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Publications related to Respiratory Medicine (4,887)
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Article
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Background There is a lack of early and precise biomarkers for personalized respiratory medicine. Breath contains an aerosol of droplet particles, which are formed from the epithelial lining fluid when the small airways close and re-open during inhalation succeeding a full expiration. These particles can be collected by impaction using the PExA ® m...
Article
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Pulmonary rehabilitation (PR) improves functional capacity, health-related quality of life (HRQoL) in COPD patients, and maintenance programmes are relevant in preserving those improvements. However, little is known about the structure of maintenance programmes after PR. We performed a systematic review and meta-analysis of experimental and quasi-e...
Article
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Mechanical ventilation has been a vital treatment for Covid-19 patients with respiratory failure. Lungs assisted with mechanical ventilators present a wide variability in their response that strongly depends on air-tissue interactions, which motivates the creation of simulation tools to enhance the design of ventilatory protocols. In this work, we...
Article
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Background With the advent of COVID-19, many healthcare workers (HWs) in Australia requested access to powered air purifying respirators (PAPR) for improved respiratory protection, comfort and visibility. The urgency of the response at our hospital required rapid deployment of innovative training to ensure the safe use of PAPRs, in particular, a vi...
Article
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Background: Despite growing evidence focusing on health inequalities in older adults, inequalities in medical compensation compared with younger adults and gender disparities of medical errors among older patients have received little attention. This study aimed to disclose the aforementioned inequalities and examine the disparities in medical erro...
Conference Paper
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Background: The tomato flu is a clinical variant of HFMD (hand foot and mouth disease). It is an acute viral illness that is caused by coxsackievirus (A16, A6, B) which belongs to the genus enterovirus (family picornaviridae). [1,2] As of now there are over 100 cases that have been reported in India. The first case was reported in Kerala, now cases...
Article
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Aims. To observe the clinical efficacy of self-made Lifei Dingchuan decoction combined with western medicine in the treatment of cough variant asthma (phlegm-heat accumulation in the lung syndrome). Materials and Methods. The clinical data of 90 patients with cough variant asthma who were hospitalized in the Department of Respiratory Medicine of ou...
Article
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Purpose: Serum electrolyte imbalances are highly prevalent in COVID-19 patients. However, their associations with COVID-19 outcomes are inconsistent, and of unknown prognostic value. We aim to systematically clarify the associations and prognostic accuracy of electrolyte imbalances (sodium, calcium, potassium, magnesium, chloride and phosphate) in...
Article
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jats:p>Cystic fibrosis (CF) is a life-shortening genetic disease, affecting multiple life domains including physical activity (PA). Although higher PA levels are associated with multiple health benefits, little insight exists on the PA level of people with CF (PwCF) compared to healthy peers. Evidence on the influencing factors ( i.e. correlates) o...
Article
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Background Digital adherence technologies hold promise to improve patient-centered tuberculosis (TB) monitoring, yet few studies have incorporated direct adherence monitoring or assessed patients’ experiences with these technologies. We explored acceptability, feasibility, and refinement needs of the TB Treatment Support Tools (TB-TSTs) interventio...
Article
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Metrics used in spirometry caught on in respiratory medicine not only because they provide information of clinical importance but also because of a keen understanding of what is being measured. The forced expiratory volume in 1 s (FEV1), for example, is the maximal volume of air that can be expelled during the first second of a forced expiratory ma...
Article
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Introduction: As millions of people worldwide recover from COVID-19, a substantial proportion continue to have persistent symptoms, pulmonary function abnormalities, and radiological findings suggestive of post-COVID interstitial lung disease (ILD). To date, there is limited scientific evidence on the management of post-COVID ILD, necessitating a c...
Article
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The diaphragm is the primary respiratory muscle, and its dysfunction predisposes patients to respiratory failure. Diaphragm function can be assessed by ultrasound measurement - Diaphragmatic Thickening Fraction (DTF). Respiratory viral infections (including SARS-CoV-2) can cause diaphragm dysfunction. Our case series follows three patients infected...
Article
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Purpose: To assess the relationship between the duration of systemic corticosteroid therapy and blood eosinophil counts in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). Patients and methods: This study included 292 patients with acute COPD exacerbations treated with daily intravenous injections of 40 mg/day m...
Article
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Xu-Dong Shen,1 Hua-Sheng Zhang,1 Rui Zhang,1 Jun Li,1 Zhi-Gang Zhou,1 Zhi-Xian Jin,2 Yin-Jia Wang1 1Department of Critical Care Medicine, Calmette Hospital Affiliated to Kunming Medical University, Kunming, 650011, People’s Republic of China; 2Department of Respiratory Medicine, Calmette Hospital Affiliated to Kunming Medical University, Kunming, 6...
