Science topic

Wounds - Science topic

A wound is a type of injury in which skin is torn, cut, or punctured (an open wound), or where blunt force trauma causes a contusion (a closed wound). In pathology, it specifically refers to a sharp injury which damages the dermis of the skin.
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Publications related to Wounds (10,000)
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The high demand for rapid wound healing has spurred the development of multifunctional and smart bioadhesives with strong bioadhesion, antibacterial effect, real-time sensing, wireless communication, and on-demand treatment capabilities. Bioadhesives with bio-inspired structures and chemicals have shown unprecedented adhesion strengths, as well as...
Article
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Wound healing is one of the major global health concerns in patients with diabetes. Overactivation of pro-inflammatory M1 macrophages is associated with delayed wound healing in diabetes. miR-29ab1 plays a critical role in diabetes-related macrophage inflammation. Hence, inhibition of inflammation and regulation of miR-29 expression have been impli...
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Poor wound healing is considered an obstacle in diabetics, which requires effective therapy. Our goal was to investigate the combined effect of mint and silver nanoparticle hydrogel films as wound-healing agents in diabetic rats. Thirty rats were arranged into five groups. The hydrogel films were prepared through an eco-friendly method, excluding t...
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The complex process of wound healing depends on the coordinated interaction between various immunological and biological systems, which can be aided by technology. This present review provides a broad overview of the medical applications of piezoelectric and triboelectric nanogenerators, focusing on their role in the development of wound healing te...
Article
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We report the case of a patient who underwent transcatheter aortic valve implantation via left anterior mini-thoracotomy in whom a periapical subcutaneous collection appeared in the anterior thoracic wall 18 months after the procedure. The tissue defect was efficaciously repaired via intercostal artery perforator flap, preserving the thoracodorsal...
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We report 4 cases of extremity reconstruction using Bilayer Wound Matrix with plan to perform two-stage procedures. Patient preference or non-compliance led to single-stage reconstruction with wound re-epithelialization. In this setting, dermal matrices may be used as single-stage stand alone wound reconstruction procedures, even in patients with c...
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The radial artery supplies various locoregional flaps used for elbow reconstruction. A reverse lateral arm flap is a reliable choice, despite sacrificing the radial artery in some cases. We describe using a reverse lateral arm flap for elbow soft tissue reconstruction in a patient with a previously harvested radial artery.
Article
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We report 3 cases of patients treated with Bilayer Wound Matrix over exposed structures. In all patients, dermal matrices revascularization occurred sequentially over the course of 6–12 weeks, leading to successful wound closure. Acellular dermal matrices allow more difficult areas with poor vascularity to be covered from the ‘inside-out’.
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Background Flap reconstruction with perforator, fasciocutaneous, muscular, and/or free microvascular flaps is utilized to cover wound defects and improve vascularization and antibiotic/nutrient delivery. Flap use in revision procedures for total knee arthroplasty has been explored previously; however, current data are limited and studies comparing...
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Introduction Posterior hip dislocation is the commonest type of hip dislocation. It is associated with femoral head fracture in 7% of cases. Urgent and congruent hip reduction is mandatory to improve clinical outcomes and avoid irreversible complications. The purpose of this study is to assess the safety and functional and radiological outcomes of...
Article
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Purpose This systematic review and meta-analysis aimed to study surgical site infection of wound closure using staples versus sutures in elective knee and hip arthroplasties. Methods A systematic literature review was performed to search for randomized controlled trials that compared surgical site infection after wound closure using staples versus...
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The contribution of energised environmental debris to injury patterns of the blast casualty is not known. The extent to which personal protective equipment (PPE) limits the injuries sustained by energised environmental debris following an explosive event is also not known. In this study, a cadaveric model exposed to a gas-gun mediated sand blast wa...
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A new technique was used to measure the viscoelasticity of in vivo Pseudomonas aeruginosa biofilms. This was done through ex vivo microrheology measurements of in vivo biofilms excised from mouse wound beds. To our knowledge, this is the first time that the mechanics of in vivo biofilms have been measured. In vivo results are then compared to typic...
