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Publications related to Toxicology (10,000)
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Presentation
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Special Issue: In Vivo Toxicological Evaluation of Metal Nanoparticles. Guest editor: Dr. Miroslava Lehotska Mikusova Deadline for manuscript submissions: 31 Marec 2023 See more details at https://lnkd.in/eGvx_zf
Article
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The Rubiaceae family taxonomic classification is complex. Genus Rubia with 70 species belongs to Rubieae tribe of Rubioideae subfamily of the Rubiaceae family. These species have been widely distributed and cultivated around the world, and are mainly concentrated in the tropics. The effects of bioactive metabolites of various parts, particularly ro...
Article
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With the advent of the 20th century, the usage of plastics and the plastic manufacturing industries have risen sharply. Plastics have become an irreplaceable part of our day-today life as most of the gadgets/consumables that we use are made of plastic. The improper disposal and management of plastics have impacted our planet negatively by polluting...
Book
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Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses. This book, Dietary Polyphenols in Human Diseases-Advances and Challenges in Drug Discovery, fills the gap that exists in the current knowledge by presenting the latest informa...
Article
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Background Forensic entomology (FE) is widely considered as an important field of forensic science, particularly in the field of estimating postmortem intervals, which has advanced considerably across the world. Main body Researchers used necrophagous insects in twelve Egyptian governorates to look into the variables that impact insect succession...
Article
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This article reviews the current status of nanotechnology with emphasis on application and related environmental considerations as well as legislation. Application and analysis of nanomaterials in infrastructure (construction, building coatings, and water treatment) is discussed, and in particular nanomaterial release during the lifecycle of these...
Article
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Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be visualized in their native tissues using mass spectrometry imaging. Up to now, the most commonly applied mass spectrometry imaging techniques are matrix assisted laser desorption ionization mass spectrom...
Article
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Behavioural toxicology is an emerging field of ecotoxicology gaining prominence in both aquatic and terrestrial environments. The aim of this work is to review studies investigating the avoidance behaviour of soil invertebrates in contaminated soils. The review begins with an overview of experimental design and abiotic factors that influence soil i...
Article
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The mining process in a coal industry is responsible for a large environmental impact, 60% of the total extracted are discarded and sent to a controlled dam due to its potential toxicological effect when exposed to the environment. On the other hand, polymer consumption has grown at an annual rate of 5%, exceeding 300 million tons/year. Therefore,...
Article
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Being the dietary staple in most Asian countries, the concentrations of toxic and essential element content in rice is an important aspect in terms of both toxicological and nutritional standpoints. This study aimed to analyse trace elements (As, Cd, Pb, Hg, Cr, Ni, Zn, Cu, Mn, Fe, and Mo) in improved, traditional, and imported rice varieties consu...
Article
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This correspondence article provides a response to comments that have been raised regarding the long-range environmental transport of chemical additives associated with microplastic particles and plastic debris, which includes additional clarification for the continuing need for holistic approaches. Recognizing that not all microplastic particles a...
Article
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Background A method is now available to quantify the number of pesticide residues and relative pesticide dietary risks in individual servings of food. The Dietary Risk Index (DRI) system combines the results of United States and United Kingdom pesticide residue testing programs with data on food serving sizes and each pesticide’s chronic Reference...
Article
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The concept of the wholesomeness of irradiated foods and previous studies on their toxicological safety in Europe, the U.S., and Japan over many years are described. In particular, the recent Japanese research on the safety of 2-alkylcyclobutanones (2-ACBs), which are specifically produced from lipids in foods by irradiation, was described in compa...
Article
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Clothianidin (CLO) is an insecticide belonging to the second-generation class of neonicotinoids. In this study, we evaluated how CLO affects the survival and the complete life cycle of the tropical insect Chironomus xanthus, a non-target species, considering the Parental (P) and Filial (F1) generations. We found a 48 h-lethal concentration (LC 50)...
Article
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Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are the latest class of drugs approved to treat type 2 DM (T2DM). Although adverse effects are often caused by a metabolite rather than the drug itself, only the safety assessment of disproportionate drug metabolites is usually performed, which is of particular concern for drugs of chronic use, suc...
Article
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The potential release of metals, especially copper (Cu) during mining of seafloor massive sulphides (SMS), represents a potential toxicological threat to cold-water coral (CWC) habitats. Herein, we evaluated for the first time the response of the whip coral Viminella flagellum to short-term acute Cu exposure. Nubbins of V. flagellum were exposed to...
