Solubility - Science topic

A system of two partial differential equations with fractional diffusion is considered in this study. The system extends the conventional Zakharov system with unknowns being nonlinearly coupled complex- and real-valued functions. The diffusion is understood in the Riesz sense, and suitable initial–boundary conditions are imposed on an open and boun...

The thermodynamic description of the alkali-silica reaction is incomplete, due to the lack of thermodynamic data for the alkali-silica reaction products. Here, we estimate the temperature-dependent thermodynamic properties of Na-or K-shlykovite phases which are found to form during alkali-silica reaction in concrete. The thermody-namic properties a...

Octacalcium phosphate (OCP) has a layered structure and various carboxylate ions can be incorporated into its structure as interlayer ions. In recent studies, aromatic carboxylate ions have been incorporated into OCP to impart fluorescence properties. In such fluorescent OCP materials, the incorporated carboxylate ions can be regarded as ‘crystal d...

El presente artículo investigativo se encarga del estudio del diseño de las lagunas facultativas, donde se tiene en cuenta la combinación de la teoría y la experiencia práctica obtenida de estudios ya realizados; se hace un enfoque sobre los aspectos del agua residual, el por qué esta es un problema, cómo se trata este problema, qué son las lagunas...

Micro-and nanoplastics are emerging pollutants with a concerning persistence in the environment. Research into their environmental impact requires addressing challenges related to sensitively and selectively detecting them in complex ecological media. One solution with great potential for alleviating these issues is using radiolabeling strategies....

This study explores the edaravone solubility space encompassing both neat and binary dissolution media. Efforts were made to reveal the inherent concentration limits of common pure and mixed solvents. For this purpose, the published solubility data of the title drug were scrupulously inspected and cured, which made the dataset consistent and cohere...

The oxidative potential (OP) is defined as the ability of inhaled PM components to catalytically/non-catalytically generate reactive oxygen species (ROS) and deplete lung antioxidants. Although several studies have measured the OP of particulate matter (PM OP) soluble components using different antioxidants under neutral pH conditions, few studies...

The consumption of non-steroidal anti-inflammatory drugs (NSAIDs) have increased lately around the world, as they are considered essential and popular drugs for effective reduction of pain and inflammation. They have analgesic, antipyretic, and anti-inflammatory activities; also, it was reported recently that they protect against various critical d...

In our study we investigated the acute toxicity of а newly synthesized creatine lysinate as well as its effect on the biochemical parameters in mice. Creatine lysinate exerts better solubility in water (3.3%) in comparison to creatine monohydrate (1.4%) at 20 °C and it is determined as a non-toxic after intraperitoneal (LD50 – 4543 mg/kg) and oral...

The direct epoxidation of mixed ethene and propene feedstocks using hydrogen peroxide over a titanium silicalite (TS-1) catalyst was investigated within a continuous trickle bed reactor operating in laboratory scale. Methanol was employed as the reaction solvent. This study aimed to streamline the epoxidation process by obviating the need for prior...

Advances in electrochemical devices have been primarily driven by the discovery and development of electrolyte materials. However, finding an electrolyte that exhibits both high ionic conductivity and chemical and electrochemical stability remains a significant challenge. Here, we developed such an electrolyte with heavily Sc-doped BaSn 0.3 Sc 0.7...

Eggplant (Solanum melongena L.) cultivar "Nour" was evaluated under salt stress conditions using in vitro and hydroponic cultures. Plants were grown on media supplemented with (0.0 mM, 50 mM, 100 mM, 150 mM )sodium chloride (NaCl). Shoot length, root length, shoot weight, root weight, root number, and leaf area were decreased with elevated salinity...

Cannabidiol (CBD), derived from the cannabis plant, has gained significant attention due to its potential therapeutic benefits. However, one of the challenges associated with CBD administration is its low bioavailability, which refers to the fraction of an administered dose that reaches systemic circulation. This limitation necessitates the explora...

