Science topics: myalgia
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myalgia - Science topic
Explore the latest publications in myalgia, and find myalgia experts.
Publications related to myalgia (10,000)
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Purpose
Polyarteritis nodosa (PAN) is a systemic vasculitis of unknown etiology affecting medium- and small-sized arteries and can present with varied organ involvement, including ocular manifestations. Here, we report a unique case of PAN that initially presented with diplopia and ocular motility impairment, with subsequent development of bilatera...
In January 2024, all persons with multiple sclerosis (pwMS) treated with natalizumab (NTZ) at Oslo University Hospital switched from originator to biosimilar NTZ. We prospectively monitored 39 pwMS during the first year of treatment with biosimilar NTZ and evaluated change in disease activity, side effects, serum NTZ levels, anti-drug antibodies (A...
Background
With the improvement of living standards, an increasing number of patients are presenting with mixed hyperlipidemia. In addition to cholesterol reduction, it is imperative to lower triglyceride levels. The combination of statin and fibrate for reducing lipid levels has commonly been applied in clinical therapy. However, the combination o...
Introduction. Leptospirosis is endemic to Puerto Rico, affecting people through seasonal increases and outbreaks. This report describes the diagnostic approach and clinical characteristics of leptospirosis cases identified through active undifferentiated acute febrile illness (UAFI) surveillance in Puerto Rico.
Materials and Methods. From 2019-2021...
Three people in England consumed fish steaks labeled as Red Snapper (Lutjanus bohar) originating from the Indian Ocean. Within 12 h, all three experienced sickness including nausea, vomiting, diarrhea, as well as myalgia and paresthesia. Three steaks from a single package of fish obtained from a grocery store were consumed, leaving one un-eaten, wh...
Background/Objectives: Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by muscle weakness and typical cutaneous rash. Dermatomyositis-specific antibodies, such as anti-TIF1γ, anti-SAE, anti-Mi2, anti-MDA5, and anti-NXP2, have been associated with specific clinical phenotypes. Our study aimed to describe the clinical pr...
Background
Arthralgia, myalgia, acute interstitial pneumonia-like presentation, venous thromboembolism, cytopenia, secondary hemophagocytic lymphohistiocytosis and cytokine storm are the clinical and laboratory findings associated with Coronavirus disease (COVID-19), which may mimic rheumatic syndromes. Systemic lupus erythematosus (SLE) is a highl...
Background: The nuclear-encoded enzyme polymerase gamma (Pol-γ) is crucial in the replication of the mitochondrial genome (mtDNA), which in turn is vital for mitochondria and hence numerous metabolic processes and energy production in eukaryotic cells. Variants in the POLG gene, which encodes the catalytic subunit of Pol-γ, can significantly impair...
We compared neuromuscular fatigue induced by cycling at a fixed perceived effort in normoxic condition (NOR) and three purported hypoxia modalities: systemic hypoxia (SyH, FiO2 = 0.13), blood flow restriction (BFR, 50% arterial occlusion pressure) and airflow restriction mask (ARM, calibrated to ~3500 m). Seventeen healthy young participants cycled...
Lazertinib is a third‐generation epidermal growth factor receptor tyrosine kinase inhibitor effective in patients with non‐small cell lung cancer. Although generally well tolerated, this case report presents a rare occurrence of common terminology criteria for adverse events grade 3 rhabdomyolysis in a 69‐year‐old Korean woman after taking lazertin...
Background
Long COVID is characterized by persistent symptoms affecting one or more organ systems for at least 3 months following a SARS-CoV-2 infection. The pathophysiologic mechanisms of this complex disease are poorly understood. Beyond the described symptoms of fatigue, dyspnea, myalgias, among others, Long COVID can affect the patient’s abilit...
Background
The effectiveness and practicality of blood flow restriction training (BFRT) as a nonsurgical intervention for treating patients with knee injuries are uncertain because of the small size of BFRT trials and inconsistent results.
