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Tax cuts to the rich is the prefer idea on how to promote and expand economic growth in supply side economics despite knowing it does not work as expected. Yet, this policy is usually the first choice in supply side run democracies like in the USA or now the UK when supply side promoters are in power.
Any policy that worsens inequality should be expected in practice to negatively affect economic growth as under extreme inequality or worsening inequality the traditional trickle down should be expected to be mute or not to work as intended. And this raises the question, tax cuts to the rich and the embudo effect, is that why the trickled down effect does not work as intended?
What do you think?
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Where is the evidence that supply side economics does not work with respect to inequality? In the private sector, supply side economics has been shown to work every time it is invoked. When Government becomes involved, there is economic distortion with respect to the types of programs instituted, which undermines inequality outcomes. Economies need innovators to "prime the pump" of real wealth spreading, where jobs are created, which decreases somewhat, so-called class inequality. Inequality, in the socialist sense, presumes the rich not reinvesting profits to grow business further. When there is "crony" capitalism, collusion between politicians and corporations occurs, which undermines innovation and initiative. We've seen this in the USA, where small businesses were crushed by government policies during the pandemic, but large companies were largely untouched. Undermining legitimate competition is a tool of crony capitalism, and is presently part of the so-called globalist "Great Reset".
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Have you bought groceries or food lately? Have you noticed that the cost of items that form part of the production cost of the product or service you are buying, like plastic bags or food containers that once were free pollution, are now being charge extra to consumers when buying passing to them the apparent environmental responsibility of dealing with them, but the extra money now you are required to pay for the same plastic bags/containers goes directly to the company profits, not to any private nor government nor even to the same company recycling program as perhaps there is none. And governments seem to be okay with this new practice which is now spreading from major corporations to small businesses leaving consumers with no protection.
In a sense, dwarf green markets provide a cover for companies to pass their cost of production plus the “green grab” to consumers usually without having to disclose in advertising what they are doing so, a kind of deceiving as if those items cost more to companies now increasing their production costs that way, then they should increase the prices of their products or services instead, giving that way the option to consumers to buy at a higher price or not.
So consumers pay more, but their extra pay has not clear environmental benefits from consuming at a higher price, which raises the question, under dwarf green markets are consumers currently being scammed by the business community?
What do you think? Please detail your own view.
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Dear Lucio,
Yes, under dwarfing green markets, consumers are now often misled and/or deceived. For example, food sold in supermarkets as being made from the raw materials of crops grown in fields under a sustainable, pro-environmental organic farming formula and unfortunately this is not always true. This is due to the low level of public awareness of farming according to the formula of sustainable, pro-environmental organic farming and to imperfect quality control systems and ecological issues. Besides, why is it that the costs of using plastic in packaging are still being passed on to consumers and not fully borne by producers. The costs of using plastics in packaging are not only production costs, but also costs resulting from environmental pollution by microplastic particles, costs for the treatment of diseases resulting from environmental pollution, costs related to waste sorting and recycling. Another issue is the increasing practice of companies, businesses, banks and other economic operators to portray themselves in advertising campaigns as economic operators who operate in accordance with business ethics, pro-environmental and pro-climate corporate responsibility, pursue sustainable development goals, applying the principles of the green closed-circuit economy, when this is often not entirely true. In this way, consumers operating in dwarfed pseudo-green markets are misled. Consumers buy products and services on the assumption that they are thus part of a growing sustainable, green, emission-free, pro-environmental closed-loop economy. They purchase products and services offered by economic operators who advertise themselves as companies, firms, banks, etc. that have sustainability, green economy, climate change, etc. as part of their mission. However, the data describing the overall activities of these economic operators show that these issues of sustainability, green economy, pro-climate transition often represent only a small part of their activities and not the whole. Consumers do not have the time or opportunity to verify this. It is therefore necessary to strengthen the control systems carried out by the state's public institutions. Another issue is the pro-climate transformation of the energy sector. Due to the current energy crisis, instead of accelerating the development of renewable and emission-free energy sources, it is the state that is taking a step backwards and developing subsidy systems for rising fossil fuel prices, thus again supporting the development of dirty, emission-intensive energy based on burning fossil fuels. In addition, over the last few years there has been an anti-climate and anti-environmental policy of deliberately slowing down, restricting or blocking the development of renewable and emission-free energy sources. This is the case, for example, in the country where I operate. In view of the above, unfortunately, green markets are still imperfect, overrated and lacking systemic state control.
Warm regards,
Dariusz Prokopowicz
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More exactly, do you know of a case where there are repeated, continuous data, sample surveys, perhaps monthly, and an occasional census survey on the same data items, perhaps annually, likely used to produce Official Statistics?   These would likely be establishment surveys, perhaps of volumes of products produced by those establishments. 
I have applied a method which is useful under such circumstances, and I would like to know of other places where this method might also be applied.   Thank you. 
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Steve MacFeely -
Thank you. I found the attached using your response. It has just two questions: value of business off and on the internet, and appears to be for UK businesses for a month (actually, five weeks in this case). If it makes sense that one would want to know the total across all UK businesses, and that one has a past year census and a current month sample, then one could use the methodology found in my paper. But I did not see an annual form to see if it had the same data items. (I suppose this may be found somewhere in https://ec.europa.eu/eurostat/web/structural-business-statistics.)
If the monthly is also a census, it could then at least be used as a hypothetical case, as with the Toxic Release Inventory example I used. One could collect some key results for large businesses and have an early "prediction" (estimate for the random variable) before the ma and pa businesses all finish replying to the current survey.
Thank you - Jim.
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What do you think are the key factors that could trigger a food crisis in your country in the next quarters and/or years?
Due to many different factors, a food crisis can develop in many countries. The international supply and supply logistics chains that were interrupted during the SARS-CoV-2 (Covid-19) coronavirus pandemic have not been fully rebuilt. Rising fuel prices are driving up the cost of transporting food products to shops. The decline in fertiliser production is also driving up the cost of producing crops. In addition, the war in Ukraine has resulted in a decline in cereal supplies to many countries. The lack of electricity has caused a decline in the production of nitrogenous fertilisers. This then caused a decrease in the production of CO2, which benefits producers of many types of food products. Many food product factories are raising the prices of their products due to increases in raw material, energy and fuel prices. Many production facilities are reducing the scale of production. There may be job cuts. Consumption is falling due to high inflation. If a downturn in the economy occurs in the next quarters, many companies may go out of business and unemployment will rise. In addition, periods of increasingly severe drought, more and more hot days and less and less rain and more and more frequent fires in many parts of the world are causing a significant drop in crop production in agriculture. On the other hand, further food crises may arise in the future in the long term, which will be the result of a global climate crisis developing on a multi-year scale.
In view of the above, I address the following question to the esteemed community of researchers and scientists:
What do you think are the key factors that could trigger a food crisis in your country in the next quarters and/or years?
What should be done to reduce the scale of development of the food crisis?
What is your opinion on the subject?
What do you think about this topic?
Please reply,
I invite you all to discuss,
Thank you very much,
Regards,
Dariusz Prokopowicz
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Dear Dariusz
I dare to assert that all epigenetic factors may initiate a food crisis (Social interaction, war, disease, financial, created deficiencies etc.) More important is to have strategies to contain an emerging problem so that it will not spread globally. To avoid that we formed the UNO. In the post war era we also created the global market. Unfortunately, this is an economic concept that is based on competition and the winner in competition are those with with power. Now we are witnessing the global economy is dividing and consolidating in blocks. Unfortunately, the blocksformation is permananentl restructured and driven by a few war mongers. For them power is more important than food for the global citizen.
