Aziz Gültekin

Pamukkale University · Department of Nuclear Medicine

Transarterial radioembolization (TARE) is a widely used treatment method for primary liver cancers and metastasis. Although TARE is relatively safe, it may cause liver abscess, failure, nontarget embolization, and vascular complications. Herein, we report a case of TARE-related hepatic artery pseudoaneurysm that was treated successfully with ultras...

Objective: The role of baseline and post-treatment standardized uptake value (SUVmax) values in predicting pathological response in patients with breast cancer after neoadjuvant chemotherapy (NAC). Materials and methods: Thirty patients with invasive ductal breast cancer were included in this retrospective study. F-18 fluorodeoxyglucose (FDG) po...

The review titled “Good practices for 68Ga radiopharmaceutical production” by Nelson et al. (2022) and published in the latest issue of your journal contains important information about 68Ga radiopharmaceuticals. However, sentence of the “These 68Ga radiopharmaceuticals include agents such as [68Ga]Ga-macroaggregated albumin for myocardial perfusio...

Objectives In this study, we aimed to investigate the correlation between SUVmax of primary tumor and prognostic factors/molecular subtype in ductal breast cancer patients. Materials and methods We retrospectively reviewed 150 female patients with pathologically proven invasive ductal breast cancer from January 2015 to October 2019 who underwent ¹...

An 83-year-old male patient presented with recurrent high fever. Vegetation was determined on transesophageal echocardiography, and antibiotic treatment was initiated for infective endocarditis. Despite medical treatment, progressive aortic insufficiency occurred and aortic valve replacement was performed. However, C-reactive protein (CRP) and feve...

PurposeThe generator product radionuclide gallium-68(68Ga) is widely used for PET/CT imaging agents and the 68Ga-labeled MAA is an attractive alternative to 99mTc-labeled MAA. Using a commercially available MAA labeling kit for 99mTc, we presented a reliable synthesis protocol with a highly efficient, organic solvent-free cationic method in GMP con...

Objectives In this study, we aimed to investigate the correlation between SUVmax of primary tumor and prognostic factors/molecular subtype in ductal breast cancer patients. Materials and methods We retrospectively reviewed 150 female patients with pathologically proven invasive ductal breast cancer from January 2015 to October 2019 who underwent ¹...

Objective: Acute appendicitis (AA) is a common urgent surgical situation of the gastrointestinal tract. Gallium-68 (68Ga)-citrate has been recently investigated as a radiopharmaceutical for infection and inflammation imaging. Aim of the study was to determine the effectiveness of 68Ga-citrate positron emission tomography/computed tomography (PET/CT...

Background/aim: The objective of this work was to assess the value of 68Ga-DOTAGA-(3-iodo-y)fk(Sub-KuE) positron emission tomography (68Ga-PSMA-I/T PET-CT) and multiparametric magnetic resonance imaging (mp-MRI) for preoperative staging in prostate cancer (PCa) patients who underwent radical prostatectomy (RP) by validating with postoperative hist...

Positron emission tomography /CT images showed a moderately increased 18F-FDG uptake in the mass of left lung lower lobe superior segment (SUVmax: 2.71). No pathological 18F-FDG involvement was detected in another region of the whole body scan. The patient underwent tru-cut biopsy. Since histopathological diagnosis could not be made, thoracotomy wa...

This study was designed to evaluate the accuracy of detecting pulmonary embolism (PE) using the Technegas SPECT/CT combined with 68Ga PET/CT in a rabbit model. One hour after artificial PE (n = 6) and sham (n = 6) models were created, Technegas SPECT/CT ventilation and 68Ga-MAA PET/CT perfusion scan (V/Q scan) were performed. Ventilation imaging wa...

Background Gallium-68 is an ideal research and hospital-based PET radioisotope. The uptake mechanism of Gallium citrate is a combination of specific and non-specific processes, for example, vasodilatation, increased vascular permeability, plasma transferrin binding and lactoferrin and siderophores. Objective In this study, by applying the ⁶⁸ Ge/ ⁶...

