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Production Systems - Science topic

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Infectious diseases and predators are the two main challenges against the extensive system poultry production. How can we reduce their devastative effect?
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To reduce the impact of infectious diseases and predators on smallholder poultry production systems, a multifaceted approach is necessary. This includes implementing strict biosecurity measures to prevent disease introduction and spread, such as controlling farm access and practicing proper hygiene. Vaccination programs and disease monitoring are crucial for protecting poultry and detecting outbreaks early. Improving housing and infrastructure, such as constructing predator-proof facilities, helps mitigate predator threats. Diversifying farm activities through integrated farming systems provides alternative income sources and enhances resilience. Training and education on poultry management, vaccination, and hygiene are essential for farmers and communities. Access to veterinary services and extension support must be improved, along with providing financial support and risk management strategies to help farmers cope with losses. By implementing these strategies holistically, smallholder poultry farmers can safeguard their production systems and enhance their livelihoods.
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Compare the cost dynamics of organic production systems with conventional farming methods, considering inputs, labor, and overall operational expenses, and discuss the economic feasibility of organic agriculture.
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You have posted 10(!) questions one after one. For each question you are supposed to express your own opinion for discussion. Instead you posted very general questions.
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Does the environment have an effect on applying the success of some production systems over others?
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There are several modern production systems that are widely applied in factories around the world.
1. Lean Manufacturing: Lean manufacturing, also known as the Toyota Production System (TPS), focuses on reducing waste and optimizing production processes. It emphasizes continuous improvement, efficiency, and eliminating non-value-added activities. Techniques such as Just-in-Time (JIT) production, Kanban systems, and Kaizen events are commonly used in lean manufacturing.
2. Six Sigma: Six Sigma is a data-driven approach that aims to minimize defects and variation in manufacturing processes. It uses statistical analysis and quality management principles to improve process performance and reduce errors. The methodology typically involves defining, measuring, analyzing, improving, and controlling processes (DMAIC).
3. Agile Manufacturing: Agile manufacturing is a flexible and adaptive production approach that enables rapid response to changing customer demands. It emphasizes collaboration, quick decision-making, and efficient resource allocation. Agile manufacturing often involves modular production, cross-training of employees, and the use of advanced technologies to enhance responsiveness.
It's important to note that the selection and implementation of production systems depend on various factors such as the industry, product type, company size, and specific goals and requirements. Therefore, the "best" system can vary based on these factors, and it's crucial to assess and tailor the approach to the specific context and needs of each factory.
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Considering that nowadays we have mainly biomass, fossil fuel and nuclear energy as nature independent, what other independent energy sources would you consider for an energy grid?
Most likely in the future energy grids will have nature dependent, independent and buffers, but climate change impose uncertainty on generation of nature based.
Just a reference text:
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My dear friend Prof. Leandro Lima,
There will be no energy future for humanity in use of energy dependent on nature.
Humanity's only hope for maintaining consumption and development is with use of nuclear energy. In beginning based on nuclear fission until first sustainable reactors based on nuclear fusion are in full operation.
Without this, it will not be possible to dream of a promising future for humans on Earth.
Thanks for question,
Prof. Wiltgen
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Is the Journal of Production Systems and Manufacturing Science stopped publishing.
Can you comment on this query?
--- Prof. Santanu Das
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This journal is (used to be?) published by “ImperialOpen Publishing” and it seems that the whole website https://imperialopen.com/index.php/JPSMS/index is no longer functioning. Suspiciously little can be found about them. I think I found the owner https://www.zoominfo.com/p/Murat-Sarikaya/2645327288
Perhaps you can contact him to clarify the matter.
Best regards.
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I am analyzing a database of Amazonian farmers in chakra production systems.
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The meridian (chakra) is a chord expression form of life and self (Atman), involving the essence of life and self (Atman).
Preprint Chord Biology
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When the Total process formation calculations/product system calculations are done, some inventory results are found . But I do not understandRCTGFsfromenvironmentalan the meaning of these RCTGF for the environment perspective. And also the color differences, color code, and criteria?
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Dear Nafisa,
I think this may refer to better-known impact assessment methods in the phase of LCIA (Recipe, CML, Traci...) or normalization/weighting methods. By the way, I use Gabi, but that's how I feel. To my knowledge, OpenLCA uses 43 different LCIA methods. Best wishes, Viktoria
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I'm trying to find the carbon footprint results for a product system of a Power Transformer with:
  • Allocation method - Physical;
  • Impact assessment method - ReCiPe 2016 Midpoint (I);
  • Normalization and weighting set - World (2010) I;
  • Calculation type - Analysis.
I've already analysed all the results, the top 5 contributors, the impact results of the most affected impact category with the normalization and so on.
The openLCA version I'm working on is 1.11.0 and I've mixed up many free databases from Nexus.  Thank you very much for all the help. Best regards, Beatriz Teixeira
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Hello, I'm trying to calculate the results for a product system by selecting the following options:
  • Allocation method - None;
  • Impact assessment method - ReCiPe Midpoint (I) / ReCiPe 2016 Endpoint (I);
  • Calculation type - Quick results / Analysis;
  • Include cost calculation and Assess data quality.
Well, the results are always a list of zeros for every item in the LCI. I've already tried to do the following actions to solve the problem, however I didn't have any success:
  • Increased the maximal memory to 5000 MB;
  • Validated the database (it returned back with zero errors);
  • Opened the SQL editor and executed the query: select p.ref_id, p.name from tbl_processes p inner join tbl_exchanges e on p.id = e.f_owner where e.id = 7484497 (got the reference ID and the name of the process where the exchange occurred and searched for it, opened the process and didn't find any error message with more details or a warning popup).