Article
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Tetracycline, a broad-spectrum antibiotic, is a widely used pharmaceutical agent for treating common infections in humans and animals. Because of its indiscriminate overuse, tetracycline remains one of the most persistent micro-pollutants in the environment. This study explored magnetized cotton dust biochar (MCDB) and magnetized cotton dust (MCD)...
Article
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Micro and nanoplastics (MNPLs) are emergent environmental pollutants requiring urgent information on their potential risks to human health. One of the problems associated with the evaluation of their undesirable effects is the lack of representative samples, matching those resulting from the environmental degradation of plastic wastes. To such end,...
Article
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The aim of this study was the establishment of a UHPLC-QqQ-MS/MS method to determine methotrexate in postmortem biological samples and quantify the postmortem distribution of methotrexate in a case of fatal intoxication of this drug. A volume of 100 µL or 100 mg of postmortem specimens was precipitated with 400 µL of cold methanol and then analyzed...
Article
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The Alamar Blue (AB) assay is widely used to investigate cytotoxicity, cell proliferation and cellular metabolic activity within different fields of toxicology. The use of the assay with nanomaterials (NMs) entails specific aspects including the potential interference of NMs with the test. The procedure of the AB assay applied for testing NMs is de...
Article
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Concentrations of total mercury, total selenium, and cadmium ([THg], [TSe], [Cd]) were determined in hair of California sea lion (Zalophus californianus) pups from four islands of the Gulf of California and the Baja California Pacific coast (NG, CG, NP, and CP) to identify geographical differences and the effect of Se against Hg toxicity (TSe:THg m...
Cover Page
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[Frontiers in Plant Science] Call for participation in our article collection, “Environmental Pollutants in Agroecosystem: Toxicity, Mechanism, and Remediation” Manuscript submission is now open for a new article collection I am editing on “Environmental Pollutants in Agroecosystem: Toxicity, Mechanism, and Remediation”. We would like to consider...
Poster
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The manuscript titled "m R.N.A. PURIFICATIONS PROCESS : affinity chromatography , magnetic beads and graphene coated. Large scale Production and toxicological aspects" is very well written and has been accepted. Your article will get published soon as possible.
Article
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Exhumation means legal digging a dead body out of a grave buried in a legitimate fashion done by the court order under section 176 CrPC, not applicable to retrieval of dead bodies buried by criminals illegally. Exhumation is done for a number of reasons including determination of cause of death and establishment of identity in unnatural deaths. The...
Article
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Most disposable plastic products are degraded slowly in the natural environment and continually turned to microplastics (MPs) and nanoplastics (NPs), posing additional environmental hazards. The toxicological assessment of MPs for marine organisms and mammals has been reported. Thus, there is an urgent need to be aware of the harm of MPs to the hum...
Preprint
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We provide a systematic treatment of $D$-optimal design for binary regression and quantal response models in toxicology studies. For the two-parameter case, we provide an analytical equation (WC equation) for computing the $D$-optimal design quickly and when analytical solution is not available, we apply particle swarm optimization to solve for the...
Article
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Loss of the sense of smell (anosmia) has been included as a COVID-19 symptom by the World Health Organization. The majority of patients recover the sense of smell within a few weeks postinfection (short-term anosmia), while others report persistent anosmia. Several studies have investigated the mechanisms leading to anosmia in COVID-19; however, th...
Poster
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Mariinskaya Gallery named after Maria Shapovalenko" fb.me/MariinskayaGallery, https://www.facebook.com/groups/435405866923911/media/albums, NGO "Information for all"), Russia, 121096, Moscow, POB 44. www.ifap.ru, , +7 (918) 443-00-43, +7 (988) 955-61-32, +7 (928) 434-20-84. papa888@list.ru, latyshev-1970@inbox.ru, olegl@ioso.ru, ima. Abstract Aim o...
Article
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Building institutional and procedural bridges between science and policy is a vital role for law. Fundamental to the success of this work is the development of more sophisticated, nuanced understandings of scientific knowledge production than those which are current in legal and policy spheres. In this paper, I consider scientific controversies tha...
Article
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Edible flowers were used as food thousands of years ago by the Greeks, Romans and Chinese, and their application was mainly in cooking and for extracts, syrups and more. Initially, they were consumed for medical purposes, but then it was found that some are spicy, others resemble various herbs, have a specific color, aroma and good taste. In modern...
