Urinary Tract Infections - Science topic

Recurrent urinary tract infection (rUTI) is a significant public health problem in women. General measures to prevent recurrence include behavioral changes and increased fluid intake, cranberry ingest, use of methenamine hippurate, antibiotic prophylaxis, D-mannose, probiotics, or vaccines. We conducted a literature review of the latest updates on...

Background Knowledge: Diabetic patients at heightened risk for urinary and renal problems resulting from metabolic abnormalities. Urine dipstick examination is a quick and non-invasive diagnostic method often used to identify abnormalities in many clinical parameters, such as nitrites, protein concentrations, ketone bodies, and leukocyte esterase....

U nedostatku suvremenih nacionalnih smjernica za liječenje infekcije mokraćnih putova u djece mlađe od 12 godina (u RH postoje ISKRA smjernice za dijagnosticiranje i liječenja infekcija mokraćnog sustava u osoba starijih od 12 godina) (1) ovo je jedan od pokušaja rezimiranja nekoliko suvremenih inozemnih smjernica te rezultata istraživanja koji su...

Background: Urinary tract infections (UTIs) are among the most prevalent bacterial infections affecting millions of people worldwide each year. They are characterized by the presence of pathogenic microorganisms in the urinary system, leading to symptoms such as frequent urination, burning sensations during urination, and lower abdominal pain. Whil...

To identify independent risk factors for urosepsis in diabetic patients with upper urinary tract stones (UUTS) and develop a prediction model to facilitate early detection and diagnosis, we retrospectively reviewed medical records of patients admitted between January 2020 and June 2023. Patients were divided based on the quick Sequential Organ Fail...

AIM: To investigate predictive value of the systemic immune-inflammation index (SII) combined with the distal ureteral diameter ratio (UDR) for early breakthrough urinary tract infection (BT-UTI) in children with primary vesicoureteral reflux (VUR). METHODS: A retrospective analysis was conducted on 150 VUR patients admitted to ShangHai Children's...

Background: Urinary tract infections (UTIs) are among the most common bacterial infections in children, and the antibiotic susceptibility in the youngest patients remains poorly understood. This study aimed to describe the distribution of uropathogens and their antibiotic susceptibility, focusing on oral formulations. Methods: Data from the first m...

Medical diagnostics is an important step in the identification and detection of any disease. Generally, diagnosis requires expert supervision, but in recent times, the evolving emergence of machine intelligence and its widespread applications has necessitated the integration of machine intelligence with pathological expert supervision. This researc...

Worldwide, urinary tract infections (UTIs) have an increased incidence, especially in women. Recurrent UTIs (rUTIs) appear in less than three months in 80% of the cases, being associated with age, sexual activity, or diabetes mellitus. Antibiotics represent the first line of treatment for rUTIs after the diagnosis based on a positive mid-stream uri...

Diabetes mellitus (DM) is a chronic condition that lowers life expectancy and quality of life when left untreated or improperly managed. Infections, both common and pathogenic, such as emphysematous pyelonephritis, malignant otitis externa, mucormycosis, and Fournier's gangrene, are more common in diabetic patients. Because patients with diabetes h...

A sepse neonatal é uma infecção grave em recém-nascidos, que desencadeia resposta inflamatória exagerada, sendo causa de morbimortalidade. Um fator de risco significativo é a colonização por estreptococos do grupo B durante a gravidez, indicando antibioticoterapia intraparto profilática. Portanto, investigar infecções na gestação é crucial, dada a...

Candiduria is a condition in which Candida species are found in the urine. Candiduria is commonly found in hospitalized patients, especially those with diabetes mellitus and those receiving medical care, especially using urine catheters. Although Candida is a normal part of the body’s flora, certain species can opportunistically cause urinary tract...

Streptococcus agalactiae or Group B Streptococci (GBS) is a lesser-known pathogen of Urinary Tract Infection (UTI) especially in developing countries. There have been very few cases/series reported from India. This study over four years noted approximately 1% of positive cultures to be GBS at par with world literature. Out of a total of 10,508 posi...