Usually, Hansen's theory and the COSMO continuous solvation models have been used for the selection of solvents related to a solute, using the HSPiP and COSMO-RS computational tools, respectively. Those tools are not always available to many researchers; for this reason, Microsoft Excel has been used for the estimation of good solvents in the extra...

Inflammasomes, primarily responsible for the activation of IL-1β, have emerged as critical regulators of the tumor microenvironment. By using in vivo and in vitro brain metastasis models, as well as human samples to study the role of the NLRP3 inflammasome in triple-negative breast cancer (TNBC) brain metastases, we found NLRP3 inflammasome compone...

Loess owns the characteristics of collapsibility, disintegration and solubility, which pose a challenge to engineering construction. To examine the shear strength of basalt fiber-reinforced (BFR) loess, consolidated undrained (CU) triaxial tests were conducted to explore the impacts of water content (w), fiber length (FL), fiber content (FC) and ce...

The 4-substituted 3-amino-1,2,5-oxadiazole 1 from the Malaria Box Project of the Medicines for Malaria Venture foundation shows very promising selectivity and in vitro activity against Plasmodium falciparum. Within the first series of new compounds, various 3-acylamino analogs were prepared. This paper now focuses on the investigation of the import...

Fenofibrate is a lipid lowering drug used in the treatment of hyperlipidemia, which is not soluble in water and lower absorption in gastric fluid. In order to improve the solubility and oral absorption of the drug in gastric fluid and to enhance its dissolution rate solid dispersions evaluated. Solid dispersions of Fenofibrate were prepared using P...

The models presented are developed on the basis of Pitzer ion interactions approach [1-6]. The previously developed by Christov, and by Christov and co-authors Pitzer approach based not concentration restricted thermodynamic models for rubidium binary systems (RbCl-H2O, RbBr-H2O, RbI-H2О, Rb2SO4-H2O and Rb2SeO4-H2O) are used to parameterize models...

Two aspects of the biosynthesis of the non-canonical terpene synthase for 2-methylisoborneol have been studied. Several 2-methylisoborneol synthases have a proline-rich N-terminal domain of unknown function. The results presented here demonstrate that this domain leads to a reduced enzyme activity, in addition to its ability to increase long-term s...

Introduction: Solubility studies and obtaining physicochemical data on drugs in pure solvents belonging to different chemical classes are key to developing new drug formulations. In this work, Hansen partial solubility parameters (HSP) were calculated to assess the miscibility and intermolecular interactions of barnidipine in seventeen pure solvent...

In this study we developed new thermodynamic models for solution behavior and solid-liquid equilibrium in eight (8) acetate (Li(CH3COO)-H2O, Na(CH3COO)-H2O, K(CH3COO)-H2O, Rb(CH3COO)-H2O, Cs(CH3COO)-H2O, Mg(CH3COO)2-H2O, Ba(CH3COO)2-H2O, Tl(CH3COO)-H2O)) binary systems from low to very high concentration at 25 o C. Models are developed on the basis...

A bstract 2 d QCD, Yang-Mills theory with gauge group G and massless quarks in representations ( R ℓ , R r ) of G , flows in the infrared to a CFT or a TQFT depending on whether spectrum is gapless or gapped. We identify the infrared effective theory and construct the explicit RG flow map between the QCD operators in the UV and the IR, in particula...

The purpose was to determine the solubility data of guanidinium 5,5’-azotetrazolate (GAzT) in various pure solvents including methanol, ethanol, acetone, acetonitrile, ethyl acetate, 1,4-dioxane, N,N-dimethylformamide (DMF), and Dimethyl sulfoxide (DMSO) at temperatures T = 25oC, 50oC and pressure P = 1 atm. Solubility data of guanidinium 5,5’- azo...

Abstract. Dissolution and leaching of salts from the soil primarily promotes the loss of porosity and connectivity of crystallization. There is thus an increase in permeability and the weakening of the soil. Saline soils in these conditions are more deformation – suffusion sedimentation. Therefore, the issues of forecasting suffusion deformations b...