Book
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This book provides essential information on the role of phytonanotechnology in the removal of environmental pollutants and covers recent advances in experimental and theoretical studies on plant-derived nanoparticles. It also discusses their current and potential applications and challenges.The combination of nanotechnology and phytoremediation, wh...
Article
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The concept of green marketing mix is as well as the conventional marketing mix refers to the satisfaction of customer needs, wants, and desires related to the maintenance and preservation of the environment. Consumers interest in environmental care creates opportunities for companies to apply green marketing and to increase sales. Green marketing...
Article
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The inhalation toxicity of carbon nanofibers (CNFs) is not clearly known due to relatively few related studies reported. An acute inhalation study and short-term inhalation study (5 days) were therefore conducted using Sprague-Dawley rats. In the acute inhalation study, the rats were grouped and exposed to a fresh air control or to low (0.238 ± 0.1...
Article
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Amphibians, which can live in aquatic and terrestrial environments, are a good indicator of pollution in these areas. Although frog leg is not consumed frequently in some cuisines including Turkey, it is important in terms of evaluating metal accumulation since it is preferred as human food in many European countries. In this study, the quantities...
Article
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We present a case study that provides a practical step-by-step example of how the internal Threshold of Toxicological Concern (iTTC) can be used as a tool to refine a TTC-based assessment for dermal exposures to consumer products. The case study uses a theoretical scenario where there are no systemic toxicity data for the case study chemicals (avob...
Article
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This study presents spatial distribution, sources and toxicological risks of As, Cr, Cu, Hg, Ni, Pb, and Zn in the surface sediments from north-western Karnataka, southern India. Heavy metals (except Hg) are 1–5 times enriched than upper continental crust. High concentration of Cr, Ni, Cu, and Zn is in the central Kudalgaon, Devarayi, and Tavargatt...
Article
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We are imminently faced with the challenges of an increasingly aging population and longer lifespans due to improved health care. Concomitantly, we are faced with ubiquitous environmental pollution linked with various health effects and age-related diseases which contribute to increased morbidity with age. Geriatric populations are rarely considere...
Article
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Abstract Background A key aspect of any new material safety assessment is the evaluation of their in vivo genotoxicity. Graphene oxide (GO) has been studied for many promising applications, but there are remaining concerns about its safety profile, especially after inhalation. Herein we tested whether GO lateral dimension, comparing micrometric (LG...
Presentation
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The results of this study indicate that titanium dioxide nanoparticles (nano-TiO2) possess adsorptive, photocatalytic, bactericidal, virucidal and fungicidal properties, which are used in antibacterial coating, for air and water disinfection. In parallel with studies of the physicochemical characteristics of titanium dioxide, its toxicological asse...
Article
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Mariinskaya Gallery named after Maria Shapovalenko" fb.me/MariinskayaGallery, https://www.facebook.com/groups/435405866923911/media/albums, NGO "Information for all"), Russia, 121096, Moscow, POB 44. www.ifap.ru, , +7 (918) 443-00-43, +7 (988) 955-61-32, +7 (928) 434-20-84. papa888@list.ru, latyshev-1970@inbox.ru, olegl@ioso.ru, ima.
Preprint
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Acceptance Letter to Speak at the PHARMAMEET2023 Dear Dr. Mauro Luisetto, On behalf of our the Scientific organizing committee we would like to inform you that your abstract entitled "m R.N.A. Purifications Process: Affinity chromatography, magnetic beads and graphene coated. Large scale Production and Toxicological
Preprint
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Birth defects are functional and structural abnormalities that impact 1 in 33 births in the United States. Birth defects have been attributed to genetic as well as other factors, but for most birth defects there are no known causes. Small molecule drugs, cosmetics, foods, and environmental pollutants may cause birth defects when the mother is expos...
Article
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Biopharmaceuticals production is based on a GMP system of quality control used for the regulatory scope. Relvant for this role the analytical procedure, specificity and sensibility of the methods to test raw materials but also the final products before commercialization. Aim of this work is to verify the role played by nanolipids on Raman Spettrosc...
Article
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Engineered nanomaterials pose occupational health and environmental concerns as they possess unique physical and chemical properties that can contribute to toxicity. High throughput toxicity screening methods are needed to address the increasing number of nanomaterials in production. Here we used a zebrafish photomotor response (PMR) test to evalua...