Many people are afraid and believe that we have too many people on the globe. For them war is the preferred mode to assure access to food. They cant imagine that with innovation and new circulatory technologies it is possible to multiply food supply. Food shortage is always a distribution problem. There are many actors around that increase value through shortage. The alternative is entrepreneurial collaboration with advanced technologies to assure a very large diversity of healthy food, enhanced with free global trade via internet. Science has failed to convince taxpayer that with sustainable technologies we will always have enough food for everybody.
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Population dynamics is usually linked to system stability. For example, over population is linked to system unsustainability, and possible system collapse through overshooting behavior like ecological overshoot. Population dynamics is rarely linked to market pricing structures as markets are usually presented as supply and demand interactions consistent with their price structures. But market price structures can be seen as linked to the nature of the population they serve. Hence, population dynamics appears to be the connection between market price structure and system stability.
And this raises the question, Is population dynamics the link between market pricing and system stability? I think yes, what do you think?
Please, feel free to share your comments, Yes and why you think is Yes or No, and why you think is No.
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Dariusz, the way you try to share your material is not helpful for sharing ideas ...you say Yes, In will leave it there.
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How can rising inflation be effectively contained?
On the one hand, the various instruments of monetary policy , fiscal policy, ... that have previously been used to stop the rise of inflation are known. On the other hand, for some reason the various anti-inflationary measures applied in 2021 and 2022 are working to a very limited extent. Therefore, can the rise in inflation get out of hand? Could the rise in inflation, the increase in fuel and energy prices and the projected downturn in the economy lead to the emergence of an economic crisis in the following quarters? Could there be an economic recession and stagflation in 2023?
What do you think on this subject?
Please reply,
I invite you all to discuss,
Thank you very much,
Greetings,
Dariusz
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Perhaps a novel way is to make stock exchange investment more alluring which will reduce consumption leading to a drop in inflation. This is what happened in Greece during the end of the 90's when everybody invested in stocks and inflation dragged down by a reduction in consumption pushed inflation from double digits to a level where it was possible for Greece to join the Eurozone.
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Hey there,
i am writing my bachelor thesis at the moment about an LCA for wishbones. Unfortunately i can not find that much literature about the energy amount that is needed for following production processes:
- Aluminium Forging
- Hot Rolling (Steel)
- Steel Stamping
- Metal bending (Steel)
Hopefully someone could help me & send me his assessment about the energy that is needed for those processes (Baste Case: kWh / kg)
Thanks a lot!
Hannes
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Have you looked in Environmental Product Declarations? These are summary LCA documents mainly used by the construction industry. For example look at the website Environdec.
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I am currently conducting a study on the effects of adopting IoT and Big data technologies in a manufacturing facility. I'm trying to get hold of data that would concern the change in the capacity of the plant, the maintenance costs, and OEE. I am aware that there is previous case studies on the matter but I am trying to quantify the change using real data. Does anybody know where I can find production data of a manufacturing facility I can use?
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You would have to get in touch with some of the companies and see if you can request the data. I would imagine not many will be fore coming. However, if you sign a NDA and you arent going to publicise were the data has come from then they may be willing to provide you with the data. Does your University have any collaborations or partnerships with any manufacturing companies. If they have it may be easier for you to go down that route.
Best Regards
Martin
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In the near future some non-biodegradable materials will be replaced in production processes for other, biodegradable. For example, plastics in the European Union until 2021 are to be withdrawn from packaging and replaced with other biodegradable materials such as paper or packaging produced from food, eg from cereals. But this is just the beginning of the revolution in the development of pro-ecological material innovations. This is only the first step towards the withdrawal of plastic as one of the main factors of littering the natural environment.
Do you know other types of examples already implemented or planned to implement projects to replace plastics with biodegradable materials?
Which biodegradable materials will be replaced in the future by plastic that is being phased out of production?
Please, answer, comments. I invite you to the discussion.
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Very interesting topic. In my opinion, bioplastic may a more realistic / alternative solution since the actual research works are focusing on the possibility to elaborate bioplastic from renewable resources, which will have the characteristics to be biodegradable / recyclable.
Here's in attached a recent article treating the economical potential of bioplastic.
Best wishes,
Sabri
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CO2 is used as raw material for chemical syntheses. It paves the opportunity to mitigate the greenhouse gas (GHG) emissions. However, it is not mathematically or logically proved yet that carbon capture benefits the environment in terms of resource efficiency. In my opinion, I believe that the life cycle assesment (LCA) would be the most suitable tool to quantify the resource-based benefits due to carbon based methane (CH4) production and to prove the resource efficacy of carbon capture.
I would like the researchers who read this discussion to provide their own ideas on whether LCA is the most suitable tool to identify the carbon capture resource efficacy or are there any methods better than LCA that can be applied on CO2 based methane production.
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"Life cycle assesment (LCA)" could be jointly addressed with the "circular economy (CE)" and the "ecosystem service valuation (ESV)", as an integrated tool to "quantify the resource-based benefits due to carbon based methane (CH4) production". Besides, this integrated approach can better control the excessive use of material, lowering the energy needs for new products, saving natural sources from overexploitation and environmental degradation, managing labour's capital, and proving the resource efficacy of carbon capture.
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We hear about environmental problems or social problems or socio-environmental problems associated with business as usual, problems being exacerbated currently by over population pressures and overshooting pressures. Hence, all those problems and pressures seem to be associated with non-optimal market conditions in practice, but conditions that are assumed to be optimal in theory, hinting towards a practice-theory inconsistency problem.
And this raises the question, Is the destruction of full optimality at the heart of system unsustainability problems? I think yes, what do you think?
Note: Moving away from full optimality thinking is what is meant here when saying "the destruction of full optimality".
Please, feel free to express your own views on the question, Yes, and why you think so? No, and why you think so?
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Dear Lucio
What I tried to say is that, in my view it is characteristic to the sustainability-related discussion in economics to disregard the factor time when talking about pricing and equillibrium.
Regards
Michael
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Are the targeted aging of products used by producers, deterioration of product quality, shortening the life cycle of products is a solution to the problem of overproduction, ie excess supply versus demand or rather overproduction of fast-wearing products and accelerated growth of waste and debris, increase in non-renewable raw materials consumption, increasing costs of reclamation, environmental protection, health protection and other additional social costs?
Please reply
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From the beginning of the industrial revolution and the description of the functioning of enterprises in the conditions of market structures, in the trend of classical economics, three types of production factors dominated in the production processes defined by three slogans: land, labor, capital.
However, successively with the development of industry and technological progress in the 20th century, other categories of production factors, typical for economies largely based on information, are added to these classic factors of production.
These factors of production, whose role in many industries has been growing since the 1960s include: knowledge, information, technology and innovation.
In view of the above, the current question is: In what branches of industry such production factors as knowledge, information, technology and innovation are currently or become the most important?
Please, answer, comments. I invite you to the discussion.
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Dear Alhaji Ahmadu Ibrahim,
Yes, intellectual capital is one of the most important success factors for many business entities and projects implemented in various spheres of human activity.
