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You can think coating adhesive and then producing packaging tape with the BOPP Film.
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It is important that it is flame corona treatment because when adhesive is coated on the surface of the bopp film, it has been determined that the adhesive applied to the surface with flame corona treatment lasts longer.
In other words, the usage time of the tape is extended.
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Hi everyone,
I am a 3rd-year student at the University Of Bolton studying psychology, psychotherapy and counselling.
My dissertation concerns psychedelics as a mental health treatment and understanding people's journeys.
I would appreciate if you or anyone you know could help me by participating in my study.
My questionnaire can be found at: https://forms.gle/o8qfeGLCifyj4eq19
I appreciate your help with this!
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Congratulations on your studies Michael. I wish you much luck !!! Psychodelics or "enteogens" as the first term was more of the 70's, are not "my cup of tea" as I do prefer what Assaglioli called "the soft path". That is meditation and development of Consciousness to arrive to the same "state".
"The experience" is in a level/layer of higher consciousness (see the difference with capital "C") and without the need of seeing things on the move or the change of colors or the interaction with mother plants or other let's say external "artifacts", the deepest "Aha" experience of opening, understanding and connection with higher realms of the psiche and the mysterious "beyond" is the very same.
That's why I do not need psychoactives to feel, recognize and experience real changes in my Conscious life (that, then, become "permanent" and non "temporary" as may be with them). Plus, I do not have the negative effects in my neurons, blood and liver.
I'm not against the use of enteogens (and much more less against the people that "intake" them). I just say that I do not use them or like them FOR ME. And yet, as an experienced Integral Psychologist I would recommed the use for those people which are soooo intellectual, so CLOSED in their tunel vision that do not think (much more less "sense" that there's anything else than what they can see, touch and hear.
I would recommed those people to read with open mind and good heart, William James, Suzuki, Assagliogli and Ken Wilber PLUS meditate (taught by an experienced meditation master) from half an hour to one hour every day during one year.
Then if they have not change anything in their inner perception of life and "things"; in their view about "reality", then and only then, I would recommed to take "enteogens" (preferably natural psychoactives like: peyote, psilocybe, salvia divinorum or the most used lately, the ayahuasca) to crack their rigid armor !!!
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Hello everyone, I'm working on treatment engagement during therapy for my studies. I want to do research on factors influencing (barriers to and facilitators of) treatment engagement (remaining in therapy, being committed and involved in the process) with suicidal adults and I can't find much about this for now. Please can you help me by providing some references?
#suicide #suicidal #treatmentengagement
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Dear Chloé Muscat,
There is a document called "Framework for recovery-oriented practice" available in PDF format on the internet at: www.health.vic.gov.au/mental health Published by the Mental Health, Drugs and Regions Division, Victorian Government Department of Health, Melbourne, Victoria.
This document might be of great help and if you would like to receive this publication in an accessible format, please phone 03 9096 7873 using the National Relay Service 13 36 77 if required
All the best
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COVID-19 is mainly a respiratory disease that affects the lung, although other organ structures with endothelium seems to be affected too.
When should we do imaging?
What is the aim of the imaging?
How can it help with management?
Do you agree with the following consensus statement?
How will you adjust your own practice and difficulties encountered? Why?
Ref:
The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Chest. 2020 Apr 07.
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I personally believe that imaging examinations in covid should be rapid, simple and executable at the patient's bedside and therefore I believe that the most useful is LUS.
Unfortunately still today is used the chest X-ray that has been proven useless.
The purpose of LUS is to stage the pathology in order to predict its evolution, unfavorable or favorable. With LUS and blood gas analysis we can determine which patients should be discharged at home in a period when bed meals are scarce in all hospitals.
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Dear Researchers,
Preliminary data of various studies showed the proportion of the population from Black (in New York), Asian (UK) and other minority ethnic backgrounds and people from low income are highly deprived with COVID-19. These groups reported higher COVID-19 mortality rates irrespective of population density. Furthermore, most of these minority groups are aged 50-79. Since the epidemic started, several studies have confirmed these findings. It is interesting to discuss the reasons behind these adverse outcomes and also share your experience about COVID-19.
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Please contribute to this question with your assured knowledge.
In treating cells for different time spans like 24h, 48h and 72h, should we seed different numbers of the cells suitable for relevant treating time?
If yes, what is the method to define the best seed number?
If not, in the case the cells continue to grow more in higher treatment times (though the viability decrease as drug concentrations increase), does higher treatment time worth to continue studying?
Thanks for your participation.
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Thank you all for your answers
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I'm looking at the effect of the drug on lung function. What test should I perform for pre and post control vs pre and post treatment? Control group had measurements taken before and after recieving placebo and same for the tratment group, however they were administered a drug. Different subjects were used in control and treatment groups.
I'm very thankful for help.
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Hello Sandra,
It depends on how your DV (lung function) is quantified. If you can consider it as a continuous variable of interval strength or better, then it sounds to me as if a one-way (treatment vs. control), ancova would be a logical option. Pre-measures would be used as the covariate; post-measures as the DV.
Good luck with your work.
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I work in community corrections and the research suggests the Duluth model is innefective at best whjen compared to CBT-type treatments. The question is, are we increasing the risk of DV offending if the perpetrators are mandated to offend?
