Science topic
Uveitis - Science topic
Uveitis is an inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)
Questions related to Uveitis
Please see our latest article:
Anterior-Segment Optical Coherence Tomography Unlocks Novel Perspectives: Lacking Iris Anterior Limiting Layer Signal in Uveitis
My colleagues and I are trying to induce EAU (experimental autoimmune uveitis) in Lewis Rats, though we are having difficulty reaching the higher diseases scores, even with increased levels of adjuvant and ocular antigen. We're reached a clinical score of 2, but never higher.
We're worried that our mixing technique (for the Uveitis cocktail) might be inappropriate, so we are looking for any techniques or hints for preparing our disease cocktail for injection.
Currently we're using 100ug IRBP + 500ug CFA/H37Ra per Lewis Rat. The cocktail is premixed by pipet, then sonicated for 5min. Finally the emulsion is drawn in and out of a 23g needle/syringe until thick and cream colored. Any suggestions on how to alter the protocol are much appreciated.
Diagnosis and identification of Rift valley fever by rapid test in animals.
There are many studies with different values of incidence and prevalence of uveitis.
I am currently working on a uveitis intervention study, I need to know the duration of effect of periocular triamcinolone acetonide in posterior uveitis? I. E. When do you expect to reinject?
I am trying to detect antibodies in human serum of patients with uveitis directed against normal human eye tissue. I know that the ciliary body contains some immunoglobulins naturally. Can anyone advise a method of doing this. We are going to try incubating tissue with serum and applying an appropriate secondary AB. But I am concerned re non specific binding
How to detect causative agents for ERU in the anterior chamber of eye?
Ophthalmologists often order FFA in uveitis cases. When should it be done and how does it help in management ?
and other patients with spondyloarthritis from different regions of the earth?
The patient is 17 years old girl. Apart from being obese, there was no previous health problems. In April 2015 she underwent tetanus and diphtheria vaccination.
Suddenly, 17 AUG 2015, she mentioned intermittent scotomas. After the next 3 days, she had blurred vision and visual field defect (central blurred spot) in the right eye. Next, transient scotomas appeared in the left eye. Over next 4 days visual acuity decreased to inability to read.
Since the beginning of the symptoms she was seen by several ophthalmologists, who finally diagnosed: APMPPE.
Solu - Medrol (1000 mg/day) for five days (since 27 AUG 2015) was given, then methylprednisolon orally 48 mg a day is being continued. Slight improvement of visual acuity in the left eye was occured.
Toxoplasmosis, Toxocarosis, Lyme disease, Syphilis, CMV, EBV, HIV, HCV were excluded.
Chest X - ray image and brain MRI (without angio -) was normal .
Basic biochemical tests were normal, apart from urinary tract infection, which was succesfully treated.
ANA – screen, anty PR-3 (c-ANCA), anty MPO (p-ANCA), serum protein electrophoresis, IgA, IgM, IgG – the results were within normal limits. Monoclonal protein and onconeural antibodies were absent. .
How are eye anatomy and physiology involved in this feature?
40yr old man on treatment for 9 months for chronic uveitis. On glucocorticosteroids, now complains of peri-orbital headaches in a remote part of somali. I want to refer for blood tests and radiology and further insight as to the cause?
Leptospira can cause uveitis in horses, are there reports for the same in buffaloes?