Thank you very much,
Best wishes,
Dariusz Prokopowicz
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Demographers estimate that by 2050, the number of people on Earth will reach 10 billion. With such a number of people, the agricultural economy, logistics of food supplies and people's eating habits will have to change. It is likely that economics will force these processes, which will result in the transition of the majority of humanity to nutrition mainly based on vegetable and vegetarian diets. Meat production is many times more expensive than the production of cereals, fruits and vegetables. In addition, according to scientific research and the theory of futurologists, the production of traditional meat, e.g. pork and beef, may be replaced by the production of protein from insect breeding. Research shows that there are more proteins in the bodies of insects than in traditional meat dishes. In addition, the logistics of food supplies, agri-food products will have to improve. Systems for matching agricultural and reptile production to the current needs of the industry and the nutritional needs of people will be improved so as to reduce the scale of food wastage. The biggest threat to the implementation of this plan may be unexpected atmospheric phenomena, natural disasters, droughts, hurricanes, tropical heat in the areas in which agricultural crops have been cultivated so far. In addition, industrial exploitation of arable land and climate change causes soil depletion and the disintegration of areas suitable for agricultural production. Therefore, it will be necessary to continue the technological progress in the production of crops, in biotechnology, in the creation of new plant varieties resistant to pests and adverse climatic changes.
Please, answer, comments. I invite you to the discussion.
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With rising income food consumption patterns also change. Calorie intakes of poor and rich people are surprisingly similar, but rich people consume more protein. This adds about a further 1 percent growth to food demand which means that the world will need to produce approximately two percent more food annually if today’s poor become rich. The growth of supply needed for the future about 2 percent annually has to come mainly from available farmland to avoid an overly negative impact on fragile ecosystems. This requires finance, investments, innovation, and knowledge to improve the yields at existing farmlands. The yield gap between what’s needed and what’s being produced is still very high. On the other hand, reducing food waste can have a significant impact on the availability of food. Reducing food waste can improve the efficiency of food value chains and help to distribute food more evenly to those in need.
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What kind of scientific research dominate in the field of Smart production?
Please, provide your suggestions for a question, problem or research thesis in the issues: Smart production.
Please reply.
I invite you to the discussion
Thank you very much
Best wishes
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Dear Dr. Dariuscz Prokopowicz,
I consider that the type of scientific research that dominates in the field of "intelligent production" revolves around theoretical discussions about the existence of "intelligent territories", generating in turn a concept that has been developed recently, taking as bases the notions of:
a) "Knowledge Society"
b) "Knowledge Economy"
c) "Sustainable Development"
d) "Social Inclusion".
These are new types of territorial spaces in which we interact for the sake of a new advance in the Economy and thinking about the New Social Structures that are being generated after Covid-19 with new behaviors of Human Beings.
My respects.
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To support the debate I enclosed the slides of IEOM South America 2021 keynote.
My guess:
The future performance of production and logistics relies on knowledge-intensive technologies, components and systems. The development of this strategic knowledge depends on a close collaboration between industry and academia in research projects and education initiatives.
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Please have look on our(Eminent Biosciences (EMBS)) collaborations.. and let me know if interested to associate with us
Our recent publications In collaborations with industries and academia in India and world wide.
EMBS publication In association with Universidad Tecnológica Metropolitana, Santiago, Chile. Publication Link: https://pubmed.ncbi.nlm.nih.gov/33397265/
EMBS publication In association with Moscow State University , Russia. Publication Link: https://pubmed.ncbi.nlm.nih.gov/32967475/
EMBS publication In association with Icahn Institute of Genomics and Multiscale Biology,, Mount Sinai Health System, Manhattan, NY, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
EMBS publication In association with University of Missouri, St. Louis, MO, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30457050
EMBS publication In association with Virginia Commonwealth University, Richmond, Virginia, USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
EMBS publication In association with ICMR- NIN(National Institute of Nutrition), Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
EMBS publication In association with University of Minnesota Duluth, Duluth MN 55811 USA. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852211
EMBS publication In association with University of Yaounde I, PO Box 812, Yaoundé, Cameroon. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
EMBS publication In association with Federal University of Paraíba, João Pessoa, PB, Brazil. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30693065
Eminent Biosciences(EMBS) and University of Yaoundé I, Yaoundé, Cameroon. Publication Link: https://pubmed.ncbi.nlm.nih.gov/31210847/
Eminent Biosciences(EMBS) and University of the Basque Country UPV/EHU, 48080, Leioa, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27852204
Eminent Biosciences(EMBS) and King Saud University, Riyadh, Saudi Arabia. Publication Link: http://www.eurekaselect.com/135585
Eminent Biosciences(EMBS) and NIPER , Hyderabad, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Eminent Biosciences(EMBS) and Alagappa University, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30950335
Eminent Biosciences(EMBS) and Jawaharlal Nehru Technological University, Hyderabad , India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Eminent Biosciences(EMBS) and C.S.I.R – CRISAT, Karaikudi, Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237676
Eminent Biosciences(EMBS) and Karpagam academy of higher education, Eachinary, Coimbatore , Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Eminent Biosciences(EMBS) and Ballets Olaeta Kalea, 4, 48014 Bilbao, Bizkaia, Spain. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29199918
Eminent Biosciences(EMBS) and Hospital for Genetic Diseases, Osmania University, Hyderabad - 500 016, Telangana, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/28472910
Eminent Biosciences(EMBS) and School of Ocean Science and Technology, Kerala University of Fisheries and Ocean Studies, Panangad-682 506, Cochin, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27964704
Eminent Biosciences(EMBS) and CODEWEL Nireekshana-ACET, Hyderabad, Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26770024
Eminent Biosciences(EMBS) and Bharathiyar University, Coimbatore-641046, Tamilnadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27919211
Eminent Biosciences(EMBS) and LPU University, Phagwara, Punjab, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/31030499
Eminent Biosciences(EMBS) and Department of Bioinformatics, Kerala University, Kerala. Publication Link: http://www.eurekaselect.com/135585
Eminent Biosciences(EMBS) and Gandhi Medical College and Osmania Medical College, Hyderabad 500 038, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27450915
Eminent Biosciences(EMBS) and National College (Affiliated to Bharathidasan University), Tiruchirapalli, 620 001 Tamil Nadu, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/27266485
Eminent Biosciences(EMBS) and University of Calicut - 673635, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/23030611
Eminent Biosciences(EMBS) and NIPER, Hyderabad, India. ) Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/29053759
Eminent Biosciences(EMBS) and King George's Medical University, (Erstwhile C.S.M. Medical University), Lucknow-226 003, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579575
Eminent Biosciences(EMBS) and School of Chemical & Biotechnology, SASTRA University, Thanjavur, India Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25579569
Eminent Biosciences(EMBS) and Safi center for scientific research, Malappuram, Kerala, India. Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/30237672
Eminent Biosciences(EMBS) and Dept of Genetics, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/25248957
EMBS publication In association with Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Hyderabad Publication Link: https://www.ncbi.nlm.nih.gov/pubmed/26229292
Sincerely,
Dr. Anuraj Nayarisseri
Principal Scientist & Director,
Eminent Biosciences.
Mob :+91 97522 95342
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Does production management using Internet of Things technology streamline production management processes and does it increase the economic efficiency of the company's operation?
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Best wishes
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Dear Mauro Luisetto,
Thanks for the kind words regarding the issues of this discussion regarding the issue of production management using Internet of Things technology.