The openLCA version I'm working on is 1.11.0. Thank you very much for all the help. Best regards, Beatriz Teixeira
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You might try deleting the current product system and make new flows, processes and product system. Seems like some mistake has been made in previous steps.
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I need the contacts of a company able to furnish or support the set up of a RUSITEC, a continuous cell rumen model. Could do you be able in supporting me? Or, at least, do you have a project of RUSITEC suitable for getting info on what it is necessary and which characteristics each component should have for its correct function (i.e. digesting chambers features, pipes diameters, pump technical characteristics, bags, etc) ? We already have a static rumen model (Ankom Daisy II) and an Ankom Gas Production System, but we want to evolve to a dinamic rumen model.
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Thanks for your question on Rusitec. Before you start any practical application on using Rumen simulation technology, you will need to clearly understand how it works and the dynamics involved. These include; the nutrients required in the media, maintenance of anaerobic and the operation of continuous batch culture. Some scientists have tried using large scale batch fermentation simulating the rumen environment in the production of single cell protein (SCP) (similar to microbial protein synthesis) as a substitute of conventional protein sources such as beef and lamb but have encountered a lot of challenges due to the fact that SCP has a high proportion of nucleic acid material which has to be digested and metabolized through the Xanthine, Hypoxanthine, uric acid and allantoin pathway. With high levels of uric acid as intermediate metabolite you the risk of precipitating gout which crystallizes in the human body to sharp crystals that cause unbearable pain in the body. In the meantime, here are some good references from extensive work/review that was done by Czerkawski .
Czerkawski, J.W. 1976. Chemical composition of microbial matter in the rumen. Journal of the Science of Food Agriculture, 27:621-632.
Czerkawski, J.W. 1986a. An Introduction to Rumen Studies, Pergamon Press, Sydney.
Czerkawski, J.W. 1986b. Degradation of solid feeds in the rumen: Spatial distribution of microbial activity and its consequences. In: Control of Digestion and Metabolism in Ruminants. L.P. Milligan, W.L. Grovum and A. Dobson (eds), Prentice-Hall, New York, USA. pp 158-172.
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Dear friends,
Dear friends, The published research results indicate that in the period 2021-2023, the cost of robots will reach the equilibrium point between the cost of human labor. In Poland, for the metal industry as well as for the semi-trailer production industry, in my opinion, this equilibrium point has been achieved. The pandemic only hastened reaching this point. There are two reasons: the lack of qualified specialists on the labor market and their high financial requirements, uncertainty due to the presence of employees and lower costs of purchasing and operating robotic production systems. I have a question - What is the situation in your countries? And what is the situation in individual industries? I encourage you to discuss and maybe joint research on this topic.
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Thank you for your response. In countries with low labor costs, the transformation process will be lagging behind in developed countries. In my country, we currently have a shortage not only of specialists, but of people to work in general. Covid is also a factor that influences the decision making to accelerate the transformation process. The fiscal policy of the state may also contribute to the situation that the cost of human labor exceeds the costs of robotic systems.
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I am making a research of mechatronics methods.
Can the six sigma be used for the design of mechatronic products or it is more oriented to the production systems?
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I'm afraid that there is some misunderstanding. There are two methodologies in Six Sigma: DFSS (Design for Six Sigma) for R&D projects (i.e. for new products/processes/technologies) and DMAIC (Define/Measure/Analyze/Improve/Control) for Engineering/Manufacturing/QC/Maintenance projects (i.e. for existing products/processes/technologies improvement).
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Disease free stock can be ensured by herd certification program. How can it be effectively implemented in a small holder production system?
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Repeat attached search and see the relevant entries. D. Booth
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For example, in a livestock production system, a sustainable GHG emission is until xx kg / ha / year.
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Bernardo Villalba there may not be the direct effects and might be many indirect effects on the livestock.....
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Productivity is a key aspect of economic growth. However, it is also important to choose what should be produced with the growing importance of taking into account the issue of ecology, care for the protection of the natural environment.
Do you agree with my opinion on this matter?
In view of the above, I am asking you the following question:
What is the significance of the development of production and the productivity in modern economies?
Please reply
I invite you to the discussion
Thank you very much
Best wishes
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… Clearly, increasing resource productivity is the way to resolve conflicts between future development and heavy resource burdens … The primary requirement for long‐term resource productivity development is increased income levels leading to higher resource productivity …Gan, Y., Zhang, T., Liang, S., Zhao, Z., & Li, N. (2013). How to deal with resource productivity: Relationships between socioeconomic factors and resource productivity. Journal of Industrial Ecology, 17(3), 440-451.
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Types like; Job Shop, Batch Production, Mass Production, Manual Line Production. and why?
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mass production, manual assembly line.
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Dear colleagues I want to write a review paper entitled" The potential use of biogas to meet electrical and thermal loads of building" please anyone wants distribution to inform me.to 1-Introduction 2-Evaluation the use of biogas in different parts of the world 3-Different usages of biogas 4-Recent progress in biogas production 5-Biogas fueled electrical power production systems 1-5-Micro gas turbine 2-5-Fuel cell 3-5-IC engine 6-Energy analysis of biogas fueled system 7-Exergy analysis of biogas fueled system 8-Economic analysis of biogas fueled system 9-Conclusion
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Good day! I am just studying the influence of various fuels on the operation of a gas turbine, it would be interesting to look at the composition of your biogas. You can jointly write an article in a magazine on the operation of a gas turbine on your train
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Hi
I wanted suggestions for already published research articles that can illustrate a complete Petroleum Production System which shows in detail a single diagram or list out multiple diagrams that can show the individual subsurface, well head, Christmas tree, pipeline and separators.
I am submitting an example illustration of a petroleum production and was hoping to find some more detailed ones.