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Yes as Michael and Nada indicate there has been a paradigm shift away from the Duluth model of intervention as the literature has been clear that a CBT or solution focused intervention has rendered more positive outcomes for perpetrators.
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Since more men and older women contract coronavirus, will it be useful to additionally use estrogen for its treatment or prevention?
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I wonder why the jump to hormonal reasons, there are so many other factors involved.
Could be that women tend to look after their health more, tend to be quicker to respond to indicators of poor health. behaviors over and above hormones.
Or there is more older women dying simply because they are a larger percentage of that population. Likewise more men may be dying simply because there is a larger percentage of males in the population, ok not that big a difference... to explain the higher death rate.
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I am looking for a recent diagnosis for chikungunya virus through computational biology techniques.
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Molecular docking
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After reading the article in JAMA https://jamanetwork.com/journals/jama/fullarticle/2761044, I approached the coronavirus treatment problem with "data science" (Natural Language Processing). Instead of looking for cures, I looked for symptoms to find a disease similar to COVID-19, applying natural language processing.
After entering the symptoms, my study reveals the NTM (Pulmonary nontuberculous mycobacterial) disease. NTM is a relatively rare disorder and therefore, I assume that many medical practitioners do not immediately draw this analogy.
NTM reveals almost the same symptoms as compared to later-stage symptoms after a coronavirus infection (including ground-glass opacities on CT scans).
Even if it is not 100% analog, maybe the treatments that cure NTM also cure COVID-19 (e. g. rifamycin, rifabutin, rifampin). Therefore I have included a link with treatment options for the NTM disease.
BTW: It would take me some time to prepare these findings for a journal contribution. Therefore, I want to discuss it here in advance.
Any feedback is welcome!
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I think the latent tuberculosis infection (LTI), being inherent in a huge, several billion subpopulation of patients, rather than BCG vaccination, which is, in fact, only a simple marker of this subpopulation of the LTI patients, could create specific intrapulmonary metabolic conditions capable of protecting the patients against coronavirus infection. It is possible that these LTI-induced specific metabolic conditions are spontaneously created due to the LTI patient's constant chronic exposure to the low-concentration gaseous, and also partially mucus-dissolved ammonia, that is normally intrapulmonary produced by urease-positive mycobacterium tuberculosis. If this hypothesis of mine is correct, then the use of anti-TB agents for the prevention and treatment of COVID-19 pneumonia could be counterproductive. At the same time, the use of inhalations of very low-concentration gaseous, slightly immunosuppressive ammonia or the use of inhalations of aerosolized urea in the prevention and treatment of COVID-19 could be an alternative and more correct solution to the problem. Thus, preexisting latent TB infection, rather than BCG vaccination, may explain the lower morbidity and mortality observed in this extremely large subpopulation of patients who received BCG vaccination during their neonatal period.
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Dear,
In the preparations for publishing a manuscript, we have a big argument about the proper analysis of variance to compare multiple groups for a certain staining quantification.
We have two proteins (A and B) we know that they significantly promote a third protein (C) staining when they are added as a mixture than when they are added as individual proteins due to the effect of these two protein interactions (A & B) with each other which results in a conformational change in protein B. And we know that protein C does not interact with B, but it does interact with A.
Any way, now what we want to analyze is the change in protein A and B functions in the mixture if we remove a certain post-translational modification that occurs in protein A and in protein B as well. To remove that certain post-translational modification, we need to treat the proteins with X enzyme. One issue is that we cannot heat inactivate X enzyme after incubation with either proteins. Thus, when we added the protein mixtures either both treated or one of them treated to compare to the untreated mixture, we had the enzyme there and we included the protein buffer control with the enzyme added to make sure that the effect on protein C staining comes from removing the post-translational modification, not from the remained enzyme with the added proteins to cell cultures.
Now, we have a dataset which has been arranged based on the independent variables in a way to analyze the differentiation in protein C staining (dependent) between the dataset groups. I am very convinced that we do not have in the given dataset a proper/consistent classification for any subcatagories in this dataset to analyze suitable for two-way anova. To me, the dataset are suitable for one-way anova if we consider the protein mixture as one protein (one variable) wither treated or not; otherwise, three-way anova if we consider each protein as a different variable when each is either treated or not. The images below are for the same dataset but with different variable arrangements on the datasheets.
Please, inspire me.
Thank you
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Hi Hana,
If you want to indicate the absence or presence of protein as another factor, then you need to add one more column ("protein presence") and indicate ("yes" / "no"). In this case, you will really get a four-way anova.
From my humble experience, you have very small sample sizes for the analysis. For a qualitative analysis, there is simply not enough statistical power and there is a high risk of making a type 2 error... Try to increase the sample size (to calculate the optimal value, a power analysis must be performed).
Kind regards,
Michael
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Can the use of natural products be an essential therapeutic option in the treatment of COVID-19?
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Dear all, natural products affect viruses indirectly as they are boosting the immune system, with few exceptions such as if I remember well the lotus flower which attacks directly viruses. My Regards
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With the end of the year, we wish a happy life for everyone and the end of the Corona pandemic soon. When is life expected to return to normal before the Corona pandemic?