Article
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Wild and managed pollinators are essential to food production and the function of natural ecosystems; however, their populations are threatened by multiple stressors including pesticide use. Because pollinator species can travel hundreds to thousands of meters to forage, recent research has stressed the importance of evaluating pollinator decline a...
Article
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The Special Issue of Nanomaterials “Frontiers in Nanotoxicology” highlights the modern problems of nanotoxicology and nanobiomedicine, including the toxicity of metal-based, silicon-based, carbon-based, and other types of nanoparticles, occupational safety of nanoproduction workers, comprehensive assessment on new biomedical nanomaterials, improvem...
Article
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The Medical Device (MD) Regulation EU 2017/745 (MDR) has provided a completely new and more robust regulatory framework at guarantee of the safety and efficacy of therapeutic options accessing the market. At the same time, the MDR poses several challenges for stakeholders, among which, the most significant lying on MDs made of substances (MDMS) who...
Article
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The exposure of animals to toxicants may cause a depletion in the energy uptake, which compromises reproduction and growth. Although both parameters are ecologically relevant, they usually need long-term bioassays. This is a handicap for the availability of toxicological data for environmental risk assessment. Short-term bioassays conducted with en...
Article
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Background Now that it is possible to efficiently classify and save tissue images of laboratory animals using whole-slide imaging, many diagnostic models are being developed through transfer learning with Convolutional Neural Network (CNN). In this study, transfer learning was performed to gain toxicopathological knowledge using CNN models such as...
Preprint
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trans-Fatty acids (TFAs) are unsaturated fatty acids containing at least one carbon-carbon double bond in trans configuration, which are classified into two groups according to their food source: industrial TFAs (iTFAs) and ruminant TFAs (rTFAs). Previous epidemiological evidence has demonstrated a preferential association of iTFAs, rather than rTF...
Article
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Purpose of Review Emergency providers are well prepared for the rapid diagnosis and management of common etiologies of altered mental status. However, patients with persistently altered mental status of unclear etiology can present diagnostic and management challenges. Recent Findings Enhanced laboratory and imaging testing for patients in the eme...
Article
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Bisphenol A (BPA), a synthetic chemical which has raised concerns due to its potential toxicological effects on humans, has been widely detected in canned and non-canned meat and meat products. This study estimated BPA migration from packaging to non-canned and canned meat products by developing two probabilistic models. BPA concentration data in p...
Article
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Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs. Although many publications on nephrotoxicity have been conducted globally, there needs to be a scientometric study to systematically analyze the intellectual landscape and frontie...
Article
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Introduction : The study aim was to explore a toxicological property and antitumor action of the novel pyridine derivative LHT-17-19 in cell culture and on experimental models of lung cancer in mice. Materials and methods : The study was performed on male and female ICR(CD-1), male BALB/c, male BALB/c nu/nu mice. Pyridine derivative (LHT-17-19) was...
Article
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Copper (Cu) is an essential microelement for animals. However, sheep are particularly susceptible to Cu intoxication, a deadly disease reported worldwide. The risk of developing this poisoning is higher in vulnerable breeds and in intensively managed lambs or milk sheep. Two types of Cu intoxication can occur depending on the chronic or acute expos...
Article
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A risk-based approach in food safety monitoring suggests that the number analysis of contaminants and (or) products depends on the risk caused by product contamination, first of all for consumer health and economic (prevention of unsafe products realization). Risk-oriented sampling, planning and assignment of studies can be opposed with representat...
Preprint
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The widespread ethnomedical practice of dromedary urinotherapy as a remedy against various illnesses is well recognized in traditional dromedary countries, and multiple researchers tried to unravel its bioactive potential and provide scientific evidence through in vivo and in vitro experiments. None of these studies (i) measured urine osmolarity pr...
Poster
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Being characterized by considerable percentage of fat, eggs represent a food type capable of accumulating high amount of lipophilic pesticides. These contaminants cannot be destroyed by cooking or other processing. Thus, food control is crucial to avoid high intake of pesticides, with significant toxicological effects on humans. In this study, an a...
Preprint
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Aim of this work is to investigate the role played by graphene and its derivates in some relevant manifacturing process like purification and absorbtion. The chemical phisical properties of this innovative product make possible to understand why they are Used in many bio-medical and other fields like biosensors, in water purifing, to remove heavy m...