Vaccination - Science topic

Could the side effects have become permanent?

There are many benefits to vaccinating the population against HPV, such as reducing the incidence of CIN2+ related to vaccine genotypes. And those who receive the HPV vaccine will experience an advantage in the transformation of HPV genotypes. How will this HPV-related epidemiological feature change in the future? Perhaps it is related to the original HPV prevalence characteristics of the population in that region.

I have data from the our experimental model - where we analyze the immune response following BCG vaccination, and then the responses and clinical outcome following Mtb infection of our vaccinated models. Because we cannot experimentally follow the very same entity after evaulating the post-vaccination response also for the post vaccination plus post infection studies - we have such data from different batches. Is it possible to do correlation here between post vaccination responses of 5 replicates in one batch (in different vaccine candidates) versus 4-5 replicates in vaccination & infection from another batch? I ask this because we are not following up the same replicates for post vaccination and post infection measurements (as it is not experimentally feasible). If correlation is not the best method, are there other ways to analyze the patterns - such as strength of association between T cell response in BCG vaccinated models versus increased survival of BCG vaccinated models (both measurements are from different batches)? We have several groups like that, with a variety of parameters measured per group in different sets of experiments.

Thanks for your responses and help.

How can you say that the blood obtained from those who have been vaccinated is not a risk?

Hello, I have a study where we are measuring the time between full COVID-19 vaccination and infection with the virus.

I have 3 kinds of answers

A: participants with known vaccination time and infection time after vaccination

Time to infection is known

Event has occured during study period

B: participants with known vaccination time but didn't contract the virus during the study period

Time to infection is unknown

Event has not occured

C: Participants who got infected BEFORE vaccination

Time to infection is known (negative?)

Event has occured before "study beginning point"

Now my question regarding the coding is

A- Event:TRUE

Time to event: whatever it is

B- Event:False

Time to event: the entire duration of

study

C-Event:???

Time to event: ???

would that be correct?

how do I deal with data C?

Thanks in advance.

I have a question. Do prior immunity to a virus-like particle vaccine platform affects its immunogenicity for the next vaccination? For example, if we vaccinate an individual using a chimeric VLP consist of an antigen of interest fused into influenza M1 protein as the core, will it have a lower immune response if the individual were vaccinated with other VLP-based vaccine containing the same M1 protein? Will it happen as with the viral vector vaccine?

For the Covid Johnson vaccine, is one dose sufficient for a person already vaccinated (3 months after the vaccine) or is a second dose necessary for better protection?

Thanks in advance

There is scientific evidence of mRNA and vectorial vaccines' genotoxicity.

mRNA vaccines induce immunodepression increasing vulnerability to communicable and non-communicable diseases ( cancer) and have a high rate of serious adverse effects, including death. Many otherwise healthy young people have died

Scientific evidence is supported by epidemiological data that show an increase in the infection risk from VOC in vaccinated people and in oncologic patients.

Moreover, I suggest reading Christine Cotton's expertise about the mRNA vaccines' unreliability.

In Florida, there was an 83% increase in mortality in vaccinated people.

We proposed on Research gate an International Research Manifesto for the withdrawal of mRNA and vectorial vaccines. if you agree you could sign it for building an international pressure lobby and there is an open discussion on Researchgate about this topic.

Reference on Research Gate

The literature reports that COVID-19 vaccination has altered the course of the pandemic and has saved millions of lives. The inadequate access to vaccines in the developing world and low-income countries has limited the impact of COVID-19 vaccinations reinforcing the need for global vaccine equity and coverage. The effectiveness, safety, cost and side effects by various vaccines has been questioned. A number of COVID-19 vaccines have been assessed in the first year of the COVID-19 epidemic. Researchers and companies may now support the best COVID-19 vaccine for the developing world and the global population.

RELEVANT REFERENCES:

A. Watson OJ, Barnsley G, Toor J, Hogan AB, Winskill P, Ghani AC. Global impact of the first year of COVID-19 vaccination: a mathematical modelling study. Lancet Infect Dis. 2022 Sep;22(9):1293-1302.

B. David A Henry, Mark A Jones, Paulina Stehlik, Paul P Glasziou, Effectiveness of COVID‐19 vaccines: findings from real‐world studies, Medical Journal of Australia, 10.5694/mja2.51479, 216, 8, (431-431), (2022).