This research aims to design and validate a machine learning model to predict the probability of urinary tract infections within 90 days post-urostomy in bladder cancer patients. Clinical and follow-up information from 317 patients who had urostomy procedures at the First Affiliated Hospital of Shanxi Medical University (May 2018–May 2024) were ana...

Objective: The objective of this study is to examine the sociodemographic factors associated with ketoacidosis events in these patients and describe the effect of analog insulin and blood ketone levels on the occurrence of ketoacidosis. Methods: A retrospective observational study was conducted at Dr. M. Djamil Padang Hospital with a cross-sectiona...

Introdução: A enterocolite necrosante neonatal constitui uma emergência clínica caracterizada por inflamação intestinal severa ou necrose, sendo relacionado a uma alta morbimortalidade entre os recém-nascidos. Objetivo: Descrever os fatores predisponentes associados à enterocolite necrosante entre recém-nascidos pré-termo. Metodologia: Trata-se de...

The aim of the current study was to determine prevalence of multiple drug resistance bacteria among patients suffering from Urinary Tract Infections (UTI’s). This study was carried out at Lahore in Sir Ganga Ram Hospital from 1 March to 30 May 2014. It involved cases with or without clinical symptoms of UTI and they were studied retrospectively....

Introduction: Neurogenic bladder disorders after spinal cord injury (SCI) are often problematic with urinary incontinence (UI) and recurrent urinary tract infections (UTIs) contributing to patient morbidity. Our study objective was to provide a current snapshot of the frequency of UI and UTIs in the SCI population while also quantifying their assoc...

Pregnancy leads to a number of structural and functional changes in the urinary system, which makes females susceptible to urological complications. This review aims to discuss the epidemiology, complications and prevention and management of urinary tract infections (UTIs), kidney stones and bladder dysfunction in pregnancy. UTIs are the most commo...

Urine culture is still the gold standard for Urinary Tract Infection (UTI) diagnostics, but it takes a long time and expensive. The flow cytometry is a more practical, fast, and reliable test for diagnosing UTI. The study was conducted to determine the validity of the bacterial count with UF 5000 flow cytometry compared to urine culture and to eval...

Background/Objectives: The management of urinary tract infections (UTIs) has become an increasingly challenging medical intervention. This study explores whether adoption of a precision medicine model could improve the management of acute uncomplicated pyelonephritis (uAPN) or complicated UTIs (cUTIs) compared with the standard of care approach, in...

Samenvatting Inleiding Alternatieve behandelopties voor urineweginfecties (UWI’s) zijn nodig door toenemende antibioticaresistentie. Dit onderzoek richtte zich op de veiligheid, effectiviteit en behandelingstevredenheid van blaasspoelen met kraanwater (BSK) bij kathetergebruikers met recidiverende UWI’s. Methode In dit prospectieve, observationel...

Urinary tract infections (UTIs) are a significant health concern, particularly for people living with dementia (PLWD), as they can lead to severe complications if not detected and treated early. This study builds on previous work that utilised machine learning (ML) to detect UTIs in PLWD by analysing in-home activity and physiological data collecte...

Urinary tract infections (UTIs) are among the most common bacterial infections during childhood. Early diagnosis and prompt treatment are necessary to prevent long-term sequelae. Pyuria, a key diagnostic marker for UTIs, is defined as the presence of ≥5 white blood cells per high-power field in urine obtained by centrifugation of urine and microsco...

Urinary tract infections (UTIs) represent a prevalent health concern among the female population, with anatomical and physiological determinants such as a shorter urethra and its proximity to the rectum augmenting vulnerability. The presence of Escherichia coli and various other pathogens plays a significant role in the etiology of these infections...

Introduction Urinary Tract Infections (UTIs) are a significant health problem worldwide, especially among women. methenamine hippurate has been proposed as a preventive measure against recurrent UTIs. This updated systematic review and meta-analysis aimed to evaluate the effectiveness of methenamine hippurate in preventing UTIs, incorporating the l...

Urinary tract infections (UTIs) are among the most prevalent bacterial infections, with Klebsiella pneumoniae emerging as a significant multidrug-resistant pathogen, particularly in healthcare settings. The frequent utilization of β-lactams and fluoroquinolones has contributed to the reduced clinical application of trimethoprim-sulfamethoxazole (TR...