The models described in this study are of high importance in development of thermodynamic database needed for nuclear waste geochemical storage, as well as for technology for extracting cesium resources from saline waters. The models are developed on the basis of Pitzer ion interactions approach [1-5]. The previously developed by Christov, and by C...

Candidate cis-regulatory elements (cCREs) in microglia demonstrate the most substantial enrichment for Alzheimer’s disease (AD) heritability compared to other brain cell types. However, whether and how these genome-wide association studies (GWAS) variants contribute to AD remain elusive. Here we prioritize 308 previously unreported AD risk variants...

May and Filella (J Solution Chem 52:754–761, 2023) concluded that they had verified the data in Gamsjäger et al. (Chemical thermodynamics of tin OECD, Nuclear Energy Agency Data Bank, Leoben, 2012). However, they used exactly the same primary data and not surprisingly came up with essentially the same values. They (1) provided no new data; (2) did...

Banana (Grand Nain) is widely grown in India and it plays a crucial role in both agricultural and industrial economy of country. A field experiment was carried out using banana as a test crop during 2012-2013 (plant) and 2013-2014 (ratoon) at Soil and Water Management Research Unit, NAU, Navsari. Present experiment was conducted at fixed site, for...

Rechargeable aqueous Zn‐I 2 battery (ZIB) has been regarded as a promising energy storage candidate. However, the soluble polyiodides shuttling and rampant Zn dendrites growth hamper its commercial implementation. Herein, a hetero‐polyionic hydrogel is designed as the electrolyte for ZIBs. On the cathode side, iodophilic polycationic hydrogel (PCH)...

Regular lard (RL) was chemically modified into isopropyl‐branched lard (BL). The isopropyl group was introduced into the triglyceride structure via a reaction of carbon–carbon double with isopropyl bromide in presence of ethylaluminum sesquichloride. The reaction was confirmed with gas chromatography–mass spectroscopy, nuclear magnetic resonance, i...

Poly(N,N-dimethylaminoethyl methacrylate) is a polyelectrolyte with many important chemical and physical properties and, above all, offers a wide range of interesting biological properties. Currently, research on this polymer is ongoing in several centres around the world. The process of polymerizing the monomer is not easy, as there are difficulti...

Plant-based proteins are rapidly emerging, while novel technologies are explored to offer more efficient extraction processes. The current study aimed to evaluate the effects of pulsed electric fields (PEFs) and temperature on the extraction of soluble proteins from nettle leaves (Urtica dioica L.) and identify an optimal operational range for the...

Graph neural networks have recently become a standard method for analyzing chemical compounds. In the field of molecular property prediction, the emphasis is now on designing new model architectures, and the importance of atom featurization is oftentimes belittled. When contrasting two graph neural networks, the use of different representations pos...

We introduce HAPPY (Hierarchically Abstracted rePeat unit of PolYmers), a new string representation for polymers, designed to efficiently encapsulate essential polymer structure features for property prediction. HAPPY assigns single constituent elements for groups of sub-structures and employs grammatically complete and independent connectors betwe...

Hepatitis B virus (HBV) infection remains a global health concern, with persistent covalently closed circular DNA (cccDNA) hindering curative treatments. Coumarin is one of these natural compounds that could be utilized as a pharmaceutical agent due to its stability, solubility, availability and low toxicity. Previous studies demonstrate their effi...

Carbitol acetate (CA) could be a remarkable for CO2 absorption due to its high boiling point, low viscosity, and high CO2 solubility. Using a laboratory-scale Raschig ring packed-column, mass transfer studies of CO2 in carbitol acetate have been performed at ambient temperature and pressure. Liquid and gas side physical individual mass transfer coe...

The light conditions are of utmost importance in any microalgae production process especially involving artificial illumination. This also applies to a chrysolaminarin (soluble 1,3‐β‐glucan) production process using the diatom Phaeodactylum tricornutum. Here we examine the influence of the amount of light per gram biomass (specific light availabili...

