Skin Diseases - Science topic

Skin health is essential for everyone. In addition to supporting someone who can reduce self-confidence, skin diseases can also interfere with a person's concentration in activities. An expert system is a system designed to be able to imitate the expertise of an expert in answering questions and solving a problem. The expert system will solve a pro...

Accurate differentiation between infectious and non‐infectious skin diseases is crucial in the field of dermatological diagnosis, and although deep learning techniques have achieved remarkable results in the classification of a wide range of dermatological diseases, there is still a lack of effective unified frameworks to achieve this goal. To this...

Nanotechnology involves creating functional frameworks at the nanoscale, making it appealing to fields ranging from materials science to biology. Recent rapid advances in nanotechnology have made it possible to combine numerous beneficial, detecting, and focusing experts into nanoparticles for the identification, prevention, and treatment of malign...

A piodermite gangrenosa é uma doença inflamatória rara, caracterizada por úlceras cutâneas necróticas dolorosas e de rápida progressão. Sua etiologia ainda não é completamente compreendida, mas acredita-se estar associada a uma disfunção do sistema imunológico, frequentemente ocorrendo em pacientes com doenças inflamatórias intestinais, artrite reu...

In many cases, chronic inflammatory dermatoses are accompanied by changes of the nails or periungual region. Sometimes nail changes occur even before the onset of the particular skin disease. In some cases, specific lesions of the nails and the perionychium can contribute to the diagnosis. This review describes the most common nail and periungual c...

Objective The potential contribution of psychosocial work exposures to skin problems is largely overlooked in the occupational health literature. To address this knowledge gap, we examined cross-sectional and prospective associations between six psychosocial work exposures (i.e., quantitative demands, job control, social support, emotional demands,...

Background/Objectives: Ceramide, a sphingolipid metabolite, has emerged as a key player in various physiological and pathological processes. Changes in ceramide levels are associated with the occurrence and development of various diseases, highlighting its potential as a biomarker of various clinical diseases. Methods: The biosynthesis and metaboli...

Citation: Igarashi, A.; Yoshida, T.; Sunaga, Y.; Nawata, H.; Arima, K. Abstract: Background/Objectives: Prurigo nodularis (PN) is associated with considerable disease burden. Limited information exists about the epidemiology, treatment patterns, and impact of PN. This retrospective study used Japanese health insurance claims data to investigate the...

Skin diseases are listed among the most frequently encountered diseases. Skin diseases such as eczema, melanoma, and others necessitate early diagnosis to avoid further complications. This study aims to enhance the diagnosis of skin disease by utilizing advanced image processing techniques and an attention-based vision approach to support dermatolo...

Background Cutaneous leishmaniasis (CL) is a neglected skin disease that affects millions of people worldwide. Its visible symptoms and impact on physical appearance can lead to social rejection, stigma, and discrimination for patients with cutaneous leishmaniasis. It is a public health and social problem in East Africa. However, there was no concl...

In an Internet of Medical Things (IoMT) framework, this study suggests an integrated system that uses Support Vector Machines (SVM) and Smooth Grad to improve the interpretability and accuracy of skin disease classification. Real-time data gathering combined with interpretability-enhanced machine learning guarantees faster and more accurate diagnos...

Stevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN) is a spectrum of mucocutaneous hypersensitivity reactions. This report details the case of an18-year-old male patient with a history of HIV who developed extensive skin lesions and mucosal involvement after using carbamazepine. The diagnosis was confirmed clinically, and it was treated...

Background Pruritus is a common skin symptom manifesting with an unpleasant sensation and desire to itch and scratch. Pruritis can be a hallmark of many skin diseases as well as other non cuatneous diseases. Aim of the study To compare the efficacy of gabapentin versus narrow band UVB versus combination of both in treatment of uremic pruritus. Me...

