Questions related to Treatment
You can think coating adhesive and then producing packaging tape with the BOPP Film.
Hi everyone,
I am a 3rd-year student at the University Of Bolton studying psychology, psychotherapy and counselling.
My dissertation concerns psychedelics as a mental health treatment and understanding people's journeys.
I would appreciate if you or anyone you know could help me by participating in my study.
My questionnaire can be found at: https://forms.gle/o8qfeGLCifyj4eq19
I appreciate your help with this!
Hello everyone, I'm working on treatment engagement during therapy for my studies. I want to do research on factors influencing (barriers to and facilitators of) treatment engagement (remaining in therapy, being committed and involved in the process) with suicidal adults and I can't find much about this for now. Please can you help me by providing some references?
#suicide #suicidal #treatmentengagement
COVID-19 is mainly a respiratory disease that affects the lung, although other organ structures with endothelium seems to be affected too.
When should we do imaging?
What is the aim of the imaging?
How can it help with management?
Do you agree with the following consensus statement?
How will you adjust your own practice and difficulties encountered? Why?
Ref:
The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society. Chest. 2020 Apr 07.
Dear Researchers,
Preliminary data of various studies showed the proportion of the population from Black (in New York), Asian (UK) and other minority ethnic backgrounds and people from low income are highly deprived with COVID-19. These groups reported higher COVID-19 mortality rates irrespective of population density. Furthermore, most of these minority groups are aged 50-79. Since the epidemic started, several studies have confirmed these findings. It is interesting to discuss the reasons behind these adverse outcomes and also share your experience about COVID-19.
Please contribute to this question with your assured knowledge.
In treating cells for different time spans like 24h, 48h and 72h, should we seed different numbers of the cells suitable for relevant treating time?
If yes, what is the method to define the best seed number?
If not, in the case the cells continue to grow more in higher treatment times (though the viability decrease as drug concentrations increase), does higher treatment time worth to continue studying?
Thanks for your participation.
I'm looking at the effect of the drug on lung function. What test should I perform for pre and post control vs pre and post treatment? Control group had measurements taken before and after recieving placebo and same for the tratment group, however they were administered a drug. Different subjects were used in control and treatment groups.
I'm very thankful for help.
I work in community corrections and the research suggests the Duluth model is innefective at best whjen compared to CBT-type treatments. The question is, are we increasing the risk of DV offending if the perpetrators are mandated to offend?
Since more men and older women contract coronavirus, will it be useful to additionally use estrogen for its treatment or prevention?
I am looking for a recent diagnosis for chikungunya virus through computational biology techniques.
After reading the article in JAMA https://jamanetwork.com/journals/jama/fullarticle/2761044, I approached the coronavirus treatment problem with "data science" (Natural Language Processing). Instead of looking for cures, I looked for symptoms to find a disease similar to COVID-19, applying natural language processing.
After entering the symptoms, my study reveals the NTM (Pulmonary nontuberculous mycobacterial) disease. NTM is a relatively rare disorder and therefore, I assume that many medical practitioners do not immediately draw this analogy.
NTM reveals almost the same symptoms as compared to later-stage symptoms after a coronavirus infection (including ground-glass opacities on CT scans).
Even if it is not 100% analog, maybe the treatments that cure NTM also cure COVID-19 (e. g. rifamycin, rifabutin, rifampin). Therefore I have included a link with treatment options for the NTM disease.
BTW: It would take me some time to prepare these findings for a journal contribution. Therefore, I want to discuss it here in advance.
Any feedback is welcome!
Dear,
In the preparations for publishing a manuscript, we have a big argument about the proper analysis of variance to compare multiple groups for a certain staining quantification.
We have two proteins (A and B) we know that they significantly promote a third protein (C) staining when they are added as a mixture than when they are added as individual proteins due to the effect of these two protein interactions (A & B) with each other which results in a conformational change in protein B. And we know that protein C does not interact with B, but it does interact with A.