Background/Objectives: The rise in multidrug-resistant pathogens complicates UTI management, particularly in empirical therapy. This study aimed to develop and describe a Bayesian hierarchical weighted-incidence syndromic combination antibiogram (WISCA) model to optimize antibiotic selection for adult patients with community-onset UTIs. Methods: A...

To determine the variations in the costs of the prophylaxis of recurrent urinary tract infections (RUTIs) among different prevention protocols, a prospective observational multicenter study on 1614 women receiving RUTI prophylaxis was conducted. The patient groups were as follows: Group A (n = 444): conventional suppressive antibiotic therapy; Grou...

Background Urinary tract infection is considered a common bacterial infection. Nowadays there is an increase in the irrational and inappropriate use of drugs. Adverse drug reactions have been reported to be a main cause of morbidity, hospital admission, and sometimes death. For this, it is very important to do the analysis of prescriptions and to s...

The multicenter prospective randomized trial of clinical and microbiological efficacy of cefepime in combination with fluorothiazinone or placebo was conducted to expand the possibilities of empirical therapy for patients with complicated urinary tract infections. The primary endpoint of the study in the MITT population was the clinical cure and pa...

Urinary tract infections (UTIs) affect approximately 150 million people globally, yet diagnosing this prevalent condition remains challenging. Misdiagnosis and inappropriate antibiotic prescriptions are common, contributing to the growing problem of antibiotic resistance among pathogens. Current diagnostic methods require 2-3 days to identify the c...

Objectives: Bloodstream infection (BSI) is a common sequelae of urinary tract infections (UTIs) and it requires early detection and appropriate antibiotic therapy. This study analyzed the clinical and microbiological profile of secondary BSI resulting from UTI caused by Enterobacterales. Methods: In this retrospective study, National Healthcare Saf...

Urinary tract infections (UTIs) are a significant public health concern, affecting millions worldwide, particularly women, with Escherichia coli being the most common causative agent. The anatomy of the urinary tract, particularly in females, makes it more susceptible to infection due to a shorter urethra and closer proximity to the anus. Additiona...

In the original publication [...]

Despite much promise in overcoming drug-resistant infections, clinical studies of bacteriophage antibacterial therapy have failed to show durable effectiveness. Although lysogeny plays an important role in bacterial physiology, its significance in diverse microbiomes remains unclear. Here, we tested the following hypotheses: 1) urinary microbiome p...

Urinary tract infections (UTIs) are one of the most common bacterial diseases both in communities and in hospitalized patients, and at the same, time they are one of the most common indications for the use of antibiotics. UTI guidelines are generally available nationally or internationally, but they do not address all aspects of UTI treatment for d...

Introdução: A Sociedade Brasileira de Nefrologia estimou que cerca de 10 milhões de pessoas no Brasil tinham doença renal crônica em 2019. Em 2022, 5.303 transplantes renais foram realizados no país, destacando-se o município de Juiz de Fora como um dos maiores centros de referência em transplantes renais. Objetivos: O objetivo deste trabalho é ava...

En los pacientes con diabetes tipo 2 se evidencian estudios dónde estas infecciones generadas por enterobacterias y otros uropatógenos se mantienen prevalentes, debido a su vulnerabilidad por la propia enfermedad. El objetivo del estudio fue evaluar infecciones del tracto urinario en pacientes que padecen diabetes mellitus tipo II en la parroquia E...

Millones de personas son afectadas anualmente por infecciones bacterianas, son más comunes en las mujeres debido a varios factores biológicos y anatómicos que aumentan la probabilidad que las bacterias accedan y colonicen el tracto urinario. La susceptibilidad microbiana, que es la capacidad de los patógenos para ser inhibidos o eliminados por anti...

Introduction: Urinary tract infections are common in pediatrics. Knowledge of local resistance patterns is crucial to guide empirical antibiotic therapy. We aimed to review the pathogens implicated in urinary tract infections, local resistance patterns, and the impact of switching first-line empirical antibiotic regimens.Methods: We conducted a cro...