Dermatology diseases index fourth edition is first largest and most updated index of skin diseases in the world containing more than 5000 names ,and this index not just index so read to discover https://www.mediafire.com/folder/4sir5u7xu9rs2/Index

The disruption of the skin barrier and immune function has been linked to several skin conditions, including atopic dermatitis (AD), psoriasis, and acne. Both resident and non-resident immune cells, along with the skin’s barrier system, play crucial roles in innate immunity. Recent research on skin microbiota has enhanced our understanding of the i...

Skin lesion segmentation is crucial for identifying and diagnosing skin diseases. Accurate segmentation aids in identifying and localizing diseases, monitoring morphological changes, and extracting features for further diagnosis, especially in the early detection of skin cancer. This task is challenging due to the irregularity of skin lesions in de...

Purpose of Review In this narrative review, we provide an overview of how adherence to a Mediterranean dietary pattern can complement traditional treatment strategies for psoriasis, acne, and hidradenitis suppurativa. We emphasize the importance of an integrated approach, with dietary interventions as a key component of holistic patient care. Rece...

Objective Acne is one of the most common skin diseases, especially among teenagers. Many factors were blamed for creating acne including nutrition. The purpose of this study was to evaluate the relationship between body mass index, oxygen radical absorption capacity (ORAC), and healthy eating index (HEI), and acne among adolescents. This case-contr...

Background Skin diseases are a category of chronic conditions that often impact patients’ appearance, potentially leading to psychological issues, including sexual dysfunction. The present study is an attempt to determine the global prevalence of female sexual dysfunction (FSD) in women with skin diseases. Methods For this systematic review and me...

Hidradenitis suppurativa is a chronic skin disease associated with significant disease burden. To assess patients’ treatment benefits, disease-specific outcomes measurement is needed. This study aimed to develop a questionnaire called Patient Benefit Index for hidradenitis suppurativa (PBI-HS). After an open-item survey, the items were condensed in...

Dyschromatosis, a group of pigmentary dermatoses, accompany both hyper- and hypo-pigmentation, including dyschromatosis symmetrica hereditaria (DSH), dyschromatosis universalis hereditaria (DUH), and familial progressive hyper- and hypo-pigmentation (FPHH). A peculiar phenotype of dyschromatosis presented as multiple lentigines and hypopigmentation...

Psoriasis is a chronic inflammatory skin disease affecting over 60 million people worldwide, often linked to comorbidities such as psoriatic arthritis and cardiovascular disease. Beyond physical symptoms, psoriasis can significantly impact major life-changing decisions (MLCDs), leading to long-term consequences and missed opportunities. This study...

Psoriasis is a chronic inflammatory skin disease influenced by both genetic and environmental factors. Despite extensive research, its precise etiology remains unclear, posing significant challenges to understanding and treatment. The disease pathogenesis involves self-reactive T cells and immune-related cytokines. Genome-wide association studies h...

Introduction:Psoriasis is a chronic skin disease that affects both the physical and social aspects of a patient’s life. The disease's severity, as measured by the Psoriasis Area Severity Index (PASI), can significantly impact the patient’s quality of life, which can be calculated using the Dermatology Life Quality Index (DLQI). Objectives: To asses...

This research paper delves into the exploration of various computational models utilized in creating skin disease classifiers, aiming to enhance diagnostic accuracy and optimize potential accessibility to isolated patients. By investigating the different types of computational models employed in this context, this paper aims to shed light on how th...

It is about predicting and classifying the type of skin disease accurately for an improved treatment process.

Introduction: Overweight and obesity are significant global public health concerns, with prevalence rising alarmingly in recent decades. Despite this, few studies have investigated the association between overweight/obesity and skin conditions. Objectives: This study aimed to assess the frequency of dermatological manifestations among overweight an...

Introduction: Obesity can have many effects on skin physiology. It is involved in dermatologic diseases like acanthosis nigricans, acrochordons, keratosis pilaris, hirsutism, and striae distensae. Objectives: To determine the proportion of various cutaneous manifestations in obese patients. Materials and Methods: This cross-sectional study was cond...