Purpose
To conduct a meta-analysis comparing the effectiveness of BFRT versus traditional resistance training...
OBJECTIVE: To investigate the clinical characteristics, laboratory findings, and risk factors associated with COVID-19 mortality among elderly patients in Khoy, West Azerbaijan, Iran. METHODOLOGY: This retrospective cross-sectional study analyzed data from 447 confirmed COVID-19 patients over 60 years old hospitalized in Khoy's referral hospital be...
Introduction
The aim of this systematic review of prevalence is to observe and discuss the clinical manifestations of Chikungunya Virus disease in its chronic phase.
Methods
To be eligible, the observational studies should accompany the individuals for at least six months. The research was conducted using electronic databases MEDLINE and EMBASE. T...
In COVID-19, long term intake of Antivirals, Antibiotics, Antimicrobials, Corticosteroids and ventilator exposure leads to ill effect in individual. Such as Fatigue, Weight loss, Weakness, Intermittent raise in Temperature, Headaches, Myalgias etc. are signs and symptoms noted in after effect of COVID-19. It is necessary to combat Post-covid signs...
The study examined how carbohydrate-protein (CHO-PROT) beverages affect anaerobic capacity after exercise. Fifteen male university football players, aged 20–25, participated in a 90-minute cycling session while consuming one of three drinks: CHO-PROT, carbohydrate-only (CHO), or a placebo (PLA). Results analyzed with two-way repeated measures ANOVA...
This study aimed to investigate the side effects observed in healthcare personnel who were the first to receive the first dose of inactivated CoronaVac® vaccine in Turkey. Healthcare personnel vaccinated for the first time with the inactivated CoronaVac® vaccine between February and March 2021 during the initial administration of COVID-19 vaccines...
Acute pyrexia patients suspected of Scrub typhus tested positive for IgM Scrub typhus Elisa. Gender distribution was not significant, with males (72.7%) being the majority of positives. Age groups 0-10 years have the highest IgM 7/17 seropositive rates (41.2%), with majority patients aged 21-30. Males, particularly in rural areas, are engaged in ou...
Measuring exercise intensity for safety and to inform prescription in acute burn survivors, is challenging. This study aimed to assess the validity of adult patient end-of-workout rating of session perceived exertion (sRPE); and calculated training load (TL) (sRPE × session duration) as measures of exercise intensity. Secondly, the study aimed to c...
Objectives
Temporomandibular disorder (TMD) encompasses various clinical issues affecting the temporomandibular joint, masticatory muscles, and surrounding structures. Common symptoms include pain, joint and muscle tenderness, and limited jaw movement. Diverse treatment options have been utilized to manage TMD. However, evidence of the combined mod...
Background
During the 2023-dengue outbreak in Bangladesh, a diagnostic evaluation study was conducted to investigate concurrent Zika virus (ZIKV) and dengue virus (DENV) transmission in Dhaka in 2023.
Aims
The study explored to simultaneously detect the presence of ZIKV, DENV, and/or CHIKV while considering relevant clinical and epidemiological ri...
Introduction: Chronic hepatitis C virus (HCV) infection is important
cause for cirrhosis of liver all over the world and many patients
suffering from this deadly disease require liver transplantation as the
definitive treatment. The oral directly acting antiviral for treatment has
changed management of its treatment in a significant way, as these
d...
Background
Dengue is the fastest spreading mosquito-borne viral infection, which affects people living in the tropical and subtropical countries and cause severe clinical symptoms and possibly death. We aimed to determine the epidemiological and clinical characteristics of patients with dengue fever and to find mortality predictors.
Methods
We con...
The H1N1 influenza strain originated in Mexico and the Southwestern United States in March of 2009 and was caused by a new variant of influenza A virus. Some studies have revealed that renal and liver damage can occur in rare cases of influenza H1N1 virus. Acute liver failure in H1N1 virus is one of the lesser-known pathologies. However, despite de...