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Am inclined to say that life was not normal before the virus.
I mean here excessive globalization (wage-dumping) and neoclassics (fiat financing), but also the exponential world travel statistics (1, 5 Billion arrivals in 2018). We need a more human-species appropriate lifestyle, without abolishing the global market economy.
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The clinical treatment of COVID-19 infected individuals.
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I hope this
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We are going to use CSL as a cost-effective nitrogen source for Lactobacillus fermentation in pH 6.3. We have examined the acid treatment method to lower the pH of CSL to 3.5; after that, we centrifuged it to extract the precipitant. The problem is that when we added NaOH to adjust the pH to the optimum level of 6.3 (before or after autoclave) much more weight of precipitant formed. The situation got worse when it becomes mixed with the base culture medium. As long as our aimed product is the biomass, it is vital to remove or reduce the amount of precipitant. Have you tested any method for treating the CSL?
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You can always try centrifugation or filtration after setting up the pH to 6.5 to 6.8. The supernatant you can sterilize before adding it int he final media.
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Dear colleagues,
I am making some teaching notes for my students about wastewater treatment. I wish if some one can send me a soft copy of Metcalf & Eddy book (text can be copied). I already bought the hard copy book, but cant buy a soft copy at the time being.
I really appreciate your support and I promise to buy my own copy in the future.
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Dear friend
find below link to download your book.
password---- sam1234
link
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Dear scientists,
When should we have sham in mtt assay?
What is the sham dose?
How should we use its data for mtt assay analysis?
I heard that if my drug solvent is PBS should take a dose of it and add to my cells like control, is it correct?
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You're welcome. Yes, it doesn't matter what your solvent is, you just want to do everything the same to have a comparison of 'cells treated only with solvent'.
Good luck! Kind regards,
Jasper
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The situation is going worse and the health system in IRAQ is so poor to provide the simplest treatment needs of patients. What should we do in such a horrible situation?
Is there advice that should we follow to stay safe and healthy until they come up with the vaccine of COVID-19.
How to make our immunity stronger in this situation, what should we eat? what should we drink? what kind of medicine should we have to have at home?
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Do you support the tourist openness announced by some countries, knowing that the world has not yet found an effective treatment or vaccine?
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Tourism is very important for economy of my country, but in this moment it is still dangerous. I only support partially, in delimited areas of some regions, with low risks and tight control.
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Recently, many countries along with Bangladesh, producing Remidesivir in mass scale and using in COVID-19 treatment. But best of my knowledge, the remedy has some contradictions when it comes to older patients with critical heart condition and comorbidities.
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Hi
Please check the following link. I believe it will help you.
Regards
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The many referenced sources indicate the modulation of key cell-signaling pathways were effective in controlling the SARS-CoV infection. The same are as follows:
1- Targeting coronaviral replication and cellular JAK2 mediated dominant NF-κB activation for comprehensive and ultimate inhibition of coronaviral activity. Sci Rep 2017;7:1–13. doi:10.1038/s41598-017-04203-9.
2- Severe acute respiratory syndrome Coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3‐dependent ubiquitination of ASC. FASEB J 2019;33(8):8865–8877. doi:10.1096/ fsb2.v33.810.1096/fj.201802418R.
3-Inhibition of NF- kB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival. J Virol 2014;88:913–924. doi:10.1128/jvi.02576-13.
In reference to these published work, one may perform the experimental work using the strategies recently published in Medical Hypotheses Journal entitled " Serum albumin-mediated strategy for the effective targeting of SARS-CoV-2".
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Some articles have been reported pointing out that inhibiting the pro-inflammatory cytokine signalling pathways could be a very promising path. However, in my understanding, JAK or STAT3 inhibitors may not be as selective and interfere with the classic signalling of IL-6 (anti-inflammatory activity). However, antagonists of the trans-signalling of the soluble form of the interleukin sIL-6R, such as the monoclonal antibody Tocilizumab, have high selectivity in modulating only the trans-signalling. Currently, some isolated and non-randomized clinical tests have been published, indicating a great potential for the remission of symptoms of COVID-19.
Non-randomized clinical tests with Tocilizumab:
Mechanism of pharmacological action of Tocilizumab:
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Do you think there may be a benefit from convalescent plasma, ie a blood donation with antibodies from someone who has had COVID19 and recovered?
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We have recently diagnosed a patient as lymphangioleiomyomatosis. She had a giant abdominal angiomyolipoma and mild lung involvement. She underwent surgery for the angiomyolipoma, and we confirmed her diagnosis with a surgical lung biopsy.
We planned to start sirolimus treatment. But the patient wants to get pregnant. What do you think is the best time? Now, before the treatment, or should we wait for treatment and get a good response?
We're in a dilemma. What if the patient gets pregnant now, and respiratory function gets worse during pregnancy? Or what if her respiratory function worsened and she lost the chance to get pregnant?
Any comment is welcome, primarily based on experience or existing literature.
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We also offered treatment to the patient. It is of course not possible to guarantee that the treatment will be beneficial. Concerning the worse during the treatment and the chance of pregnancy may decrease, the patient stated that she wants to get pregnant first and then receive treatment. I think it is necessary to respect the patient's decision.
