Vaccinology - Science topic

I want to build my career in Vaccinology and Clinical Research and want to know the highly respectful professors in this field to follow their work and academic production. I also need to know the professors that I can choose from to be my supervisors.

For a Microbiologist interested in the work in Vaccine Development and Clinical Research, and wants to study Microbiology, Epidemiology, Immunology, Public health, and Infectious Diseases, is it better to make a master in Vaccinology or Microbiology and Infectious Diseases ?

I want to obtain a Master Degree in Vaccinology and Clinical Research, so I want to know the best Universities or Research Centers that provide this program.

The major principle behind mRNA based technology in vaccine design and function lies in it's use to convey specific or choice transcript, encoding one or more immunogen(s), into the host cell cytoplasm as subsequent expression here, generates translated protein(s) within the membrane, which are either secreted or intracellularly located.

This is finding use to therapeutically tackle difficukt-to deal with pathogens.

As pathogens are updating there evasive tactics within the body system to shrug-off counter immune attacks on them, it is appropriate for the scientific community to update and upgrade technology and precision tools to tame and check these pathogens.

Your views are welcome and nice, as we keep brainstorming on this sensitive issue in the Science of Infectious diseases and our deck of control and check-mate efforts, dear beloved colleagues and associates.

Thank you and pax shalom to me and to you all

To know the various applications of reverse vaccinology along with their success and failure rates.

I would like to better understand how each of the vaccines we currently recommend work. So essentially my question is about your favorite source for vaccinology, but I am interested in details that are not so readily available in sources like the CDC website. What type of immunity is necessary for protection for each infectious disease we have a vaccine against? Why do we need multiple doses and boosters for certain vaccines? How did we arrive at the conclusion that we need this many dose administrations and boosters (seminal studies)?

How likely is it that a young person who received the MMR vaccine as a child and later developed leukemia and bone marrow aplasia will catch measles from close proximity with a sick person and develop disease? What about other vaccine-preventable diseases? 

Should vaccine clinical trials be conducted when not much is known about an infection? Barely a month of being declared ebola-free by the WHO the West The African state of Liberia has recorded more than two fresh Ebola outbreaks-one resulting to the death of a 15-year old since declared Ebola free by the WHO. Sierra Leone is also at risk for similar outbreak. In Guinea a former Ebola patient was tested positive for the virus after receiving clinical trial vaccine for Ebola. Giving the new information emerging about ebola these days with regards to reinfection and new outbreak is it wise for vaccine clinical trials for ebola  to continue or is it better for such clinical trials to wait until a clearer picture about ebola is obtained? From all indications those 'new' ebola cases emerging from areas previously declared ebola free are not new infection but recurrent infection.

I would like to know what is the best approach between prevented number of cases for every 1000 vaccinated individuals and the decreasing lethality of cholera in the vaccinated region when it comes to assess the Oral Cholera Vaccine Efficacy during a mass vaccination campaign in Sub Saharan Africa.

I was seeking to understand if there is an extent for a protein subunit to perform immunological response, like molecular weight, size, structure? or any limitation that should be present for the body to act against it?

Hello, I am Ronald Perraut, you cited one of my papers about vaccinology and Saimiri monkeys. We presently continue to develop P. falciparum Ag candidates.

Last week, I watched a talk show on TED Talk about Nanopatch for needle less vaccine delivery method. I am impressed.

How can I culture (in vitro) gut biopsies which I will stimulate with a vitamin A metabolite and harvest at different time points (day 1 , 4 , 7, 8, 10) to measure expression of polymeric immunoglobulin receptor mRNA.

To know the various applications of reverse vaccinology along with their success and failure rates.

There are many kinds of detergents could be applied in protein purification and added in vaccine.

Does anyone know the additive agent list that can be used in vaccine so far?

For example, signaling motif, T cell or B cell binding site, hydrophobic region, and so on. For reverse vaccinology.