We report here the first in-depth theoretical and experimental investigations of Mn substitution within the CoSb 3-skutterudite. A systematic and comprehensive approach was employed to first determine the feasibility of single/cosubstitution for Mn with Te and then assess its effect. Subsequently, experimental realization of the samples was conduct...

El estudio tuvo como objetivo evaluar la contaminación del aire por partículas sedimentables en domicilios en la zona urbana de la Provincia de Leoncio Prado, Departamento de Huánuco. El tipo de estudio fue transversal y de nivel descriptivo, la muestra estuvo conformada por 12 zonas de monitoreo. Para el diseño del soporte de placas receptoras, la...

El objetivo de la investigación fue evaluar el efecto del aceite esencial de molle en los frutos de durazno. Los frutos de durazno fueron sometidos a operaciones previas de selección, clasificación, lavado, desinfección, drenado, aplicación del aceite esencial, conservación de los frutos a medio ambiente y evaluación de la pulpa en sus característi...

Lithium‐sulfur batteries are among the promising high‐capacity candidates owing to the superior theoretical capacity of sulfur, when compared with conventional cathodes such as LiCoO 2 . However, several issues must be addressed before these batteries can be considered fully operational. Major issues regard the insulating nature of sulfur and the s...

Nowadays various drugs synthesized by various computational drug designs as well as various drugs have complex structure. Due to their complex structure, higher molecular weight which will increases solubility issues. Solubility is the most important and challenging task for researchers. Bioavailability and absorption of a drug depends on solubilit...

Visualizing polymer chain growth is always a hot topic for tailoring structure‐function properties in polymer chemistry. However, current characterization methods are limited in their ability to differentiate the degree of polymerization in real‐time without isolating the samples from the reaction vessel, let alone to detect insoluble polymers. Her...

A series of new difluoroboronate anchored acylhydrazone (BOAHY) derivates were prepared in good yields via a simple two-step reaction starting from commercially available reagents. The spectroscopic properties of these dyes can be easily tuned through appropriate functionalization and post-functionalization. While these BOAHYs are dim in solution,...

In this study, a solvent based chemical upgrading process for coal was applied for chemical upgrading of biomass. Biomass was solvent treated at 320, 350, 380, 400, and 420°C, for 2 h with 1-methylnapthlene (1-MN) solvent. Upgraded biomass samples were obtained by removing 1-MN from the solvent treated samples using hexane washing approach. A part...

El níspero del Japón Eriobotrya japonica (Thunb) Lindl. es un frutal subutilizado, que ha sido poco estudiado en Cuba. Es un cultivo de fácil manejo y con grandes potencialidades para la industria. El objetivo de este estudio fue evaluar la diversidad de la especie en 24 accesiones y resaltar las potencialidades de estos. Siguiendo las directrices...

Twenty-three chilli genotypes were evaluated during rabi season of year 2022-23 in a Randomized Block Design for yield traits and tolerance to thrips. The chilli accessions differed significantly for all the traits evaluated. The lowest thrips population recorded in the genotypes Seln-BBL and Seln-14 throughout the cropping period, whereas Percent...

In this paper, a rapid and efficient method for the preparation of scopolamine hydrobromide with high purity was established, named as magnetic field-induced crystallization. Based on the difference in solubility between scopolamine and scopolamine hydrobromide, salifying crystallization was selected and then treated with the synergistic effect of...

Regenerative endodontic procedures (REPs) aim at recreating dental pulp tissue using biomaterials such as hydrogels. Their bioactivity is mostly related to the nature of biomolecules or chemical compounds that compose the endodontic hydrogel. However, many other parameters, such as hydrogel concentration, bioactive molecules solubility, and apex si...

This study aims to determine the predictive value of the soluble suppression of tumorigenicity 2 (sST2) biomarker in atrial fibrillation (AF) recurrence. This prospective, observational study included patients with AF referred for electrical cardioversion (ECV) or pulmonary vein isolation (PVI) procedures. Baseline characteristics were collected, a...