Atopic dermatitis (AD) is a chronic inflammatory skin disease often requiring systemic therapies for moderate-to-severe cases. Janus kinase (JAK) inhibitors, including upadacitinib, have emerged as effective options, targeting pro-inflammatory cytokines involved in AD pathogenesis. However, adverse dermatologic reactions, such as rosacea-like erupt...

Increasing evidence supports the idea that social determinants of health, e.g., educational attainment, employment, and community context, directly affect health status. Researchers are also beginning to explore the impact of social factors on skin diseases, though no formalized research field, to the authors’ knowledge, provides a structured frame...

Background China's healthcare resources are limited and unevenly distributed, with a notable urban-rural gap. Enterprise-led internet healthcare platforms have become an important solution for optimizing resource allocation, improving accessibility, and enhancing efficiency in mainland China. However, detailed analysis of their online consultation...

Background Stem cell therapy shows promise for treating skin diseases and enhancing medical aesthetics. However, safety data for subcutaneous injection of stem cells remain limited. In this study, we evaluated the toxicity of human umbilical cord mesenchymal stem cells (hUC-MSCs) in NOD. Cg-Prkdc scid IL2rg tm1Sug /JicCrl (NOG) mice. Methods Mice...

Introduction. Rosacea is a common chronic dermatological disease that negatively affects the quality of life of patients. Hypothesis. Combination therapy with 1% ivermectin solution alongside systemic treatment methods is more effective in reducing the severity of moderate to severe papulopustular rosacea symptoms compared with traditional treatmen...

Psoriasis is a chronic, inflammatory, immune-mediated skin disease affecting 1-3% of the adult population. It mainly involves the skin, nails, and joints. However, psoriasis can be associated with several comorbidities, including ocular complications. The most frequently reported pathologies are dry eyes syndrome, blepharitis, and uveitis. Being a...

Psoriasis is a chronic inflammatory skin disease characterized by an immune system response, manifesting in various forms including plaques, flexural lesions, wounds, pustules, and erythroderma. This condition affects individuals of all genders and impacts approximately 60 million people worldwide. The pathophysiology of psoriasis involves complex...

Purpose Atopic dermatitis (AD) is a chronic inflammatory skin disease that significantly compromises patients’ quality of life (QoL). The management of AD often focuses on objective clinical measures, overlooking its broader psychosocial and occupational impacts. This article explores how shared decision-making and the treat-to-target strategy can...

The shortage of medical personnel and the busy lives of modern people have increased the desire for the self-diagnosis of diseases, and the latest large-scale language models and image recognition technologies have the potential to meet this demand. In particular, skin-related diseases are one of the areas where symptoms are visually distinguishabl...

Acrokeratosis paraneoplastica is a rare and obligate paraneoplastic dermatosis most commonly associated with squamous cell carcinoma of the upper aerodigestive tract and lung. It has also been linked to adenocarcinomas of the lung, colon, and stomach. However, reports of its association with esophageal adenocarcinoma are exceedingly rare, with only...

Skin the outer covering of the body and is the largest organ of the body. The skin acts as protective barrier against physical, chemical and biological external agent. Skin disorders are among the most common health issues seen in clinical practice. Kushtha is a broad term which covers almost all the skin disease in Ayurveda. Kushtha is one of the...

Dear Editor, Pityriasis lichenoides (PL) is an inflammatory skin disease of unknown etiology. The clinical spectrum of pityriasis lichenoides encompasses febrile ulcer-necrotic Mucha-Habermann disease (FUMHD), pityriasis lichenoides et varioliformis acuta (PLEVA), and pityriasis lichenoides chronica (PLC). Phototherapy is an effective and well-tole...

Sweet syndrome is a rare inflammatory disease that typically presents with painful erythematous skin lesions and fever. Although the skin lesions are generally painful on clinical examination, in this case, they were noted to be painless without tenderness. Moreover, our case is unique in that this patient had myopericarditis, a rare extracutaneous...