Thank you very much,
Regards,
Dariusz Prokopowicz
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By 2040, a deficit of clear water will appear in most countries in the world.
On the one hand, the use of water in the production industry of various technical and automotive goods is growing, but also in some areas of food production.
For example, 1650 liters of water absorbs, for example, the production of 1 hamburger, because the production of meat absorbs very large amounts of water.
In addition, a progressive global warming process and more and more frequent droughts appearing in various places around the earth, mainly in the subtropics and in some places of the temperate climate.
In connection with the above, the question becomes more and more relevant:
How should you improve the economical sustainable environmentally friendly clean water economy?
How to improve the processes of purification of used, contaminated water?
How to obtain water develop technologies for desalination of sea water or condensation of water in areas subject to periodic drought?
How to improve the extraction of pure Oligocene water contained in the Earth's crust in desert areas?
Please reply
Best wishes
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One of the serious negative effects of the accelerating global warming process is the increasing drought, falling rainfall, drying up water reservoirs, ponds and rivers, and subcutaneous waters. According to the results of scientific research, water obtained from deep-sea deposits, which was formed during ice ages thousands of years ago, should not be used for watering lawns only for the most important needs, i.e. for drinking and hygiene. On the other hand, for watering lawns, gardens and farmlands, water collected from installations and retention reservoirs, in which rainwater is caught and collected, should be used. In addition, other sources of water used in various applications, including watering lawns, gardens, farmlands, should also be obtained from seawater desalination plants and sewage treatment plants.
Best regards,
Dariusz Prokopowicz
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Dear Colleague,
Part of my Ph.D. thesis needs to be completed questionnaire, which, unfortunately, due to Covid 19, we cannot attend the company under review. For this reason, I request supply chain experts who wish to complete the questionnaire to notify me, that I will email the questionnaire to them. It would be your generosity to respond to the questionnaires and also distribute them among your colleagues, students, and networks.
Thank you in advance for your help and cooperation.
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I would like to know about all the molecules that can be expressed by/in CD8 T cells
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Hi Fa,
Your question appears simple but there are several answers depending on the species (human vs mouse) and the state of the CD8 T cell activation.
Naive CD8+ T cells express CD62L (L-selectin) integrin, IL-7Ra (CD127), S1PR1 and CCR7 chemokine receptors.
They also express the costimulatory molecule CD28 and negative regulators of T cell activation such as TGFbRI and VISTA. These are all surface markers but they also express specific transcription factors such as Foxo-1 and KLF-2
Just after activation and during priming, CD8 T cells upregulate the expression of CTLA-4 and CD69 then later PD-1, and LAG-3 as well as Fas. As the CD8 T cells are primed for cytotoxic potential, they express Granzyme B (GzmB) and Perforin.
CD44 is an excellent marker for antigen experience of mouse T cells.
However, human CD8 T cells are different since naive cells are CD45RA+ CD45RO- while effector T cells are CD45RO+ CD45RA-
However, there are many more molecules than those I just listed. For a more comprehensive knowledge of these, please refer to these resources:
2-ImmGen is also a terrific resource where you can check for the expression of specific markers
There is one minor, yet important point to consider. The classically defined CD8+ T cell subset is the αβ CD8 T cell. However, there are also αα CD8 T cells which are part of intraepithelial T cells in the intestines.These cells do not express the β TCR subunit and their role in gut homeostasis remains unclear.
I hope this reply was of any help.
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I was wondering if ecosystem metabolism (GPP-ER=NEP) could be measured using BOD bottles that are not completely filled with water (dark-light bottle method). In such a case, which problems could come from this approach?
Do you have a reference that could be useful to discern which method to use?
Thank you!
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Despite green market thinking being here formally since 2012 Rio +20 conference finding a definition of a true green market is hard to find even in major publications dealing with green growth and green economies…the term green market a kind of disappeared as we moved towards an environmentally friendly world after 2012, and because it was left unattended in development and economic thinking circles this has led since then to confusion and misused of the term.
Many forms of environmentally friendly markets are called green markets, when they are not. For example, a Google search of what is a green market leads to the following definition in Wikipedia:
--The term "green market" refers to the fact that the resold goods are put back into productive use, which is the most environmentally friendly use of used or discontinued products--
But that is a definition of one type of environmentally friendly market, but that is not the definition of a green market. And this lead to the questions, what is a green market? What is not a green market?. Please feel free to comment, what do you think a green market is and/or what it is not; and why?
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In my modest opinion, green markets are markets where products and services that are less harmful to the environment or derived from the sustainable use of natural resources are traded. They are specialized in the use of goods and services that promote the sustainable use and conservation of natural resources. These markets Colombia has great potential due to its large amount of resources that can be used in a sustainable way and the possibilities of environmental improvement in different sectors.
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What modern, computerized information technologies in the field of Industry 4.0 are used to implement improvements in production logistics or other logistics areas, such as distribution logistics, supply logistics, transport logistics, etc.?
Please reply
Best wishes
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In recent years, the improvement of production logistics is carried out by optimizing the processes of managing the supply of raw materials, semi-finished products and prefabricated products to specific stages of the production process in accordance with the concept, e.g. just in time. The improvement of production logistics is also made through the optimization of the consumption of raw materials, energy, etc. as part of the improvement of technological production processes. The aforementioned improvement of technological production processes is carried out by implementing such Industry 4.0 technologies as smart technologies, learning machines, network development engineering, industrial Internet of things, automated machines and robotics, horizontal and vertical data system integration, multi-criteria simulation models, additive manufacturing, etc.
Best regards,
Dariusz Prokopowicz
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What types of restructuring processes are used to implement improvements in production logistics or other logistics areas, such as distribution logistics, supply logistics, transport logistics, etc.?
Please reply
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The SARS-CoV-2 (Covid-19) coronavirus pandemic, through its impact on economic processes in many production companies, accelerated the development restructuring processes implemented through the implementation of new Industry 4.0 technologies, including the use of smart technology, the Internet of Things, learning machines, robotics, artificial intelligence, cloud computing etc. and improvement of production logistics. Currently, many production companies are creating platforms that enable the implementation of team engineering projects implemented in the form of remote work and with the use of the so-called. digital twins of specific designed production processes, complex product designs, multi-stage technological, manufacturing, production processes, etc.
Regards,
Dariusz Prokopowicz
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Productivity is a key aspect of economic growth. However, it is also important to choose what should be produced with the growing importance of taking into account the issue of ecology, care for the protection of the natural environment.
Do you agree with my opinion on this matter?
In view of the above, I am asking you the following question:
What is the significance of the development of production and the productivity in modern economies?
Please reply
I invite you to the discussion
Thank you very much
Best wishes
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… Clearly, increasing resource productivity is the way to resolve conflicts between future development and heavy resource burdens … The primary requirement for long‐term resource productivity development is increased income levels leading to higher resource productivity …Gan, Y., Zhang, T., Liang, S., Zhao, Z., & Li, N. (2013). How to deal with resource productivity: Relationships between socioeconomic factors and resource productivity. Journal of Industrial Ecology, 17(3), 440-451.
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I am using the ANN for a product reliability assurance application, i.e.picking some sample within the production process and then estimating the overall quality of the production line output. What kind of optimization algorithm do you think works the best for solving the ANN in such a problem. ?