Henry's law constant, which describes the proportionality of dissolved gas to partial pressure of free gas in liquid--gas equilibrium systems, can also be applied to mass transport applications. In this work, we investigated an approach for determining the solubility of noble gases in a molten salt liquid utilizing the equilibrium concept of Henry'...

Copyright@ : Nurhan Kishali | Biomed J Sci & Tech Res | BJSTR. MS.ID.007775. 40463 ARTICLE INFO ABSTRACT A new and convenient synthesis for pyrrolidine derivatives has been developed starting from 3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione. 3a,4,7,7a-tetrahydroisobenzo furan-1,3-dione was reacted with amines to give N-ethyl and N-phenyl isoindole...

Applying a formulation on the skin represents a patient-acceptable and therapeutically effective way to administer drugs locally and systemically. However, the stratum corneum stands as an impermeable barrier that only allows a very limited number of drugs to be distributed in the underlying tissues, limiting the feasibility of this administration...

Acetaminophen solubility in the glycerol and ethanol mixture was determined by a simple shake-flask technique at different temperatures and fitted to some mathematical models and the models’ accuracy was investigated by the computation of the mean relative deviations. The densities of acetaminophen saturated mixtures were also studied by the Jouyba...

Two new species of sect. Trachyspermi isolated from soil are proposed, namely, T. albidus (ex-type AS3.26143T) and T. rubidus (ex-type AS3.26142T), based on the integrated taxonomic methods. Morphologically, T. albidus is characterized by slow growth, white gymnothecia, singly-borne asci and ellipsoidal echinulate ascospores. Talaromyces rubidus is...

This preliminary study introduces the incorporation and chemical stabilization of sulfur waste into a geopolymer matrix and explores the concept of material production for further environmental and engineering solutions. In this study, a novel synthesis procedure for sulfur-based geopolymers was introduced, and the role of sulfur in geopolymers and...

At present, the V-Ti-Co phase diagram is not established, which seriously hinders the subsequent development of this potential hydrogen permeation alloy system. To this end, this article constructed the first phase diagram of the V-Ti-Co system by using the CALculation of PHAse Diagrams (CALPHAD) approach as well as relevant validation experiments....

Accurate and appropriate prostate cancer detection can significantly reduce the death rate. In this research, the Henry Firefly Gas Solubility Optimization (HFGSO)-based Deep Residual Network (DRN) is established for the autonomous detection of prostate cancer. The pre-processing is done by Cuckoo Search-Based (T2FCS) filter and Type 2 Fuzzy. Subse...

By utilizing hydrogen as an eco-friendly energy source, many metals are exposed to gaseous (pressurized) hydrogen. High-strength steels with an ultimate tensile strength of 800 MPa and above are especially susceptible to hydrogen-induced fracturing, also referred to as hydrogen embrittlement (HE). Both the microstructure and phase fractions within...

Mitochondrial hypochlorite (ClO−) plays important and often contradictory roles in maintaining the redox balance of mitochondria. Abnormal ClO− levels can induce mitochondrial inactivation and further cause cell apoptosis. Herein, we have developed an anthracene carboxyimide-based fluorescent probe mito-ACS for imaging mitochondrial ClO− in living...

Nitrate is a stable and highly soluble ion with a low potential for precipitation or adsorption, nitrate is seldom present in geological formations and therefore contamination due to nitrate is mainly attributed to anthropogenic sources. Pollution of water resources by nitrate occurs due to many reasons which has effects on environment and human he...

Both machine learning and physiologically-based pharmacokinetic models are becoming essential components of the drug development process. Integrating the predictive capabilities of physiologically-based pharmacokinetic (PBPK) models within machine learning (ML) pipelines could offer significant benefits in improving the accuracy and scope of drug s...

Metastable polymorphs, although having better solubility and dissolution rates, can transform to the stable form. Therefore, there is a need to improve the stability of metastable forms. One way to achieve this is to inhibit the transformation rate by using additives in the crystallization process or in the drug dosage form. Additives usually impro...