Introduction: Urinary tract infections (UTIs) are among the most common bacterial diseases in children, affecting 3-5% of girls and 1% of boys, and leading to significant antibiotic exposure in this population. Initial UTI treatment is often empirical, based on symptomatology without microbiological confirmation. Objective: This study aimed to iden...

Introduction: The Brazilian Society of Nephrology estimates that approximately 10 million people in Brazil had chronic kidney disease in 2019. In 2022, 5,303 kidney transplants were performed in the country, with the city of Juiz de Fora standing out as one of the largest reference centers for kidney transplants. Objectives: The objective of this s...

Background: Bacteria belonging to the Enterobacteriaceae family are responsible for most urinary tract infections globally, with disproportionate burden levels among vulnerable populations. Aim: This study evaluated the burden and also characterized the species of bacteria associated with a disadvantaged population, the geriatric group, in the Port...

Background: Prelabour rupture of membranes among pregnant women is a common obstetrics problem encountered by the obstetricians. Objective: This present study was aimed to see the association of premature rupture of membrane and urinary tract infection among pregnant women. Methodology: This cross-sectional study was conducted in the Department of...

La infección del tracto urinario es la segunda enfermedad infecciosa más común después de las infecciones respiratorias y causa las visitas ambulatorias más comunes, siendo la Escherichia coli la más común en pacientes hospitalizados y en la comunidad. El objetivo del estudio fue determinar la resistencia antimicrobiana de enterobacterias en infecc...

Group B Streptococcus (GBS) causes various infections in adults, including urinary tract infection (UTI) and asymptomatic bacteriuria (ABU). Some bacteria that cause ABU can utilize urine as a substrate for growth, which can promote asymptomatic colonization in the host. An analysis of diverse GBS isolates associated with ABU and UTI for growth in...

Urinary tract infections (UTIs) are among the most common bacterial infections worldwide. They occur in the urinary system when a microorganism, commonly present on the perineal skin or rectum, reaches the bladder through the urethra, and adheres to the luminal surface of uroepithelial cells, forming biofilms. The treatment of UTIs includes antibio...

Introduction: Uropathogenic bacteria like Escherichia coli (UPEC) and Pseudomonas are the most common agents of Urinary Tract Infection (UTI). Recently, the ability of UPEC to invade urothelial cells and to form Intracellular Bacterial Communities (IBCs) has been described which can be missed out during routine diagnosis and can lead to recurrent i...

A 50-year-old man with polycystic kidney disease had living donor kidney transplant. Simultaneous right sided native nephrectomy was done to give a space for graft kidney. He developed three episodes of urinary tract infections within 2 months after transplant; one episode was associated with septic shock and rise serum creatinine. Two urine cultur...

Hospital-Acquired Infections (HAIs) in the ICU significantly impact patient morbidity, mortality, and length of stay. Objective: To determine the incidence of HAIs, identify key risk factors, and analyze their impact on clinical outcomes in ICU patients. It was prospective observational study. Methods: A total of 220 ICU patients were included. Dat...

Background and objectives Urological complications after kidney transplantation, due to the ureteroneocystostomy, are associated with significant morbidity, prolonged hospital stay and even mortality. Ureteral stents can minimize the number of complications but are not consistently used, as previous studies were retrospective in nature. We aim to p...

La bacteriuria es la presencia de bacterias en la orina sin síntomas, mientras que la pielonefritis es una infección grave de los riñones que puede resultar de la bacteriuria no tratada, donde las infecciones del tracto urinario son más comunes en mujeres, especialmente contagiosas durante la actividad sexual, y pueden provocar complicaciones grave...

A serious worldwide health emergency has been brought on by the growth of multidrug-resistant (MDR) microorganisms, which are difficult to treat with traditional antimicrobial drugs. This emphasises how urgently novel therapeutic approaches are needed to combat antimicrobial drug resistance (ABR). To increase the efficacy of treatment for resistant...

Urinary Tract Infection (UTI) is a significant health problem, especially in hospitals, where the use of urethral catheters is one of the main risk factors. Catheterization can increase the possibility of infection because it is the entry point for microorganisms into the urinary tract. The use of antibiotics is the main choice in the treatment of...

