Recurrence - Science topic

Metacarpal bone reconstruction renders a surgical challenge. We describe a case using 3D printing assisted medial femoral condyle flap for extensive metacarpal reconstruction after wide resection of a large giant cell tumor recurrence. Thus, the length and stability of the entire third ray could be restored without any tumor recurrence.

In this case report, we describe the novel use of a permanent indwelling catheter (PiC) in the management of refractory malignant pericardial effusion (PE). The patient had disseminated lung cancer and was hospitalised repeatedly with circulatory collapse due to malignant PE despite treatments with pericardiocentesis (PCC) and a pericardial window...

Image-guided percutaneous ablation techniques represent an attractive local therapy for the treatment of colorectal liver metastases (CLM) given its low risk of severe complications, which allows for early initiation of adjuvant therapies and spare functional liver parenchyma, allowing repeated treatments at the time of recurrence. However, ablatio...

Background Basal cell carcinoma (BCC) is the most common cancer worldwide. Most of BCCs can be detected in the early stages and are generally well controlled with local resection. Despite the high incidence of BCC, metastasis is rarely observed. Metastatic BCCs generally have an aggressive phenotype and are refractory to conventional treatment. Ca...

Acquired resistance to BRAF/MEK-targeted therapy occurs in the majority of melanoma patients that harbor BRAF mutated tumors, leading to relapse or progression and the underlying mechanism is unclear in many cases. Using multiplex immunohistochemistry and spatial imaging analysis of paired tumor sections obtained from 11 melanoma patients prior to...

Osteosarcoma and Ewing sarcoma are the most common bone sarcomas in children. Their clinical presentation is very variable depending on the age of the patient and tumor location. MRI is the modality of choice to assess these bone sarcomas and has an important function at diagnosis and also for monitoring recurrence or tumor response. Anatomic seque...

Background Guidelines to standardize treatment and follow-up strategies in pneumomediastinum cases are lacking. The aim of the study was to evaluate the etiology in pneumomediastinum cases and the results of treatment and follow-up. Results Nineteen patients with pneumomediastinum who were followed up in our clinic between 2015 and 2020 comprised...

Background Solitary fibrous tumor (SFT) is a rare tumor of mesenchymal origin and accounts for < 2% of all soft tissue masses. Although SFT has been identified in multiple anatomic locations and can grow anywhere in the body, intrapulmonary SFT are rare. Case presentation In this report, we presented a rare case of intrapulmonary solitary fibrous...

Background Clostridioides difficile infection (CDI) is associated with high recurrence rates impacting health-related quality of life (HrQOL). However, patient-reported data are lacking particularly in the outpatient setting. We assessed changes in HrQOL over time in patients treated with bezlotoxumab at US infusion centers and determined clinical...

Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We underline the beneficial impact of oral propranolol therapy on QoL of patients with infantile hemangiomas (IH) and of their relatives. A specific...

Background There are several genes associated with ovarian cancer risk. Molecular changes in borderline ovarian tumor (BOT) indicate linkage of this disease to type I ovarian tumors (low-grade ovarian carcinomas). This study determined the prevalence and association of mutations in BRCA1, BRCA2, PALB2, RAD51C , and CHEK2 with the risk of BOTs. Met...

Background There are currently no methodological studies on the performance of the statistical models for estimating intervention effects based on the time-to-recurrent-event (TTRE) in stepped wedge cluster randomised trial (SWCRT) using an open cohort design. This study aims to address this by evaluating the performance of these statistical models...

Background A Rathke’s cleft cyst is a benign intrasellar cystic lesion, with suprasellar extension reported in a few cases. An entirely suprasellar Rathke’s cleft cyst without any intrasellar component, though previously reported, is rare. Case presentation We report a case of an entirely suprasellar Rathke’s cyst in a 25-year-old female presentin...

Ibrutinib is effective in the treatment of relapsed/refractory (R/R) marginal zone lymphoma (MZL) with an overall response rate (ORR) of 48%. However, factors associated with response (or lack thereof) to ibrutinib in R/R MZL in clinical practice are largely unknown. To answer this question, we performed a multicenter (25 US centers) cohort study a...

Teams composed of human and machine members operating in complex task environments must effectively interact in response to information flow while adapting to environmental changes. This study investigates how interpersonal coordination dynamics between team members are associated with team performance and shared situation awareness in a simulated...