Interleukin‐23 (IL‐23) is a dominant cytokine in psoriasis, a chronic inflammatory skin disease that severely diminishes patients' quality of life and reduces lifespan by up to 10 years. Despite therapeutic advancements, psoriasis remains a clinical challenge due to the absence of a definitive cure, treatment side effects, and substantial economic...

Background: Medical diagnosis for skin diseases, including leukemia, early skin cancer, benign neoplasms, and alternative disorders, becomes difficult because of external variations among groups of patients. A research goal is to create a fusion-level deep learning model that improves stability and skin disease classification performance. Methods:...

El xantogranuloma juvenil (XGJ) es la forma más frecuente de histiocitosis de células no Langerhans, un grupo de trastornos poco comunes que suelen aparecer en la edad pediátrica, principalmente en niños menores de cinco años. Su forma de presentación más frecuente es el compromiso cutáneo limitado, con presencia de pápulas o nódulos que adquieren...

Morbihan’s disease is a rare form of facial lymphedema often associated with chronic rosacea and other skin diseases such as acne. It presents as indurated erythematous plaques in the upper face, which can be challenging to treat. We report a 69-year-old male of Asian background with a 4-year history of facial swelling and redness, unresponsive to...

Background: Occupational skin dermatosis is of a significant concern among dental lab technicians due to their exposure to chemicals and materials used in dental prosthetics. These exposures can lead to various skin conditions, impacting the health and productivity of the workforce. To determine the prevalence, clinical features and associated fact...

Psoriasis is an immune-mediated inflammatory skin disease. IL-22, a proinflammatory cytokine, is implicated in psoriasis pathogenesis; however, there is currently no established biological treatment targeting IL-22 or its receptor, IL-22Rα. Alloferon is a short peptide that has an antiinflammatory effect on skin disorders; however, little is known...

Rosmarinic acid has noticed increasing application in cosmetology. It has been demonstrated to suppress elastase activity, hence inhibiting the degradation of elastin fibres. Moreover, it provides a purifying effect, diminishes sebum production, and reduces excessive bacterial proliferation, indicating its advantageous properties in the management...

Background: Diabetic dermatopathy (DD) is a common skin complication in patients with type 2 diabetes mellitus, associated with microvascular alterations. Its treatment is limited, but probiotics such as Lactobacillus plantarum have shown potential in modulating inflammation and improving skin health. This study evaluated the association between La...

Purple leaves in Indonesia can be used as an anti-inflammatory medication and laxative to treat hemorrhoids, rheumatism, boils, and skin diseases. Purple leaves are also used as free-radical antidotes. This was due to the presence of secondary metabolite compounds in purple leaves. The right extraction method determines the amount of flavonoids tha...

Background: Skin diseases are a source of significant health concern worldwide. Understanding its epidemiology is important for effective healthcare planning. In our hospital, this study is the first of its kind. This study examines the pattern and trends of skin diseases as seen in RSUTH. Methods: Medical records of patients seen in the dermatolog...

Psoriasis is a prevalent inflammatory dermatosis with possible systemic involvement. Metabolomics defines as an extensive study of all low molecular weight metabolites in human body which has recently led to better understanding of the pathogenesis of different disease. To evaluate the targeted lipidomics in sera of patients versus healthy controls...

Nanomaterials have revolutionized dermatology by enhancing drug delivery, skincare, and cosmetic applications. However, their increasing use raises concerns about possible toxic effects, especially in compromised areas. This review addresses knowledge gaps in nanomaterial penetration mechanisms, toxicological risks, and safety evaluations of diseas...

Water salinity is a serious crisis for south-western coastal region of Bangladesh. The consumption of saline water is linked to both immediate and long-term health effects, including cardiovascular diseases (CVD), diarrhoea, and abdominal discomfort. Under the present climate change scenario including sea level rise and salinity intrusion, the whol...