C. COVID-19 Infection and Anti-Aging Gene Inactivation. Acta Scientific Nutritional Health 4.5 (2020): 01-02.

D. COVID-19 and Cardiovascular Disease in the Global Chronic Disease Epidemic. J Clin Med Res. 2022;4(1):1-2.

How do you think COVID-19 countermeasures taken by states and governments comply with the human rights guarantees established by national Constatutions and the International Human Rights Treaties? Among those measures are :

-mandatory vaccination

-lockdown

-mandatory usage of masks

Can a dog treated with cyclosporine for complex atopic dermatitis be vaccinated normally? It is safe? induces the expected response? could develop the disease for which was vaccinated? How should the vaccination schedule be managed?

Hypothetical case discussion. With vaccination coverage as high as 90% in many areas of India. Should an elderly who is unvaccinated till now had symptom of flu one year ago, be vaccinated .....or we can assume he has developed natural immunity. What are the side effects of COVID vaccine in Elderly?

Hello everyone.

I am doing a research where I am collecting attitude changes on COVID vaccination after reading excerpts from two different news outlets (I chose Times and Fox). Since the same questionnaire is done two times for each participants, I figure that a paired t-test is probable here. However, the attitude to the source materials is also related to the political stance of the participants, so I need to include the interaction between their stance and the news they read in the analysis, and I am not sure how I do it. So right now I have:

IV1: which news outlet they read (coded 1 and 2)

IV2: what are their political stance (collected as a slider of 1-100)

DV1: their attitude towards COVID vaccine before reading the information

DV2: their attitude towards COVID vaccine after reading the information

How could I perform an paired t-test under these circumstances? Or do I need to use other methods?

Thank you in advance!

Under National Animal Disease Control Program , India we are vaccinating only 4-8 months old female calves. My question is why this narrow range ?

Hello,

I am currently formulating an optimization model that integrates vehicle routing problem and vaccine supply chain. The model includes delivering vaccines to vaccination centers and on-spot locations representing individuals requesting to be vaccinated at home. The objective function includes maximizing the amount of doses delivered to both customers but, since the number of doses demanded by vaccination centers is significantly larger than on spots'. the model will just focus on delivering to vaccination centers and ignore the other since its effect on the objective function value is negligible. I tried to solve this by multiplying the on spot's term by a factor representing the ratio between both demands to make them equally important to the model. but I kept getting biased results. So, I formulated 2 different objective functions where each objective maximizes one customer doses why having a constraint that forces the vehicles to deliver a specified percentage of the demand of the other customer.

my question is: can I consider this model as bi-objective and treat the objectives as conflicting ?since maximizing one of these objectives will be on the account of the other taking into account that both objectives have the same unit.

Can children who have been vaccinated for hepatitis still get acute hepatitis? If yes, why did this happen?

Literature suggesting hepatitis / liver injury following COVID vaccination. A latest peer reviewed article suggests SARS- CoV -2 vaccination (Pfizer)can elicit CD8 T-cell dominant Hepatitis (Autoimmune hepatitis).Details attached in document .Should such rare side effect be taken into consideration during vaccination?

I wrote this week's blog post with one of our PhD students, Christina Baker. Christina is conducting a study of school nurses to find out the most commonly reported barriers to COVID-19 vaccination for children. Many of them are linked to Intuitive-mind thinking rather than to Narrative logic: https://sites.google.com/view/two-minds/blog

We recorded the date of vaccination of people of different occupational background and want to analyse how occupation affected their first dose of vaccination. If there is any relation to a certain group who took or received the vaccination earlier than others.

Hi dear friends,

The attached image is belong to a 12-year-old boy, who developed such complications on the surface of his body (two legs, back, face and abdomen). It was occurred about 3 days after the injection of Sinofarm vaccine, and is accompanied by severe itching. The boy is currently in hospital. The COVID-19 test was negative in this child, but it seems to have been a side effect of the vaccine.

Dear specialists, if you have experience or a solution for this treatment, I would be grateful for your valued comment.

Thanks in anticipated

Kindly regards

Jalil

Could the fact that young people are generally less affected than seniors by complications linked to SARS-CoV-2 be explained in part by their vaccination coverage?

In Quebec, the "Act Hib" vaccine began to be given against invasive Haemophilus influenza type B infections in 1988.