Urgently waiting for suggestions.
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Depends on what you want to focus on, you may want to check the production text books, reservoir handbooks, and/or drilling books.
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Dear Colleagues,
A call for papers in an interesting special issue in Sustainability, "Environmental Sustainability Assessment of Crop-Livestock Production System"
This Special Issue welcomes papers covering the research associated with assessing and improving the environmental sustainability of crop-livestock production systems. The editor encourages the submission of original research and review papers that address the issues raised above. Please check the link for more details.
Dr. Davoud Heidari Guest Editor
#Sustainability #Environment #Life_cycle_assessment #Climate_change #Carbon_sequestration #Land_use #Foodsystems #Livestock #Agriculture #Mitigation_strategies #Special_Issue
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Thanks
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Companies were already in crisis before the pandemic. What will happen now that many workers are layoffs and sales have fallen?
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Many businesses operating in sectors where sales revenue has decreased due to the SARS-CoV-2 (Covid-19) coronavirus pandemic, will report either financial losses or small gains in 2020 reports. The scale of the losses will be correlated with many factors. Among others, with the following factors:
1. The scale of correlation between the development of the SARS-CoV-2 (Covid-19) coronavirus pandemic and the consumption of specific types of products and services by citizens.
2. Possibilities of developing sales for citizens of particular types of products and services via the Internet.
3. The scope of time and the level of rigors for the introduced lockdown of the economy, i.e. the legally required temporary closure of shopping centers, service plants, restaurants, hotels, cinemas, museums, city parks, schools, kindergartens, offices, etc.
4. Scale of citizens' compliance with state-established anti-pandemic and sanitary safety instruments (eg wearing face masks, home quarantine, restrictions on the movement of citizens in public places, etc.).
5. Information policy shaped by public institutions and central states dealing with the sphere of public safety and health, and information on the SARS-CoV-2 (Covid-19) coronavirus pandemic disseminated socially through citizens on social media portals.
6. The level of financial support for enterprises operating commercially by the state, from the state's public finance system, in order to maintain their continuity of operation during the pandemic, despite the real decline in the scale of economic activity (as part of the interventionist socio-economic policy and the so-called Anti-Crisis Shields).
7. The period of the SARS-CoV-2 (Covid-19) coronavirus pandemic, the scale of the pandemic development rate, the number of new coronavirus infections and deaths caused by severe Covid-19 disease. Best wishes,
Dariusz Prokopowicz
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I would like to design a solar hydrogen production system using PV solar cells to drive Alkaline Water Electrolyser, which requires studying the productivity of the water electrolyzer to estimate the amount of water needed.
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If you have the water quantity say 0ne grams, then you can first calculate the number of H2 molecules contained in the one gram mole of water= Avogadros number = one gram mole of hydrogen = 2.016 g/mol,
one gram mole of water= 18.01528 grams
So the ratio between H2 and water is
H2:water= 1/9
So, you can easily calculate either quantities if you have the other.
To produce one kg of H2 you need 9 kg of water.
To get one molecule of hydrogen you need two electronic charges 2q
The charge Q required to get one kilograms= 2qx no. of moles in one kilograms
= 2q x (1000/ 2.016 )x Avogadro number
with q= 1,6x10^-19 As and Avogadro number= 6.0221409e+23
Also every molecule needs a voltage to split it say Vsplit
The electrical energy required to produce one kilogram hydrogen= Q x Vsplit.
Vsplit minimum = 1.229 V
Practically one needs more than 1,229 V to split the water and the overvoltage required causes a conversion efficiency less than one.
Best wishes
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Greetings
With the dawn of the 21st century computer aided softwares & hardwares are used to optimize inustry operations.
Similarly we can see the use of Sensors in a Petroleum Production system with all the subsurface, and surface components being monitored and physical properties of the variables kept in check.
I was interested to know of research being done in this field where new challenges are being overcome & electronic sensors are being used to monitor and solve problems before they become a safety issue.
Hoping for a positive response.
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You can review about ABB sensors to be put in some parts of the machinery to learn about its condition and also there are a lo of kind of sensors that can be used to monitor the process condition and review the variables of the process these sensors are then monitorized by a SCADA system and if you want to go further can be presented in a DCS system in order to convert the continuous signals into discrete one and to get a total monitoring and tendences to predict the system behaivour taking decition before a failure ocurs
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What are the most important methods to quantify risk (failures, uncertainties...) for production systems ?
Especially for production systems, We look also on other fields ...
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Hello Oussama!
I advise you to use dynamic Bayesian networks. I think it is a very suitable method for dynamic systems.
Good luck
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With globalization and technological advances, we have seen that companies have been looking for new directions for production systems. So, what are the impacts of this system today?
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For example,
one could lessen the need of pepole contact to paper work by simply applying remote readers for 2D par codes and to get paper documents to work force tablets. Similarly, Near Field or RFID technologies could use to achieve the same.
Automated store and retrieval systems to lessen the need for workers to touch the containers the materials are stored into and so on:
And using of WMS to improve pandemic safety (this is one feature which is not too common, based on our previous literature findings on what one can find in WMS as functions and features):
Even sustainability issues are better in shape in WMS solutions at the moment:
For future work on considering on selecting the WMS solutions, pandemic safety should be one issue to look into too:
B.R.,
Ari
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Dear community,
here's some background concerning the question:
I am building my first LCA, and am finding it time-saving to avoid the LCI step almost entirely, and am using LCIA results from literature directly instead (plus one set of LCI data from GaBi).
In brief:
Fu: production of 1MJ (LHV) of fuel and use in an airplane operating at global average conditions.
First, I figured the amount and types of energy required for the production of the fuel. This included calculating the operational flows in fuel production stage (electricity and water).