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Optimization algorithm in neural network
The process of minimizing (or maximizing) any mathematical expression is calledoptimization. Optimizers are algorithms or methods used to change the attributes of theneural network such as weights and learning rate to reduce the losses. Optimizers are used to solve optimization problems by minimizing the function.
Regards,
Shafagat
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What factors brought the euro value of the GBP from 1.5 euro in 2004 to 1.06 euro today?
A -41% loss, of the British Pound, that's a lot.
How could this happen?
Is it a cause a consequence of Brexit?
Does it reveal a weakness of the British Economy versus the Eurozone?
Is it an opportunity of increased competitiveness of UK, to export goods and services becoming cheaper if produced in the UK than in the Eurozone (UK vs Eurozone, comparable to Mexico vs USA?)
Your views?
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Teething problems are bound to occur soon after Brexit and I am not particularly worried by the weakness of the GB pound against the Euro.. Given the fact that billions of GB pounds have recently been negotiated and generated by the UK in new world economies, that the FTSE has gone up by 9 notches recently, that new world markets are currently being negotiated in New Zealand, the USA, Australia and the Pacific countries I am confident that the GB pound will recover handsomely. A word of caution. I am not an economist and do not profess expertise in high finance. The view expressed above is a layman's view based on what facts he knows of.
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Dear all, I am currently using Qiagen miRNA profiler plates (catalogue number: MIBT-659ZF-24) to identify deregulated miRNAs in cattle under certain physiological condition.
I have ordered the product and the product arrived as well, however I did not find any product manual and the plate layout of that particular product in the internet page of the company. If someone used it before can you please provide me the plate layout.
Thanks in advance.
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Hi Dr. Hasan,
Did you get the plate layout for 384 well formats? I'm looking for miRNA list on the panel, if you have would you please share it.
Thanks,
Ankita
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Every year, millions of tons of food of food are wasted in every highly developed country. How should the logistics of deliveries of agricultural products be improved and the consumers of food products to be more economical in order to economise the purchased food so that citizens do not throw so much food into the trash? How to change the habits of consumers? What institutions should still be created to take away unused food from consumers and, if it is suitable for consumption, efficiently, systematically transfer it to poorer countries in which food is lacking? In connection with the above, the current question is: How can the food waste in developed countries be systematically reduced?
Please reply. I invite you to the discussion.
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Yes, unfortunately the scale of food waste is still high. Systems and instruments for reducing food overproduction, logistics for transporting food products, storage and consumption should be improved. It is necessary to limit the scale of throwing away food products in order to reduce the waste of inputs, raw materials, energy and natural resources. In addition, limiting the overproduction and scale of throwing away food products also reduces the scale of environmental pollution, e.g. chemical plant protection products used in the production model of agriculture, reducing the scale of greenhouse gas emissions from intensive, productive livestock farming, reducing the scale of water consumption, etc.
Best regards,
Dariusz Prokopowicz
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Do the shortening of life cycles of technical products, electronics, household appliances, IT equipment, etc. used by producers is a solution to the potential problem of overproduction?
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No, This will create more overproduction.
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One of the areas that are among the greatest future achievements of the 21st century is the creation of artificial intelligence, which will find applications in various types of information systems used in industry and information services, processing huge data sets, Big Data database systems, forecasting and managing complex organizations. Currently, innovations are being created in various fields of production and services, generation of new technological solutions. New technological solutions, including technical, product, process, organizational and other innovations in their essence are the result of creativity and creative ingenuity of inventors. If innovation is inseparably connected with the human need of creativity of intelligence and perhaps also some kind of artistry, then whether artificial intelligence in the future will be able to replace man in these types of human creative activity. Will artificial intelligence be able to learn artistry in the matter of generating innovative technological solutions, will it create innovative technologies according to strictly or generally defined determinants, defined variables, determined factors? Will artificial intelligence be able to generate innovative technologies as a response to the question asked for the Smart Data database system?
Please reply.
I invite you to the discussion.
Thank you very much.
Best wishes.
Dariusz Prokopowicz
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Artificial intelligence must build its own "Cheops Pyramid"... people will not be able to understand it
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Logistics of production + Business Intelligence + Internet of Things + Learning machines + Internet + Big Data = Advanced analytics supporting production logistics processes?
Is the combination of currently developed technologies of Industry 4.0, ie above all advanced information technologies: Business Intelligence + Internet of Things + Learning machines + Internet + Big Data and Internet ICT and their application in the field of production logistics will lead in the next years to the emergence of advanced support analytics production logistics processes, including the development of production e-logistics?
Please reply
I invite you to the discussion
Thank you very much
Best wishes
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... Industry 4.0 is expected to have a significant impact on supply chains, business models, and processes in order to achieve an MSC. Researchers use different names for Industry 4.0 in the supply chain management context: digital supply network (DSN), Internet of Things, E-Supply Chain, Supply Chain 4.0, E-logistics, or Logistics 4.0...Industry 4.0 increases digitalization and automation in manufacturing, and creates a digital process to facilitate interaction among all parts of a company. By implementing Industry 4.0 in the supply chain systems, four main SC elements—integration, operations, purchasing, and distribution—are affected and can increase the productivity of companies as well (Kayikci, 2018).... The main benefits of Industry 4.0 in the SC are to reduce the lead time for delivery of products to customers, reduce the time to respond to an unforeseen event, and to prompt a significant increase in decision-making quality (Barreto et al., 2017).... Industry 4.0 can help companies afford complicated and dynamic processes in their SC and to handle large-scale production and integration of customers (Rennung et al., 2016).... Industry 4.0 can bring positive benefits in current sales and operations planning and also in the logistics process (Santos et al., 2017).... After implementing Industry 4.0, real-time information can be shared across this digitalized process to drive useful decisions. ...
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What could be the main design challenges in aquaculture engineering? in what kind of aquaculture sector?
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I think...it all about the countries....which really pay attention on the design or not...I mean limitations generate the ideas some time...RAS is not that popular in India but it popular in other countries.... similarly bund breeding is quite famous in India but less in other countries...if we will think about cage western world is leading but still in so many countries...it's not up to the mark...so i think all the aquaculture enngg design need to work out efficiently....
Further I would like to suggest about the vertical farming model...which may be very useful in the coming future..
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As you know, The piezoelectric and FGM can be used in the faces of sandwich structures, concurrently. What is the procedure of production of this kind of sandwich?
What is the goal of using piezoelectric and FGM in sandwich structures, concurrently?
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FGPM is a kind of piezoelectric material intentionally designed to possess desirable properties for specific applications, and featuring material composition and properties varying continuously in desired direction(s). Smart structures or elements made of FGPM are thus superior to conventional sensors, and actuators are often made of uni-morph, bi-morph, and multimorph materials. This is because, for piezoelectric laminates with layered materials having homogeneous properties, large bending displacements, high-stress concentrations, creep at high temperature, and failure from interfacial bonding frequently occur at the layer interfaces under mechanical or electric loading. These effects can lead to reduced reliability and lifespan.
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Hello! I'm a graduate student and this is my 4rd month in lab. Because of my project coworker is quit, Im the only one in ROS project. And I dont have a great background about that. Our first goal is production of ROS by chemicals so May you help me about this ? Maybe about literature survey or protocols? Im so confused since Im so new about researching. Thank you.