Bacteria are prokaryotic organisms, many of which are part of the normal flora in the human body without causing infection. The infection pattern caused by this aerobic bacteria can very depending on factors such as the duration of catheter use, the patient’s health condition, and hygiene levels. Catheter-Associated Urinary Tract Infections (CAUTI)...

A bactéria Ureaplasma spp. pode causar infecções do sistema reprodutor feminino (SRF), submetendo mulheres a várias complicações, apesar de ser considerado um patógeno tratável com antibióticos. A falta de diagnóstico rápido e de notificação compulsória compromete a implementação de ações contra esses microrganismos no Brasil. O objetivo deste estu...

Background and Objectives: Urinary tract infection (UTI) is a common comorbidity in diabetic patients, making up one of the causes of sepsis. This study aims to develop a nomogram to predict the risk probability of sepsis in diabetic patients with UTI (DPUTIs). Materials and Methods: This is a retrospective observational study. Clinical data for DP...

ZET Amaç: Önemli bir halk sağlığı sorunu olan idrar yolu enfeksiyonlarında en sık karşılaşılan etken Escherichia coli (E. coli)'dir. Çalışmamızda E. coli sıklığını ve giderek artmakta olan antibiyotik direncini araştıran makaleler derlendi. Derlenen bu makalelerin artan antibiyotik direnci için bir farkındalık oluşturması ve etkin bir tedavi için y...

Background and Objectives: The European Association of Urology (EAU) Guidelines on Prostate Cancer note emerging evidence suggesting that antibiotic prophylaxis may not be necessary for transperineal prostate biopsies. However, formal recommendations are pending further research. This meta-analysis compares urinary tract infection (UTI) rates follo...

El estudio titulado “Susceptibilidad antimicrobiana de bacterias causantes de infecciones del tracto urinario en Latinoamérica” tiene como objetivo analizar la resistencia bacteriana a los antibióticos para tratamiento de infecciones urinarias en la región. El enfoque de la investigación es revisar estudios recientes que evalúen la susceptibilidad...

Due to bacterial resistance to antimicrobials, antibiotic therapy for urinary tract infections (UTIs) has become a major challenge for clinicians. The present work aimed to compare the antimicrobial susceptibility profiles of 53 uropathogenic Escherichia coli (UPEC) isolates, assessed using the disk diffusion method and two automated systems (PHOEN...

Urinary tract infections caused by Gram-negative bacteria (GNB) are among the most common infections and a significant cause of sepsis. The increasing prevalence of multidrug-resistant (MDR) bacteria poses challenges to empirical treatment. Colistin may be used a last-resort antibiotic for treating MDR infections, but this requires the rapid determ...

Introdução: As infecções do trato urinário representam uma das complicações médicas mais prevalentes no período da gravidez. Alterações fisiológicas, hormonais e imunológicas tornam as gestantes mais suscetíveis ao desenvolvimento dessas infecções, que podem variar desde bacteriúria assintomática até pielonefrite grave. A presença de ITU está assoc...

Antecedentes: Las infecciones profundas en neonatos hospitalizados en unidades de cuidados intensivos -UCIN- están mediadas tanto por factores propios del paciente como por la realización de procedimientos invasivos y el uso de instrumental médico, siendo las más frecuentes y graves las infecciones sanguíneas como bacteriemia relacionada con catéte...

Background: Urinary tract infections (UTIs) are a common complication after kidney transplantation. The aim of this study was to evaluate the impact of pre-existing diabetes mellitus and post-transplant diabetes mellitus (PTDM) on the occurrence of pyelonephritis in kidney transplant recipients. Methods: We performed a retrospective analysis which...

Background: All over the world, hundreds of millions of population suffer from common bacterial infections of the urinary tract every year. An increased risk of death, morbidity, and increased healthcare expenses in the critical care unit is linked to catheter-associated urinary tract infections (CAUTIs), which occur when bacteria enter the urinary...

Recurrent urinary tract infections (UTIs) in elderly patients with comorbidities can present diagnostic challenges. Extrapulmonary tuberculosis, particularly urogenital tuberculosis, is a rare but important cause of persistent genitourinary symptoms. We describe the case of an 83-year-old female with hypertension, diabetes, chronic kidney disease,...