Article
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Hatsuyo Takaoka,1 Hideki Terai,1 Katsura Emoto,2 Lisa Shigematsu,1 Fumimaro Ito,1 Ayaka Saito,1 Masahiko Okada,1 Keiko Ohgino,1 Shinnosuke Ikemura,3 Hiroyuki Yasuda,1 Ichiro Nakachi,4 Ichiro Kawada,1 Koichi Fukunaga,1 Kenzo Soejima3 1Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan; 2Departmen...
Article
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Adenocarcinoma of the lung along with malignant pleural effusion is an autonomous predictor of decreased survival, thus the main focus of the clinician should be on palliative care. In this case report, we describe chemotherapy, palliative care physiotherapy, and the necessary pulmonary rehabilitation approaches that were used for our patient. It o...
Article
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Introduction Drug-resistant tuberculosis (DR-TB) is a global public health problem. Patients suffer for months if undiagnosed or treated inadequately, transmitting DR-TB in the community before succumbing to the disease. Early diagnosis, prompt treatment initiation and completion play a significant role in treatment success. However, extended regim...
Article
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Objective To establish the most effective and best tolerated dose of caffeine citrate for the prevention of intermittent hypoxaemia (IH) in late preterm infants. Design Phase IIB, double-blind, five-arm, parallel, randomised controlled trial. Setting Neonatal units and postnatal wards of two tertiary maternity hospitals in New Zealand. Participa...
Article
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: The first laboratory‐confirmed case of the novel coronavirus (COVID‐19) was reported in India on 30 January 2020. Since then, there has been exponential growth in cases, with India now ranking second in the global burden of COVID‐19. The novel coronavirus disease (COVID-19) is the greatest burden faced by the healthcare system at present. A major...
Article
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Background Bronchoalveolar lavage (BAL) is a key tool in respiratory medicine for sampling the distal airways. BAL bile acids are putative biomarkers of pulmonary microaspiration, which is associated with poor outcomes after lung transplantation. Compared to BAL, large airway bronchial wash (LABW) samples the tracheobronchial space where bile acids...
Article
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Background: Although short-acting β 2-agonist (SABA) overuse is associated with poor treatment outcomes , data on SABA use in the Middle East are lacking. Research design and methods: In this cross-sectional study in patients (aged ≥12 years) with asthma, data on disease characteristics and asthma treatments were collected from the Middle Eastern c...
Article
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Objective: To explore the application effect and prognostic benefits of whole-course high-quality nursing in lung cancer patients after surgery. Methods: Sixty patients with lung cancer who underwent surgical treatment in the Department of Respiratory Medicine from April 2020 to July 2021 were recruited and assigned to receive either conventiona...
Article
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Chronic obstructive pulmonary disease (COPD) has turned out to be the third driving reason of death worldwide today. The pharmacological drugs accessible to treat the COPD patient have expanded in the course of last decade. Patient with advance COPD are particularly at risk of poor result and present trouble on medical services. Combination of bron...
Article
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Objective Epipericardial fat necrosis (EFN) has been considered to be a rare cause of acute chest pain, and especially important for emergency physicians. Chest computed tomography (CT) is often used for the diagnosis of EFN after excluding life-threatening states, such as acute coronary syndrome and pulmonary embolism. While the proportion of EFN...
Article
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Background: The application of exercise therapy (ET) in chronic obstructive pulmonary disease (COPD) is generating increasing clinical efficacy and social-economic value. In this study, research trends, evolutionary processes and hot topics in this field are detailed, as well as predictions of future development directions. Methods: Search for lite...
Article
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Objectives Obstructive sleep apnoea (OSA) is a condition wherein collapse of the upper airway during sleep results in decreased or complete cessation of airflow. The association of OSA with increased cardiovascular morbidity, mortality, and various cardiovascular risk factors is known for a long time. Metabolic syndrome a cluster of metabolic abnor...
Article
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The correct use of medicine administration devices is pivotal for optimal drug therapy in children. Little is known about end users’ perspectives on administration device use. Thus, the aim of this study was to conduct a survey to gain information and opinions from caregivers and children regarding the usability of paediatric medicine administratio...
Article
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Omalizumab is a monoclonal antibody which targets immunoglobulin E. It is approved as an add‐on therapy for children with severe allergic asthma. Assessment of endotype and phenotype is necessary in order to correctly identify those patients who are most likely to respond to omalizumab. Children with severe asthma represent a complex heterogeneous...
Article
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Objectives: Pulmonary hypertension (PH) is a life-shortening disease associated with early mortality and high morbidity. With advancements in medical treatment, people are living longer with the disease and research is now needed to explore variables that help to enhance patient-reported outcomes. This study investigated the coping strategies of in...