Then I collected LCIA results from literature for all required foreground and background (aggregated) processes (all using the same impact assessment methodology). The LCAs delivering these results include the whole lifecycle of the processes. Examples of aggregated processes are the production of national grid electricity (this one I actually took from GaBi) and the manufacturing of the fuel production plant.
Finally it's just a matter of multiplying numbers together.
Am working in Excel.
Thoughts?
Thanks for any piece of advice!
******
EDIT
******
After receiving a few replies, I realized that I must be more specific. Here are some vital additions:
I do recognize that my approach is not rigorous.
However, all the LCIA results I´m using have been calculated using the same evaluation method (CML 2001, 2016) and all have the same geographical scope or validity and system boundary.
Additionally, the two hotspots of each indicator (in sum >95% TOT) are caused fuel production (indirectly emissions from the energy carriers) and use (direct emissions from fuel burn).
Knowing this, instead of using inventories from databases, I used LCIA results of LCA studies of those energy carriers valid in that precise region (Germany) and years (2015-2020 (min)). This way, I was even able to adjust the LCIA results for GHI (global horizontal irradiation) and wind speed conditions,
I figured this would deliver accurate results; potentially more so, than using databases.
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+1 Anju. "It is certainly not as simple as multiplying numbers."
The list could go on with 'technical uniqueness' - 'regional technical specificity', inconsistent time horizon, inconsistent allocation choices, etc.
But what is your goal ?
If I may Matteo, I invite you to read ILCD's handbook (more accessible than ISO, i.e. it's free to download and clearly specify the limits between ISO and ILCD). Even at this stage you may be able to understand inconsistencies within LCA's methodology. (Yeah, it's a deliberate profile photo). If you want to experience with modelling, OpenLCA may 'answer' this need (also free to download and use, but it comes without a database... again a lot of debates on data sources...)
As an engineer, I shared the same enthusiasm and was quickly disappointed when I realized I've been deceived about what we take for the 'most advance assessment methodology' during my thesis.
Hope it doesn't discourage you to try to understand the consequences of the products you design.
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To optimize a production system by planning ~1000 timesteps ahead I try to solve an optimization problem with around 20000 dimensions containing binary and continuous variables and several complex constraints.
I know the provided information is little, but can someone give a hint which approach would be suitable for such big problems? Would you recommend some metaheuristic or a commercial solver?
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One strategy is to define variables as time intervals - if the time interval is used for something, then a variable is set to one, and you then pay the fee - or whatever - for this use. By starting with long time intervals the production planning problem may be easy to solve, as the number of variables is small. You then use that solution as a starting point for a new problem, in which the time-steps are, say, 1/2 or even 1/10th of the previous time interval; your previous solution is feasible in the new problems, which will help the solver to quickly find an optimum to the problem. If you re-iterate like this until you have as small a time interval that you want, your optimum will be the solution of the last problem. (This is a very simple way of performing a discretization procedure.)
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Leagile means the integration a lean and agile manufacturing system. It means the assembler (manufacturer) should consider both the system of push and pull production system.
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My suggestion is to study the barriers,
to understand basis of the bigger picture in here :-)
B.R.,
Ari
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Hi. I am trying to synthesize RNA without G on the top of transcript in vitro.
But, by any commercial transcription kit, there is no way to make it. For example, using RiboMAX™ Large Scale RNA Production Systems from Promega, transcripts starts with G followed by double G.
Could you tell me how to synthesize such transcripts?
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The G´s in the 1st/2nd/3rd/ are preferred, but T7RNA-pol can also do its job without G´s in this position Although with a reduced yield (depending on the template/sequence). How long is your RNA? How much transcript do you need?
Sometimes it is cheaper to synthesize/order the RNA from a company.
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Note that the abbreviated words (optimized production technology)
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OPT can be used to schedule bottleneck capacity in an efficient way. This schedule is the master for the demand placed on other capacities. In a nutshell when we try to crash a project or when the stem is procrastinated a lot we go for OPT techniques. It’s most commonly used in Job shop productions.
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My research interest is in developing a computer based fault diagnostics system for sub-sea production systems if there aren't any existing already. And I am looking into areas such as gas hydrate problems, scale control, monitoring of sub-sea well pressure etc.
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Welcome,
I think so. Now everything can be. Technology knows no restrictions.
Regards
Joanna
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I am looking for the precise data-sets with minimal outputs or systems for analysis from manufacturing process based.
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I am researching the combination of ERP and Lean Manufacturing (TPS - Toyota Production System).
There is not so many literature and research in ERP-Lean combination post-implementation stage.
So far, the latest research that I found is from Powell.
  • Powell, D. (2013). ERP systems in lean production: new insights from a review of lean and ERP literature. International Journal of Operations & Production Management, 33(11/12), 1490-1510.
  • Powell, D., Alfnes, E., Strandhagen, J. O., & Dreyer, H. (2013). The concurrent application of lean production and ERP: Towards an ERP-based lean implementation process. Computers in Industry, 64(3), 324-335.
I really appreciate if anyone can share their knowledge in this field.
Thank you !
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Looking for scientists & labs who are building novel technologies to transform our food production systems to be as sustainable as possible? Alternative Proteins, Cellbased Agriculture, Plantbased Meats, GMOs etc.
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Dear Flavio,
That’s quite an ambitious and not that easy to answer question. However what comes up in my mind when it comes to food innovations (combined to agricultural innovations):
The so-called Food Valley in the Netherlands:
And France, this country has a strong history and reputation as well. See for example the following research centres:
INRA : National institute of Agronomic Research
CIRAD : Centre for International Cooperation in Agronomic Research for Development
IRSTEA : National Research Institute of Science and Technology for Environment and Agriculture
CNRS : French National Centre for Scientific Research (dedicated to fundamental research)
There are interesting examples of companies that focus on sustainability and have experience with (the acquisition of) start-up companies (like Soliance). See for example:
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Dear RGians,
I have to do a mini project work in 2 weeks.