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Hey,
as the title says I'm looking for a logistic regression with repeated measuring. what I found was a generalized estimates equation (gee), which seems to be limited to a large sample size. But there are authors how claim, that a small sample is possible too, like: http://onlinelibrary.wiley.com/doi/10.1002/sim.6817/epdf, they developed a packet for r, called: geesmv. Is that the way you would do it too? Or is there another way? 
As the title says this is for a forensic sample, we are obtaining risk levels for violence offenders who are already in treatment and we'd like to test if a given risklevel (before treatment) increases the probability for an offender to get into the treatment. 
Samplesize per group will bei arround 30-35. We planning of having n = 70 total
Times measured: k = 2
This is for an expose, so we haven't got the data yet.
Thanks,
m
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For logistic regression analysis a bigger sample size is recommended:
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Talking about RGPFs, Media and backwash costs are the key capital and operational expenditure, respectively.
RGPFs' backwash cost could be minimized by decreasing backwash frequency, i.e. extending run length.
On the other hand, media replacement cost could be minimized by increasing backwash frequency to avoid formation of irremovable dirt layer around the media grains.
To minimize process TOTEX, understanding the mathematical inverse relationship between "backwash frequency" and "media replacement frequency" seems the key? Do you any long-term study about this topic?
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Water is the secret of life, but as a result of pollution has become one of the causes of death and this needs strategies to purify the water from impurities and sterilization in order to be accessible to everyone.
Greetings
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Cheers everybody,
I am completely naive with cells, and I have a question. We would like to evaluate the reactivity of a specific protein, and it seems like that is quite more reactive in an alkaline environment. What could be possible to add to create a sort of physiological alkaline environment? And mostly, it would be possible at all without impairing the cells?
Thank you for your help!
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By improving the environment in which cells are present
Greetings
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Some articles mentioned the addition of ethephon or ethrel solution first into ethanol or Tween 20 solution (also adjusted the particular pH) and then used this solution for post-harvest treatment. While, others mentioned the direct addition of ethephon or ethrel solution into the distilled water and used this solution as post-harvest treatment by dipping the subjected fruits for a specific time.
Which method is effective ? or on what basis we can differentiate these methods ?
Looking forward for expert feedback, Thanks.
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Noted...! Sir Paul Reed Hepperly
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I have treated my highly contaminated water to make it soft but although i managed to make it soft water, the TDS is still the same as i used Cations Exchange Method.
So, Is there any method to reduce the TDS of the contaminated water?
Suggestions would be highly appreciable!
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Reverse Osmosis, and Ion Exchange Treatment.
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Hi everybody,
I'm treating my contaminated cell cultures by primocin. What experiences do you have? What is the optimal length of treatment to obtain healthy cell culture? Do you use primocin all the time as preventive step or only in the case of contamination? 
Thanks a lot
Pavla
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Routine use of antibiotics in cell culture is not recommended. since , antibiotic resistant strains may develop and may cause resistant cryptic infections such as mycoplasma. Moreover, some antibiotics may have effects in cellular functions. Otherwise, primocin is a good choice.
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Upon my research in different textbooks and articles, I figured out that industires including dyeing procedures and paper production produce non-biodegradable wastewater. But I could not find a definite list or inventory of industries clearly stating the biodegredability of their production effluent or wastewater. A reply to this question will also shed light to questions such as whether industries dealing with all types of metals or mines produce non-biodegredable effluents or not.
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Bayan Hussien you are right
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To fight the disease effectively, researchers from across the scientific spectrum and beyond must join forces.
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Yes
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A neat and smooth way of life, avoiding the acquisition of inadequate health habits, as well as certain foodstuffs, and the sensitivity which can be a cause of neurological disease, including MS, may also be cure for the disease
Such a macrobiotic diet, and low radioactive water (cca 6 Becquerel / Bq) lower temperatures (18-20° C), swimming pool and professionally indicated and controlled use of corticosteroids, symptomatic therapy and immunomodulatory drugs in different phases of the disease, proved to be very useful in many cases the form of RR MS, as evidenced by reports of many research papers, observations, the patients themselves and their medical practitioners.
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valuable contribution
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Steatosis , occurs in more than 50% of patients with chronic hepatitis C, that is related to visceral adiposity and obesity. Moreover, Weight loss in patients with chronic hepatitis C may be associated with a reduction in steatosis and abnormal liver enzymes and an improvement in fibrosis. So my question May weight reduction provide a proper response for treatment of patients with chronic C ?
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Hi,
The following article might answer your query
Impact of Obesity on Treatment of Chronic Hepatitis C . HEPATOLOGY 2006;43:1177-1186.
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Can Metformin use as a medicine for breast cancer?
What are the advantages and disadvantages of using Metformin in patients with breast cancer?
Is it possible to use Metformin for both diabetes mellitus and breast cancer?
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There is no known medication or therapeutic technique that is able to completely prevent malignancies, oral or otherwise. Anyone who claims that metformin completely prevents Breast cancer is either a misinformed medical lay person, or a quack practitioner.
