... Several methods for determining ceftazidime in plasma have been used involving ultraviolet (UV) detection (Hanes, Herring, & Wood, 1998;Hassouna & Mohamed, 2018;Isla et al., 2005;Johnson, Vandenbussche, Chio, & Jacobson, 1999;Legrand, Vodovar, Tournier, Khoudour, & Hulin, 2016;Siddiqui et al., 2009;Vinks, Brimicombe, Heijerman, & Bakker, 1997;Yeh et al., 2005). These methods often require larger sample sizes (Isla et al., 2005;Myers & Blumer, 1983;Pinder, Brenner, Swoboda, Weigand, & Hoppe-Tichy, 2017), lack sensitivity (Abdulla, Bahmany, Wijma, van der Nagel, & Koch, 2017;Bellouard et al., 2020;Grabe, Bailie, Eisele, & Frye, 1999;Hanes, Herring, & Wood, 1998;Hassouna & Mohamed, 2018;Isla et al., 2005;Johnson, Vandenbussche, Chio, & Jacobson, 1999;Legrand, Vodovar, Tournier, Khoudour, & Hulin, 2016;Myers & Blumer, 1983;Pinder, Brenner, Swoboda, Weigand, & Hoppe-Tichy, 2017;Rigo-Bonnin et al., 2016;Siddiqui et al., 2009;Vinks, Brimicombe, Heijerman, & Bakker, 1997;Yeh et al., 2005), have complicated extraction methods (Hanes, Herring, & Wood, 1998) et al., 2020;Legrand, Vodovar, Tournier, Khoudour, & Hulin, 2016;Mortensen, Jensen, Zhang, & Doogue, 2019;Rigo-Bonnin et al., 2016;Sillen et al., 2015;Yeh et al., 2005). Siddiqui et al. (2009), Hassouna and Mohamed (2018), Vinks, Brimicombe, Heijerman, and Bakker (1997), Johnson, Vandenbussche, Chio, and Jacobson (1999), Hanes, Herring, andWood (1998), Pinder, Brenner, Swoboda, Weigand, andHoppe-Tichy (2017), Grabe, Bailie, Eisele, and Frye (1999), Myers andBlumer (1983), Isla et al. (2005), Legrand, Vodovar, Tournier, Khoudour, andHulin (2016) andYeh et al. (2005) all utilize UV detection, but their lower limit of quantification (LLOQ), ranging from 0.3 to 500 μg/ml, is greater than that for our method, which is 0.1 μg/ml. ...