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Reconstructive Surgery - Science topic

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Dear all,
I am currently searching for a topic to write my thesis on but to no avail. Preferably I would like the argument to be centered around plastics and reconstructive surgery since it is a specialty I would like to pursue after medical school.
The topics that interest me the most in plastic and reconstructive surgery are :
- Wound healing
- Vascularised Composite grafts
- Craniofacial surgery
Regarding these topics, I would like to know what within these arguments are trending questions.
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Nanotecnology and reconstructive surgery
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Among children sufering from aero-disgestive conditions, it is incresasingly common to use surgical procedures as a treatment. My review of the literature is that the population is unclear. Do you have better sources than I've been able to find?
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Laryngotracheal reconstruction is a surgical procedure that carries a risk of side effects including; infection, collapse lung, endotracheal tube, voice and swallowing difficulties.
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Surgeons who treat patients with vulvar malignancy should be aware of the serious defect (Fig) following radical vulvectomy, which need immediate reconstruction.
Numerous vascularized flaps have been designed and validated for obliterating the dead space and closing the vulvoperineal skin defect. But the reconstructive surgery with flaps is somewhat like a way that rob Peter to pay Paul.
I had systematically searched the relevant articles in Pubmed with the search strategy and selection criteria “vulvar malignancies”; “vulva”, “vulvar”, “vulval”;“vulvectomy” ; “vulvar reconstruction” combined with“vulvovaginal reconstruction”; “quality of life”, no paper regarding the procedure of vulvar transplantation was found.
Is it possible to perform allogeneic vulvar transplantation with anastomosis of the internal pudendal artery aiming at recovering an acceptable cosmetic appearance.
Thank you for your attention.
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Hamid Asmouki Dear Dr. Hamid Asmouki, Many thanks for your comment, I agree with your suggestion. As the skin defect is close to anus opening, colostomy should be considered before reconstructive surgery or vulvar transplantation for avoiding the postoperative infection.
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A 17 year old male presented with psychotic symptoms, trichotillomania and intellectual disability and likely FASD . On routine CT scan he was found to have a large fibro- osseous growth extending from the pterigoid process , sphenoid sinus to zygomatic bone, which was asymptomatic. He also was born with atrial septal defect and had reconstructive surgery. What would be the etiopathology of such finding and what would be it’s prognosis.
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fibrous dysplesia Prajjita Bardoloi rajjita Bardoloi
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A 59-yr-old male, a victim of an road traffic accident, sustained polytrauma, undergone multiple sessions of definitive and reconstructive surgeries and now waiting in the ward for another surgical session. One of his dehiscent wound is on continuous suction and causing a little pain. He can not sleep at night without introducing a Diclofenac suppository. He has to take about 400 suppositories within last 3 months! What is the explanation and remedies please?
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Diclofan is not a addiction drugs but I think the patient habits specially suppositoy as a roat of administration  is a main cause of addiction as your description!!!
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Patients who do not fit the hearing aids and have bad results of reconstructive surgery and who want to test BAHA.
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Successful bone-anchored hearing aid implantation in a patient with osteogenesis imperfecta
Article in The Journal of Laryngology & Otology 129(11):1-4 · September 2015
DOI: 10.1017/S0022215115002510
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Hi,
I want to do experiment with splinted wound model in rats.
What kind of glue do  you use to stick silicone disks? Do these disks still on skin as long as 2 week?
Thank you.
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Crazy glue is the clear glue that dry up very fast (Cyanoacrylate) you need to apply very little on the silicone disk (aka = o-ring) and hold the ring down for 30 to 60 seconds so the skin will attache to the ring. I recommend to use 6 or 8 interrupted cruciate suture knots for holding the o ring in place for the 2 weeks.
Crazy glue @
Silicone ring in amazon
cruciate suture knot
If you want more info feel free to contact me.
Diego
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Autologous bone grafts
Xenografts
Allografts
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The best thing is autologous bone graft from calvarium, with minimal rate of absorption.I have done many with little absorption.
Regards
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Our team is looking for evidence that muscle recruitment patterns are altered following ACL reconstructive surgery which may effect scores on tests such as the Bunkie test, outlined by de Witt and Venter in the attached publication.
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The author Greg Myer I am sure will know and has a lot of references about that topic. 
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I have done microneedling for 19 years and I always apply vitamin A, C and E to the skin immediately after the treatment. I have never seen a reaction ever and my experience covers about 2000 personal cases and in excess 10,000 when including my associates using the same regime.   The product we use is Environ vitamin ACE Oil which has no added preservatives, colourants or perfumes.  This is the same oil as used by Zeitter et al in their research at Hannover Medical School to test needling skin at weekly intervals.   In their research the vitamin A,C E oil vastly increased the magnitude of the result.
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  • I think cleaning the skin properly with a suitable anti septic and anti microbial agent will help in preventing granulomas.
  • post exposure to unsuitable environment especially malls, road dust house dust soaps or even dirty hands also may contribute.