Could you please help me to define a job shop scheduling problem possibly related to cloud or fog manufacturing environment?
I know basic python coding sufficient for algorithmic modeling.
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Dear Karun
My gross and personal definition of job scheduling, is:
The activity to organize people managing equipment, including type of equipment used, working either in line or in parallel for different products, with the same or different sequence, with different machine usage, different times and different volumes, in order to get the most efficient use of machinery which implies reduced idle time and rejects in each station, fastest speed of the production line, and good quality of final products
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I need to insert firm rubber hole plug in to sheet metal hole for sealing and covering purpose ( to seal for a long period of time).
Do you have any supportive idea for automatic or mechanical means of inserting firm rubber hole plugs in the sheet metal for mass production system? Please refer the attached picture.
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Hi Fitsum,
I'll have a look and see if I can find an alternative.
Regards
Martin
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Hello friends,
I'm currently using Ansys AQWA and I'm stuck up with position restraining of the platform by Dynamic Positioning.
I know about Passive control system i.e., using Mooring system for positioning the floaters.
But, I don't know about Active control system i.e., how to give Dynamic Positioning for floating platforms using Ansys AQWA.
If anyone knows, please do share your experience.
Yours faithfully
SYED AZEEM UDDIN
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Thanks for your response
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Task allocation problem is of critical importance in manufacturing industry, and determines the effectiveness and efficiency of advanced manufacturing systems. In order to be adaptable to the needs and future challenges that industry are facing, like rapid changes of demands and requirements, the cost of the entire production system have to be minimized. This performance start by optimizing the sequences of tasks and resource allocations through the system, and this can be handled by using computers optimization algorithms.
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This is essentially the same problem addressed in mu paper "Adaptive submodel selection in hybrid models" doi: 10.3389/fenvs.201500058
The paper describes a strategy for changing the mix of submodels used to represent a complex system in response to the efficiencies and needs of the current components.
This extends the work described in the paper "Increasing model efficiency by changing model representations", which is availabe on researchgate. A mathemarical structure is developed in the supplementary data which might help (also on RG).
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CDIO is based on a commonly shared premise that engineering graduates should be able to: Conceive – Design — Implement — Operate 
complex value-added engineering systems in a modern team-based engineering environment to create systems and products
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The best preparation is "Engaging". Graduate Engineering students have to be engaged in other to conceive. Innovative thinking can be harnessed when you put yourself in the environment that demands your effort or something new. New products or systems, be it sustaining or disruptive, solve one problem or the other, which can be detected by engaging. But engineers who only stay in classrooms and do not engage, find it difficult to think outside the box.
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I am looking for a fluorescent reporter that will be active when my cells are cycling, but off when my cells are quiescent/senescent.
Does anyone know of such a product or system?
As I understand it the FUCCI system does not provide this function, it simply delineates G1 from S/G2.
Thanks in advance! -
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Oliver Hickman what we use the mainly the BRDU incorporation as a reporter. alternatively you can use EDU.
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I am looking for a way to produce recombinant antibodies that is capable of adding short peptides to the antibody on the C or N terminal. Does anyone have a favorite system that won't break the bank? Thanks
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If you are looking for an easy, cheap and rapid system to make virtually any type of recombinant antibodies then its plant-based systems. The entry barriers in terms of skill and cost are super low. Here are some recent reviews / papers that you may find interesting.
Let me know if you are interested in this technology, i am happy to discuss ways for collaborations to get you started.
Cheers Markus
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TPS and Six Sigma
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Presentation detailing basic premise of both and comparisons.
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I am working with a NaCl+Gypum+H2O+Organic additives system. I have data of molar conductivity and viscosity. How to calculate walden product for this system. i tried to multiply molar conductivity and viscosity but it doesn't validated with some reference papers. So am i doing it right? what is best way to calculate walden product? Which equation is perfect for it?
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Thanks
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I particularly like to understand the energy use and environmental emissions related to mustard crop production system in India.
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There are a lot of studies around the globe on this particular topic, You may can google and find a lot of related stuff.
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What can be suggested to design farms so that mutualism between animals and their plant partners may increase efficacy to enhance the sustainability of food production systems?
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I would say that for herbivorous animals, the integration of pasture is a good way to reach a certain level of sustainability. If you develop grasslands in a good manner, you can store carbon (especially if the cattle effluent go directly in the soils), enhance biodiversity, potentially reduce GHG emissions. The matter is that it has to insure the cattle feeding resource also, to maintain a good level of productivity (in milk and meat). There exist many ways to develop grassland management skills and technics in order to reach a good level of productivity with pasture. Moreover, it can reduce the global costs for the breeder, compare to other aliments and breeding in buildings etc (effluent storage costs especially). By the way, pasture can be adopted partially, while keeping conventional sources of feeding also (silage forages, complementary aliments). Lots of things can be done
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who is interested in a Prima call (http://prima-med.org/calls-for-proposals/ ) Project about sustainable greenhouses (cold frames/monotunnels) production system (pests managment+impact on environment and human health, natural resources, irrigation, marketing...)
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Dear Asmaa Laarif
I am interested on.
Today we participated on a conference animated by a ministry member to expose how to subscribe in the PRIMA call. It seems that it is interesting.
Regards.
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Which tool can be used for life cycle assessment in agriculture production systems, if possible “Excel add in” would be highly appreciated?
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You can try OpenLCA which is available here http://www.openlca.org/
You can export the results to excel. OpenLCA also provide the databases (free and paid), but you can always use your own data.