Introduction: In our study, we aimed to investigate the effect of leukocyte incubation temperature, F-18 FDG dose and the use of insulin in the process on leukocyte labeling efficiency. Methods: The study was conducted in the nuclear medicine department of Pamukkale University Medical Faculty between April and October 2019 and is a prospective stud...

Purpose: The aim of this retrospective study is to investigate the efficacy of 18F-FDG PET/CT in detecting primary cancer in patients with cancer of unknown primary and to compare PET/CT results with histopathological results. Materials and Methods: The data of 134 patients who presented to our clinic with the diagnosis of malignancy with unknown p...

18F-FDG PET/CT scanning was performed for the primary staging of a 47-year-old man with urothelial carcinoma. The patient underwent biopsy by ureteroscopy 15 days ago and the PET images revealed 18F-FDG accumulation in the right retroperitenal region, compatible with an “urinoma”.

Abstract Purpose: Although F-18 FDG-labeled leukocyte imaging has not been routinely used in the diagnosis of infection, it has been studied for some time. However, F-18 FDG and leukocyte binding efficiency remains low. In this study, we aimed to determine the effect of insulin and glucagon on leukocyte labeling with F-18 FDG in patients with diagn...

Infectious diseases are the leading cause of death in developing countries. Preclinical studies are carried out with small experimental animals in order to understand the pathophysiology of the infection, to treat it correctly, and to evaluate the effectiveness of the treatment. In these studies, various infection models are created and displayed b...

We assessed the presence and the degree of alteration of the regional blood flow (rCBF) as visualized by Tc-99m HMPAO brain rest SPECT in the sensory motor cortex and subcortical structure in spinal cord injury (SCI) patients, who suffered from various levels of motor and sensory function loss. Twenty-two patients (mean age: 42.1+/-13.4 years, 18 M...

In recent years, it has been possible for patients with Down syndrome to live longer with advanced medical treatment and social support. As a result, the problems of these patients, such as thyroid diseases, leukemia, and Alzheimer disease, would be encountered more frequently. In this study, we aimed to perform the brain perfusion of children with...

Surfactant secreted from type II pneumocytes plays an important role in alveolo-capillary permeability. In thyrotoxicosis, high levels of T3 receptors detected at these cells might affect the alveolo-capillary permeability due to increased serum thyroid hormone levels. The results by CO-diffusion capacity measurement in thyrotoxicosis are conflicti...

We investigated whether spontaneous normalization of negative T waves (TWN) on infarct-related ECG leads (IRLs) in the chronic phase of Q wave anterior myocardial infarction (MI) could be a predictor of residual viability in infarct areas. We prospectively studied 35 patients (age 60 +/- 8.6 years) in the chronic phase of Q wave anterior MI. Sponta...

It has been suggested that low back pain (LBP) may arise from lumbosacral transitional vertebral articulation (LSTVA) itself. It is known that bone scintigraphy is a valuable tool for the recognition of pain arising from bone and articular diseases. Therefore we aimed to show planar and SPECT bone scintigraphic findings of LSTVA and compare them wi...

Tc-99m tin colloid scintigraphy was performed in a 58-year-old man with myelofibrosis to search for extramedullary hematopoiesis (EMH). He had a 14-year history of myelofibrosis, and splenectomy was performed 4 years earlier. He was hospitalized because of a thoracic mass and pulmonary symptoms.

Childhood autism is a developmental disability of unknown origin with probable multiple etiologies. The purpose of this study was to compare the changes of regional cerebral blood flow (rCBF) in autistic and non-autistic controls, and to determine the relationship between rCBF on 99mTc-hexamethylpropylene amine oxime (HMPAO) brain SPECT and the sco...

Fifteen days after giving birth, a 30-year-old woman had the sudden onset of shortness of breath, cough, and paroxysmal nocturnal dyspnea. She underwent Tc-99m DTPA aerosol ventilation and Tc-99m MAA perfusion lung studies within a 24-hour interval. The patient had bilateral venous enlargement of the lower extremities, a history of recurrent pulmon...

Prediction and evaluation of the response to chemotherapy (CTx) are important for the correct and cost-effective treatment of patients with primary lung cancer. Although fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is accepted as the most useful and accurate nuclear medicine technique for this purpose, its expense and limit...