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[¹⁸F]FSPG images system xc⁻ activity, providing a surrogate marker of glutathione (GSH) biosynthesis. Insert, the structure of [¹⁸F]FSPG.
Source publication
![[¹⁸F]FSPG images system xc⁻ activity, providing a surrogate marker of...](publication/379682130/figure/fig1/AS:11431281236123211@1712984288244/FFSPG-images-system-xc-activity-providing-a-surrogate-marker-of-glutathione-GSH_Q320.jpg)
![[¹⁸F]FSPG maximum intensity projection scans at intervals up to 90 min...](publication/379682130/figure/fig2/AS:11431281236095824@1712984288732/FFSPG-maximum-intensity-projection-scans-at-intervals-up-to-90-min-pi-in-a-subject_Q320.jpg)
![Time–activity curves of normal organ [¹⁸F]FSPG retention (average...](publication/379682130/figure/fig3/AS:11431281236123212@1712984289513/Time-activity-curves-of-normal-organ-FFSPG-retention-average-SUVmax-in-subjects_Q320.jpg)
![Retention of [¹⁸F]FSPG (average SUVmax) in the primary tumor for...](publication/379682130/figure/fig4/AS:11431281236123213@1712984290025/Retention-of-FFSPG-average-SUVmax-in-the-primary-tumor-for-subjects-with-NSCLC-A_Q320.jpg)
![Comparison of [¹⁸F]FSPG PET/CT and [¹⁸F]FDG PET/CT imaging in a subject...](publication/379682130/figure/fig5/AS:11431281236123214@1712984290585/Comparison-of-FFSPG-PET-CT-and-FFDG-PET-CT-imaging-in-a-subject-with-HNSCC-A_Q320.jpg)
Simple Summary
This clinical study explored the use of the positron emission tomography radiotracer, [¹⁸F]FSPG, for cancer imaging. [¹⁸F]FSPG measures a process involved in antioxidant production, which is important for cancer prognosis. We compared the distribution of this imaging agent in subjects with head and neck squamous cell cancer (HNSCC) a...