Background Hemorrhoidal disease most commonly manifests itself with chronic rectal bleeding and, in its most severe and refractory forms, may lead to chronic anaemia with the need for recurrent blood transfusions. The main pathogenetic mechanism involved seems to be arterial hyperflux in the terminal branches that supply the hemorrhoidal plexus. It...

Systemic chemotherapy with multiple drug regimens is the main therapy option for advanced gastric cancer (GC) patients. However, many patients develop relapse soon. Here, we evaluated the therapeutic potential of targeting interleukin-8 (IL8) to overcome resistance to chemotherapy in advanced GC. RNA sequencing revealed crucial molecular changes af...

Heterotopic mesenteric ossification (HMO) is a rare condition which usually affects male patients. Its defining feature is hyperdense ossification in the mesentery, usually following surgery or trauma. Due to potentially serious complications that can arise from HMO, it is essential to recognize it in its nascent stages. In this case study, a 65-ye...

Background Vaccines against SARS-COV2 have been crucial in efforts against COVID19, yet there have been reports of pericarditis following vaccination with mRNA-based vaccines. Methods We questioned consecutive patients with a history of acute pericarditis (AP) evaluated in the pericardial disease clinic during 3–11/2020 in a single tertiary center...

For an integer $$q\ge 2$$ q ≥ 2 , a q -recursive sequence is defined by recurrence relations on subsequences of indices modulo some powers of q . In this article, q -recursive sequences are studied and the asymptotic behavior of their summatory functions is analyzed. It is shown that every q -recursive sequence is q -regular in the sense of Allouch...

Although the pathogenesis of immune thrombocytopenia is not fully known, oxidative stress is one of the etiological causes. Copper and zinc are elements in the antioxidant system, and their deficiency causes oxidative stress. We aimed to determine the serum copper and zinc levels and their effects on the response to treatment in patients with immun...

Rowland and Zeilberger devised an approach to algorithmically determine the modulo pr\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p^r$$\end{document} reductions of v...

A new procedure to find the ultimate ruin probability in the Cramér-Lundberg risk model is presented for claims with a mixture of m Erlang distributions. The method requires to solve an m order linear recurrence sequence, which translates into finding the roots of an m-th degree polynomial and solving a system of m linear equations. We here study o...

The development of cloud-connected Internet of Things (IoT) systems is becoming more and more affordable, even to novice programmers, thanks to dedicated cloud platforms that already integrate the core functionality needed by an IoT system. In this context, a growing number of IoT systems are being developed and deployed on open networks, often wit...

The q-rational numbers and the q-irrational numbers were introduced by Morier-Genoud and Ovsienko. In this paper, we focus on q-real quadratic irrational numbers, especially q-metallic numbers and q-rational sequences which converge to q-metallic numbers, and consider the radiuses of convergence of them when we assume that q is a complex number. We...

Rosacea is a common chronic facial inflammatory skin disease. However, treatment for “difficult-to-treat rosacea” cases has not been established. This 48-week, prospective, observational study analyzed patients who underwent three non-insulated fractional microneedle radiofrequency (NFMRF) sessions at 2-month intervals. Therapy efficacy, epidermal...

We establish the existence of an involution on tabloids that is analogous to Schützenberger’s evacuation map on standard Young tableaux. We find that the number of its fixed points is given by evaluating a certain Green’s polynomial at q=-1\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amss...

Considering a so-called square k-zig-zag shape as a part of the regular square grid as a k-zigzag digraph, we give values to its vertices according to the number of the shortest paths from a base vertex. It provides several integer sequences, whose higher-order homogeneous recurrences are determined by the help of a special matrix recurrence. We al...

Part 4 deals with the calculation of the coefficients of atomic orbitals contributing to molecular orbitals of benzene pointing out the limitations of using the cofactors method and solutions.. Part 5 deals with the calculations of coefficients for [14] annulene using D2h symmetry. In addition to the cofactors method, a linear equations method is u...

The key challenge of sequence representation learning is to capture the long-range temporal dependencies. Typical methods for supervised sequence representation learning are built upon recurrent neural networks to capture temporal dependencies. One potential limitation of these methods is that they only model one-order information interactions expl...