Article
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A young man known with autosomal dominant hyper IgE syndrome and changes on his chest radiograph was presumed to be infected with Aspergillus and treated with antifungal medicine for 11 months without effect. Positron emission tomography/computed tomography imaging was suggestive of Aspergilloma but bronchoalveolar lavage cultures, cytology as well...
Article
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Introduction: In India, the daily weight-based, Fixed Dose Combination (FDC) Antituberculosis Treatment (ATT) regime under the National Tuberculosis Elimination Programme (NTEP) was introduced, replacing the previous intermittent regime with the aim of improving compliance, decreasing Adverse Drug Reactions (ADRs) and thus ultimately translating to...
Article
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The COVID-19 pandemic has caused devastating economic and social disruption. This has led to a nationwide call for models to predict hospitalization and severe illness in patients with COVID-19 to inform the distribution of limited healthcare resources. To address this challenge, we propose a machine learning model, MedML, to conduct the hospitaliz...
Article
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Background: Clinical pharmacists play a significant role in clinical practice, but their work in the clinical pathway (CP) of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) remains undefined. Methods: This prospective study included patients who met the discharge criteria during hospitalization at the department of respira...
Article
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A mixed breed dog was treated for severe hemolytic anemia secondary to Babesia canis infection. Within 14 hours of hospitalization, the dog developed respiratory distress and hypoxemia. The patient improved with lung‐protective mechanical ventilation and neuromuscular blockade. The dog survived to discharge and was reportedly healthy at three‐month...
Article
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Background: The prevalence of anticoagulant therapy-associated hemorrhagic complications in hospitalized patients with pulmonary embolism (PE) has been scarcely investigated. Aim: To evaluate the prevalence of hemorrhages in hospitalized PE patients. Methods: The Information System "ASKLIPIOS™ HOSPITAL" implemented in the Respiratory Medicine...
Article
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Introduction: Tracheostomy is one of the most common surgical strategies in intensive care units (ICU) and provides relevant clinical benefit for multiple indications. However, the complications associated with its use range from 5 to 40% according to different series. The risk of these complications could be reduced if fixation strategies and ali...
Article
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RESUMEN El asma grave constituye un síndrome heterogéneo con diversas variantes clínicas y representa en muchas ocasiones, una enfermedad compleja con necesidad de un abordaje especializado y multidisciplinar, así como la utilización de múltiples fármacos. La prevalencia del asma grave varía de un país a otro, y se estima que el 50% de estos pacien...
Article
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Nasopharyngeal teratomas are rare and represent only 2% of all teratomas. They can lead to an embryopathogenic mechanical obstacle responsible for a cleft palate with few reported cases of this association in the literature. We report the case of a 14‐month‐old girl with this atypical association. Teratomas are the most common congenital tumors, wh...
Article
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We report a child with persistently low oxygen saturations (SpO2 90%–92%) [normal SpO2 > 98%], with delayed diagnosis due to the co‐existing congenital pulmonary airway malformation with possible arterio‐venous malformation. The diagnosis was only achieved after low oxygen saturations incidentally discovered from the child's father. The eventual ca...
Article
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Hong Duc Pham,1,2 The Anh Nguyen,3 Thi Giang Doan,1,2 Van Giang Bui,2,4 Thanh Van Phan-Nguyen5 1Radiology Department, Saint Paul Hospital of Ha Noi, Ha Noi, Vietnam; 2Radiology Department, Hanoi Medical University, Ha Noi, Vietnam; 3Department of Respiratory Medicine, Huu Nghi Hospital, Hanoi, Vietnam; 4Radiology Centre, National Cancer Hospital, H...
Article
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Background: The change in FEV1 after administration of a short-acting bronchodilator has been widely used for diagnosis of obstructive airway diseases. Many factors can influence the post bronchodilator reversibility. Aim: The aim of the present study was to estimate the presence of reversibility among the patients of obstructive airway disease...
Article
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Emily O’Reilly,1 Deborah Casey,1 Hisham Ibrahim,1 Alice McGrath,1 Tomás McHugh,1 Punitha Vairamani,1 Jill Murphy,1 Barry Plant,1,2 Desmond M Murphy1,2 1Department of Respiratory Medicine, Cork University Hospital, Cork, Ireland; 2Health Research Board Clinical Research Facility, University College Cork, Cork, IrelandCorrespondence: Desmond M Murphy...
Research
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Aims To describe a) the history and evolution of newborn bloodspot screening (NBS) tests for cystic fibrosis (CF) in the United Kingdom (UK) and b) the developments which led to this being adopted as part of a national UK programme. Methods The history and evolution of the newborn screening programme for cystic fibrosis was reviewed and summarised...