The "Prevnar" vaccine was introduced in 2004 against invasive pneumococcal infections.

Do these vaccines help effectively protect people under the age of 16 and 36 from bacterial pneumonias associated with coronavirus?

If this hypothesis is plausible, should we not promptly offer this same vaccine protection to the elderly?

Source: https://msss.gouv.qc.ca/professionnels/vaccination/piq-programmes-et-noms-commerciaux-des-vaccins/dates-de-debut-et-de-cessation-des-principaux-programmes- of-free-vaccination-in-quebec /

Les vaccins contre contre les infections invasives à Haemophilus influenza et à pneumocoques protègeraient-ils des complications reliées au SRAS-CoV-2 ?

Le fait que les jeunes gens soient généralement moins affectés que les ainés par les complications reliées au SRAS-CoV-2 pourrait-il s’expliquer en partie par leur couverture vaccinale ?

Au Québec, le vaccin "Act Hib" a commencé à être donné contre les infections invasives à Haemophilus influenza de type B en 1988.

Le vaccin "Prevnar" fut introduit pour sa part en 2004 contre les infections invasives à pneumocoques.

Est-ce que ces vaccins contribuent à protéger efficacement les personnes âgées de moins de 16 et 36 ans contre les pneumonies bactériennes associées au coronavirus ?

Si cette hypothèse est plausible, ne devrions-nous pas promptement offrir cette même protection vaccinale aux personnes âgées ?.

Are antibodies generated through vaccination recognise all new variants of COVID_19?

Antibodies, Vaccination,New variants,COVID_19

Recently number of vaccines has been developed for COVID-19. How long the immunity is expected to be lasted after vaccination.

I am trying to conduct a study on the reasons behind the reluctance of people to get vaccinated against the Covid 19 epidemic

What are the reasons or variables behind people's reluctance to take the vaccine?

What is the appropriate method also to do research of this kind?

What is the appropriate sample size for the study?

Thanks for all the help or discussion.

Is there any standard questionnaire Tool available to assess knowledge of adult vaccines?

Pulse Oximeter: A New Normal in Hospitals?

Pathology and an aspirational strategy of treating COVID-19: Well Understood? Or do we need to sacrifice few complicated unlucky cases, when vaccinating crores of people? Where are we heading towards?

Are we able to stave off of the COVID-19 virus successfully by ceasing its replication at an early stage? To what extent are we able to achieve the hyperactive immune response in each individual as the infection progresses?

Metabolism being unique in individuals, to what extent, the immunosuppressant drugs such as Dexamethanose (steroid); Tocilizumab (anti-inflammatory); and Remdesivir (antiviral drug – helps in some cases by shortening the hospital stays in the absence of its ability to assure the survival) - react positively; and under what circumstances, these medications tend to react negatively? Why did the antibiotics Azithromycin and Doxycycline get failed in speeding up the recovery of outpatients? Even, antibody-rich (convalescent) plasma did not improve the outcome? Have we deduced the right dose of anticoagulants towards blood-clot (which enhances the risk of gastrointestinal and intracranial bleeding) for some individual? Are we sure about the dosage and its (critical) timing during which these medications are to be given to the patients?

Why did more than 20 European countries stop AstraZeneca’s COVID-19 vaccine (based on blood clots, low platelet counts and internal bleeding as against typical strokes or blood clots)?

Following Acetaminophen, to what extent, monoclonal antibodies (laboratory-made proteins that mimic the body’s own immune response and that are designed to block the virus from attaching to cells) really have helped in reducing the risk of hospitalization in outpatients?

Whether the falling of blood oxygen level below 94% can confirm the enhanced levels of immune signaling molecules in the blood?

How are we going to treat immune thrombocytopenia (blood disorder) following the Pfizer and Moderna vaccines against COVID19 or in few cases, the cerebral venous thrombosis (CVT) following the AstraZeneca vaccine?

Vaccination has been extensively used to prevent, eradicate and control infectious diseases. If it can be made for plant its process will be ....but can it be on progress .

The Anti-Circumsporozoite Antibody Response Of Children To Seasonal Vaccination With The Rts,S/As01e Malaria Vaccine.

Issaka Sagara et al 2021.