Tunneled indwelling pleural catheters (IPCs) are frequently used to palliate symptomatic dyspnea due to recurrent pleural effusions. The drainage valve of IPCs is an important component of the catheter as fracture of the valve leads to malfunctioning of the IPCs. Replacement of the catheter includes risks such as pain, infection, pneumothorax, and...

Purpose There is paucity of data in management of recurrent and expanding subdural hematomas (SDH) within the pediatric population, who are otherwise not surgical candidates. Middle meningeal artery (MMA) embolization has been utilized minimally in this population and here, we explore the utility of this procedure in a 15-month-old-child, along wit...

In recent years, with the construction and development of smart cities, text recognition in building images can not only achieve geolocation but also provide guiding significance for GIS mapping and automatic updating. Since buildings have different orientations, angles and shapes, it is difficult to recognize textual features in images. With the w...

High-risk non-muscle-invasive bladder cancer (NMIBC) has a heterogeneity and intensive surveillances after transurethral resection of bladder tumor (TURBT) are major factors of increased costs. Therefore, we aimed to develop optimized surveillance protocols based on the risk score-based substratifications to improve surveillance costs. We retrospec...

As one of the most common congenital neck masses, thyroglossal duct cyst (TGDC) developed from the residual ductal epithelial cells in any remnants of thyroglossal duct. However, the reports of double TGDCs were rare. A 60-year-old male was referred to our department because of the presentation of an anterior neck mass. Only a hypodense oval mass i...

Alopecia areata (AA) is a patchy autoimmune nonscarring hair loss. Various pathophysiological explanations are described with immune dysregulation being the most well established. In this report, we describe a 63-year-old lady with AA recurrence, in the form of AA universalis, after 32 years of remission, following administration of severe acute re...

\noindent In this article, we determine all the integers $c$ having at least two representations as difference between two linear recurrent sequences. This is a variant of the Pillai's equation. This equation is an exponential Diophantine equation. The proof of our main theorem uses lower bounds for linear forms of logarithms, properties of continu...

We present a novel Recurrent Graph Network (RGN) approach for predicting discrete marked event sequences by learning the underlying complex stochastic process. Using the framework of Point Processes, we interpret a marked discrete event sequence as the superposition of different sequences each of a unique type. The nodes of the Graph Network use LS...

Doege–Potter syndrome is a rare paraneoplastic syndrome characterized by non-islet cell tumor hypoglycemia secondary to a solitary fibrous tumor. Doege–Potter syndrome always presents with recurrent fasting hypoglycemia, which can occasionally be life-threatening. The best choice of treatment for Doege–Potter syndrome and solitary fibrous tumor is...

Rational Stress is a major trigger for drug relapse in humans and animal models, even after prolonged abstinence. However, animal models for stress-induced relapse were criticized for the lack of predictive and face validity. Objectives Here we investigated the effect of acute food deprivation stress in a novel stress-induced relapse model using v...

We demonstrate the first Recurrent Neural Network architecture for learning Signal Temporal Logic formulas, and present the first systematic comparison of formula inference methods. Legacy systems embed much expert knowledge which is not explicitly formalized. There is great interest in learning formal specifications that characterize the ideal beh...

In this work, we propose an efficient computational technique for a recognized three-layer beam model which is described by a third-order linear ordinary differential equation. By using the Mickens' methodology, an exact finite difference (EDS) scheme for this model is constructed. The EDS scheme provides an explicit recurrence formula to compute t...

Background Pulmonary vein (PV) reconnection after radiofrequency (RFC) or cryoballoon (CB) pulmonary vein isolation (PVI) is common. Method We report a single-center experience of 156 patients who underwent a redo procedure-ablation strategy for recurrent atrial fibrillation (AF) in a reverse sequence after a failed index RFC or CB PVI. Results A...

Independientemente del uso dogmático de los términos griegos ora para dar a conocer la fe en la cultura griega, ora para dar sustento teórico a las muchas reflexiones que hicieron frente a las herejías, un potente y agudo deseo de sabiduría que se convirtió en deseo o pasión por Dios con implicaciones éticas y místicas resulta análogo a una concepc...