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I want to know when rate of application special kind of treatment started and how much studies exctlly are done on this matter . Actually is there any website to show rate of publication about number of studies on tendency toward special treatment?
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Sheyda Darouie thanks for your suggestion,i did it and it was really helpful
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Have a nice day colleague
i'm going to determine pyruvate concentration from cell line suspension (before and after treatment) for different duration times using Elabscience pyruvate assay kit ELISA assay reader. the issue i forced the kit recommended using serum/ plasma /tissue samples, could i use it for cell line ??
thanks in advance
greetings
Zaynab
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There are 2 matters to consider:
(1) Is the kit sensitive enough? The stated sensitivity is 0.006 μmol/mL. Do you think that you can prepare samples that will have at least this concentration of pyruvate?
(2) Do your samples cause interference? I suspect that a kit that can be used for serum and tissue samples will not be bothered by cell line suspensions, which are cleaner samples than tissue homogenates. Make sure you homogenize the cells well enough to release the pyruvate, and clarify the homogenate by centrifugation, as recommended in the kit instructions.
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Dear all,
are there any research gaps in the field of attachment, mentalization, trauma, art therapy that could be investigated in a phd study?
Best, Natalia
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Natalia,
Excellent question. Broad questions elicit a variety of responses some of which may intrigue your curiosity. It takes a lot of curiousity to complete doctoral research.
Part of the endeavor would be to take mentalization deeper in toddlerhood
In my clinical work I find very early disturbance in the sense of self underlies development of a false-self that eventually becomes a self-defeating pattern which often locks PTSD symptoms into the Ego. That is how the trauma is personalized.
An example, a combat veteran found that he had taken in a sense of self as "damn fool." He was the youngest child of 6 and had ample opportunity to experience himself as less capable than his older siblings. This developed a need to gain mastery over being seen as "damn fool." Eventually this became a self-defeating pattern in his childhood and through adulthood.
[In a therapy program I developed, the patients use art to respond to questions about theri relation ships during life transitions across their lifespan. Through collaborative analysis of their drawings, we discover repeated patterns that we explore to understand the underlying sense of self that usually developed first before age 6. So, the art in this program opens possibilities for insight but otherwise is a vehcile to treatment, not treatment itself.]
Once the above patient was well over his sense of self as "damn fool," three traumatic events that plagued him for more than four decades were easily treated with exposure therapy. The incidents were effectively disconnected from his sense of false-self, so the trauma became separate from his experience of himself, allowing them to be processed as separate from him.
When we reviewed each incident, the patient discovered "damn fool" was salient and intagral to each incident. In one he thought he had made a damn fool mistake, in the other two, another person behaved as a "damn fool."
Hopefully, that may stimulate some thoughts of your own as you refine your question.
Journey on
Will
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We often use soft agar colony formation assay to test cancer cells' Anchorage-independent growth as a hallmark of carcinogenesis, the assay described by "Stanley Borowicz, et. al.".
Yet, I can find no detailed evidence of how to use such assay for cancer cells' transformation response to specific treatments.
Do you know of the best timing to include the treatment for such experiment?
Can I include the treatment in the upper agar/cells layer mix from the beginning?
OR
Should I keep fortifying the surface with treatment during the whole 20+ days duration of the experiment?
OR
Should pre-treatment of cells can be the best option, prior starting the soft agar colony formation assay?
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For technical ease, and to ensure that you treatment reaches the cells properly, I would suggest you start by doing a pre-treatment prior to embedding in soft agar. Good luck!
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I have rapid light curve data (ETR for each PAR value) for 24 different specimen of macroalgae. The dataset has three factors: species (species 1 and species 2), pH treatment (treatment 1 and treatment 2) and Day (day 1 of the experiment and day 8 of the experiment). 
I have fitted a model defined by Webb 1974 to 8 subsets of the data:
species 1,pH treatment 1, day 1
species 1, pH treatment 1, day 8
species 1, pH treatment 2, day 1...etc.
I have plotted the curves of the data that is predicted by the model. The model also gives the values and standard error of two parameters: alpha (the slope of the curve) and Ek (the light saturation coefficient). I have added an image of the scatterplot + 4 curves predicted by the model for species 1 (so each curve has a different combination of  the factors pH treatment and Day). 
I was wondering what the best way would be to statistically test if the 8 curves differ from each other? (or in other words: how to test if the slopes and Ek of the models are significantly different?). When googling for answers, I found many ways to check which models with your data better, but not how to test if the different treatments also cause differences in rapid light curves.  
Any help would be greatly appreciated.
Cheers,
Luna
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Although the question is few years old, I’ll add an answer just in case someone finds this relevant.
For comparing between treatments, you need to fit single curve for each individual light curve measured, not a single curve for a treatment, as your graph above implies. Then you can extract the parameters for all the curves and compare these between the treatments, as suggested by Denis.
There is a nice R package called “phytotools” (Silsbe & Malkin 2015) which I have used and found very convenient. It has four different light curve models: Eilers & Peeters 1988, Jassby & Platt 1976, Platt, Gallegos & Harrison 1980 and Webb et al. 1974. The manual also provides the equations for the models.