Clinical Infectious Diseases, ciab1017,https://doi.org/10.1093/cid/ciab1017

Abstract

A trial in young African children showed that combining seasonal vaccination with the RTS,S/AS01E vaccine with seasonal malaria chemoprevention reduced the incidence of uncomplicated and severe malaria substantially compared to either intervention given alone. This paper reports the anti-circumsporozoite antibody response to seasonal RTS,S/AS01E vaccination in children in this trial.

Abstract

Background

A trial in young African children showed that combining seasonal vaccination with the RTS,S/AS01E vaccine with seasonal malaria chemoprevention reduced the incidence of uncomplicated and severe malaria substantially compared to either intervention given alone. This paper reports the anti-circumsporozoite antibody response to seasonal RTS,S/AS01E vaccination in children in this trial.

We are all living in a strange era since last year due to the pandemic of COVID-19, so we are all seeking to find the truth about basic parameters of it.

As everybody knows, any research needs reliable data, so we need data.

But, despite the plethora of available online sets, the critical ones are not always presented publicly.

For example in Greece we do not have online data for next categories, all related to COVID-19:

In Greece we do not have also next data online:

The only available set was next:

Recently a paper about inside and outside ICU mortality was published with correspondent author having next past jobs

(All those jobs were at the same Organization, now called "EODY", which is the Greek CDC for all of you that you do not know the Greek reality)

Not to make you tired:

Thank you for your patient to read such a big test,

I am waiting for your thoughts,

Demetris

What do you think about the origin of the new coronavirus (COVID-19)?

Now there are different reports about the main origin of the coronavirus. Some media say the virus may have been synthesized in the laboratory.

What do you think about this? Will the virus soon be cured or vaccinated? Please share your comments.

I published the test results of FMD vaccine Quality results of 54 batches of vaccines in 2014 ( ) and got entangled in several inquiries and legal cases because some of the traitors of the nation were busy defending the producers of substandard FMD vaccines in the Country. Since then Indian Veterinary Research Institute vaccinating its dairy animals thrice in a year against FMD had two major outbreaks of the FMD one with Type "A" and recently with type "O".

Do you still feel that the National Animal Disease Control Program (NAD-CP) of India may succeed using the Indian FMD Vaccines twice in a year when it proved ineffective even after vaccination thrice in a year, that too in the best Veterinary Science Institute (IVRI) in India? Or it may be mere wastage of about 12330 Crore (~123 million) rupees. https://www.linkedin.com/posts/bhoj-raj-singh-47b291118_fmdabrcp-fmd-diseaseprevention-activity-6873858445586563072-KmU_

Is anybody aware of any relationship between no feeling conscious fear (but with normal physiological response) and any disfunction of the inmunitary system (e.g. not achieving serological protection after being vaccinated)?

Who is now working very hard with return of America to its active membershipnow WHO is concentrating on vaccinations,here are some activities,

Hello.

I am research student, I will ask for any research about nursing role to improve compliance of childhood vaccination in Jordan

regards

In view of the continuous evolution of science, especially in the field of mathematical epidemiology, and the ideology observed in this direction, I formulated a thesis project proposing a hybrid model broadening the field of understanding of infectious diseases, especially Covid-19. This model is a combination of the well known classical SEIR model and another newly introduced model under experimentation giving more data on the geographical aspect of the said disease needed to enhance the accuracy of the existing epidemiological systems or to build one as needed.

The deadly Coronavirus Disease 2019 (COVID-19) has claimed numerous lives and the number is increasing day by day. So, in this situation, a vaccine has been expected to decrease the mortality rate worldwide and save us from this disaster. But there have been some complications reported from the vaccination process, however rare or mild those are. Now that some vaccines have been approved for emergency use, we want to investigate whether these vaccines cause any after-effects. You are cordially invited to participate in this study by providing your valuable response if you have taken at least one dose of the covid vaccine.

Thanks in advance for your valuable contribution.

I am in the beginning steps of my psychology thesis development, and just focused on doing as much research as possible. My working title is, “Combating COVID-19 vaccine misinformation: Effects of corrective strategies on vaccination knowledge, attitude, and intention,” but the DVs may change as I am still looking for validated items to measure them. I am having trouble finding theories directly tackling corrective strategies or debunking misinformation. It would be highly appreciated if anyone here has an idea or tips for me.

Thank you for your attention.