Background: Urinary tract infections (UTIs) are common in pregnant women due to significant changes during gestation. UTIs can affect any part of the urinary system and are typically caused by bacteria, though fungi and viruses can also be responsible. Asymptomatic bacteriuria (ASB is frequent in pregnancy and must be treated to prevent serious mat...

Healthcare-associated infections (HAI) are a critical public health problem, with 30 to 40% of infections related to the urinary tract system. These urinary tract infections (UTIs) are considered one of the most common microbial infections in hospital settings and everyday community contexts, where approximately 80% are highly correlated with urina...

Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infections (UTIs). Invasion into bladder epithelial cells (BECs) on the bladder luminal surface via type 1 fimbria is the first critical step in UPEC infection. Although type 1 fimbria expression increases during UPEC invasion of BECs, the underlying regulatory mechanisms remai...

The aim of this study was to investigate the differences between nosocomial and community microorganisms isolated from patients with UTI by determining their bacterial profile, antibiotic resistance and ability to produce biofilms. A retrospective study, based on bacterial isolates from consecutive urine samples collected between January 2019 and D...

In Aotearoa New Zealand, urinary tract infections in humans are commonly caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli . This group of antimicrobial-resistant bacteria are often multidrug resistant. However, there is limited information on ESBL-producing E. coli found in the environment and their link with human clini...

Introduction Urinary tract infections (UTIs) represent a rare postoperative complication following thyroidectomy. Objective This study aimed to assess the clinicodemographic factors associated with the development of UTIs and subsequent outcomes among patients undergoing thyroidectomy. Methods This retrospective study used the National Surgical Qua...

Urinary tract infections (UTIs) are among the most common bacterial infections of both dogs and humans, with most caused by uropathogenic Escherichia coli (UPEC). Recurrent UPEC infections are a major concern in the treatment and management of UTIs in both species. In humans, the ability of UPECs to form intracellular bacterial communities (IBCs) w...

Introduction: Urinary tract or UTI infections, are extremely frequent and can have a negative impact on the individual's well-being and standard of life. The overall rate of UTI prevalence was 33.54%, with 66.78% of cases occurring in females and can be correlated to Mutrakruchhra. Aim- To study the effect of Vidariyadi Vati on the management of Pi...

The horseshoe kidney (HSK) is a common renal abnormality mostly asymptomatic. This may be linked to chromosomal and organ anomalies. A 27-year-old male patient presented with mild recurrent lower abdominal pain associated with dysuria. No history of renal disease. Laboratory investigations revealed red blood cells (RBC), white blood cells (WBC), an...

Objective: This study aimed to determine the phylogroups and specific virulence genes of uropathogenic Escherichia coli (UPEC) in patients suspected of urinary tract infections (UTIs) at Al-Hawija General Hospital in Kirkuk. Methods: A total of 120 urine samples were collected from patients exhibiting clinical signs of UTIs. The presence of bacteri...

Introduction: This study analyzes urinary tract infections (UTIs) in a hospital in Central Portugal over a five-year period, focusing on bacterial prevalence, patient demographics, and antibiotic resistance patterns. This investigation aims to provide insights that can guide improved infection control and treatment strategies. Methods: A total of 6...

The use of urinary catheters is very common in hospitals. Urinary catheters are the most common cause of bacteriuria. Urinary tract infections are the cause of more than 1/3 of all hospital-acquired infections. Most of these infections (at least 80%) are caused by invasive procedures or urinary tract instrumentation, usually in the form of catheter...

Background/Objectives: Urinary tract infections (UTIs) caused by multidrug-resistant (MDR) bacteria pose a considerable challenge due to high treatment failure rates and associated healthcare costs. This pioneering study evaluates the effectiveness of personalized autovaccine therapy in managing recurrent UTIs in patients with MDR bacteria, aiming...

The pathogenesis of recurrent urinary tract infections (rUTIs), a common problem in the female population, is becoming better understood following recent studies of bacterial persistence and intracellular bacterial communities. Incorporating these new insights, we propose pulsed antibiotic therapy with intracellular activity as a possible treatment...