Weight Loss - Science topic

Thanks for sharing the resolution so we all can learn.

Not sure if this study below is useful? I've been "collecting" papers on insulin resistance

Bantle, A. E., Lau, K. J., Wang, Q., Malaeb, S., Harindhanavudhi, T., Manoogian, E. N. C., Panda, S., Mashek, D. G., & Chow, L. S. (2023). Time‐restricted eating did not alter insulin sensitivity or β‐cell function in adults with obesity: A randomized pilot study. Obesity (Silver Spring, Md.), 31(1), 108–115. https://doi.org/10.1002/oby.23620

What I am finding is that often overlooked in obesity/insulin resistance is conditions like Lipoedema which often co-occurs with Hypermobility and neurodivergence. If Lipoedema is studied, they often don't control for hypermobility or neurodivergence and us ADHD folks do like to stay up later...

Zechner, U., Kohlschmidt, N., Kempf, O., Gebauer, K., Haug, K., Engels, H., Haaf, T., & Bartsch, O. (2009). Familial Sotos syndrome caused by a novel missense mutation, C2175S, in NSD1 and associated with normal intelligence, insulin dependent diabetes, bronchial asthma, and lipedema. European Journal of Medical Genetics, 52(5), 306–310. https://doi.org/10.1016/j.ejmg.2009.06.001

Lundanes, J., Storliløkken, G. E., Solem, M. S., Dankel, S. N., Tangvik, R. J., Ødegård, R., Holst, J. J., Rehfeld, J. F., Martins, C., & Nymo, S. (2025). Gastrointestinal hormones and subjective ratings of appetite after low-carbohydrate vs low-fat low-energy diets in females with lipedema – A randomized controlled trial. Clinical Nutrition ESPEN, 65, 16–24. https://doi.org/10.1016/j.clnesp.2024.11.018

Dear Shofia Khoirunnisa,

You are absolutely right. The initial weight of the sample should be set to 100 wt%. The TGA of Cu-MOF indicates a weight of 34% at the start temperature (50 degrees Celsius), suggesting an issue with the thermogravimetry instrument. It is advisable to calibrate the TG instrument before recording the thermogram of your sample.

could you reformulate the question with more information of your objetive?

Best

To compare weight-loss outcomes between the four medication groups for the entire duration of the study (four years), you can use a one-way ANOVA. Here's how you can do it:

Dear friend Rosa María Huertas Penela

Based on the DSC and TGA analyses you've Rosa María Huertas Penela provided for ZIF-8 samples, it appears that there is potential for desorption of gases and water within the temperature range of 30ºC to 60ºC. The endothermic peak observed around 50ºC in the DSC analysis and the weight loss in TGA between 38ºC and 125ºC indicate that there might be gas and water molecules trapped within the ZIF-8 structure.

Given this data, desorption could indeed occur within the specified temperature range. However, it's essential to consider the specific application and the desired level of desorption. If complete desorption is necessary, additional techniques or higher temperatures may be required.

In terms of suggestions for another process, I would recommend exploring techniques such as thermal cycling or vacuum treatment to enhance desorption efficiency. These methods could complement the temperature range you've mentioned and help achieve the desired level of gas and water removal from the ZIF-8 structure.

Overall, based on the provided data, desorption of CO2, N2, or water in ZIF-8 between 30ºC and 60ºC seems feasible, but further optimization and experimentation may be needed to achieve optimal results for your Rosa María Huertas Penela specific application.

Your background in dentistry should place you in a technically positive position to understand our clinical position. We have documented mandible and maxilla marrow cavity infections that, with training in reading orthopantomogram x-rays, can identify these infections. These infections drain through the gingiva and present as 'chronic' gingivitis. With every pressure on the structure discharge enters the saliva and sets up a foundation for digestive fermentation.

To correct Diabetes and other metabolic disorders syndrome Please go to the link and read the book

For English https://www.lulu.com/shop/innovator-pramod-stephen-and-dr-prem-prakash-stephen/your-health-is-in-your-mouth/ebook/product-m8d9mk.html?page=1&pageSize=4

मधुमेह और अन्य उपापचय की असमान्य क्रिया को ठीक करने हेतु पढे:-

For Hindi https://www.flipkart.com/aapka-swasth-aapke-muh-me/p/itm22edae101e74a?pid=9789393385543

I recommend to use a bar graph as this type of schematic is very easy for the reader to understand.