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Dear Dilara,
For production of superoxide anion radical by chemicals you can used KO2. But after addition of KO2 to aqeous solution, the superoxides are disproportioned with formation of H2O2. So if you need to have a solution of superoxide you can prepare the solution by dissolving KO2 with DMSO (dimethyl sulfoxide) in the presence of 18-Crown-6 (1,4,7,10,13,16-hexaoxacyclooctadecane). The superoxide is stable in this solution for several hours.
For enzymatic generation of superoxide you can used the oxidation of xanthine by xanthine oxidase. The method is widely used for generation of superoxide and you can easily to find in many papers.
For production of hydroxyl radical you can use the Fenton reaction which is
M+(n-1) + H2O2 = M+n + OH- + HO•
where FeCl2 is usual used as M+(n-1)
So you can prepare the solution of H2O2 and then add FeCl2
The most usual mechanism of singlet oxygen generation is photosensitization, i.e. reaction of 3O2 with a photoexcited dye molecule (1S*). 3O2 is a ground state of oxygen.
1S* + 3O2 = 3S + 1O2
Rose Bengal is usual used as a dye molecule. So 1O2 can be produced by illuminating of solution in the presence of Rose Bengal. The rate of production is depended on light intensity and concentration of dye.
Information about detection you can find in this review
Mattila H., Khorobrykh S., Havurinne V., Tyystjärvi E. (2015) Reactive oxygen species: Reactions and detection from photosynthetic tissues. J Photochem Photobiol B., 152 (Pt B), 176-214.
Best regards,
Sergey
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Imagine there are NO production costs, neither economic costs,…..
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How production would be priced then?
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And this answer brings the question: How perfect market competition theory, short term and long term, would look like under full cost externalization? What are the sustainability implications of this?
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Any ideas!
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Note: This question and answer are related to my current project/article on the works shared below: “The road towards sustainability markets: Linking cost externalization to market structure and price structure using qualitative comparative means. https://www.researchgate.net/project/The-road-towards-sustainability-markets-Linking-cost-externalization-to-market-structure-and-price-structure-using-qualitative-comparative-means
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You are right to state that, under the current economic conditions, money is access to energy, i.e. your mind game, Lucio, requires a different monetary system, where the money supply is tied to a clean energy index or the like. Coasian bargaining could be a helpful tool to develop such an economic thought model. Economic systems evolution does not happen from alone, it requires creative thinkers like you, who anticpate alternative pathways for the eco-logical working of future markets. Concerning horses, our last working horse (‘Rudolph’) for farm work died in 2012, but I never went to school by horse, only by a little donkey (‘Francis‘).
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What do you think about the interest of algae?
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Global demand for algal foods is growing, and algae are increasingly being consumed as functional food. Please see the following RG links for details.
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I need an article, paper, book, etc. for mixed or multi-model of assembly line problem. However, any article related to multi-objective ALBP is very useful for me too.
Obviously, the difference between the mixed model and the multi-model line is the batch sizes defined for various types of products in multi-model ALB.
Regards,
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Dear Nima Pasha,
I recommend an article that describes the solution to a mixed or multi-model pipeline problem.
V. E. Lelyukhin and O. V. Kolesnikova, "Strategy for the Formation of Production Plans for Small-Serial Machine-Building Enterprises," 2019 International Science and Technology Conference "EastСonf", Vladivostok, Russia, 2019, pp. 1-6. doi: 10.1109/EastСonf.2019.8725334
Regards,
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The production line is arranged so that the product is moved sequentially along the line and stops at work centers along the line where an operation is performed. The lean six sigma is to eliminate mistake, reduce cost and to improve efficiency by cutting unnecessary steps.
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There is a strong connection between the way assembly lines are planned and organized, and common Six Sigma practices and principles. It should come as no surprise to anyone experienced in either of the two fields that there are some very strong positive implications in both directions, and it’s a good idea to understand the general idea behind assembly lines as a leader trying to implement lean principles in their organization. And to that end, Six Sigma offers a very powerful set of tools that can help you progress through the field at a rapid pace.
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I need to know the emissivity values of vegetation cover and water bodies from a MODIS product MOD11A2 and there are two bands 31 and 32, which one to be used and what is the difference between them both? Also, is there any better product for the emissivity?
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I would ask ask a question in line with this conversation topic. I am looking for Land Surface Temperatures at night time with satellite data that covers Europe. Modis offers some interesting data at night with a resolution of 1km, for example water vapour. On the other hand, there are some strategies to obtain LST with Landsat 8 by previously calculating the NDVI and use it in combination with the TIR band. Do you know another strategy with which I can get the result with the greatest rigor and spatial resolution as possible? Thanks in advance.
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I am doing a research on impact on purchase behavior of millennials when they come across green products or Eco-friendly products. I need to find the gap in this research. 
Thank You
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read this article on Green products and factors effecting PI of green products.
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I'm looking for ways to make release agent transfer visible. In the RTM process (Resin Transfer Moulding) the release agent is used to facilitate the removal of the composite semi-finished product from the mould. How can one make visible whether and how much release agent remains on the component?
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Dear colleagues,
how are you?
Indeed, I do completely agree that LIBS would be a promising technique!
Moreover, based on the fact that changes of the wetting behaviour might occur due to transfer of release agents, also the larger-area aerosol wetting test (AWT) might be an option for detecting the presence of release agents (and for smaller coverages AWT might even differntiate bewteen distinct layer thicknesses of release agent).
I might indicate a publication following the subsequent link
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In my openion, the chemical industry is one of the most important industries in the world. Not only do 90% of our everyday products contain chemicals, but the industry also employs approximately 10 million people. Naturally, they were one of the first to embrace digital technologies such as process control systems or sensors which have a long tradition in production.
A continuous digital transformation plays a crucial role in several key aspects of the industry. Accenture has identified the six most influenced areas.
  • Higher Levels of Efficiency and Productivity
Increase competitive advantages and further decreases the costs through operational optimizations.
  • Innovation through Digitalization
Helps boost the productivity in R&D and thus decrease the time till market entry.
  • Data Management and Analytics
An improved understanding of customer needs and so the optimization of offerings are integral contributors to any company’s success.
  • Impact on the Workforce
Tasks and opportunities, as well as the job requirements, will experience a change with digital transformation. “Finally, technology will take an even greater role in upskilling and training employees, and in knowledge management.” (World Economic Forum & Accenture, 2017)
  • Digitally enhanced offerings
An increasingly important aspect of product performance especially for close-to-end customer markets.
  • Digital Ecosystems
Being separated into Innovation, Supply and Delivery, and Offering Ecosystem.
Industry 4.0, however, does not only include aspects of digitalization but mainly artificial intelligence, robotics, Internet of Things (IoT) or advanced materials. In the table below their impact on chemical products is illustrated.
Please elabotate are your thoughts about it also.
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Thanks, clear!
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What do you think are most important foci of an ecosystem approach (following James J. Kay and others; see attached!) to integrate production, supply and consumption in the context of global sustainability?
Is it e.g. scale-based spatial considerations, demography, urbanization dynamics, stakeholder (value) governance, or some distinct levers in production, supply, or consumption (LCA, SOM, Responsible Consumerism?), or something else?
If anything, where do you see priorities or research gaps?
The question is deliberately "open" and broad, as not to prejudice answers.
Thanks in advance for a discussion.
K.
