| Two different data formation strategies for HR MSI generation.

| Two different data formation strategies for HR MSI generation.

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A fast and shallow convolutional neural network is proposed for hyperspectral image super-resolution inspired by Spatial-Spectral Reconstruction Network (SSR-NET). The feature extraction ability is improved compared to SSR-NET and other state-of-the-art methods, while the proposed network is also shallow. Numerical experiments show both the visual...

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... best scores are written in bold. We consider two different data formation models for HR MSI (Type 1 and Type 2), which are illustrated in Figure 2. In Type 1, we apply the data formation strategy used in . ...

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(1) Background: Hyperspectral imaging has emerged as a promising margin assessment technique for breast-conserving surgery. However, to be implicated intraoperatively, it should be both fast and capable of yielding high-quality images to provide accurate guidance and decision-making throughout the surgery. As there exists a trade-off between image quality and data acquisition time, higher resolution images come at the cost of longer acquisition times and vice versa. (2) Methods: Therefore, in this study, we introduce a deep learning spatial–spectral reconstruction framework to obtain a high-resolution hyperspectral image from a low-resolution hyperspectral image combined with a high-resolution RGB image as input. (3) Results: Using the framework, we demonstrate the ability to perform a fast data acquisition during surgery while maintaining a high image quality, even in complex scenarios where challenges arise, such as blur due to motion artifacts, dead pixels on the camera sensor, noise from the sensor’s reduced sensitivity at spectral extremities, and specular reflections caused by smooth surface areas of the tissue. (4) Conclusion: This gives the opportunity to facilitate an accurate margin assessment through intraoperative hyperspectral imaging.