@Mention All

INVITATION TO PARTICIPATE IN A SURVEY ON Parents intention towards Covid-19 vaccine for their kids

This questionnaire is aimed at examining parents' intention towards vaccination for their kids and how conspiracies belief affect their intention. Your participation can help ascertain negatives or positives intentions towards vaccination and which factors effecting in vaccine hesitancy during the pandemic.

Click on this link https://docs.google.com/forms/d/e/1FAIpQLSfL6x2xlcWgL-rtxz6kqHT3RXSh9Dc59r5gnWekqK2j18YTMQ/viewform?usp=sf_link

If you have any questions, please contact shahani@mail.ustc.edu.cn

Thank you for your support.

I observed local hypersensitivity in cattle after 24 hrs post vaccination

Mass vaccination for Covid-19 is going to start very soon. Whom do you think should be given priority for vaccination? Senior citizens, frontline workers or students? Why?

Dear RG community,

As far as I know, antibodies are different in vaccination and natural infection. While natural infection produces antibodies against different parts of the virus, vaccination produces antibodies against only parts of the virus that are present in the vaccine. For instance, nucleocapsid proteins are not present in the vaccine, so antibodies are not produced against nucleocapsid proteins by vaccination. Is there any authorized COVID antibody test to differentiate a person’s immunity as either natural infection or vaccination? (For instance, a person gains immunity from vaccination not a natural infection, or a person gains immunity from vaccination 70% and natural infection 30%, etc.)

On the other hand, both vaccination and natural infection can produce the same type of antibody. For example, both vaccination and natural infection trigger to produce antibodies against spike proteins. Is there any difference between these two proteins? Can we differentiate antibodies against spike proteins that are triggered by either vaccination or natural infection?

Thank you.

What's the difference in usage of the 3 tetanus toxoid containing vaccines - DTap, Tdap and Td?

Hello everyone, I'm trying to calculate the number of events between 2 dates in Stata, eg from birth to 1st vaccination date, etc.

Can someone please help me with syntax?

Thank you

Hello all,

I hope you are doing good.

Well, could you please share with me recent comparative research studies about the covid-19 vaccinations?

Currently, I am interested in studying the effectiveness and side effects of each type of vaccine according to experiments done via research work.

Many thanks,

Where can I find an authoritative current covid vaccine efficacy table stratified by age and vaccination status for a large/well-studied population - e.g. Israel or the US or UK?

This is the best source I can find, and I'm not happy with it. I've tried to view the underlying sources, but I can't read Hebrew, google and Safari translate don't work, and immediate source is a freelance journalist. http://twitter.com/IvoryHecker/status/1423447625844633604

Everything else seems to be cherry picked or hearsay.

Dear researchers,

I hope all of you are doing well.

Recently, most of people are worried about taking the vaccine when it is ready in 2021.

And their is one question all of them asked

((((((Are you going to Get vaccinated with COVID-19 vaccine? )))))

The answer normally 😊

No answer yet????

And i want to share this with you to discuss about it and how we should deal with it

In addition, as a scientist how can we help at this stage.

Thanks

Dr. Zainab T Al-Sharify

What is the level of antibody titres developed after COVID_19 Vaccination in patients with autoimmune diseases?

Autoimmune diseases,Antibodies,COVID_19 Vaccination

Dear RG members

As we know that we generally take full dose of the COVID vaccination of same kind... But is there any study which allows us to take different doses as a full dose. ..?

Thank you all.

Covid-19 vaccination

*Covid19 vaccine worldwide survey For its side effect and efficacy.*

*Plz also spread it with your known groups and encourage everone who is vaccinated*

*Plz fill it if u vaccinated. This is for research purpose*

*If already filled then ignore*.

Dr. VIVEK JAIN

DEPARTMENT OF PHARMACEUTICALSCIENCE MOHANLAL SUKHADIA UNIVERSITY UDAIPUR, RAJASTHAN, INDIA

🙏🙏🙏

It has been proven that those vaccinated in the new vaccines excrete spike proteins through breath, saliva and urine. According to my inquiry to the Federal Environment Agency, there is no research on what these excretions could cause in the long term, e.g. via the water cycle, for damage to nature and the environment - as it is well known from other drug residues, in particular from the birth control pill, the infertility of fish and Amphibians in part. If so much is being vaccinated globally with the new vaccine - can one estimate the risk of long-term serious damage to nature and the environment without prior research for whatever reason? How long do z. B. These spike proteins outside the body and what do they break down into?