Objective To investigate the respiratory signs observed in individuals hospitalized due to dengue infection. Methods This observational study encompassed a cohort of 50 individuals diagnosed with dengue fever, as confirmed by the presence of NS1 antigen, who were hospitalized to Shaheed Captain Mansur Ali Medical College Hospital in Uttara, Dhaka,...
Cycling challenges athletes to their physiological and psychological limits, often culminating in task failure: an abrupt reduction in intensity or cessation of effort. While physiological mechanisms such as metabolic acidosis and oxygen supply have been widely studied, less is known about the subjective experience associated with task failure. In...
Introduction: This review paper aims to verify the safety of monacolin K, examine the effect on blood cholesterol levels, discuss the contribution to the reduction of cardiovascular risk and indicate examples of pleiotropic effects of this substance. Materials and methods: A review of chosen literature in the PubMed database was conducted, using th...
Objective
To characterize the clinical manifestations of yellow fever disease and identify risk factors for mortality.
Methods
A retrospective study was conducted in the referral center for infectious diseases (Hospital Eduardo de Menezes-HEM) in Belo Horizonte, Minas Gerais, Brazil. Analysis included data from 283 patients with confirmed YF infec...
Background: Sleep quality plays a crucial role in maintaining overall health and functional ability, particularly in individuals with chronic spinal cord injury (SCI). Sleep disturbances are highly prevalent in this population due to neuropathic pain, muscle spasticity, autonomic dysfunction, and psychological distress. Poor sleep can negatively im...
Crimean–Congo hemorrhagic fever (CCHF) is fatal in 10 to 40% of cases. It is caused by CCHF virus (CCHFV). Symptoms include fever, headache, myalgia, and often hemorrhage and other complications. This report shows that CCHF may resemble HELLP syndrome (hemolysis, elevated liver enzymes, low platelets). We report CCHF in a pregnant mother with fever...
The present study investigated the clinical and hematological effects of chronic lead exposure in the population residing in Shadi Pura, a small industrial zone in Lahore, Pakistan. A cross-sectional analysis of 149 participants recruited through health camps was conducted to explore the hematological manifestations of environmental lead exposure,...
The aim of this study was to analyze the effects of the playing position (backs vs. pivots vs. wings) and the player role (starter vs. non-starter) on the internal match load and well-being status of female handball players after official matches. Fourteen female handball players from the Spanish 2nd Division were monitored during a half-season (13...
Bromelain, an enzyme gotten from pineapples has stirred interest for its ability to reduce muscular pains and slow down delayed onset muscles soreness (DOMS) which occurs after working out or while having exercising routines among athletes and physically active individuals. The purpose of this study was to assess the efficacy of bromelain in attenu...
Monkeypox (MPX) is a zoonotic disease, caused by the MPX virus. Clinical symptoms and signs of the disease are similar to, but less severe than, smallpox, presenting with fever, headache, lymphadenopathy, back pain, myalgia, and skin rash. MPX can affect the central nervous system causing different complications, including encephalitis, cerebral ed...
Moringa oleifera leaves has potential as a natural tenderizing agent for goat meat, explicitly targeting the longissimus muscle. The study aimed to improve goat meat tenderization by using Moringa Oleifera and provide an eco-friendly and health-conscious method for improving the quality of goat meat. Treatments with fresh moringa leaves (as paste 1...
The incidence of dengue fever is rising annually due to changing lifestyles, dietary habits, and rapid urbanization with poor sanitation. It is increasingly prevalent in developing countries, and no known modern medicine effectively increases platelet count in dengue. Guduchi Kwath improves platelet count, lowers fever, relieves maculopapular rash,...
Background
Covid-19 is a pandemic viral disease that directly or indirectly affects multiple organ systems, including the cardiovascular system. SPECT GATED MPI is a non-invasive nuclear imaging modality used to assess myocardial perfusion and function. The aim of this study was to evaluate the effect of Covid-19 pandemic on myocardial perfusion im...