Regards,
Dhani
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Governments in developing countries are being pressurized to feed their growing population. Thus, they have to do everything, including among other things apply inorganic fertilizers, cultivating marginal lands and converting forest areas for crop production. But, these types of interventions are not environmentally sustainable, and only gives temporary solution, for obvious reasons. So, given this paradox what do you suggest?
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This is a very interesting question because this problem was universal one so that developing countries take this issue in consideration and planned seriously for what to do in the following years to face it ,here is i am putting a pending file related with this issue:
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Why foam fracturing is less popular in enhanced geothermal system compared with shale gas/oil production systems? Since foams possess high apparent viscosity which is good for suspending proppants. In addition, foams also limit the water use, fracturing fluid leak-off, and lead to faster fracture clean-up due to gas expansion. Also, compared with shale gas/oil production system, foam fracturing enhanced geothermal system (EGS) would not induced clay swelling because the mineral of EGS are mainly crystalline rocks, say granite or diorite.
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The main disadvantage of using foam fluid for fracturing is its stability and controlled rheology over time beyond a particular temperature. Due to increase in temperature, the foam present in the HF fluid system undergoes expansion and finally bursts, leading to unstable system, in addition to those mentioned by Ma Zhaoyang . For this, application of foam fracturing fluid is mostly limited to low temperature and water sensitive reservoirs.
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Greetings,I'd like to know in your production equipments, how do you calculate the final stoppage / breakdown time?. Example: There are 5 machines in the production module with capacity and same product:
  • Machine A: 10 ton/h
  • Machine B: 8 ton/h
  • Machine C: 10 ton/h
  • Machine D: 5 ton/h
  • Machine E: 8 ton/h.
A specific day occurs a general stoppage, where all equipments have been stoped by this problem. The stoppage time of each equipment was:
  • Stop time machine A: 5.5 h
  • Stop time machine B: 3.4 h
  • Stop time machine C: 5.5 h
  • Stop time machine D: 8.2 h
  • Stop time machine E: 5.9 h.
There aren't production lines. What was the final stoppage time of production module?. Is the largest? (5.9 h). Is the smallest? (3.4 h). Is a weighted average/mean?.Thanks. PS. If someone knows bibliography about this, I'll appreciate the references.
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I hope these two articles help you, and look for johnson's rule as well.
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 New successful development of algae-based biofuels and co-products industry needs the optimum combination of technical innovations in systems.The processes,coupled with economic feasibility in the practical implementation and integrated scale-up for commercial production and marketing are the need of the hour.
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Nice
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Most of the times the term "Sustainability" is loosely used and there is no clear distinction between sustainability of the production system and the whole ecosystem. 
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Dear Mr Kaushal
Achieving sustainability is usually the effect of creating large or small ecosystems that provide appropriate support for sustainable development. There is however no established definitions of "eco-systems", neither as natural systems nor as technological or business-oriented systems. Policy-makers and researchers are frequently using the term for many contexts, which may be confusing. WIth regards to sustainability definitions the UN goals from the Paris agreement give a better guidance than Brundtland's three perspectives of sustainability.
In the 5GEM project, radically increased connectivity provides sensor-equipped machines as well as iPhone-equipped machine operators with 5G (i.e. close to real-time = a few milliseconds latency) communication capabilities. The technological advances enable smarter work-place design as well as radically improved control mechanisms for machines. This allows for measurable increases in social as well as environmental sustainability.
During the last 7 years, Chalmers University of Technology has run a cross-disciplinary initiative for sustainable production which involves more than 250 Chalmers researchers and PhD students. Feel free to explore our website for inspiration on sustainable production/manufacturing. We always try to avoid loose sustainability definitions, but the UN goals really provide great challenges for the whole manufacturing research and industry community. Please feel free to interact with us regarding the 5GEM project or other ideas.
Kind regards,
Professor Johan Stahre, 5GEM project coordinator and former codirector of Chalmers Production Area of Advance
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Despite the process being linear and simple, lean implementation would optimally require the implementation of the Final Assembly Schedule for the downstream activities that then pull the production system. But how can the process pull products that are one of a kind such as printed photo books? Is there any successful implementation on record?
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 First define your constraint within the process. Once you have your constraint identified then define the buffer that you want to maintain at or just before the constraint. That buffer will set the drum beat for the release of new jobs to the line. As the buffer goes down it should signal a release.
 It sounds like you are working in a high mix situation. Managing your bottleneck still will yield the best throughput results. 
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Under the traditional production systems, smallholders are getting more irrelevant given the changing market structure as consumer preferences continues to evolve. The situation is expected to  worse in the advent of climate change impacts. Therefore, establishing framework for sustaining and enhancing smallholder producers participation in the supply chain holds potential to address the escalating poverty levels among the rural population as well as enhancing food availability among non-farming households.
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Contract farming is better than collective farming for smallholder farmers. It address the price volatility problem as collective action mostly ex-post issues.
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The single-supplier multi-retailer joint replenishment game can be stated as follows: a number of independent retail facilities know demands of a single product. They order goods from the same supplier. All shipment from supplier's warehouse to retailers are direct. Both of transportation costs and linear inventory holding costs are supported by the retailers.
A group of retailers  would like to form and alliance and replenish their inventory jointly to save on delivery costs. Now, the questions are:
1. Which are the alliances that are more likely to be formed?
2. How should the retailers fairly apportion their achieved savings?
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Dear Anna,
Achieving consistent and acceptable cost structures to satisfy all retailers is a great problem to the alliance. More so, satisfying all demands without backlogging poses a great challenge; especially for items with demand uncertainty.