It seems that people with blood group 0-positive or 0-negative have fewer or no symptoms after being vaccinated against COVID-19 disease (either by Astra Zeneca or Pfizer vaccines), while people with blood group A, AB, or B, either negative or positive, suffer from headaches, malaise, nausea, and have a slight fever after being vaccinated against COVID-19 disease.

Is it possible that blood type is related to this observation?

Thank you!

#COVID #COVID19 #VACCINATION #SIDE #EFFECTS

Dear peers, I am looking for the data, showing the vaccination number globally per vaccine type. When I evaluated side effect of the vaccine usually the data state the number rather than percentage of people who reported side effects. I am especially interested with impact of each vaccine in % for the menstrual cycle if anyone has the access to those data, I will appreciate your help in finding relevant database.

Can Spearman rank order correlation be used when the relationship between two variables is not fully monotonic, but is close? The attached graph shows a plot of such a relationship, including a fitted regression line. One variable is a state's daily cumulative number of persons fully vaccinated for covid-19, and the other is the daily number of new covid-19 cases in that state. The date range is mid-January through early June of this year.

As Covid-19 trajectory enters the phase of mass vaccination some early positive signs have been reported, not in the least, significant reduction in severe illness. At this stage in our view it is essential for the research and public policy community to have the necessary tools, resources and capacity to distinguish between two scenarios:

The capacity to understand and monitor developing epidemiological situation for these scenarios can be essential not in the least because significant presence of the infection in a community with high level of vaccination carries the risk of producing new, more resistant strains as was and is being observed with possibility to cause unanticipated "out of the blue" flare ups.

In our view, research and policy cannot and should not rely exclusively on conventional mass testing as the incentive for the wide public to participate may diminish in that phase producing skewed results. Rather, effective "non-invasive" instruments and methods of monitoring and detection should be developed and introduced for continuous monitoring of the situation. These can include ongoing and possibly automated testing of air; surfaces; sewage etc in the areas of mass aggregation such as stations, airports, shopping malls, large factories, residences etc. as well as new methods such as voluntary self-testing with easy immediate reporting in the community.

Now a days in the Asia Sub-continent (including Pakistan and India), a popular message is circulating on social media (as well as on local newspapers) with reference to the French Nobel laureate, "Luc Montagnier", claims that everyone who has taken any COVID-19 vaccine will die in two years.

This has caused a lot of anxiety among those who have taken the vaccines. It is also promoting vaccine hesitancy among those yet to be vaccinated.

Please give your detail arguments in the light of available scientific resources.

I have a question about T-cell recall assays. We vaccinated mice and wanted to see if there was a T-cell response against our tumor cells. There was no tumor challenge. We pulsed DCs from naive cells and then cocultured these DCs with the T-cells. But we also seeded the tumor cells and cocultured the T-cells with them. Could anyone shed light on why we would do both of these?

My guess is that the pulsed DCs activate naive T cells and can show that you have tumor specific T cells but they were not activated by the vaccination. But if you do it with the whole tumor cells and there is a response, it means the T cells were already activated by the vaccination. Is this correct?

I am currently working on a thesis on "analysis of public perception and acceptance of the COVID-19 vaccination process using the Structural Equation Modeling method". There are 6 variable used in the research : Behavioral Beliefs, Attitudes towards Vaccination, Perceived Norms, Motivation to Comply, Perceived Behavioral Control, and Intentions to Receive Vaccination

However, these results seem to make no sense to me:

I used this journal (Bridging the gap: Using the theory of planned behavior to predict HPV vaccination intentions in men, 2013, Daniel Snipes) as references for the research

A study revealed that most vaccines do not completely protect against infection, although they do prevent symptoms. That is why people who have received vaccinations may carry and spread pathogens without knowing it. They may also cause a pandemic.

Due to the huge leap in COVID-19 vaccinations around the globe, I presume that this disease will be eradicated promptly (hopefully).

However, is it OK to use retrospective data of COVID-19 in our research?

I used the data of last year (2020), but because of the journal's long processes, I think that the data I used in my paper will become old.

Is it going to be accepted, or it's not interesting for journal editors and reviewers?

Thank you for your assistance with this matter.