Let $\mathscr{P}_\mathbb{Q}=\{ \alpha^n \; : \; \alpha \in \mathbb{Q}, \; n \ge 2\}$ be the set of rational perfect powers, and let $S \subseteq \mathscr{P}_\mathbb{Q}$ be a finite subset. We prove the existence of a polynomial $f_S \in \mathbb{Z}[X]$ such that $f(\mathbb{Q}) \cap \mathscr{P}_\mathbb{Q}=S$. This generalizes a recent theorem of Gajo...

Epilepsy is the second most common neurological disease after Alzheimer. It is a disorder of the brain which results in recurrent seizures. Though the epilepsy in general is considered as a serious disorder, its effects in children are rather dangerous. It is mainly because it reasons a slower rate of development and a failure to improve certain sk...

Recently, Kim-Kim introduced the degenerate r-Bell polynomials and investigated some results which are derived from umbral calculus. The aim of this paper is to study some properties of the degenerate r-Bell polynomials and numbers via boson operators. In particular, we obtain two expressions for the generating function of the degenerate r-Bell pol...

Carbonic anhydrase VA deficiency is a recently described inherited cause of paediatric hyperammonaemia. Most published cases describe patients with only one episode of hyperammonaemia whilst others report patients who had up to three metabolic crises with the first invariably being the most severe. We describe a patient with carbonic anhydrase VA d...

Objetivo: analizar las estrategias para obtener recursos económicos que utilizan las unidades domésticas campesinas, cuya actividad principal es la agricultura familiar y la comercialización de sus productos en el mercado de Santiago Mixquitla en San Pedro Cholula, Puebla. Metodología: se aplicó una encuesta a treinta comerciantes y una entrevista...

Fibrolipoma is one of the variants of lipoma. Lipoma is a rare benign tumour of upper aerodigestive tract, but occur commonly in limbs and trunk. We present a 65 year old man who presented with huge recurrent fibrolipoma of the larynx causing upper airway obstruction which recurred five (5) years after an initial endoscopic excision of a benign lar...

Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus. Its prevalence and recurrence rates are high. While there are multiple treatment options for condyloma acuminatum, no single therapy form is effective in achieving complete remission. Photodynamic therapy (PDT) was shown to be very promising as a treatment...

Background: The prevalence of dermatophytes infections or Tinea or Ringworm is worldwide. Due to the resistance to conventional therapy and the high chance of recurrence of these infections, there is a need to develop an alternative therapy like Homoeopathy. Homoeopathic medicines are broadly used for various fungal infections with gentle and perma...

Report topic: Estimation of Lithium-ion batteries SOC based on Attention-GRU(Gated Recurrent Unit) Reporter: Qingyun Ma Report time: 21:00-21:10 Aug. 9, 2022 (Beijing time) Venue: Tencent conference Meeting link: https://meeting.tencent.com/dm/Gr5tGbY0h4iX Meeting number: 809 5352 9957 Members of the ministerial organizations are requested to atten...

Dermatofibrosarcoma protuberans (DFSP) is a fibrohistiocytic tumor characterized by a high risk of local recurrence but a low risk of metastasis. A small subpopulation of DFSP undergoes fibrosarcomatous (FS) change, and approximately 15%‐57% of cases of DFSP with FS change metastasizes, leading to a poor prognosis. In this report, a case of metasta...

Ayurveda is one of the oldest recognized system of medicine with the rich heritage of fundamental concepts. One of the most important concept among all is Pathya-apathya Sankalpana. The management of any vikaar with the help of Aushadh-kalpana can give more than the expected result only when it is accompanied with Pathya-apathya kalpana, as it not...

Background Outcomes of partially covered self-expandable metal stents (SEMS) as an additional stent after recurrent duodenal obstruction (RDO) have not been elucidated. In this study, we compared outcomes of partially covered and uncovered SEMS placement after RDO in patients with malignant duodenal obstruction and explored factors affecting re-rec...

Background Refractive error detection is a significant factor in preventing the development of myopia. To improve the efficiency and accuracy of refractive error detection, a refractive error detection network (REDNet) is proposed that combines the advantages of a convolutional neural network (CNN) and a recurrent neural network (RNN). It not only...

To investigate the diagnostic value of dermoscopy in defining the tumor margin of basal cell carcinoma (BCC) for the appropriate surgical margin. A total of 107 BCC patients were enrolled for this study. The tumor boundaries were observed by naked eye and dermoscope respectively, and 5mm outward was used as surgical margin according to the dermosco...