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I want to use the traditional Cobb-Douglas production function in order to measure the productivity of specific agricultural production systems. In this framework, I am going to use SPSS software to "run" the analysis. Has anyone used this production function in SPSS? Please provide any sources (papers, books, etc).
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Thank you José Vasconcelos-Raposo for your answer. Can you provide any sources, especially in the framework of the SPSS and Cobb-Douglas function?
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Excessive use of trace minerals (i.e. zinc and copper) causes environmental pollution. However, the story does not have its end right there. Similarly to genes related to resistance to antibiotics, it has been observed that bacteria also develop resistance/tolerance to such minerals.
As a consequence, we have to (not must) reduce their use. It is not easy at all, of course.
Thinking about solutions, why not to include an specific line of incentives within that existing related to environmentally-friendly production systems? This could be a measure to reward/encourage the implementation of more sustainable practices. In case that environmental protection is still not enough, such increasing resistance/tolerance to minerals and their consequences for human health should justify the existence of specific incentives; at least during the first years of transition, while science and technicians get used to manage under new rules.
What are your views?
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A.J. I agree with you. I think agricultural subsidies or incentives will help. Even though the EU has reduced Cu and Zn levels, i don't think they are the only trace elements. Therefore if your idea is taken up, it will really do some good; provided there's no interference from the people who started the project in the first place.
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I am a newcomer here...  I am interested in the decoration and the patterns on the traditional Mongolian Furniture. I wonder if I could use the Shape Grammar to make clear the decoration culture on Mongolian Furniture. So I could find a way to design the new Mongolian style furniture. 
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Hope attached one is useful for you. Regards
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Can identify the intensity of agricultural production systems and levels of fertilization, mechanization and other applied through remote sensing?
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Hi Armando,
Questions like yours get asked quite often on RG, and responses quickly go to specific technical suggestion of data types and algorithms. It is worthwhile first to think a bit more about what you are after, and clearly define your objectives. For that you first need to be clear on what land use is, including how it differs from land cover. Remote sensing is natively suited to determine land cover (water, soil, grass, etc.). Going from there to land use is already a big step (e.g., is a forest a natural forest or a production forest, or is a patch of water a natural pond or similar, or some artificial water body with a specific purpose). Hence you need some form of contextual analysis to go from cover to use, such as object-based image analysis (OBIA), though there are also many other techniques.
Now, your questions even goes beyond the above. What is “level of intensity”, specifically? Well, first of all, this will differ for different land use types. It could mean that if you have an agricultural land some form of crop rotation can be used – e.g., plant a different crop every year for 3 years, then leave it fallow for one year. This could be seen as intense use, and if you had 4 yearly satellite images taken at the right time in the phonological cycle (not in winter, for example), you could detect this. If, for example, you found that the field is not left fallow in the 4th year, maybe you could say that the use is too intense. However, if you had a system where 2 crops are planted on a field per year, you would already have to get more images to detect that dual use per year. Point is that you need a clear concept and definition of the types of land use in question, and what defines “intense” use. Only then can you determine the type of imagery you need (do you need RGB, or also NIR, what spatial resolution, etc.).
In sum, establish a clear concept and definition first!
Good luck, Norman
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The potential for assistive technology in learning classrooms for students with disabilities is great. Its benefits include enhancing academic achievement in written expression, reading, mathematics, and spelling; improving organization; and fostering social acceptance.
As defined by the Individuals with Disabilities Education Act Amendments of 1997 (IDEA), an assistive technology device is "any piece of equipment, or product system. . . that is used to increase, maintain, or improve functional capabilities of individuals with disabilities" [Part A, Sec. 602(1)].
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Software show be able to generate appropriate model with inputs provided.
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Dear Colleague.
At first, I suggest that you evaluate all the variables you have in such called dynamic system. Have you got the cause-effect process within each one those? What effect do you want to manage? Are there people's actions involved on such variables? How often do you want to evaluate them? May be you, by yourself, can model your process.
So, what are the effects that must managed? And what are de variables related to these effects?
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Information sharing and exchange between OEMs and suppliers is a new approach to enable responsiveness.
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Besides smooth flow of information, the process includes smooth flow of materials from suppliers, smooth production and smooth delivery to end customers.
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How can 4D print be used in the lean production/lean manufacturing?
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4D Printing can be used in lean manufacturing since materials should be programmed to adapt in respond to environment situations. The rest should not be much different from 3D Printing 
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For my research problem, I have to give external workload in cloudsim. I have found some from http://www.cs.huji.ac.il/labs/parallel/workload/logs.html but these workload are too much larger.
Cloudsim was failing to simulate it. I have increased the JVM heap size so now it is working. Can anyone suggest me any website allowing free download of small sized workload of various categories such as CPU intensive, I/O intensive and network intensive?
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Thank You Mr Hs Guruprasad.. Can you give me more details? How to do that ? Specially for creating different types of workload such as CPU intensive, I/O intensive and N/W intensive workloads.
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This question is about naming.
I am struggling to find out whether a name exists within the field of operations management research in order to address such an "approach" explained as follows:
  • you have a production system (even a simple equipment) as your base case (let's call it BC);
  • you plan to invest in a new configuration of your production system, or simply to change its operations --> you model one or more possible design alternatives (let's call them C1, C2, etc)
  • you define the performance indicators you will use to compare BC, C1, C2 (can be economic, environmental ones)
  • you model how these systems may work, calculate the indicators and compare the alternatives. 
Any references, if well-connected to this topic, are most welcome.
Thank you in advance
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You can study  the PROMETHEE for   multi-criteria decision making . It will help you.
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Three specifications:
  • the impact assessment occurs within the design stage of the system
  • for "production system" I mean not only whichever manufacturing system, but also systems for end-of-life processes (e.g. disassembly, recycling)
  • the impact is with respect to sustainability, hence, economy, environment and society.