Article
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Background The proper decompression for hemicraniectomy depends on intraoperative surgical technique, so the skin incision, on the other hand, is an important variable throughout hemicraniectomy, and there are a variety of cutaneous incisions, including the Kempe T shaped, the reversed question mark and the retro-auricular incisions. We aim to comp...
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Patients with diabetes mellitus may experience peripheral neuropathy and extremity system impairment, which may lead to ulceration if the treatments are delayed. Diabetic ulcers, unfortunately, are chronic, which require proper treatments, including debridement and bacterial removal using an irrigation device. To date, commercial irrigation dev...
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Undermining is thought to improve wound outcomes; however, randomized controlled data regarding its efficacy are lacking in humans. The objective of this randomized clinical trial was to determine whether undermining low to moderate tension wounds improves scar cosmesis compared to wound closure without undermining. Fifty-four patients, 18 years or...
Article
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This article focuses on analytic solutions for Newtonian fluid flow with slip and mass transpiration on a porous stretching sheet using the differential transform method and Pade approximants of an exceptionally nonlinear differential equation. The impacts of different parameters including mass transpiration (suction/injection), Navier's slip, and...
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Appendicectomy is a common pediatric surgical procedure performed by trainees and surgeons with varying reported outcomes. It is a benchmark procedure for trainee progression and training benefits should be weighed against patient safety and perioperative outcomes. This systematic review and meta-analysis investigated any differential perioperative...
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OBJECTIVES: Digital injuries are among the most common presentations to the emergency department. In order to sufficiently examine and manage these injuries, adequate, prompt, and predictable anesthesia is essential. In this trial, we aim to primarily compare the degree of pain and anesthesia onset time between the two-injection dorsal block techni...
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Although leopards are found worldwide, the incidence of leopard attack on humans is reported most often from India and Nepal. Usually, leopards avoid contact with people, but humans may occasionally be targeted as prey. Animal bite wounds may express as punctures, abrasions, tears, or avulsions. The force and bluntness of the teeth increase the pro...
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Background Airborne transmission diseases can transfer long and short distances via sneezing, coughing, and breathing. These airborne repertory particles can convert to aerosol particles and travel with airflow. During the Coronavirus disease 2019 (COVID-19) pandemic, many surgeries have been delayed, increasing the demand for establishing a clean...
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Background The Sheng-ji Hua-yu (SJHY) formula is a quite effective Traditional Chinese Medicines (TCM) in the treatment of delayed diabetic wounds. Previous research has shown that the SJHY formula has significant anti-inflammatory and wound-healing effects, but the precise mechanism remains unknown. The purpose of this study was to evaluate the ef...
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Background: Intussusception in older children may be less common than intussusception in infants. However, it is a significant cause of bowel obstruction across all age groups. The aim of this study was to evaluate our experience with regards to older children (5 years and above) who were managed for intussusception in a single tertiary center in a...
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Epidermal growth factor (EGF) is a highly effective stimulator which promotes cell proliferation and this has led it to being proposed as a prospective healing agent for various treatments of wounds and many other clinical applications. With such a high demand for this protein, it is therefore important to firstly develop an expression system that...
Article
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Travel Medicine is one branch of medicine which specializes in preventing and treating medical problems for travelers especially when they are traveling. It is undeniable that there are differences in medical knowledge between developing and developed countries when dealing with traveler’s health problems. The purpose of this study is to comprehend...
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Introduction Abdominal wall reconstruction (AWR) in a contaminated field is associated with an increased risk of wound complications, infection, and reoperation. The best method of repair and mesh choice in these operations have generated marked controversy. Our aim was to compare outcomes of patients who underwent AWR with biologic versus syntheti...
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Bacterial infections of wounds significantly increase the occurrence of complications, which have become a public health problem and pose a serious threat to human health. Therefore, an ideal wound dressing should not only possess suitable mechanical strength and a moist environment, but also instant disinfection and antibacterial properties. Owing...
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Background Malignancies that spread to the lymph nodes may be identified through surgical biopsy, and treatment of metastatic disease may be through lymph node dissection. These surgeries, however, may be associated with significant adverse outcomes, particularly wound complications, the true incidence of which remains unknown. Multiple studies hav...
