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| Representative MR images illustrating 1 H-MRS voxel placement at the medial superior and the anterior inferior parts of the tongue in healthy subjects and their corresponding representative MR spectra measured at TE of 35 ms (A) and TE of 144 ms (B).

| Representative MR images illustrating 1 H-MRS voxel placement at the medial superior and the anterior inferior parts of the tongue in healthy subjects and their corresponding representative MR spectra measured at TE of 35 ms (A) and TE of 144 ms (B).

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FIGURE 1 | Representative MR images illustrating 1 H-MRS voxel...
FIGURE 2 | MR images illustrating 1 H-MRS voxel placement in the...
Evaluation of Proton MR Spectroscopy for the Study of the Tongue Tissue in Healthy Subjects and Patients With Tongue Squamous Cell Carcinoma: Preliminary Findings
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  • Jul 2022
Purpose To noninvasively assess spectroscopic and metabolic profiles of healthy tongue tissue and in an exploratory objective in nontreated and treated patients with tongue squamous cell carcinoma (SCC). Methods Fourteen healthy subjects (HSs), one patient with nontreated tongue SCC (NT-SCC), and two patients with treated tongue SCC (T-SCC) underw...
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Context 1
... healthy subjects-anterior inferior part of the tongue; HS-MS, healthy subjects-medial superior part of the tongue; NT-SCC, patient with nontreated SCC; T-SCC, patient with treated SCC. and 144 ms) performed using a volume voxel of 2 cm 3 × 2 cm 3 × 2 cm 3 . 1 H-MRS voxel was placed at two different locations: the medial superior part (MSP) and the anterior inferior part (AIP) of the tongue for healthy subjects (Figure 1), while it was placed at the most aggressive part of the tumor (based on the appearance of the lesions in pre-and postcontrast-enhanced 3D T1 MRI and T2-weighted imaging with fat saturation). ...
Context 2
... MR images illustrating 1 H-MRS voxel placement at the MSP and the AIP of the tongue in HS are shown on the top of Figures 1, 2. Two corresponding representatives MR spectra obtained from the MSP and the AIP of the tongue in HS are shown at the bottom of Figures 1, 2. ...
Context 3
... MR images illustrating 1 H-MRS voxel placement at the MSP and the AIP of the tongue in HS are shown on the top of Figures 1, 2. Two corresponding representatives MR spectra obtained from the MSP and the AIP of the tongue in HS are shown at the bottom of Figures 1, 2. ...
Context 4
... spectrum obtained from the MSP of the tongue in HS ( Figure 1A) showed a very prominent and large peak (from 1.1 to 1.5 ppm) centered at 1.3 ppm arising from protons in the methylene (CH 2 ) groups of lipids that are attributed to IMCL-CH 2 . A less prominent peak, resulting from protons in the methyl (CH 3 ) groups of lipids corresponding to IMCL-CH 3 , is observed at 0.9 ppm. ...
Context 5
... spectrum obtained from the AIP of the tongue in HS ( Figure 1A) also showed a very prominent and large peak (from 1.1 to 1.5 ppm) centered at 1.3 ppm arising from IMCL-CH 2 that should attributed to IMCL-CH 3 and centered at 0.9 ppm. A weak but larger (compared to the MSP of the tongue) nonassigned peak centered at 2.3 ppm is observed. ...