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Which of the following breast reconstruction flaps has the best outcome? TRAM flap, Muscle sparing free TRAM flap, DEIP free flap?
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The breast outcome is roughly the same. But the abominal outcome differs, the DIEP flap has the lowest morbidity on the rectus muscle and therefore the lowest rate of herniation...
If possible it's better to avoid the TRAM flap.
Between the free MS TRAM and the DIEP, the choice depend of the intramuscular route of the deep inferior epigastric vessels and the perforators size.
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I would like to do renal doppler ultrasonography after abdominal insufflation with carbon dioxide but the hyperechoic gas inside the abdominal cavity makes this procedure impracticle. I would like to share the experience of anyone who has successfuly conducted intraoperative renal ultrasonography during laparascopy to overcome this problem.
Dr.Davoud Kazemi
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Since the kidneys are retroperitoneal structures, air will stay anterior to them and they will be visible from a posterior approach without reverberation artefacts. You willl obviously not be able to use an anterior or lateral approach.
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Prune belly's babies survived with abdominal wall muscular weakness and disfigurement, and which age we can reconstruct their abdomen? and is it feasible to use mesh for strengthening of their muscles? and which type of mesh is suitable?  
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I would not be in a hurry to operate. Attention to bladder function is the first priority. I have one Prune Belly that never required surgery beyond my cinching up the trigone where it had been so weak and flexible that it would flip up and block the bladder neck. This boy is now in his fifties and with family and all.
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Children with previous repair of hypospadias by skin graft will continue to suffer at adulthood from hairy and short urethra and penile bending during erection.
What is the best technique to resolve such problem
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By hypospadias cripple, we mean a patient with insufficient suitable local tissue(prepuce, penile skin, urethral plate) for urethroplasty. The insufficiency stems from the complications of previous repairs.
In such cases, a two-staged Bracka repair using buccal mucosa graft gives very satisfactory results. However, the harvesting and grafting of an adequately large buccal mucosa patch needs skill and experience. One needs to observe the technique in the hands of someone skilled in performing it, before embarking upon doing it for the first time.
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I am currently working on my thesis and I am looking for more detailed articles about the surgical procedures used in hands and fingers re-plantations.
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Unfortunately the couplers are for veins only, ment to be used for reducing surgical time in larger vessels anastomoses and require an excess length of vessel which is not really available in most replants. There have been several research projects in the 80's trying to address the question you asked such as using lasers instead of sutures, doing continuous as opposed to interrupted sutures, sleeve anastomosis etc. I suggest you look up these studies
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An elderly woman who complained of progressive ulcero-nodular lesion eroding the lower palpebra and the palpebral conjunctiva.. Duration 5 years. No lymph nodes were palpable, hearing was good, no vertigo, no diabetes, mild hypertension was told.
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For a biopsy-proven basal cell carcinoma like this, Mohs excision would also be an option.  It can have the advantage that all of the margin can be evaluated, whereas a standard frozen section, or "wax" histology, will only bread slice the specimen and therefore its results will only be based upon a sample of the margin. 
The other advisable thing to do, of course would be a pre-operative CT scan to rule out intra-orbital involvement, which might require orbital exenteration.
  For reconstruction, personally, I would use a temporal skin flap for the outer lamella.  For the inner lamella and uspport, a mucoperiosteal graft from hard palate is also excellent.
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This issue is very controversially or undiscussed at all in the pertinent literature. On the one hand this kind of surgery may last for hours, and on the other hand this prophylaxis is not commonly used in children. What is your approach and practical experience ?
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Thank you, Dr. King. I share you opinion and clinical experience . The reason  to  ask this question  is  that  in  some standards for practicing orthopaedic surgery /i.e  . in my country/ the  requirement for pharmacolgic antithrombotic prophylaxis is imperatively required for major surgeries. No differentiation according to age, kind of operation,etc. is made. This  could  lead to litigation procedures in case of   rare PE or DVT after scoliosis .   Nevertheless, I do not use  anticoagulants for scoliosis surgery in adolescents.
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I do a research on the subject so if anyone can help me i would be grateful! 
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Apart from infrapatellar branch paresthesia sometimes a large hematoma can occur, post harvesting, in STG graft. 
For BTB I saw a technique of harvesting the outer portion of the tendon (less than 1/3, which is the case for the classic middle third BTB graft) that had less anterior pain than the classic BTB technique presented to us by prof. Georgoulis A
Quadriceps tendon has been reported with minimal donor site morbidity
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Tibial posterior transfer or nerve repair?
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Acute lesions not associated with knee luxation can be treated with excellent results in the long term. If there is loss of nerve length, I would recommend ipsilateral superficial peroneal nerve grafts to reconstruct the peroneal nerve at the time of injury. If the injury was due to knee luxation, I would recommend tibilais posterior (TP) transfer or even better a Riordan bridle transfer. For chronic lesions, tendon transfers work better than nerve repairs/neurolysis/exploration.