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Such integration is often complex and needs to consider a nested system of multiple scales and strategies. A Multiscale Ecosystem Framework can be used to achieve such a deliberate design. Here is a link to my article:
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The biggest impact on consumer spending, consumer purchases, market behavioral behavior of consumers purchasing technological products generate, inspire through advertising campaigns, public relations, sponsored articles, etc. technology companies that these technological products produce and create new standards, develop new technologies, shape new tastes, preferences, interests, fashion of consumers.
Large corporations that dominate on specific technological markets, corporations allocate a significant part of their financial surpluses for development purposes, including the creation of new technologies, new types of technology products, new technology standards and allocate large financial resources to advertising campaigns to inform consumers about new types of products, gadgets technological and thus influencing, shaping consumer preferences.
Do you agree with my opinion on this matter?
In view of the above, I am asking you the following question:
What is the impact of technology companies that produce technology products on consumer purchasing preferences?
Please reply
I invite you to the discussion
Best wishes
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An increasingly automatic consumption that demands greater speed in the management of the entire purchasing process, an onmicanal consumer who makes his purchases on-line, off-line and click & collect (online purchase and pick up in store), with greater purchasing power due to disintermediation and greater information through direct channels such as mobile applications, are some of the changes or trends in consumption.
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Can advanced data processing in the cloud, Big Data database systems and Business Intelligence analytical platforms be helpful in the processes of restructuring and improving logistics of the functioning of production processes?
Please reply
Best wishes
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Notably, the significance of supply chain management and and the ways by which it will facilitate and improve production processes is known to those involved in modern industrial enterprises. This requires much IT investment which in turn depends on managing and maintaining big data. In point of fact, large data sets are required to analyze computationally to reveal patterns, trends, and associations which may shed light on logistics management and production engineering . However, promoting sustainable development simply encourages technological advances that are a threat to the earth's resources. As such, the use of big data analysis and interpretation should aim at enhancing Green Logistics in order to help the effective functioning of production processes.
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Dear respected colleagues,
Kindly help me dissect this postulation and submission below. Can this argument be correct ? "Energy production does not grow economy, but energy consumption does...". How possible is this assertion?
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I am very skeptical of such general statements. They sound very good and render those who make use of them look very good because of having put together the problems of the world in one slogan. You have better taken a look at the different societies, political systems etc. The current political turmoil in Venezuela one of the countries in the world well endowed with hydrocarbon deposits vindicate this statement, while the countries along the Trucial Coast would contradict this statement. In this case the political and social systems are very much different from each other and they have a much greater say than the energy resources. There are energy producing countries such as Norway which exert a rather perspective strategy and use the current production of energy to establish industries in new technologies. The quintessence is, you have to treat each country as a separate entity and take into consideration a wide range of aspects before you create a general statement like that. H.G.Dill
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I am analyzing the turnover of fine roots in floodplain forests. My first results show that sometimes the values of production, mortality and decomposition are below zero. I did not find any similar results in the literature. Some papers only showed production = 0, but it was never negative. Did I calculate something wrong?
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can you elaborate your method of calculation?
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Why do consumers, when shopping for specific products and services often accept a limited range of information regarding, for example, production technology and composition in terms of the raw materials used?
Have consumers become used to the fact that in many markets there is no full, perfect competition? Perhaps the information resources of the Internet, the processing of data downloaded from the Internet in the Big Data database systems technology will increase the level of consumer knowledge about particular products and services.
As a result, consumer product and service markets would become more transparent and consumer-friendly.
In view of the above, the current questions is: Why do consumers, when shopping for specific products and services often accept a limited scope of information regarding, for example, production technology and composition in terms of the raw materials used?
Will the development of marketing in new online media or digital media change? Will emerging markets in the e-commerce formula increase the level of competitiveness due to the increased availability of consumer information?
Please, answer, comments. I invite you to the discussion.
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Consumers are not from technical field.so they want that the product should satisfy their needs , rest is not their business
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These types of questions have appeared many times in every era of the technological and industrial revolution, the period of accelerating technological development. These types of questions have already appeared in the periods of increasing the scale of objectification, arming technical human labor, from when the processes of manufacturing goods in manufactories transformed into mass production. This was the case during the Industrial Revolution of the XIX century, when the invention of a steam engine significantly accelerated the development of industry and mass production. Then, the introduction of tape production in various branches of mass production in the early twentieth century. In the second half of the twentieth century, ie in the era of subsequent stages of mechanization, automation, then the computerization of the production of many mass goods, this question appears again. Through these periods of technological progress, national economies have been transforming structurally from agricultural, industrial to modern-day domination of services. At the same time, the importance of new generation factors, which include information, technology, entrepreneurship and innovation, was gradually growing. Some branches of industry were shrinking, others were growing in the whole production of goods in the economy. At the same time, new professions, professions and specializations of human work were created, related to information, IT, analytical and technological services related to the development of new fields of knowledge and technology. So the earlier fears about the lack of work for people in connection with the technical progress that took place over the last several hundred years turned out to be essentially exaggerated. However, currently the same questions reappear: Can the development of robotization and computerization cause a significant rise in unemployment in the future? If such questions arise, then we are dealing with another era of technical progress or another technological revolution. The attributes of this revolution are also increasingly added to the development of new online media, computerized computing techniques, artificial intelligence, machine learning, Big Data, etc. in the applications of such areas of knowledge and science as biotechnology, metrology, ecology, energy, communication, medicine and many other fields of life science and new tech. In connection with the above, please answer the question: Can the development of robotization and computerization cause a significant increase in unemployment in the future?
Please, answer, comments. I invite you to the discussion.
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If such development would be accompanied by greed and selfishness (which is usual, unfortunately), then definitely there will be an increase in unemployment. All technology development accompanied by ethics shall ensure development to humanity, including effective employment (as new business shall be born as mentioned in question and answers ).
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Do you have some thoughts about automation of process?
Smth like: 'Insects as Sustainable Food Ingredients ' https://bit.ly/2Kacfdc
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I have reared mealworms for 5 years, being part of my reseaerch. The simplest method to rear mealworms is to provide cut potatoes plus bran in large bowls and to cover the top of bowl with cloth. leave the bowl untouched for about 15 to 30 days. you can also read my paper.
A comparative toxic effect of Cedrus deodara oil on larval protein contents and its behavioral effect on larvae of mealworm beetle (Tenebrio molitor) (Coleoptera: Tenebrionidae).
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What are the problems encountered with carotid shunts that are used in carotid endarterectomy and their possible solutions?
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The answer above is incorrect....firstly the overall flow through a carotid shunt is quite small,and secondly,it is only performing the job of the native artery,bypassing it whilst the carotid is clamped and operated upon.
The real issues with carotid shunts are as follows:
1.Decision making process in inserting a shunt may take time,and in some cases may be incorrect,thus relying on good perioperative techniques for measuring or quantifying adequate cerebral blood flow such as TCD and INVOS.
2.Inserting the shunt into the carotid artery can result in dislodging plaque material distally during insertion,or occasionally dissection.
3.The shunt can be placed too far down into the common carotid,and may enter the subclavian origin and occlude flow to the arm,or lose flow through the shunt.
4.The shunt can be dislodged or blown out of the artery,neccesitating reclamping and replacement,with all of the above risk factors.
5.The shunt can interfere with visualising the operation site and may impede surgery to a small degree.