I am currently working on a thesis on "analysis of public perception and acceptance of the COVID-19 vaccination process using the Structural Equation Modeling method". There are 6 variable used in the research : Behavioral Beliefs, Attitudes towards Vaccination, Perceived Norms, Motivation to Comply, Perceived Behavioral Control, and Intentions to Receive Vaccination

However, these results seem to make no sense to me:

I used this journal (Bridging the gap: Using the theory of planned behavior to predict HPV vaccination intentions in men, 2013, Daniel Snipes) as references for the research

RNA vaccines follow a different strategy, without using any "real" component of the virus at all. Instead, researchers aim to trick the human body into producing a specific virus component on its own. Since only this specific component is built, no complete virus can assemble itself. Nevertheless, the immune system learns to recognize the non-human components and trigger a defense reaction. So May I ask, What are your opinions about the safety and efficacy of the BNT162b2 mRNA Covid-19 Vaccine?

Vaccination is in its First phase in India. The front line is to be vaccinated yet. In this situation opening of institutes may be dangerous for the life of children.

Is it possible to use the plasma of the SARS-COV 2 vaccinated people instead of the convalescent plasma as part of the treatment for SARS-COV 2?

What are the priorities of COVID_19 vaccination programs in changing social and epidemiological landscapes?

Priorities, Vaccination programs, Epidemiological landscapes.

As COVID-19 has shown the strain variations, various mutants, if we developed vaccination at one place, r we sure that perticular gene has not mutated take example of E-gene of coronavirus.

It's important to know that all three COVID vaccines were tested on people who ate their usual diets. That means the vaccines have been shown to be effective without any special nutritional preparation. But there is a handful of eating strategies that simply make sense to best support the body's needs, both before and after have the jab. https://www.health.com/condition/infectious-diseases/coronavirus/what-to-eat-before-and-after-covid-vaccine

And since, the goal of the vaccination is to generate acquired immunity against the virus, as a result, these recommendations may be useful to support the body's immune system...So, what foods are recommended to eat before and after receiving the COVID vaccine, and why?

All comments and contributions are welcome.

Now we reach to the point of solution for covid 19,often develop in lifelong immunity when we have had a disease.  However, some diseases may lead to serious complications and sometimes death. The aim of vaccination is to obtain this immunity without any of the risks of having the disease.

When we vaccinate, we activate the immune system's "memory." During vaccination, a weakened microbe, a fragment, or something that resembles it, is added to the body. The immune system is then activated without us becoming sick. Some dangerous infectious diseases can be are we

aredoing prevented in a simple and effective way. For some diseases, vaccination provides lifelo.So we are moving to the right direction?

Public health authorities claim that no one is safe from COVID-19 until every one is safe. This has translated into a goal to vaccinate everyone who can be vaccinated. Logistically, however, it will take 7 years to vaccinate 2 million adults per day (365 days a year, no weekends or public holidays) across the world in order to vaccinate earth's 5.8 billion population over the age of 15 with a single dose. (Some well resourced countries are struggling to achieve 100k jabs per day). So what's the point?

We are not even discussing the hundreds of thousands of vaccinators needed at work everyday for 365 days a year for 7 years to achieve 2 million jabs per day, or the possibility of new vaccine-resistant virus variants and mutations, or the endemic unknowns that can overtake the best designed plans, as well as Murphy's law etc. It appears that, once the developed world is accounted for, everything may grind to a halt or settle into an opaque, haphazard process without a clear end in sight. It may be that the only solution to vaccinate "everyone" within a year or two years is to inject half the world with a saline placebo?

Everyone is advocating COVID-19 vaccination for Herd Immunity. How judicious is the COVID-19 Vaccination? कोविड-१९ टीकाकरण में कितनी समझदारी है? https://azad-azadindia.blogspot.com/2021/03/how-judicious-is-covid-19-vaccination.html

In my country, Algeria, the rate of cases tested positive for covid is low. But newly vaccinated people no longer take precautions, and they infect others. What are the possible scenarios in these circumstances, and within what timeframe?

My hypothesis is that vaccination in infected/hospitalized patients with worsening of covid-19 could cause an increase in the levels of neutralizing antibodies, improving the prognosis and preventing deaths. Even with the bias of treatments with immunosuppressants (anti-inflammatory drugs, for example), the activation of the production of these neutralizing antibodies could be faster since patients have already had previous contact with the virus. In addition, studies show that individuals with long term covid-19 improve symptoms after vaccination. So, why not try this strategy?