There is limited data regarding differences in patency and clinical outcomes of patients with life style limiting claudication and Critical Limb Ischemia (CLI).
Retrospective data analysis was conducted from the ongoing XLPAD registry between July, 2005-October, 2013 to report clinical and revascularization outcomes of Superficial Femoral (SFA), Popliteal and Below the Knee (BTK) vessels for
... [Show full abstract] Claudicants vs. CLI.
A total of 559 interventions were performed on 343 patients (Claudicants 77% vs. CLI 23%). Diabetes Mellitus and Chronic Kidney disease were more prevalent in the CLI group as compared to Claudicants (71.8% vs. 54%, p<0.01 and 30.8% vs. 13.4%, p<0.01 respectively). Stent implantation was significantly lower in CLI patients (67.1% vs. 47.6%, p<0.01 respectively). Lesion lengths and frequency of chronic total occlusions were similar in both groups (105.3 ± 80.4 vs. 122.1 ± 77.6, p=0.08; 65.0% vs. 75.1%, p=0.2 respectively). Statin therapy was lesser used in CLI as compared to Claudicants (76.1% vs. 87.3%, p=0.05).Although repeat revascularization rates were similar in both groups (16.2% vs. 17.6%, p=0.7 respectively), surgical revascularization and amputation rates were higher in CLI (14.5% vs. 4.9%, p<0.01 and 27.4% vs. 1.6%, p<0.01 respectively. Likewise, mortality rates were also higher in the CLI cohort (9.4% vs. 3%, p=0.008).
CLI patients have lower rates of stenting but significantly higher frequency of surgical revascularization and amputations.