This study aimed to investigate the association between psoriasis and Life’s Essential 8 (LE8), which has demonstrated an inverse relationship with various chronic diseases, though its link to psoriasis remains unexplored. In this cross-sectional study, we analyzed data from the National Health and Nutrition Examination Survey (NHANES) conducted du...

There is growing evidence that ultraviolet-induced fluorescence (UVF) dermoscopy may improve diagnostic accuracy in non-neoplastic dermatoses, yet data on hair disorders are scarce. The aim of this observational retrospective study was to compare the accuracy of polarized dermoscopy and UVF-dermoscopy in characterizing and distinguishing scarring a...

Early and accurate identification of malignant skin diseases is critical to improving treatment outcomes and patient prognosis. Current diagnostic methods heavily rely on visual assessments by medical professionals, followed by biopsies for confirmation. These approaches can be subjective and require significant expertise, while access to specializ...

Skin conditions are becoming increasingly prevalent, and many of these ailments carry concealed risks that can elevate the likelihood of developing skin cancer. Given the low quality of images associated with such conditions, diagnosing these diseases traditionally required advanced medical expertise and specialized equipment. Furthermore, manually...

Atopic dermatitis (AD) and alopecia areata (AA) are chronic inflammatory skin diseases. While studies suggest a possible immune defense mechanism link between the two, the causal relationship remains unclear, and current methodologies have limitations. This study aims to investigate the causal relationship between AD and AA using genome-wide associ...

Introduction: Skin diseases significantly impact individuals' health and mental wellbeing. However, their classification remains challenging due to complex lesion characteristics, overlapping symptoms, and limited annotated datasets. Traditional convolutional neural networks (CNNs) often struggle with generalization, leading to suboptimal classific...

Skin diseases, a significant category in the medical field, have always been challenging to diagnose and have a high misdiagnosis rate. Deep learning for skin disease classification has considerable value in clinical diagnosis and treatment. This study proposes a skin disease classification model based on multi-scale channel attention. The network...

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with significant morbidity. Although cutaneous squamous cell carcinoma (cSCC) is a rare complication, it has serious consequences, particularly when associated with high-risk human papillomavirus (HPV) infections. This study examines two cases of HPV-16-in...

Skin diseases in melanin-rich skin often present diagnostic challenges due to the unique characteristics of darker skin tones, which can lead to misdiagnosis or delayed treatment. This disparity impacts millions within diverse communities, highlighting the need for accurate, AI-based diagnostic tools. In this paper, we investigated the performance...

Background/Objectives: Psoriasis is a chronic immune-mediated skin disease associated with several metabolic comorbidities. Metabolic dysfunction-associated steatotic liver disease (MASLD) is also linked to psoriasis, but evidence regarding the severity of this association remains inconclusive. This meta-analysis aimed to investigate the relationsh...

Dermatosis neglecta (DN) is a rare condition, often linked to psychosomatic disorders, with an unclear etiology. Chilblain lupus erythematosus (CHLE) constitutes a rare variant of cutaneous lupus erythematosus, frequently mistaken for idiopathic chilblain due to its chilblain-like lesions. To date, no instances of concurrent DN and CHLE occurring a...

Abstract Celiac disease, also known as gluten-sensitive enteropathy or non-tropical sprue, is immune related disorder of small bowel which is seen in genetically predisposed people and is due to permanent intolerance to wheat gliadins and other cereal prolamins. CD is often associated with extra- intestinal manifestations which includes several ski...

The use of dermatological images and convolutional neural networks (CNNs) to predict skin diseases is one of the most promising applications of data science to improve the diagnosis and treatment of skin diseases. The aim of this work was to achieve maximum accuracy and efficiency in skin disease prediction using dermatological images and CNN model...

Background: The skin is the largest organ that envelops the body and performs multiple functions, including temperature regulation, fluid balance, sensory perception, immune responses, and protection against ultraviolet damage. Drugs that reduce impurities in blood are called musaffiat-e-dams. The concept of musaffiat-e-dams (blood purifiers) and t...