Any way, now what we want to analyze is the change in protein A and B functions in the mixture if we remove a certain post-translational modification that occurs in protein A and in protein B as well. To remove that certain post-translational modification, we need to treat the proteins with X enzyme. One issue is that we cannot heat inactivate X enzyme after incubation with either proteins. Thus, when we added the protein mixtures either both treated or one of them treated to compare to the untreated mixture, we had the enzyme there and we included the protein buffer control with the enzyme added to make sure that the effect on protein C staining comes from removing the post-translational modification, not from the remained enzyme with the added proteins to cell cultures.
Now, we have a dataset which has been arranged based on the independent variables in a way to analyze the differentiation in protein C staining (dependent) between the dataset groups. I am very convinced that we do not have in the given dataset a proper/consistent classification for any subcatagories in this dataset to analyze suitable for two-way anova. To me, the dataset are suitable for one-way anova if we consider the protein mixture as one protein (one variable) wither treated or not; otherwise, three-way anova if we consider each protein as a different variable when each is either treated or not. The images below are for the same dataset but with different variable arrangements on the datasheets.
Please, inspire me.
Thank you
Can the use of natural products be an essential therapeutic option in the treatment of COVID-19?
With the end of the year, we wish a happy life for everyone and the end of the Corona pandemic soon. When is life expected to return to normal before the Corona pandemic?
The clinical treatment of COVID-19 infected individuals.
We are going to use CSL as a cost-effective nitrogen source for Lactobacillus fermentation in pH 6.3. We have examined the acid treatment method to lower the pH of CSL to 3.5; after that, we centrifuged it to extract the precipitant. The problem is that when we added NaOH to adjust the pH to the optimum level of 6.3 (before or after autoclave) much more weight of precipitant formed. The situation got worse when it becomes mixed with the base culture medium. As long as our aimed product is the biomass, it is vital to remove or reduce the amount of precipitant. Have you tested any method for treating the CSL?
Dear colleagues,
I am making some teaching notes for my students about wastewater treatment. I wish if some one can send me a soft copy of Metcalf & Eddy book (text can be copied). I already bought the hard copy book, but cant buy a soft copy at the time being.
I really appreciate your support and I promise to buy my own copy in the future.
Dear scientists,
When should we have sham in mtt assay?
What is the sham dose?
How should we use its data for mtt assay analysis?
I heard that if my drug solvent is PBS should take a dose of it and add to my cells like control, is it correct?
The situation is going worse and the health system in IRAQ is so poor to provide the simplest treatment needs of patients. What should we do in such a horrible situation?
Is there advice that should we follow to stay safe and healthy until they come up with the vaccine of COVID-19.
How to make our immunity stronger in this situation, what should we eat? what should we drink? what kind of medicine should we have to have at home?
Do you support the tourist openness announced by some countries, knowing that the world has not yet found an effective treatment or vaccine?
Recently, many countries along with Bangladesh, producing Remidesivir in mass scale and using in COVID-19 treatment. But best of my knowledge, the remedy has some contradictions when it comes to older patients with critical heart condition and comorbidities.
The many referenced sources indicate the modulation of key cell-signaling pathways were effective in controlling the SARS-CoV infection. The same are as follows:
1- Targeting coronaviral replication and cellular JAK2 mediated dominant NF-κB activation for comprehensive and ultimate inhibition of coronaviral activity. Sci Rep 2017;7:1–13. doi:10.1038/s41598-017-04203-9.
2- Severe acute respiratory syndrome Coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3‐dependent ubiquitination of ASC. FASEB J 2019;33(8):8865–8877. doi:10.1096/ fsb2.v33.810.1096/fj.201802418R.
3-Inhibition of NF- kB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival. J Virol 2014;88:913–924. doi:10.1128/jvi.02576-13.
In reference to these published work, one may perform the experimental work using the strategies recently published in Medical Hypotheses Journal entitled " Serum albumin-mediated strategy for the effective targeting of SARS-CoV-2".
Do you think there may be a benefit from convalescent plasma, ie a blood donation with antibodies from someone who has had COVID19 and recovered?
We have recently diagnosed a patient as lymphangioleiomyomatosis. She had a giant abdominal angiomyolipoma and mild lung involvement. She underwent surgery for the angiomyolipoma, and we confirmed her diagnosis with a surgical lung biopsy.