As the functions for fitting are provided in the package, fitting the light curves is straightforward. The package has basic programming examples also. One needs to do a bit of coding to loop through the data containing the curves and fitting a model. Each of the measured light curves needs to have a unique id. When looping through the ids, you need to extract the parameters (e.g. alpha, beta, so on) from the model fitted, along with the info of your treatments for that particular curve into a data frame.
After this it should be easy to perform the analyses e.g. with ANOVA or something else, depending whether your data shows heterogeneity etc...
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We are conducting a meta-analysis on the effect of mindset interventions (i.e., implicit theory interventions; Blackwell, Trzesniewski, & Dweck, 2007) on academic achievement. We are asking for any data you may have relevant to this topic where:
1. The study administered a mindset/implicit theory intervention directly to students;
2. The study included a comparison group (active control group, passive control group, fixed mindset/entity theory treatment comparison);
3. The study measured academic achievement (e.g., grade in a class, exam grade, GPA or performance on a standardized test) of those who participated in the intervention/were assigned to the comparison group following the intervention.
We aim to be exhaustive, so please send us any paper or results that you think may fit the criteria, including posters, spreadsheets, manuscript drafts, papers in press, dissertations, theses, etc. If you are willing to share your unpublished results or data file (whichever is more convenient for you), we would be grateful if you would send it in any form to burgoyn4@msu.edu
Thank you very much for your time and contribution.
Sincerely,
Alexander Burgoyne, MA
Department of Psychology
Michigan State University
Brooke Macnamara, PhD
Department of Psychological Sciences
Case Western Reserve University
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Thanks for your reply, Yunier Soca Hernández . Do you have any articles or datasets on mindset interventions? Best wishes, Alex
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The God created Nature which has Amazing Powerful Health Benefits and can treat all diseases.
Clean Nature: Waterfalls, Mountains, Thunderstorm, Rain, Forest, contains the High Concentration of NEGATIVE IONS.
As the main cause of all diseases are Positive Ions inducing Decreased Oxygen Utilization-Acidity-Inflammation, using Negative Ions from the Nature and from multiples commercialised Negative Ions (Anion) products will reverse, restore the body damage by changing the body pH from acid to alkaline, increase Oxygen utilization by breaking the agglutinated red cells and restoring their forms, so each red cell will carry oxygen and pass everywhere through tiny capillaries revitalizing the body organs and functions.
Negative Ions are disliked by Evil Jinn (Shaytan, Satan, Demon) and can be used to diagnose the Jinn (Demonic) possession, which can be done by patient, his family, inexperienced medical professional as in this case the medicine is powerless and the treatment is ONLY by RUQYA, Allah's words.
It will save time, money, energy, health, life.
The question: Are the Jinn, created from smokeless fire (Quran 55:15), plasmabeast creatures from the Sun Plasma Inferior, from infrared end of the electromagnetic spectrum (http://www.irfi.org/articles/articles_1_50/jinn_a_scientific_analysis.htm) contain more Positive Ions?
Whatever the treatment (Medical, Negative Ions, Ruqya) the cure is ONLY by Allah. Allah created the Heaven and the Earth and all between and under.
The knowledge is coming only from Allah.
Today, converted to Islam 18 months ago (after being atheist whole life, I will tell:,
RUQYA is the ONLY ONE protection against all diseases and any calamity
RUQYA and Dua are the POWERFULL WEAPON against infections, cancer, diseases, infertility created or no by Jinn (Black Magic, Jinn Possession, Evil Eye) and should be done as the first line treatment if the doctor cares about his patient.
RUQYA doesn't require any skills (should be done by patient or family), it is the recitation of the certain surahs from the Noble Quran, it is the action with intention (to be cured and protected) but it is under conditions (faith in Allah etc).
Turning to Allah, our Creator, Protector, Sustainer, Nourisher, Preserver, Disposer of all affairs, Allah will not only protect you from all calamities, but also will facilitate your life, you will be successful and, the most important, will guide you to the strait path to the Eternal life in Paradise
Dr Mira Bajirova
Assistant Professor
Consultant IVF, Ob-Gyn (Paris)
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Since there are long term treatments for some diseases or many type of cancers not knowing how to be treated, im wondering how brain activity can ever control the disease.
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Positivity (positive attitude) leads to the hope of improving the disease and in my opinion it really accelerate the speed of recovery from a disease.
For curing cancer pranayam (breathing practices) and meditation are really beneficial.
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Probably this will be the future. In the meantime we are overlooking very simple non taylored treatments that are less toxic and almost as effective that the sofisticated ones.
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The venom contains MP1 molecule.
MP1 molecule and lipid membrane.
The potential of MP1 molecule as cancer drug.
Combination therapies.
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Ya its very true Polybia-MP1 (MP1 extracted from the venom of Brazilian wasp Polybia paulista) have anticancer potential I have also published this in review article recently.
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Although thousands of scientists and specialists around the world are working on different types of cancer to find certain treatment for them, There is no definite way to cure that and we lose our relatives and friends every day. So what is the most important and challenging property of cancer that stands in front of us?
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Cancer has been around since the dinosaurs and, being caused by haywire genes, the risk is hardwired into all of us. The longer we live, the more likely something might go wrong, in any number of ways. For cancer is a living thing – ever-evolving to survive.