One of the emerging paradigms in the diagnosis and severity assessment of skin disorders, particularly acne, on the face is the use of advanced digital technology (ADT) in skin disease monitoring. It is said to be a very prevalent issue that has to be looked at by experts in this day and age. Nonetheless, the traditional approach to acne diagnosis...

Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening autoimmune inflammatory skin disease. Tofacitinib is a non-selective, first-generation Janus kinase (JAK) inhibitor. Currently, both domestic and international reports regarding the use of tofacitinib mainly have primarily focused on the treatment of psoriasis vulgaris...

Purpose This review aims to outline the crucial role of IL-36 signaling in inflammatory skin diseases and summarize the therapeutic potential of spesolimab. Our goal is to provide insights into the off-label applications of spesolimab and future directions for its use in treating other challenging skin diseases. Materials and methods We conducted...

Dermatology diseases index fourth edition is first largest and most updated index of skin diseases in the world containing more than 5000 names ,and this index not just index so read to discover https://www.mediafire.com/folder/4sir5u7xu9rs2/Index

The relation between psychiatry and skin diseases is bidirectional. Despite proper drug compliance and adequate treatment, there are still recurrences. This has significant impact on mental health, which may cause psychiatric comorbidity, typically anxiety and depression. We have screened for the prevalence and severity of the same, to further unde...

The term ‘nonvenereal disease’ includes a heterogeneous group of disorders involving the genitalia, which are not transmitted sexually. Non venereal diseases are often responsible for physician’s diagnostic dilemma and considerable concern to the patient. Patients presenting with genital lesions often have apprehension of being suffering from vener...

Disorders of hyperpigmentation especially with facial involvement can result in tremendous psycho-social impact and are associated with poor quality of life. Mostly diagnosis is based clinically; the role of histopathology is limited by its invasive nature and reluctance on part of patient to undergo facial biopsy as well. Dermatoscopy is a non-inv...

O microbioma cutâneo refere-se ao conjunto de microrganismos que habitam a pele humana, desempenhando um papel fundamental na proteção contra patógenos, regulação do sistema imunológico e manutenção da saúde cutânea. Nos últimos anos, o entendimento sobre a influência do microbioma nas doenças de pele tem avançado, destacando sua relação com condiç...

E12. Dermatology diseases atlas with hyperlink to images is largest atlas of skin diseases in the world containing more than 2000 names with images folder hyperlinks ,more than 80 thousand images ,so read to discover pathology,nail, dermoscopy,and skin diseases https://www.mediafire.com/folder/43vl37mk5dgfo/Hyperlink

Skin diseases have a profound effect on the overall well-being of affected individuals, often associated with physical and mental anguish as well as social stigma. Traditional methods of treatment lack effectiveness in dealing with skin disorders and suffer from several limitations such as long treatment duration and high incidence of systemic side...

During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at the crossroads between autoimmunity and autoinflammation. Some patients may even present with autoinflammatory-related manifestations, including fever, hidradenitis suppurativa, other neutrophilic dermatoses, and an unusually high increase in inflammatory...

Streptococcus pyogenes leads to 500,000 deaths annually; many due to rheumatic heart disease in low-income settings. Limited understanding of natural protective immunity to S. pyogenes hinders vaccine development. We describe the evolution of serological profiles to conserved vaccine-antigens and type-specific M peptides from birth and throughout t...

Glutathione peroxidase 4 (GPX4) is a crucial antioxidant enzyme that plays a vital role in protecting cells from oxidative damage and lipid peroxidation. In the context of skin diseases, GPX4 serves as a key regulator of oxidative stress and inflammation, both of which are significant features of various skin conditions. By preventing lipid peroxid...

Skin disorders are common and require diagnosis and treatment in a timely manner. In traditional diagnostics, great demands are made on the time and interpretation of the results. To cope with this, we introduce YOLOv11, an enhanced deep learning model designed for skin disease detection and classification. The model integrates EfficientNetB0 as th...