In short,if there is a lack of adequate monitoring of cerebral perfusion,a shunt can be thought of as mandatory by many,but if there is reliable and validated cerebral monitoring(such as INVOS or TCD),then shunting should only be performed where indicated.
Hope that helps.
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Glue is discharged from a syringe tip at a constant pressure P through a constant time period t.
The original tip is of diameter d1= 0.20 mm. A new tip is used of diameter d2 = 0.25 mm.
Considering only the tip of the syringe i.e. constant length and constant diameter, does the flow rate (be it mass flow rate or volumetric flow rate) decrease with the new tip for P and t ?
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For an increased diameter and constant pressure, the volume flow of your fluid should be increased significantly. This is actually quite easy to calculate for newtonian fluids. However, as you describe your fluid as "glue", it may have all sorts of strange properties.
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What do you think extra ordinary economic growth of China in last three decades is dependent upon what?
- Cheap labor
- Economies of Scale
- Low production cost
- Globalization
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Rai, thought I'd upload my work on the matter, even though it was publish about a year or so ago.
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1. propylamine react with HCl ? it will be formed solid or not?
2.my compound is amino functionalized silsesquioxane .it's a solid neverless it react with HCl? it will  give desire product?
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Amino functionalized silsesquioxane can be prepared only as a hydrochloride or trifluoromethanosulfonate (solid). It is also can be prepared as a neutral aminopropylsilsesquioxane, but it slowly decompose. Better is using Et3N for generation in situ aminogroup.
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Dear Collegue
would you provide me some Details and Pictures please ? iam activ in Africa and let us perhaps cooperate ? who knows
Regards
Heinz
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Sehr geehrter Herr Buchroithner
Vielen Dank für die Infos. Kann ich sehr gut gebrauchen im Gesamtprojekt, für Afrika.
Gerne sende ich Ihnen per Mail eine Kurzinfo darüber ! Wie lautet Ihre Mail Adresse bitte ?
Gruss aus Bonn
Heinz J. Sturm
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Hi everyone,
I have a task for my college study, about the formulation of sublingual tablet. can anyone tell me about what is actually the sublingual tablet is, like the characteristics, what the requirement for the substance that can be formulated as a sublingual tablet, what the evaluation test that should be we do after the production? 
and maybe someone knows the literature that i can read it, especially about sublingual tablet formulation. 
Thanks. 
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Drugs having lower dose, problem with oral formulation, problem of first pass metabolism, irritation in GI tract can be converted for sublingual tablet formulation.
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I need to use the PCR product as a standard hence I need accurate concentrations
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I agree with Mr. Hawkins. If your primer pair is specific and your reaction is efficient, your amplicon product should heavily outweigh any other DNA species in your reaction.
This might be obvious, but the best way to measure DNA concentration using PCR would be to take your product and rerun it (as starting material) using a standard curve protocol. Of course, if you had standards for a standard curve, you probably wouldn't be trying to develop your own standard. :)
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Will NaOH or KOH neutralize L-histidine hydrochloride? And how can we separate products from each other if it will?
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Hi Viktor
Yes, I think you are on the right track.
Dissolution of L-histidine hydrochloride monohydrate in a minimum volume of water will give you the aqueous protonated form of L-histidine, chloride and a water molecule. Addition of a molar equivalent of a strong base such as NaOH will give you aqueous L-histidine. Partial evaporation of the water should lead to the crystallization/precipitation of L-histidine (full evaporation will give L-histidine and NaCl).
Alternatively, you may also be able to obtain L-histidine directly from L-histidine hydrochloride monohydrate by mild heating at 100 oC, liberating HCl(g) and H2O(g). If you are going to try this, do the experiment in a fumehood due to liberation of HCl(g).
Geoff
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Dear Triple Quadrupole users
Is there anyone out there who could help me to better understand the following? I am working with a triplequadrupole LCMS and there are some settings that I find confusing .For an SRM method I can specify the peak width which has to do with resolution and the  scan width which is associated with Q3.Is there a scan width associated with Q1? Why do we scan the quadrupole in an SRM method?
To be sure that I understand it well, can anyone tell me that by the following settings : Q1:0.7  Q3:0.7  Scan width:0.002  Parent mass:500 Product mass: 200 what mass range Q1 and Q3 allows to pass through?
Any kind of help is much appreciated
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SRM means you're selecting the precursor ion (m/z 500) in Q1, fragmenting it in the collision cell, then allowing only it and the product ion (m/z 200) to pass through Q3 and be detected. You do this in order to monitor specifically for the m/z 500 ion because it may be of low intensity or because there is an overlap with another ion or what have you. Sensitivity and specificity can be improved quite a bit using SRM (or MRM). To select the ion, you need a reasonably narrow scan window in Q1, so that you don't pick up neighboring peaks at, say, M+/-1. Hence the setting 0.7 you mention for Q1. That shows a less-than-unit resolution. I don't think you need this to be that small for Q3, because increased resolution reduces intensity. You may want to do some tuning, play around with the settings and optimize.
"Scan width" is downright silly when it comes to SRM, because you're interested in only one of the potential fragment ions. If you were doing a regular CID experiment, then you can select your scan range or width to taste.
An amusing and instructive thing you can try is inject a well-behaved (MS-speaking) salt, such as acetate or formate, of an element with several isotopes, such as gallium; then select one precursor-ion isotopologue in Q1 but choose a wide enough window to be able to pick up both (Ga has two); then do CID and observe the fragmentation pattern. Then play with your parameters and see what happens. Never miss a chance to tinker.
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I need to know this for trypsin assay 
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There are many factors that affect an enzyme's activity like pH, concentration, temperature, cofactors (Ca), coenzymes (ATP), sample matrix (it could be an enzyme killer)...  The published Km is for that individual experiment and can vary significantly.
Do you really want to screw up?  
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When i searched for column chromatography, there was indicated amount of loading for coulmn diameter. For example 5g for 5mm diameter column. 
I wonder what indicated amount means?
Amount of reaction mixture or starting material or product?
I think amomg these there will be an answer.
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That is generally the loading of the crude mixture. The number you mention is just a guideline, since if TLC shows a large Rf difference between the product and impurities, you can use a higher loading. When running TLC for this purpose, keep the Rf of your product between 0.5 and 0.2 as this will give a good estimate of how the column will run.
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I would like to customize a mobile application for data collection purpose? Is there any source or articles that i can look on? It can be using open source or Esri products?
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Try looking at iOS' ResearchKit or Andriod's ResearchStack.
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Greetings!
I am conducting a research on what people (employees) do when innovation occurs in the workplace. Think of innovation in terms of creativity, creative problem solving, improvement of product and services and creation and development of new products/ideas etc.
Please participate in the survey by clicking the url: https://www.esurveycreator.com/s/5dcd791  .
Thank you for taking the time to read and participate in this research.
Note: if you are interested about the findings of this research, please email me at dhiman.chowdhury@yahoo.com or d.d.chowdhury@rgu.ac.uk
Dhiman Chowdhury,
Department of Management
The Robert Gordon University
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It's different depending on their age, flexibility and the question for whom this innovation is a benefit - the financial product, the efficiency, the work-life-balance of the employees. In the later case they will much more likely be willing to accept it. Maybe there can be found sensible compromises. Then it should be possible with most employees to introduce innovation. It depends on the chef's ability to realize and communicate win-win-situations. Does this answer your question? Arne Matthias