We have the animal house. We hope to work together.

If you add acid or alkali to your test solution, you will speed up the corrosion of the aluminum several times over. You cannot compare acidic or basic NaCl solution with neutral NaCl solution, these are completely different corrosion media.

Hi Dear,

May be you could look at the effect in the milieu such as release of nutrients and contribution to it, are other organism participating in the process. Actually, you should considered the resistance or time used to decay as adaptation physiological and or morphological compare in its milieu or other plant species. Expressed the texture and structure to contribute in that light.

Best Wishes,

John

You are not allowed to ask exam questions or other assignments here on RG!

My hydrogel takes 6 hrs for stable crosslinking after which I start the swelling study. Intervals are 10 mins, and I continue for 1hr after which I increase the time points depending on reaching a plateau.

Physiological and behavioral factors, gastrointestinal factors, disease-associated factors, and environmental factors that initiate the hunger center can affect the feeling of hunger.

I fully agree with Dr Philippe Tailhades, as the analisis of TGa curves are based on the loss weight percentage do you need to build the TGA curves in weight percentage to be able to compare

Yes almost certainly an experimental error. However, I would bet on the weighing procedure as the more likely problem. Specifically, since most ionic liquids are hygroscopic, I suspect some weight - in the form of condensed water - was added accidentally after the sample was weighed.

Dear Osman Uygun ,

there are three aspects, which have to be considered:

a)Ppenetration depth of your 'surface modification with iron' in your sample;

it might be surface near in the range of a few µm; but I do not know, what you have really done.

b) Penetration depth/information of XRF analysis;

this is in the range of a few 10µm; thus covering the depth of your surface modification, but covers not the whole sample thickness.

c) Information depth of TGA; I think, this is equal to the complete thickness of your sample, which I suppose to be in the mm range. So with TGA you will get a result averaged over the whole sample. Any modification of the sample close to the surface will not significantly affect the averaged result.

Dear Dr Fouad Zeidan Hamzah,

Many studies reported that an elevation in oxidative stress process is associated with weight gain but also in multiple organ dysfunction, especially liver and kidney. Here's the links of some interesting articles:

Best wishes,

Sabri

Samples acquires moisture relatively very quick. So even it you heat it in an oven and place it in an airtight bag, it get its bound moisture within a short span of time.

We generally keep the sample in TGA at around 50 - 70 deg. for 15 to 20 min for the weight to stabilize. Then we can start the ramp up of heat for the thermal analysis. If your polymer is thermally stable till around 100 deg., then you can keep the sample in TGA at around 80 to 90 deg. instead of 50 - 70 deg.

Also check please the following useful RG link:

Wesam Salah Mohamed Ibrahim

Have a look at the following RG links.

Thanks!

Kindly Visit..

Also, kindly check:

The values of the observations being zeroes are not an issue. Your issue here is the sample size. You need a larger sample size. Check this out:

I totally agree with Dr Emanuel Cooper . it seems to me that there is a partial reduction of you ferrite cations on 800-900 degrees. I would also say that the first endotherm is related to water and small organic molecules.

Hi,

These are attributed (in sequence) to (i) desorption of water molecules, (ii) labile oxygen groups (epoxides, hydroxyls) and (iii) stable oxygen-based groups (carboxyls). You might find that your thermograph is slightly different between runs in air and nitrogen depending on what you want to see.

Have a look at my study on this, might be useful:

Regards

I am not sure but may I suggest that plowing may cause a burr to form on the edge of the wear scar. This displaced material is the product of wear and contributes to the wear volume measurements but since it remains attached to the test specimen, it doesn't affect weight loss.

Also check https://harvest.usask.ca/bitstream/handle/10388/12568/GOLAKIYA-THESIS-2020.pdf?sequence=1&isAllowed=y

As per my views, the corrosion rate obtained from the electrochemical test is based on the flat (no slope) region that we chose in the anodic and cathodic parts of the curve to draw tangents. Even a small variation in site selection leads to a significant difference in corrosion rate. Whereas, corrosion rate obtained from the weight loss method gives a confident measure of corrosion rate as weight loss is a universal measurement. So, I would recommend weight loss as the more suitable method for corrosion rate measurement.