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Background: When bodies are lynched, there could be loss of body parts, deep wounds, bruises and fractures of the bone which would lead to difficulties in embalming processes. There is little or no literature on the embalming of early decomposing lynched bodies in Nigeria. Objective: This study investigated the effectiveness of an embalming mixtur...
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Purpose To determine if the type of approach used for treatment of lateral split-depression tibial plateau fractures affects clinical outcome and complications rate. Methods This is a retrospective review of 169 patients who presented between 01/2005 and 12/2020 to a Level-I trauma center for operative management of an isolated lateral Schatzker I...
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Introduction Subgaleal drainage is often being used in craniotomy procedures. It's not only offers advantages but also carries a risk of life-threatening complications. Here, we present a rare case of subgaleal hematoma and skin necrosis caused by placement of subgaleal drainage in a pediatric patient after a craniotomy procedure. Case report We r...
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Although the simple diffusion model can effectively describe the movement of eukaryotic cells on a culture surface observed at relatively low sampling frequency, at higher sampling rates more complex models are often necessary to better fit the experimental data. Currently available models can describe motion paths by involving additional parameter...
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Shark attack-related injuries (SARIs) are rare but may result in highly complex wounds requiring reconstruction by plastic surgeons. Here, we present an unusual case of SARI of the breast and briefly review literature on reconstructive management of (1) breast injuries from other large animals and (2) SARIs to other parts of the body. Our patient w...
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Background Transanal minimally invasive surgery (TAMIS) is technically demanding and requires extensive training. We developed the TAMIS simulator model by remodeling an existing laparoscopic training system to educate trainees and analyzed their learning curves. Methods Between March 2020 and June 2020, 12 trainees performed TAMIS simulator train...
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Deep sternal wound infection and dehiscence has been classified as complex wound, and its treatment is a challenge for the surgeon. There are many flap choices for its treatment, each one having advantages and drawbacks. The article by Wang et al. evidenced that the unilateral pectoralis major muscle flap is a simple and effective option for wound...
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The aim of this article is to evaluate the definition of the term "The Wound-(Al-Jořh)" in the Jordanian Penal Law by finding out the linguistic meaning of the term and its idiomatic meaning in forensic medicine by taking into account the term definition within the Penal Law added for the term "The wound". Depending on the descriptive-analytical me...
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An 85‐year‐old male developed a hematoma over his radial artery harvest scar 6 weeks after coronary artery bypass grafting. This occurred immediately after his blood pressure was checked using a digital blood pressure monitor with the cuff applied to his left arm. The swelling resolved over the next 5 months. We recommend that patients who have und...
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This report describes the first documented incident of a possible shark predation on an Irrawaddy dolphin (Orcaella brevirostris) in the Philippines. The incident happened in Guimaras Strait, one of the four known habitats of Irrawaddy dolphins in the country. We list three possible shark species that may have attacked the dolphin: great white shar...
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Cranial cerebrospinal fluid (CSF) leak is an extremely rare complication of blunt head trauma causing skull fractures, especially fractures involving the skull base. We present the case of a 10-month-old male who received glass fragments on the midline and posterior tier of his anterior fontanelle producing a cranial cerebrospinal fluid leak withou...
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Background The proper approach to repair of complex abdominal wall hernia in contaminated and dirty surgical fields is unknown. Identification of a surgical approach limiting the number of operative procedures, post-operative complications, and financial burden is needed. We hypothesized that single-stage abdominal wall reconstruction using poly-4-...
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The 2022 war in Ukraine has highlighted the unacceptable consequences wrought on civilians and health infrastructure by conflict. Children are among the most vulnerable of those affected and constitute an increasing percentage of non-combatants injured in conflicts globally. A disproportionate number of these injuries are caused by blast mechanisms...
Article
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This article aims to identify the profile of police officers who underwent surgery due to gunshot wounds to the face, to survey the anatomical distribution of injuries and the repercussions on their health, work and family relationships. We conducted a retrospective epidemiological study based on secondary data of police officers who underwent surg...
Article
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PurposeDespite the limited research in support of robotic inguinal hernia repair (RIHR), it is an increasingly adopted technique in surgical practice. While a major risk factor for the development of ventral hernias and subsequent complications, obesity in RIHR has not been investigated. The aim of this study was to compare the outcomes of RIHR bet...