We planned to start sirolimus treatment. But the patient wants to get pregnant. What do you think is the best time? Now, before the treatment, or should we wait for treatment and get a good response?
We're in a dilemma. What if the patient gets pregnant now, and respiratory function gets worse during pregnancy? Or what if her respiratory function worsened and she lost the chance to get pregnant?
Any comment is welcome, primarily based on experience or existing literature.
Hey,
as the title says I'm looking for a logistic regression with repeated measuring. what I found was a generalized estimates equation (gee), which seems to be limited to a large sample size. But there are authors how claim, that a small sample is possible too, like: http://onlinelibrary.wiley.com/doi/10.1002/sim.6817/epdf, they developed a packet for r, called: geesmv. Is that the way you would do it too? Or is there another way?
As the title says this is for a forensic sample, we are obtaining risk levels for violence offenders who are already in treatment and we'd like to test if a given risklevel (before treatment) increases the probability for an offender to get into the treatment.
Samplesize per group will bei arround 30-35. We planning of having n = 70 total
Times measured: k = 2
This is for an expose, so we haven't got the data yet.
Thanks,
m
Talking about RGPFs, Media and backwash costs are the key capital and operational expenditure, respectively.
RGPFs' backwash cost could be minimized by decreasing backwash frequency, i.e. extending run length.
On the other hand, media replacement cost could be minimized by increasing backwash frequency to avoid formation of irremovable dirt layer around the media grains.
To minimize process TOTEX, understanding the mathematical inverse relationship between "backwash frequency" and "media replacement frequency" seems the key? Do you any long-term study about this topic?
Cheers everybody,
I am completely naive with cells, and I have a question. We would like to evaluate the reactivity of a specific protein, and it seems like that is quite more reactive in an alkaline environment. What could be possible to add to create a sort of physiological alkaline environment? And mostly, it would be possible at all without impairing the cells?
Thank you for your help!
Some articles mentioned the addition of ethephon or ethrel solution first into ethanol or Tween 20 solution (also adjusted the particular pH) and then used this solution for post-harvest treatment. While, others mentioned the direct addition of ethephon or ethrel solution into the distilled water and used this solution as post-harvest treatment by dipping the subjected fruits for a specific time.
Which method is effective ? or on what basis we can differentiate these methods ?
Looking forward for expert feedback, Thanks.
I have treated my highly contaminated water to make it soft but although i managed to make it soft water, the TDS is still the same as i used Cations Exchange Method.
So, Is there any method to reduce the TDS of the contaminated water?
Suggestions would be highly appreciable!
Hi everybody,
I'm treating my contaminated cell cultures by primocin. What experiences do you have? What is the optimal length of treatment to obtain healthy cell culture? Do you use primocin all the time as preventive step or only in the case of contamination?
Thanks a lot
Pavla
Upon my research in different textbooks and articles, I figured out that industires including dyeing procedures and paper production produce non-biodegradable wastewater. But I could not find a definite list or inventory of industries clearly stating the biodegredability of their production effluent or wastewater. A reply to this question will also shed light to questions such as whether industries dealing with all types of metals or mines produce non-biodegredable effluents or not.
To fight the disease effectively, researchers from across the scientific spectrum and beyond must join forces.
A neat and smooth way of life, avoiding the acquisition of inadequate health habits, as well as certain foodstuffs, and the sensitivity which can be a cause of neurological disease, including MS, may also be cure for the disease
Such a macrobiotic diet, and low radioactive water (cca 6 Becquerel / Bq) lower temperatures (18-20° C), swimming pool and professionally indicated and controlled use of corticosteroids, symptomatic therapy and immunomodulatory drugs in different phases of the disease, proved to be very useful in many cases the form of RR MS, as evidenced by reports of many research papers, observations, the patients themselves and their medical practitioners.