Many thanks.
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Hi Ilaria,
Kassu already send you an extended lists of possible sources.
From a Quality point of view, I do like very much the APQP Automotive Industry Methodology: QFD, Product FMEA, Process FMEA; MSA, Process Capability Study/SPC study, Control Plan. It should assure that your process in under statistical control and has a good process capability to deliver quality product to the customers (a bit heavy methodology for many organizations, but …).
Environmental speaking, there is an ISO standard for this purpose: ISO 14044, Environmental management — Life cycle assessment — Requirements and guidelines. However, in my view, many times you do not need to do a full LCA, a simple consideration of the life cycle stages which can be controlled or influenced by the organization might be sufficient. For this purpose the organization may obtain this information directly or seek it from the supplier of the products and services. Information already developed for regulatory or other purposes may be used in this process. Typical stages of a product life cycle can include, for example, extraction of raw materials, design, production, transportation, use, and end-of-life treatment. The life cycle stages that are applicable will vary depending on the activity, product or service.
SA8000, available for download at Social Accountability International web site (http://www.sa-intl.org/) might be of interesting to you for social impact and they have good lines on how to interpret and apply it.
And if you want to make it really summarized, why not use CANVAS strategic model (1 page, available at http://www.canvaslms.eu/).
I used a model to research the influence of Sustainability/CSR programs in Organizational success (mediated by stakeholders satisfaction) for my PhD Thesis (framed on Stakeholder Theory and RBV) but looking back, it is a very heavy and quantitative demanding approach and is written in … Portuguese.
I wish you the Best.
Luis Fonseca
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I am interested in executing a Data Envelopment Analysis, and my target is to compare the technical efficiency of cow-calf systems (4 different countries). The sample should be around 15 farms per study area. I am interested in analyzing the technical efficiency of each study area individually and then comparing the efficiency scores. Due to the fact that socio-economic conditions are different, and price-cost relationships rise doubt in the use of prices of resources, I intend to use physical indicators in the model. Prior to applying a survey I am interested in:
1. Is it possible to compare the efficiency scores of different countries (observing the same system) and how?
2. Which criteria should be applied to distinguish the sample farms? Size in LU?
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Make a model for each  country and compare fit of statistics.
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Production systems; beef cattle.
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Hi Guilherme, in my opinion such importance in the study of ANN is related to the cost of the variable prediction. As Ali told, nowadays there are a lot of applications of ANN, but results have to be proven (at least, models are coming rapidly and trying to predict interesting behaviors).  Perhaps some research on the area can help you! Cheers, M
Aim: to predict the success rate of in-vitro fertilization (IVF) using Artificial Neural Network (ANN).
Application: to assess the possible success rate of the treatment which could help the gynecologist to suggest the infertility patients who undergo fertility treatment for baby.
Aim: to investigate the potential of two types of intelligent learning methods, artificial neural networks and neuro-fuzzy systems.
Application: to estimate breeding values (EBV) of Iranian dairy cattle.
Aim: to assess the protective effects of Ginkgo biloba's (GB) extract against chemotherapeutic-induced reproductive toxicity using Neural Network Clustering (NNC) on two types of data: biochemical & fertility indicators and Texture Analysis (TA) parameters.
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Do you think that modern food retailers can contribute to the organization of production systems in developing countries and a positive change in their production practices and productivity?
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Strongly i agree.
Growing corporate power in agriculture has led to steadily rising prices for staples like meat, milk and eggs, while the farmer’s share of the consumer grocery dollar has fallen. F
As more consumers consider the environmental, health and social consequences of industrial food production, demand for sustainably raised foods is growing. According to the USDA, farmers are dedicating more and more land to organic production G in response to consumer demand, with total organic acreage increasing at a rate of 15 percent annually. F
Farmers' markets, food cooperatives, and community supported agriculture (CSA G) programs continue to grow in popularity, making local, sustainably produced food more available. These programs offer consumers the opportunity to put their dollars directly into farmers' pockets, cutting out cooperate middlemen and strengthening a regional food system. 
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Many researchers argue that EDI (i.e. Electronic Data Interchange) technology does not provide flexibility, arguing that EDI is out of date technology. To what extent is this claim valid? To which industry sector to this valid? What is the alternative?
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Intranet technology is already adopted by most of the system suppliers. The new trend is to use Enterprise Content Management Systems for sharing not only of documents but sharing of real-time dynamic production data. A good approach is to extend the existing functionality of existing CMS (like SharePoint) with additional Manufacturing Operations Management (MOM) functionality, such as ISA 95 objects, OPC, BAPI, etc.  
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In a production system, such as crop production, different combination of agricultural inputs are used. The optimum application of these inputs can help to save energy and reach sustainability. Several methods have been used to reach better combination of these input materials. i.e. optimization techniques can be widely applied to find the the best combination of inputs especially when multi-objective approach are used. But how reliable are these results, considering that other factors can affect the results, i.e. the weather condition, interaction between some inputs (different types of fertilizers in soil), unpredicted condition and etc.
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Any multi-objective problem consists of objective space, decision space and given parameters. If parameters are fixed, you can find optimal solutions. For any change of parameters, optimal solutions are changing, too. Therefore, some adaptive control of system behaviour, depending on parameters change, can be employed if the system should follow parameters change optimally.
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I am writing a paper on techniques to determine modules of products. I was reading the work of Huang and Kusiak 'modularity in design of products and systems' and I was wondering how exactly you go from the conceptual design to the detailed design. They give an illustration in section V. B. but I'.m not quite sure what they mean. So what do you do once you determined modules in the conceptual phase and go to the detailed design phase?
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See also work of the same authors in CIRP and ICAD conference in Korea