Chikungunya is an RNA virus transmitted through mosquito bites, leading to symptoms such as fever, joint swelling, discomfort, and muscle soreness. This article proposes a surface plasmon resonance (SPR)-based biosensor for chikungunya virus detection, utilizing the Kretschmann configuration. The sensor’s structure includes a BK7 prism, silver (Ag)...
Objective: This study examined the effects of two recovery techniques, combined techniques and passive recovery, on physiological, neuromuscular, and psychophysiological performance in competitive squash players during three days of simulated matches. Methodology: Eleven elite squash players (age: 15 ± 5 years; height: 172.80 ± 8 cm; body mass: 65....
Skeletal muscle shear elastic modulus is a non-invasive surrogate for early detection of muscle damage and soreness consequent to unaccustomed eccentric muscle work. We investigated the influence of marathon distance running on skeletal muscle shear elastic modulus. Shear modulus of the rectus femoris was measured via ultrasound shear wave elastogr...
Introduction: Mechanical stress and inflammation contribute to exercise-induced muscle damage. Objective: This research analyzed the potential of polyphenolic compounds in grapes to prevent inflammation and lower oxidative stress after exercise. Methodology: This research employed a systematic review to guide the researchers in achieving the object...
Citation: Benedetti, L.; Nigro, F.; Malaguti, M.; Di Michele, R.; Angeloni, C. Acute Effects of Dark Chocolate on Physical Performance in Young Elite Soccer Players: A Pilot Study. Appl. Sci. 2025, 15, 965. https://doi. Abstract: Background: Dark chocolate is rich in polyphenols and has been linked to cardiovascular and metabolic benefits. Its pote...
Background: There are ongoing controversies regarding pregnancy outcomes during the COVID-19 era.
Objectives: This observational study with a retrospective design was conducted to investigate the maternal and neonatal
impacts of COVID-19 on pregnancy outcomes.
Methods: An observational study with a retrospective design was carried out using census...
Background
Aromatase inhibitors (AI) reduce hormone receptor-positive breast cancer recurrence risk by about 50%. However, half of AI-treated postmenopausal women report new or worsened musculoskeletal symptoms (AIMSS), and 20% discontinue therapy prematurely. Acupuncture is effective for reducing symptoms, but many women are not able to access acu...
Background
Cardiovascular, respiratory, and musculoskeletal disease are among the leading causes of disability in middle-aged and older people. Health and lifestyle factors in youth have known associations with cardiovascular or respiratory disease in adulthood, but largely unknown associations with musculoskeletal disease.
Methods and findings
We...
Background and Objectives: Chronic low back pain is a widespread condition, particularly in older populations, contributing to physical, mental, and social burdens. Traditional treatments, such as medications and surgery, carry long-term risks, including dependency, side-effects, and complications from invasive procedures. Additionally, healthcare...
Since clinical features of chronic muscle pain originating from the low back and limbs are different (higher prevalence and broader/duller sensation of low back muscle pain than limb muscle pain), spinal and/or supraspinal projection of nociceptive information could differ between the two muscles. We tested this hypothesis using c-Fos immunohistoch...
Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed to describe the safety of two doses of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared to immunocompe...
Background
Hypermobility is the capacity to perform joint movements in amplitudes greater than normal. Hypermobility is present in nearly 100 % of congenital myopathy central core disease (CCD) patients but is sporadically described in the allelic disease malignant hyperthermia (MH). Our objective was to investigate the frequency/characteristics of...
Training load is defined as an activity that causes stress on the athlete's body during the execution of a task to provide improvement in the sports form. In computers there is Excel®, with this tool the trainer can program to calculate the training load and it is easy to use. The objective of the narrative review was to teach how to use the Excel®...
Aim
The aim of the study was to survey the observed incidence of adverse effects (AEs) related to electroconvulsive therapy (ECT) in Finnish neuromodulation units, as well as to explore what medical interventions are used to prevent and treat them in those units.