Whereas, the major benefit with electrochemical corrosion is the quantified value of corrosion potential which is definitely a more reliable, non-mathematical, and instantaneous measure of corrosion resistance.

I forget to mention that our study group also showed a large colon lengh, a symptom of reduced colitis.

In summary, our study group showed the same weigh loss, less disease symptoms and increased colon lengh but worse colon histology.

Than you

Sincerely

Jose Maria

As a suggestion, I can say that the different components in TGA analysis are eliminated at different temperatures. The mass release for water, Ca(OH)2 and CaCO3 will be different. Particularly, the attention in water should be centered around 100°C. In this case, you will see a peak around this temperature in the derivative of the mass loss. By knowing the amount of the sample used (in grams for example) and knowing the % change of the sample at his particular temperature, you can calculate how much water was released.

Vianney Andrew Yiga TG graph can be presnted as mass plotted against temperature or mass loss plotted agaainst temperature. If you plot mass vs. temperature, it starts from 100%. It, in fact, presents residual mass plotted against temperature. But if you really mean, mass loss, it should start from 0%. Please check my previous answer again carefully.

Dear Janitha,

There are two events occurring at 330.81 and 515.28 deg C.DGEBA is a symmetrical molecule and has high stability, but also it is an organic bulky molecule, hence the energy required to break DGEBA maybe substantially higher as compared to conventional organic compounds but also lower than inorganic substances. This means at 330.81deg C , there is a weight loss(probably due to cleaving and elimination at the phenylpropan2-yl region ) and the second event at 515.28 deg C because of elimination of the oxiran group.

weight loss (%) = (mi-mt/mi) *100

mi = initial mass

mt = final mass

It is important to have a representative sample size when conducting TGA analysis of cementitious or other multi-phase materials. At NIST, we generally tried to use our large volume TGA pans and get a sample size close to or exceeding 100 mg.

Also, results often depend on from which temperature you are measuring your final weight loss. In your figure 7, one can observe that already by 100 C, when the sample should be losing mostly free water, samples 5 and 6 have much less mass loss than those of 1-4. Perhaps these samples were allowed to "dry out" more prior to being loaded into the DSC. You can try renormalizing your mass loss results using the 100 C masses of each specimen as the new basis. This should definitely get rid of some of the variability between specimens.

Regarding the heat flow plot, it would be better to plot the y-axis as heat flow per unit mass as otherwise it is difficult to compare the various curves.

From the mass loss curves, the mass loss between 400 C and 500 C is usually attributed to water lost from calcium hydroxide and while it is difficult to tell exactly from viewing the curves, the six specimens appear to have fairly similar absolute mass losses between 400 and 500 C. This would suggest that the free water loss (prior to 100 C) may indeed be biasing the subsequent cumulative mass loss curves and normalizing based on the mass measured at 100 C may be a good way to go.

Good luck,

Dale

Hi Shashi, I confirm the answer of Mahmood M. Barbooti, thats exactly correct..

Corrosion rate is pretty constant after some amount of time and decreasing maybe due to corrosion product formation. The scattering is absolutely normal and the variations are most likely due to the inaccuracy of the gravimetric method

Also check https://www.sciencedirect.com/topics/materials-science/thermal-degradation-of-polymer

Agree with Mousa Numan Ahmad .

It ran in Nitrogen, Is there any chance of formation of NiO?

as I studied that metal salt taken if present in the product will decompose in that range and it's basically NiO.

It depends on quantity of consumption. Low consumption of carbohydrates affect body weight.

Yes

Dear Dr.

If possible, add potassium hydroxide in a ratio of 0.07 M. to 0.35M and have the best results.

There is a thin line between what is termed medicine and poison. Every pill has contradictions but pharmaceutical companies shields these just to be in business. There are lots of other ways to lose weight . Exploit it

Dear all,

Thank you for the explanations.

