Publications related to Tumors (10,000)
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Pulmonary hamartomas (PH) are benign lung malformations accounting for approximately 3% of all lung tumors. Their incidence is relatively low, ranging from 0.025% to 0.032% in the adult population.1 Most of these tumors occur in the peripheral lung parenchyma, while about 10% of cases are endobronchial lesions.
Patients with PH are often asymptoma...
Green-synthesized RESV– ¹⁹⁸ AuNP enable sustainable immunomodulation, selective prostate tumor cellular targeting, and favorable in vivo biodistribution. β (0.96 MeV) emission reprograms M2 to M1 macrophages and induces potent tumor volume reduction.
Tumor tissues obtained in the clinical setting typically have low purity and display treatment-associated genetic heterogeneity, contributing to variants at low variant allele fractions (VAF). We present a pan-cancer landscape and the therapeutic impact of somatic variants detected at low VAF (≤10%) from tumor tissues in 331,503 patients, across 78...
Os elevados custos de hospitalização para o tratamento de doenças ressaltam a importância da abordagem precoce de tumores e outras patologias dermatológicas. A demora no atendimento agrava o quadro clínico e, consequentemente, aumenta os custos para o Sistema Único de Saúde (SUS) do Brasil. Objetiva-se descrever a experiência de implantação do Ambu...
Giriş: Tümörü infiltre eden lenfositler, tümör mikroçevresindeki immün sistem hücreleridir ve kansere karşı oluşan immün yanıtta kritik rol oynar. Meme karsinomunda, tümörü infiltre eden lenfositlerin miktarının prognostik ve prediktif önemi olabileceği ortaya konmuştur. Çalışmamızda, meme kanserine ait tümör dokularındaki inflamatuar hücreler, TIL...
With the advancement of medical technology, people have made some new progress and breakthroughs in the treatment of tumors and cancers, especially in the aspect of genetic intervention, This paper introduced the process of different gene therapy strategies for treating diseases and the application of various gene therapy strategies in tumor treatm...
CONVENTIONAL PAPILLARY CARCINOMA ARISING WITHIN A FOLLICULAR ADENOMA IN A THYROID ; A RARE COLLISION TUMOR
This study utilizes a 3D bioprinted stromal model to obtain EVs that differ based on proximity to a tumor. A 3D tumor spheroid model displayed increased spheroid diameter after treatment with normal tumor adjacent fibroblast EVs.
Pulmonary embolism is a blockage of a pulmonary artery (or one of its branches) by a blood clot (thrombus), fat, air, or tumor cells, which obstructs blood flow to lung tissue.
Die Nuklearmedizin war traditionell stark diagnostisch ausgerichtet, hat sich in den letzten Jahrzehnten jedoch zunehmend auch therapeutisch weiterentwickelt. Ein zentrales Beispiel dieser Entwicklung ist die Radioligandentherapie, die diagnostische und therapeutische Ansätze verbindet: Radioaktiv markierte Liganden werden zunächst zur Bildgebung e...
Die Nuklearmedizin war traditionell stark diagnostisch ausgerichtet, hat sich in den letzten Jahrzehnten jedoch zunehmend auch therapeutisch weiterentwickelt. Ein zentrales Beispiel dieser Entwicklung ist die Radioligandentherapie, die diagnostische und therapeutische Ansätze verbindet: Radioaktiv markierte Liganden werden zunächst zur Bildgebung e...
Die Nuklearmedizin war traditionell stark diagnostisch ausgerichtet, hat sich in den letzten Jahrzehnten jedoch zunehmend auch therapeutisch weiterentwickelt. Ein zentrales Beispiel dieser Entwicklung ist die Radioligandentherapie, die diagnostische und therapeutische Ansätze verbindet: Radioaktiv markierte Liganden werden zunächst zur Bildgebung e...
Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, with liver metastasis posing a significant therapeutic challenge. Within the “seed and soil” paradigm, disrupting both tumor cells and their supportive microenvironment is essential to suppress disease progression. Here, we utilized single‐cell transcriptomics of clinical...
Enhanced photothermal and photodynamic therapy by supressing of the HSP90-HIF1α pathway is a promising strategy for the treatment of triple-negative breast cancer (TNBC) as it can accurately target tumor tissues and improve therapeutic efficacy.
In the published publication [...]
Die Nuklearmedizin war traditionell stark diagnostisch ausgerichtet, hat sich in den letzten Jahrzehnten jedoch zunehmend auch therapeutisch weiterentwickelt. Ein zentrales Beispiel dieser Entwicklung ist die Radioligandentherapie, die diagnostische und therapeutische Ansätze verbindet: Radioaktiv markierte Liganden werden zunächst zur Bildgebung e...
Immunocytokines have emerged as a promising modality in cancer therapy, capitalizing on the precision of antibodies to deliver cytokines selectively to tumours. Yet, the toxicity of the cytokine portion of...
Traditional antitumor strategies often require sufficient time to assess the effectiveness according to changes in tumor structure. Once ineffective, patients may miss the critical window for pursuing alternative treatment options. Herein, a manganese sulfide nanoplatform loaded with proton pump inhibitor (PPI) is developed. This nanoplatform is de...
