, followed by ethanolic precipitation, and size-exclusio...

This article explores the use of capillary electrochromatography for the analysis of chamomile (Chamomilla recutita L.) extracts. After a thorough study of analytical parameters such as mobile and stationary phase composition, applied voltage, and temperature, a methodology to determine 11 bioactive phenolic compounds (coumarins: herniarin, umbelli...

Although many proteasome inhibitors have been either synthesized or identified from natural sources, the development of more sophisticated, selective proteasome inhibitors is important for a detailed understanding of proteasome function. We have found that antitumor natural product epoxomicin and eponemycin, both of which are linear peptides contai...

Genetic loss of function analysis is a powerful method for the study of protein function. However, some cell biological questions are difficult to address using traditional genetic strategies often due to the lack of appropriate genetic model systems. Here, we present a general strategy for the design and syntheses of molecules capable of inducing...

A capillary electrophoretic method for the quantification of free and total apigenin in methanolic, ethanolic and glycolic extracts of Chamomilla recutita L. Rauschert (Asteraceae) is described. The method was validated for measurement of apigenin in the range 5.00-300 microg/mL (r2 = 0.993) and showed coefficients of intra-day (replicability) and...

This work presents a comparative evaluation of electrolyte systems for the capillary electrophoresis analysis of the phenolic compounds apigenin and luteolin, and their corresponding 7-O-glucosides naringenin, rutin, quercetin, umbelliferone, herniarin, chlorogenic, and caffeic acids, in methanolic, glycolic, and hydroalcoholic extracts of Matricar...

Chemical investigations carried out with tissues at different developmental stages of Araucaria angustifolia established the presence of E and Z isomers of octadecyl p-coumarate and octadecyl ferulate in undifferentiated callus; in the seedling stems, the source of explants, three biflavones of the amentoflavone-type were isolated, whereas the dite...

O uso das plantas medicinais confunde-se com a história do ser vivente. Desde a idade da pedra até meados do século XX elas constituiram a principal fonte medicamentosa para a nossa sociedade. Hoje o mercado de fitoterápicos e fitocosméticos vêm movimentando bilhões de dólares a cada ano. Apesar de possuir representantes de cerca de þ70 POR CENTOþ...

O estudo fitoquímíco do extrato etanólíco de caules adultos de Araucáría angústia resultou no isolamento e ídentificação da vanilina, p-hidroxibenzaldeido, coniferaldeído, dois isoflavonóídes (cabreuvina e irísolidona), quatro lignanas(pinoresinol, eudesmina, lariciresinol) e 'BETA'-0-acetato de lariciresinol) e þBETAþ-sitosterol. Foi desenvolvido...