However, i am still a bit confuse with the TGA/DTG analysis. Are you referring to total weight loss or just weight loss at region where combustion occurs? What does the higher derivative weight (DTG) loss signify?

I have attached two of my result files here. According to your explanation, which materials have higher combustion temperature? @Mahmood H. M.

Thank you for helping.

The heat involved in the reactions that occur with the sample can also affect the appearance of the TG curves, as it changes the equality that should always exist between the oven and sample temperatures. There are cases in which this lag, which partly depends on the heating rate used, can be in the order of 10 ºC for more, if the reaction is exothermic, and for less, if it is endothermic. This effect can cause considerable errors, especially when it is intended to calculate kinetic constants from the thermogravimetric curves.

This effect can be observed in the TG curves of Sm (III), Eu (III), Dy (III) and Y (III) 4-Methoxybenzoates, shown in the Figure. In all curves there is a return of the TG curve for lower temperatures; as already explained, this is due to the great reaction heat involved in the thermal decomposition (4-methoxybenzoate)

Ligen Yu Thank you for replying

Yes. leptin work against weight loss

You ca use this method. we used it identify the thermal degradation of polyethylene-chitosan blend. It is a simple method. You can just use excel to find the value of Arhenius constant and Activation Energy.

Dear Sivalingam Dinesh,

Would you please determine the type of materials that have been tested, and is it possible to attached the TGA graph?

I followed weekly fasting for many years. Now I am 74 year-old and therefore, I usually avoid my dinner to keep me in good health.I am very energetic and doing all my work.

If one eats more boiled vegetables, fresh seasonal fruits, nuts than deeply fried and fatty foods, health will be good.Further, I advise that dinner must be completed by 7 PM before going to bed at 10 PM.

With normal kidney function, excess protein does not impact kidney function. In those with diabetes, metabolic syndrome, hypertension, on certain meds. for hypertension or the elderly, excess protein may be harmful. Plant-based protein is safer than animal protein in terms of the nitrogen load to the liver (and important for those with chronic liver disease) and kidneys. Protein is key to body organ repair and for satiety; skimping on protein may not serve the body's best needs. Beans and corn together constitute a complete protein when meat is a metabolic danger.

As prevention of some health problems such over weighting, diabetic, Gastric, nephritic syndromes and dyspepsia the warm clean water without medicine has perfect affect.

Thank you!

He/she need foods supporting their immune systems, including:

Hydrophobic samples can retain nonpolar solvents that volatilize at low temperatures.

I suggest that you use slow heating rate, 1 or 2 °C. min-1 to monitor the effect of mass loss.

Check the calibration of the thermobalance with the manufacturer's standard weights and the coefficients of the calibration curve.

Kindly see the following RG links and PDF attachments.

Consuming hot water won’t make someone lose weight, but it does help the process. taking warm water empty fire up your metabolism, which gives the body the ability to burn more calories throughout the day. It also clears out your intestines to prevent bloating in the body, thus getting rid of excess water weight one may be carrying. It is therapeutically used for musculoskeletal disorders such as arthritis, ankylosing spondylitis, or spinal cord injuries and in patients suffering burns, spasticity, stroke or paralysis.

Thanks for the information

Although restriction of diet often results in initial weight loss, more than 80 per cent of obese dieters fail to maintain their reduced weight. Obese people may regain weight after dieting due to hormonal changes.

It means that even though our weight is reduced, hunger hormones persist to be released in a way by which individual gain weight again.

I personally think those who are overweight or obese are deprived of fibre and complex carbohydrates in their diets. Moreover, they mainly focus on taking only simple sugars and carbohydrates in their diet. Adding a good amount of fruits and raw vegetables will increase the fibre as well as will be full of antioxidants which will help them from certain diseases. Where as intake of Vitamin C in our diets is highly recommended for better immunity. Fibre provides us with satiety and will therefore, elongate the transit time of next meal.

Health policy, education policy etc. in every country should now include active promotion of healthy lifestyle in the media. As part of this policy, informational, educational and activating programs for sports, healthy eating, preventive health check etc. should be finalized from state funds. The governments of countries should consider introducing additional taxation of confectionery enterprises and thus funds for health policy programs could be significantly increased. Obesity is a serious problem that should be taken into account in the current pro-social policies for the promotion of healthy living co-financed from state finance funds.