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  • Short stature is one of the problems that some people experience, and people are looking for a solution to this problem.
  • its been known that there are several hormonal treatments
  • I am interested in knowing whether it helps to grow people's height by stimulating the magnetic field of bone cells without using hormonal drugs.
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There are two forms to apply the magnetic field, one is DC field which only acts on magnetic substances as hemoglobin of the blood, but I don't see that there are any special ferromagnetic substance in the bones.
The other kind of field AC to apply with frequency and that is much more difficult to know its effects because it can acts on many different substances due to Faraday's law. But if this were the case, it would be necessary to know quite well the frequency effect on the bone's growth cells (for instance, a resonance) or their associated mechanisms.
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I got similar results for acute and chronic treatments which applied in different doses. How this similarity can be explained?!
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Here is a potential set of interpretations based on the information you have provided:
1. Both treatments elicit the same placebo response.
2. Both treatments have the same efficacy at the doses used.
3. Dosage1 treatment and Dosage2 treatment come from different bottles with different expiration dates.
Dennis
Dennis Mazur
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In most diseases with no cure or long-term treatment, there are different shortages in the body from our brain's function to lack of Nutrients. Maybe we can stimulate particular parts of patient's brain to act differently and control the body to fight better with illness.
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Few years ago the scientists from the Department of Psychiatry Medical University of South Carolina submitted a research paper claiming a similar preposition that electromagnetic stimulation of the frontal lobe of the brain may cause to reduce weight. I received that manuscript for the review from the Medical Journal "Obesity".
My only and key question was that did the researchers take into an account the subNucleus load of the neuroinvasive viral genomes that continually proliferate which in turn. compromise the cellular homeostasis?
Obviously. the answer was no. Therefore, the editor of the journal declined its publication.
Now. EMG stimulation is very hypothetical and cant be used indiscriminately for the whole brain. All neurons not typically dealing with the uniform pathology. Different sections of the control system may be dealing with dendritic molecular change or cellular metabolic challenge or Nucleus or genetic patho-kinetics.
If the frequency of the source becomes intolerable for the brain tissue, of course it will covey more harm to the tissue than favor.
Nucleopathy is a new dimension now leading to best understand the pathophysiology of the brain.
We at the NIDS Treatment & Research Center are Launching this March a New Discipline of Medicine the NUCLEOPATHY.
This will help you understand the origination of all diseases and how to rectify them.
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Hello,
I got two 2x3type ANOVAs. The independent var, the treatment groups and gender division, stayed the same. But I got two different dependent var. Am I able to compare those two dvar somehow?
My first DV is "acceptance", my second one "perceived use". Am I able to compare those 2 ANOVA outcomes somehow or check if there is a correlation?
EDIT: I am using SPSS. Thank you.
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Hi Ben
Cross-sectional or a follow-up study?
Anyhow, you can use regression (linear, since you have a continous dependent variable), but you need to choose one of them as a dependent variable and use the other one as a predictor/independent variable. Look up theory to help you decide.
Best
John-Kåre
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There are many demands for effective use of herbs to cure snake bite patients.
The snake charmers also advocate different roots/ stems for treatment of persons with bite of any poisonous snake.
Is there any research article with animal experimentation of herbs and bite/ poisons of snakes?
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Antibiotics are given to safe guard against secondary bacterial infections due to reduced immunity during viral infections.
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Dear Anthony,
Microbes are already ruling the world, in practically every niche. We have more microbes living in our body than our own signature cells. All multicellular beings are like preserved food of microbes and shall finally be consigned to microbes.
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I tried to generete an Hey1 overexpresion to analyze that treatment in embryonic cells, However I can´t use vectors and I need a solution.
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why it so called
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thanks
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For aluminium alloy
What kind of heat treatments affect grain size?
Which one increase and which one decrease?
Does grain orientation change along with the transformation of grain size?
Thanks for answering
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The addition of grain refiners reduces the grain size. Other than that, cooling rate, inoculation during casting influences the grain size and morphology. Hardening behavior differs for different series of aluminium alloys, some are heat treatable and some or not. It cannot be generalized for all aluminium alloys. Composition also plays an important role. Grain growth is diffusion controlled, the growth of dendrite arm tips are controlled by "growth restriction parameter". So there are multiple factors. 
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How to run interaction between independent variables and treatment (1,0) using  SPSS? knowing that the output has two possibilities only 
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If u want to establish through bivariate analysis i.e. one variable vs. outcome, then Pearson's chi-square is the option. 
But if u want to take all the independent variables together and want to establish the interaction, then Binary Multivariable Logistic Regression analysis is the option, since u have dichotomous categorical variable. Before conducting logistic model, u have go, whether it fulfills all assumptions or not.  
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 1/ Herceptin is used for the treatment of breast cancer
 2/ Herceptin is used for the treatment of cancer characterised by overactivity of the Bcr-Abl gene
 3/ Herceptin is a relatively new form of treatment that helps the immune system recognise cancer cells
4/ Herceptin is the brand name of the drug Trastuzumab.
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1 and 4
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chronic idiopathic urticaria 
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Nonsedating second generation H1 antihistamines (up to 4 times standard dose) ... no experience with onalizumab due to costs. 