Steatosis , occurs in more than 50% of patients with chronic hepatitis C, that is related to visceral adiposity and obesity. Moreover, Weight loss in patients with chronic hepatitis C may be associated with a reduction in steatosis and abnormal liver enzymes and an improvement in fibrosis. So my question May weight reduction provide a proper response for treatment of patients with chronic C ?
Can Metformin use as a medicine for breast cancer?
What are the advantages and disadvantages of using Metformin in patients with breast cancer?
Is it possible to use Metformin for both diabetes mellitus and breast cancer?
I want to know when rate of application special kind of treatment started and how much studies exctlly are done on this matter . Actually is there any website to show rate of publication about number of studies on tendency toward special treatment?
Have a nice day colleague
i'm going to determine pyruvate concentration from cell line suspension (before and after treatment) for different duration times using Elabscience pyruvate assay kit ELISA assay reader. the issue i forced the kit recommended using serum/ plasma /tissue samples, could i use it for cell line ??
thanks in advance
greetings
Zaynab
Dear all,
are there any research gaps in the field of attachment, mentalization, trauma, art therapy that could be investigated in a phd study?
Best, Natalia
We often use soft agar colony formation assay to test cancer cells' Anchorage-independent growth as a hallmark of carcinogenesis, the assay described by "Stanley Borowicz, et. al.".
Yet, I can find no detailed evidence of how to use such assay for cancer cells' transformation response to specific treatments.
Do you know of the best timing to include the treatment for such experiment?
Can I include the treatment in the upper agar/cells layer mix from the beginning?
OR
Should I keep fortifying the surface with treatment during the whole 20+ days duration of the experiment?
OR
Should pre-treatment of cells can be the best option, prior starting the soft agar colony formation assay?
I have rapid light curve data (ETR for each PAR value) for 24 different specimen of macroalgae. The dataset has three factors: species (species 1 and species 2), pH treatment (treatment 1 and treatment 2) and Day (day 1 of the experiment and day 8 of the experiment).
I have fitted a model defined by Webb 1974 to 8 subsets of the data:
species 1,pH treatment 1, day 1
species 1, pH treatment 1, day 8
species 1, pH treatment 2, day 1...etc.
I have plotted the curves of the data that is predicted by the model. The model also gives the values and standard error of two parameters: alpha (the slope of the curve) and Ek (the light saturation coefficient). I have added an image of the scatterplot + 4 curves predicted by the model for species 1 (so each curve has a different combination of the factors pH treatment and Day).
I was wondering what the best way would be to statistically test if the 8 curves differ from each other? (or in other words: how to test if the slopes and Ek of the models are significantly different?). When googling for answers, I found many ways to check which models with your data better, but not how to test if the different treatments also cause differences in rapid light curves.
Any help would be greatly appreciated.
Cheers,
Luna
We are conducting a meta-analysis on the effect of mindset interventions (i.e., implicit theory interventions; Blackwell, Trzesniewski, & Dweck, 2007) on academic achievement. We are asking for any data you may have relevant to this topic where:
1. The study administered a mindset/implicit theory intervention directly to students;
2. The study included a comparison group (active control group, passive control group, fixed mindset/entity theory treatment comparison);
3. The study measured academic achievement (e.g., grade in a class, exam grade, GPA or performance on a standardized test) of those who participated in the intervention/were assigned to the comparison group following the intervention.
We aim to be exhaustive, so please send us any paper or results that you think may fit the criteria, including posters, spreadsheets, manuscript drafts, papers in press, dissertations, theses, etc. If you are willing to share your unpublished results or data file (whichever is more convenient for you), we would be grateful if you would send it in any form to burgoyn4@msu.edu.
Thank you very much for your time and contribution.
Sincerely,
Alexander Burgoyne, MA
Department of Psychology
Michigan State University
Brooke Macnamara, PhD
Department of Psychological Sciences
Case Western Reserve University
Since there are long term treatments for some diseases or many type of cancers not knowing how to be treated, im wondering how brain activity can ever control the disease.
The venom contains MP1 molecule.
MP1 molecule and lipid membrane.
The potential of MP1 molecule as cancer drug.
Combination therapies.