Article
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Objective: The Respiratory Health Strategic Clinical Network (RHSCN) was launched to facilitate respiratory and sleep health through implementation of innovative, patient-centred, evidence-informed coordinated services in Alberta. In collaboration with project partners, the RHSCN aimed to determine the respiratory research priorities for Alberta....
Article
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Introduction Multidrug-resistant tuberculosis (MDR-TB) remains a major public health problem globally. Long, complex treatment regimens coupled with frequent adverse events have resulted in poor treatment adherence and patient outcomes. Smartphone-based mobile health (mHealth) technologies offer national TB programmes an appealing platform to impro...
Article
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A man in his 40s was admitted to his local hospital 6 days after the first vague symptoms of COVID-19. His general condition deteriorated, and he was treated in the intensive care unit but did not require mechanical ventilation. During his recovery, he experienced a cough spell, after which his dyspnoea recurred and rapidly increased. CT pulmonary...
Article
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Using data of Chinese immigrants extracted from the Belgian National Register registering a cohabitation or marriage between 2005 and 2015 (N = 3945), this study aims to advance the understanding of cohabitation among disadvantaged groups in local marriage markets. From the difference in prevalence of cohabitation between Chinese men and women, we...
Article
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OBJECTIVES Our goal was to identify the inferior mesenteric artery diameter and number of patent lumbar arteries causing a significant type 2 endoleak to develop after infrarenal endovascular aneurysm repair. MATERIAL AND METHODS Included were patients who underwent infrarenal endovascular aneurysm repair between April 2002 and January 2017. Patie...
Article
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Objectives Poor control of asthma in the majority of patients could be partly due to their lack of knowledge concerning disease management, its triggering agents and when to seek advice from the healthcare provider. This study aims to assess the impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patien...
Article
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Background Coronavirus disease (COVID-19) has induced an urgent need to train medical students not only in infection prevention control but also in the treatment of infectious diseases, including COVID-19. This study evaluates the impact of simulated clinical practice with peer role-plays and a lecture on clinical education for COVID-19. Methods T...
Article
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Según la encuesta nacional de salud de España del año 2017, el 22,1% de los habitantes entre 15-64 años se consideran fumadores diarios, correspondiendo un 25,6% a hombres y un 18,8% a mujeres, y siendo exfumadores un 32,2% de los hombres y un 18,02% de las mujeres. Aunque es bien conocido que el tabaquismo es un factor de riesgo para el desarrollo...
Article
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Background Effective lung protective ventilation requires reliable, real-time estimation of lung volume at the bedside. Neonatal clinicians lack a readily available imaging tool for this purpose. Objective To determine the ability of lung ultrasound (LUS) of the dependent region to detect real-time changes in lung volume, identify opening and clos...
Article
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Frente a la pandemia del CoVID-19, resulta fundamental establecer estrategias manteniendo distanciamiento social, que permitan educar a profesionales de la salud sobre aspectos relacionados con SARS-CoV-2. La Sociedad Chilena de Neumología Pediátrica creó un E-learnig de contingencia de acceso libre. Objetivo: Describir las características del curs...
Article
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The COVID-19 pandemic crisis, among so many social, economic and health problems, also brought new opportunities. The potential of telemedicine to improve health outcomes had already been recognised in the last decades, but the pandemic crisis has accelerated the digital revolution. In 2020, a rapid increase in the use of remote consultations occur...
Article
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Objective This study aimed to establish a pediatric lower respiratory tract infections (PLRTIs) database based on the structured electronic medical records (SEMRs), to provide a brief overview and the usage process of the SEMRs and the database.Methods All the medical information is recorded by a clinical information system developed by Eureka Syst...
Article
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Peter Alter,1 Jan Orszag,2,3 Emiel FM Wouters,4,5 Claus F Vogelmeier,1 Rudolf A Jörres2 1Department of Medicine, Pulmonary and Critical Care Medicine, Philipps-University of Marburg (UMR), Germany, Member of the German Center for Lung Research (DZL), Marburg, Germany; 2Institute and Outpatient Clinic for Occupational, Social and Environmental Medic...
Article
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Objective To evaluate the association between having concomitant chronic obstructive pulmonary disease (COPD) or asthma, and in-patient mortality and post-discharge management among patients hospitalised for acute heart failure (HF). Setting Data were obtained from patients enrolled in the National Heart Failure Audit. Participants 217 329 patien...
Article
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Objectives The Conversation, Understand, Replace, Experts and evidence-based treatment (CURE) project implemented an evidence-based intervention that offers a combination of pharmacotherapy and behavioural support to tobacco-dependent inpatients. Understanding key characteristics of CURE’s implementation strategy, and identifying areas for improvem...