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A new treatment will be used to treat only one group and the results will be evaluated... How to set a sample size for such study??
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Preferably, you need a Reference population, e.g., results for those who were treated With the "Old" treatment. There are several online sample size calculators/descriptions for one sample continous variable compared With a Reference mean or CI.
Much better would be improving the design to an RCT and use sample size calculations for two Groups (the old treatment expecatations (Guess you have some data) versus the New treatment (expectations or results from a pilot study).
All the best!!
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material and method used for propolis extraction in treatment of periodontal disease
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Thank you Dr Emil
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22 week pregnant lady with 4,5 cm diameter chorangioma diagnosed by chance. 
Any treatment but monitoring via US , doppler. threat of premature birth 
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you may check "Combined Approach in a Large Placental Chorioangioma Case with Intratumoral Alcohol Injection, Cordocentesis, IU Transfusion, and Amnioreduction"  http://dx.doi.org/10.3109/15513815.2012.659402 
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There are oral ibandronate 100mg and 150mg dosage once-monthly treatment of postmenopausal osteoporosis in Asian patients. Could you please tell which dosage is best option for treat East Asia patients
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Since your question is pertaining to Asian population, these publications may be useful to you:
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A new treatment will be used to treat only one group and the results will be evaluated... How to set a sample size for such study??
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Study design should be defined and sample size can be calculated by the available sample size calculators
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Is there any scientific tool or equation to calculate "Hospital Treatment Capacity". Would you help me please?
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Yes. The government should control drug's toxicity. There is a big law approval problem that no matter how tight the clinical trial for how big of the sample number is. The drug's approval is tested under one single drug is safe at a certain time.
However, a patient's drug can be up to 30 kinds as I know. ER is unlimited use drugs. Once a patient is on the drug, his drug using period is almost lifetime taking and as time passed by, drugs variety is increasing. I attached my patient's drug side effects and my half way treatment result for your reference.
If you want, sampling some hospitals and ask a patient before dying, on average, how long did they staying in the hospital? How many days in average a patient staying in a hospital once a tube is inserted? What is the chance for a patient has organ failure and/or tube insertion? Or, if you can find an answer from the internet.
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What is new about treatment of sciatic nerve pain (sciatica)?
Is there any studies about the effect of physiotherapy like exercises, cupping therapy, Chinese needles, ... etc.
Thanks in advance for your contribution.
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Dear Khaled
It's difficult to answer your question here. So, there is a guideline published by National Clinical Guideline Centre (NICE) in United Kingdom (UK) in 2016. It has been considered to be a reliable source. This guideline may answer your question as it covers all different interventions of low back pain and sciatica. Please find the attached files or you can visit there website: https://www.nice.org.uk/guidance/ng59
Good luck!
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What is the simplest, benchtop way, to find out the proportion of a drug bound to protein in the brain following systemic treatment in vivo?
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Hi Saidhbhe, the most important questions of pharmacokinetics of small drugs are:
1) does the drug bind to serum albumin?,
2) how well does the drug bind to serum albumin?
3) how can we improve the drug binding to serum albumin? 
If a drug does not bind serum albumin, it will be filtered out by the kidneys in minutes and end up in the toilet.
So the simplest benchtop way to see if a drug is a viable candidate is its binding to serum albumin.  It doesn't matter what organ you are looking at. Kidneys effectively filter out anything under 40 kDa. Albumin is ~68 kDa. Stuff bound to albumin stays around. Anything smaller will be filtered and flushed. 
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Arthrodiastasis is a simple and cost-effective method of treatment in ankle and knee arthrosis. Though in my opinion it is underestimated and rarely used among my collegues. I wonder how popular is this method in your hospital/country? What is your experience with this method?
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In the USA there isn't any good long term data to support it.  Some have had OK results but they have not been reproducible.  
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Techniques besides post-fabrication treatment such as magnetic-field annealing.
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Yes, we want to increase the exchange bias field.  Thanks for your suggestions. 
We have tried to change the thickness of the ferromagnetic layer, but our experiments of spin valve fabrication were not well repeated. We are still investigating this issue.
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I'm working with non parametric tests and I need to rank the treatments but I'm not sure if the Duncan's test can be applied. If no tests of this kind exists for non parametric data, what can I do in order to obtain this rank?
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Hi Laith,
Thanks for your answer.
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cloning startagy
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Yes ! It is possible to clone in pCambia vector without AP treatment. Check with the ligation results if AP is really required.
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Hi everybody,
I would like to know what will be the most efficient (+) control to confirm the inhibition of the proteasome in Zebrafish lysate after proteasome inhibitor treatment.
Thanks.
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I want to know from this attach analysed split split plot design file which is the best treatment and how it can be identified ? and how to identify interaction effect ?
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Hi all,
I wonder if there is any statistics about the asparaginase treatment in Iraqi hospitals? 
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Hi everybody!
Do you know what these vacuoles could be?
The cells are primary human skin fibroblasts treated with molecule. Cells do not die from this treatment. Thank you for your help
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They appear more artefactual as mentioned above by Dr Wolfgang. In addition to what he has discussed, I would add another possibility of endocyt