@ Dr. Ajay Padmawar

Garcinia cambogia (=Garcinia gummi-gutta) is a well researched plant species for weight loss. Please see the following RG links.

Thanks!

Steven Kator Iorfa Thank you for answering. Have a good day.

Mathew.... To solve instrumental problems, we run some commonly analyzed material and compare the performance. I your case, paraffin wax is an organic compound that may undergo melting and oxidation and hence the thermal records are complex. Try to run calcium oxalate, a well known reference material in thermal analysis, and examine the TG and DTA or DSC plots. If the behavior is OK as reported in the reference books, the problem will not be instrumental. When you said "negative weight loss" did you mean "gain in weight". Gain in weight will definitely refers to oxidation, where the hydrocarbons oxidize acquiring some oxygen to get carboxylic acids. The second run on the material deals with a different material and paraffin wax is no longer exists in the pan. It seems that your nitrogen purging suffers from some leaks and air finds its way to the sample and oxidize it. May you send the TG and DSC plots of the successive runs so that we may be closer to your problem... Good luck...

Dear Bisma, maybe the following papers will help you on the subject:

Hijikata Y, Yamada S. Walking just after a meal seems to be more effective for weight loss than waiting for one hour to walk after a meal. Int J Gen Med 2011;4:447-50. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119587/pdf/ijgm-4-447.pdf

Reynolds AN, Mann JI, Williams S, Venn BJ. Advice to walk after meals is more effective for lowering postprandial glycaemia in type 2 diabetes mellitus than advice that does not specify timing: a randomised crossover study. Diabetologia 2016;59:2572–2578. https://link.springer.com/content/pdf/10.1007%2Fs00125-016-4085-2.pdf

Pahra D, Sharma N, Ghai S, Hajela A, Bhansali S, Bhansali A. Impact of post-meal and one-time daily exercise in patient with type 2 diabetes mellitus: a randomized crossover study. Diabetol Metab Syndr 2017;9:64. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580296/pdf/13098_2017_Article_263.pdf

Have a good walking day, Martin

Please take a look at this useful link.

You should carefully select the degradation solvent or tool to represent your exact microenvironment for your targeted application. My personal opinion you may use the simulated body fluid (SBF) or low concentration of collagenase. It's really essential parameter to look out.

Follow

You may find some answers in this review: Franz, M. J., Boucher, J. L., Rutten-Ramos, S., & VanWormer, J. J. (2015). Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes: a systematic review and meta-analysis of randomized clinical trials. Journal of the Academy of Nutrition and Dietetics, 115(9), 1447-1463.

Any food you eat more than you need adds to your weight.

Dear Chris,

Maybe the following papers will help you on the subject:

Saslow LR, Daubenmier JJ, Moskowitz JT, Kim S, Murphy EJ, Phinney SD, et al. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. Nutr Diabetes 2017;7(12):304. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865541/pdf/41387_2017_Article_6.pdf

Saslow LR, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, et al. An online intervention comparing a very low-carbohydrate ketogenic diet and lifestyle recommendations versus a plate method diet in overweight individuals with type 2 diabetes: a randomized controlled trial. J Med Internet Res 2017;19(2):e36. https://www.jmir.org/2017/2/e36/

Brouns F. Overweight and diabetes prevention: is a low-carbohydrate-high-fat diet recommendable? Eur J Nutr 2018;57(4):1301-1312. https://link.springer.com/content/pdf/10.1007%2Fs00394-018-1636-y.pdf

Best wishes from Germany,

Martin

Hi,

The following article might answer your query

Impact of Obesity on Treatment of Chronic Hepatitis C . HEPATOLOGY 2006;43:1177-1186.

It is uncommon to observe mortality of mice implanted with RENCA cells but you may notice some drop in body weight. How many cells have you implanted at subcutaneous site? and in which strain of mice have you used?

In Russia, there was a lot of research on the applications of Titanium for aeronautical and aerospace solutions. Below I refer three papers (with direct links) as a guide for other researches. Since these papers are in Russian, translation (try Google as to scan the content) is necessary for material comprehension.