For small renal tumors, nephron-preserving treatment, including partial nephrectomy or ablation therapy, is recommended. According to major guidelines, ablation therapies are advised for patients who are deemed not suitable to undergo surgery due to an advanced age or the presence of comorbidities. However, compared with surgery, ablation therapy c...
Discapacidad cognitiva en el daño cerebral adquirido: visibilización y sensibilización El daño cerebral adquirido (DCA) es consecuencia de una lesión súbita, que afecta de forma abrupta el desarrollo y la identidad de la persona. Implica secuelas físicas, cognitivas, emocionales, comportamentales y sociales, así como cambios en la calidad de vida,...
This case emphasizes the complexity of LS and the need for more comprehensive surveillance strategies, particularly in those with MPTs, to enable early detection and improve management.
Perirenal schwannomas are rare benign tumors that may radiologically mimic renal malignancies. We report the case of a 39-year-old asymptomatic woman with an incidentally discovered perirenal mass initially suspected to be renal cancer. Intraoperatively, the lesion appeared well-encapsulated and extrarenal. Complete excision was performed, sparing...
Benign epididymal neoplasms are rare in children. While epidermoid cysts commonly occur in the testis, scrotum, and foreskin, they are only rarely found in the paratesticular region. We present the first reported case of an epidermoid cyst arising from the epididymis in a 3-year-old boy. Testis-sparing surgery was performed to obtain a definitive d...
Kanker merupakan keganasan yang dapat menyerang pada berbagai usia, termasuk usia anak. Anak merupakan salah satu kelompok usia rentan. Kanker dapat menyerang dari usia bayi hingga remaja baik laki-laki maupun perempuan. Jenis kanker pada anak dapat dikelompokkan menjadi dua kelompok besar yaitu keganasan darah dan tumor padat. Penelitian ini bertu...
Pisu molekular altuko azido hialuronikoak (PMA-AH) anti-hantura ezaugarriak dituen osagaia da zelulaz kanpoko matrizean (ZKM); pisu molekular baxukoak (PMB-AH), ostera, hantura bultzatzen du. CEMIP (ingelesezko cell migration inducing protein) hialuronidasaren adierazpen altua hantura kronikoa bereizgarri duten gaixotasunetan deskribatu izan da (os...
Amaç: Radyoterapi (RT) serviks kanserinde kullanılan etkili bir tedavi yöntemidir. Bu çalışmanın amacı RT uygulanmış serviks kanserli hastaların tedavi sonuçları ve prognostik faktörler açısından değerlendirilmesidir. Materyal ve Metot: Kliniğimizde adjuvan ve definitif RT uygulanmış evre IB-IVA serviks karsinomlu toplam 142 hasta retrospektif olar...
Kanser, çok sayıda moleküler faktörden etkilenen çok yönlü ve karmaşık bir hastalıktır. Bunlar arasında tümör baskılayıcı genler ve moleküler şaperonlar, hücresel homeostazisi sürdürmede ve kötü huylu dönüşümü önlemede önemli roller oynar. Bu çalışmada, TP53, RB1, BRCA1, BRCA2, PTEN, APC, CDKN2A, SMAD4, NF1, VHL, ve WT1 gibi majör tümör baskılayıcı...
This study compared machine-learning models for predicting recurrence-free survival (RFS), disease-specific survival (DSS), and overall survival (OS) using clinicopathologic data from 1,621 stage I/II primary cutaneous melanoma patients. Our time-to-event models achieved concordance indices of 0.829 for RFS, 0.812 for DSS, and 0.778 for OS. Tumor t...
Breast cancer is a highly heterogeneous tumor. Changes in receptor status often are observed at the time of recurrence and metastasis. This phenomenon of receptor transformation has an important impact on the choice of treatment and prognosis of patients. In this paper, we will review the literature related to receptor transformation in recent year...
Correction for ‘Transformable nanodrugs for overcoming the biological barriers in the tumor environment during drug delivery’ by Xuejian Li et al. , Nanoscale , 2023, 15 , 8532–8547, https://doi.org/10.1039/D2NR06621A.
A phaeochromocytomatosis – a phaeochromocytoma peritoneumon való egy-, vagy többgócú implantálódása a tumor sebészeti eltávolítása során kialakuló ritka szövődmény. Esetbemutatásunkban egy sebészeti szempontból irreszekábilis, két ciklus I131-MIBG kezelés mellett progrediáló phaeochromocytomatosisos beteg 14 éves kórtörténetét ismertetjük. A tüneti...
Romatoid Artrit (RA) ve Ankilozan Spondilit (AS) kronik, inflamatuar, sistemik hastalıklardır. Bu hastalıklar kontrol altına alınmadığında hastalarda morbidite ve mortalitede artışa neden olmaktadır. Genellikle eklem tutulumu görülmesine rağmen inflamatuar süreçten vücudun diğer organları da olumsuz etkilenebilmektedir. RA ve AS’nin patogenezinde p...