Methods
An electronic survey was conducted among Finnish neuromodulation units at the...
Abstract: Background/Objectives: Chronic kidney disease (CKD) is a severe health problem with dire consequences for the quality of life of millions of individuals and their families around the globe. This quantitative study analyzes the factors associated with hemodialysis patients' quality of life (QoL) in Lahore City, Pakistan. Methods: Primary d...
Caffeine is one of the most widely consumed and studied stimulants worldwide with a long history in athletics as a performance enhancer. Although listed as a stimulant in the World Anti-Doping Agency’s (WADA’s) 2024 Monitoring Program, its use is not prohibited. Individual responses to caffeine vary widely due to factors like genetics, age, and lif...
Brodalumab, a humanized monoclonal antibody that targets the interleukin-17 receptor A, is primarily used to manage moderate-to-severe plaque psoriasis. Although it has demonstrated favorable efficacy and safety in clinical trials, the strict inclusion and exclusion criteria may not fully reflect its safety profile in real-world settings. As its us...
Background and Aims
Dengue is a mosquito‐borne viral disease that frequently causes seasonal outbreaks in Bangladesh, particularly during the monsoon months from June to September. Recent outbreaks have shown significant shifts in clinical manifestations, including changes in the timeframe and serotype mixing. This study focused on the clinical and...
Previous studies on the effects of intensified training on sleep quality/quantity have been somewhat contradictory. Moreover, recreational athletes often track various sleep metrics, and those metrics’ actual connections to training adaptations are unknown. This study explored the effects of intensified training on sleep and nightly recovery along...
Globally distributed, systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can impact any organ or tissue. It is a global illness that primarily affects women in childbearing age groups. The female to male ratio of 13:1 indicates that women experience a higher incidence rate of SLE than men do. SLE can be brought on by a number o...
The aim of this study was to examine the effect of breathing a hyperoxic gas mixture on recovery kinetics after a simulated soccer match protocol. In a double-blind, randomized design, twenty-eight semiprofessional soccer players completed the Loughborough Intermittent Shuttle Test (LIST) followed by the administration of either a hyperoxic (FIO2 =...
Background
COVID-19 disease results in disparate responses between individuals and has led to the emergence of long coronavirus disease (Long-COVID), characterised by persistent and cyclical symptomology. To understand the complexity of Long-COVID, the importance of symptom surveillance and prospective longitudinal studies is evident.
Methods
A 9-...
Introduction
This study was designed to determine the prevalence of myofascial pain and the location of myofascial trigger points (MTPs) in dogs with osteoarthritis.
Methods
Thirty-five dogs were selected and examined for the presence of MTPs using palpation. Assessments were performed independently by two examiners. Correlations between age, MTP...
Objectives
Granulomatous myositis (GM) is a rare entity whose precise clinical features and therapeutic outcomes have not yet been well defined. Given the limited evidence, data from a large cohort of patients is needed to aid in the recognition and management of this condition.
Methods
We retrospectively analyzed our institutional databases to id...
Objective
The prevalence of long COVID among cancer patients remains unknown. This study aimed to determine the prevalence of long COVID and explore potential risk factors among cancer patients.
Methods
A systematic search was performed on PubMed, Web of Science, and Embase from database inception until 21 March 2024, to identify studies that repo...
Unani System of Medicine takes entire constitution of the individual and lifestyle into account for prescribing treatment. It provides radical and safe cure for various chronic and lifestyle disorders. USM incorporates ´Ilāj bi’l Tadbīr (Regimenal therapy) as a treatment plan as well as the modification in Asbāb Sitta Ḍarūriyya (six essential facto...
Background and Goal: High-level football players’ competitive performance and training efficacy are significantly impacted by sports weariness. Verifying the possible use of external sodium bicarbonate lotion in professional sports and investigating its effects on the training effect and sports fatigue of elite football players following high-inten...