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Background It is rare to find pseudoepitheliomatous hyperplasia (PEH) on the auricle. PEH should be differentiated from squamous cell carcinoma (SCC). Diagnosis is made after surgery as a biopsy is often inconclusive. A free or pedicled skin flap is needed to avoid deformation of the auricle. Methods Adjacent pedicled skin flap is a good option fo...
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A growing emphasis is being placed on raising global awareness of the magnitude and consequences of work-related accidents, injuries, and diseases, as well as designing and implementing efficient preventive and protective policies and programs. Statistical data on occupational accidents and diseases, as well as work-related deaths on a national lev...
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Background Closure of the deep sternal wound is a well-known challenge for chest and plastic surgeons. Various techniques have been described. However, there remains a need for a better one—a simple, safe procedure with minimal complications for patients, who usually present with underlying serious comorbidities. We present our technique for medium...
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NADPH oxidase (Nox) complexes are known to play essential roles in differentiation and proliferation of many filamentous fungi. However, the functions of Noxs have not been elucidated in Colletotrichum species. Therefore, we set out to characterize the roles of Nox enzymes and their regulators in Colletotrichum scovillei, which causes serious anthr...
Article
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This article aims to identify the profile of police officers who underwent surgery due to gunshot wounds to the face, to survey the anatomical distribution of injuries and the repercussions on their health, work and family relationships. We conducted a retrospective epidemiological study based on secondary data of police officers who underwent surg...
Article
Full-text available
Background: Forearm fractures are one of the most common fractures in children. Over the last years, a tendency towards surgical treatment was seen, especially closed reduction and internal fixation with elastic stable internal nailing (ESIN). Despite an overall low complication rate being described, a risk of intraoperative complications remains....
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Medical and pathology records were reviewed for 161 Critically Endangered Livingstone's fruit bats Pteropus livingstonii (LFBs) held at Jersey Zoo and Bristol Zoological Gardens between 1992 and 2017, representing over 95% of the historical population managed at these institutions. The association of mortality and morbidity in relation to age (imma...
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In this article we engage with four experimental ethnographies (Blaser, 2010; Lyons, 2020; Miller, 2019; and Gordillo 2014) that build on multispecies approaches for the analysis of what we call ‘wounded relational worlds’ in Latin America. These are worlds in which human and more-than-human relations have been significantly reshaped, broken, or di...
Article
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Laparoscopic surgery is undergoing rapid development. Replacing the traditional method of joining cut tissues with sutures or staples could greatly simplify and speed up laparoscopic procedures. This alternative could undoubtedly be adhesives. For decades, scientists have been working on a material to bond tissues together to create the best possib...
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Abstract Introduction: Blood exposure accidents (BEA) are a major public health problem, especially in developing countries such as Cameroon. Evaluating the knowledge and practices among healthcare workers (HCWs) of the Ngaoundere Regional Hospital (NRH), in relation to BEA, was a logical step towards addressing this concern in Cameroon. Design: Fr...
Conference Paper
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One in three people with diabetes develops diabetic foot ulcers (DFUs) during their lifetime, which is a major risk factor for amputation and mortality. Optical imaging techniques have been developed to determine the extent of oxygenation to these DFUs, which is vital to assessing DFU wounds. Herein, a machine learning approach was implemented to l...
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zet Yüzeyaltı borulu drenaj sistemlerinde borularda siltasyonu ve tıkanmaları önlemek için, değişik filtre ve zarf materyalleri üretilmiştir. Bunlar, organik ve inorganik materyaller, hazır kaba sarımlı materyaller, jeotekstiller, sentetik ve organik liflerdir. Drenaj sistemlerinde yaygın olarak kullanılan granüle materyallerin birörnek olmaması ve...
Article
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Objective. To research the application of CTU-assisted Doppler ultrasound puncture in uncatheterized PCNL, its influence on patients’ complications, and its clinical value in a case-control study. Methods. One hundred and forty-four patients who went through percutaneous nephrolithotomy (PCNL) from March 2019 to June 2021 in our hospital were arbit...