Although thousands of scientists and specialists around the world are working on different types of cancer to find certain treatment for them, There is no definite way to cure that and we lose our relatives and friends every day. So what is the most important and challenging property of cancer that stands in front of us?
- Short stature is one of the problems that some people experience, and people are looking for a solution to this problem.
- its been known that there are several hormonal treatments
- I am interested in knowing whether it helps to grow people's height by stimulating the magnetic field of bone cells without using hormonal drugs.
I got similar results for acute and chronic treatments which applied in different doses. How this similarity can be explained?!
In most diseases with no cure or long-term treatment, there are different shortages in the body from our brain's function to lack of Nutrients. Maybe we can stimulate particular parts of patient's brain to act differently and control the body to fight better with illness.
Hello,
I got two 2x3type ANOVAs. The independent var, the treatment groups and gender division, stayed the same. But I got two different dependent var. Am I able to compare those two dvar somehow?
My first DV is "acceptance", my second one "perceived use". Am I able to compare those 2 ANOVA outcomes somehow or check if there is a correlation?
EDIT: I am using SPSS. Thank you.
There are many demands for effective use of herbs to cure snake bite patients.
The snake charmers also advocate different roots/ stems for treatment of persons with bite of any poisonous snake.
Is there any research article with animal experimentation of herbs and bite/ poisons of snakes?
Antibiotics are given to safe guard against secondary bacterial infections due to reduced immunity during viral infections.
I tried to generete an Hey1 overexpresion to analyze that treatment in embryonic cells, However I can´t use vectors and I need a solution.
For aluminium alloy
What kind of heat treatments affect grain size?
Which one increase and which one decrease?
Does grain orientation change along with the transformation of grain size?
Thanks for answering
How to run interaction between independent variables and treatment (1,0) using SPSS? knowing that the output has two possibilities only
1/ Herceptin is used for the treatment of breast cancer
2/ Herceptin is used for the treatment of cancer characterised by overactivity of the Bcr-Abl gene
3/ Herceptin is a relatively new form of treatment that helps the immune system recognise cancer cells
4/ Herceptin is the brand name of the drug Trastuzumab.
A new treatment will be used to treat only one group and the results will be evaluated... How to set a sample size for such study??
material and method used for propolis extraction in treatment of periodontal disease
22 week pregnant lady with 4,5 cm diameter chorangioma diagnosed by chance.
Any treatment but monitoring via US , doppler. threat of premature birth
There are oral ibandronate 100mg and 150mg dosage once-monthly treatment of postmenopausal osteoporosis in Asian patients. Could you please tell which dosage is best option for treat East Asia patients
A new treatment will be used to treat only one group and the results will be evaluated... How to set a sample size for such study??
Is there any scientific tool or equation to calculate "Hospital Treatment Capacity". Would you help me please?
What is new about treatment of sciatic nerve pain (sciatica)?
Is there any studies about the effect of physiotherapy like exercises, cupping therapy, Chinese needles, ... etc.
Thanks in advance for your contribution.
What is the simplest, benchtop way, to find out the proportion of a drug bound to protein in the brain following systemic treatment in vivo?
Arthrodiastasis is a simple and cost-effective method of treatment in ankle and knee arthrosis. Though in my opinion it is underestimated and rarely used among my collegues. I wonder how popular is this method in your hospital/country? What is your experience with this method?
Techniques besides post-fabrication treatment such as magnetic-field annealing.
I'm working with non parametric tests and I need to rank the treatments but I'm not sure if the Duncan's test can be applied. If no tests of this kind exists for non parametric data, what can I do in order to obtain this rank?
Hi everybody,
I would like to know what will be the most efficient (+) control to confirm the inhibition of the proteasome in Zebrafish lysate after proteasome inhibitor treatment.
Thanks.
I want to know from this attach analysed split split plot design file which is the best treatment and how it can be identified ? and how to identify interaction effect ?
Hi all,
I wonder if there is any statistics about the asparaginase treatment in Iraqi hospitals?
Hi everybody!
Do you know what these vacuoles could be?
The cells are primary human skin fibroblasts treated with molecule. Cells do not die from this treatment. Thank you for your help