18F-Choline PET/MR for whole-body staging of prostate cancer. PET Coronal MIP, high-resolution T2w transverse plane, axial DWI (b = 700), and axial 18F-Choline PET/MR show a nodule in the anterior midgland of the peripheral zone on the right side with restricted diffusion and focal choline uptake suggestive of primary prostatic adenocarcinoma. Additionally, several focal uptakes in the central gland are evinced, corresponding to Benign Prostatic Hyperplasia as observed in axial T2w sequence as an “organized chaos” in the transition zone. A normal-sized left-side deep inguinal lymph node is also depicted, with very faint choline uptake, more likely to be inflammatory. This example shows the synergism of PET and MR to differentiate benign and malignant processes. (This case is a courtesy of Irene Burger, MD from University Hospital of Zurich)