Questions related to Process Design
I have developed a mathematical model for modeling and optimizing process design. Now there are measurable input data available to compute other parameters via the model. I need suggestions on Open Source software and applications that are user friending that I can use to write my mathematical model equations to automatically calculate the measurable inputs are keyed in.
Software outside the usual programing and coding using MatLab and Python interface.
When observing the current scenario of the production plant of the automotive industry 4.0, all the machines and production equipment, the other technological innovations: IoT, AI, Big Data, Cloud, M. Learning etc, all connected by wireless networks and their sensors infrared and clusters operating in series, within the processes designed by the Engineering Center and by Logistica. In this scenario, it is necessary to ask:
a) In your opinion, are the activities performed there meeting the OHS conditions required by OSHA/ILO, not exposing employees to new and different occupational hazards in their tasks?
b) Within these new practices, systems, interpersonal relationships, new tasks and work processes, required of workers by the new technologies installed there, it is possible to identify new risk factors that show a relationship of danger, in this new work environment of Industry 4.0 ?
c) If the answer to item a) is POSITIVE, can you point out examples of safety item or condition at work, of these new tasks?
d) If the answer to item b) is POSITIVE, can you name and describe the new risk factors that you believe exist in the new environment?
e) In your opinion, do you believe that in Industry 4.0, there are better conditions for Occupational Health and Safety than in the old manufacturing industry?
f) What can you suggest to improve the current operational and safety conditions at work, in the industrial process 4.0?
Dears, I will be happy if you answer my questions for I increase my doctoral thesys studies. Thank you very much for all.
I have a plug flow reactor with two parallel equations taking place simultaneously inside it. I am not able to see any conversion in the stream summary table. It is despite the fact that I have input proper kinetic data and proper inlet/outlet conditions. Does anyone have a clue about it?
In a design I'm working on, we're thinking of removing the NaOH from a aqueous solution by using ion exchange columns. This will adsorb Na+ ions onto the resin and produce H2O. Regeneration is possible using HCl (which will produce a solution containing NaCl) or H2SO4 (which will produce a solution containing Na2SO4). Since in the same plant NaOH is used as a reactant, is there any way to recover the Na and re use it? Which is usually the most economically feasible?
Thank you in advance!
I want to estimate cost of a PSA system for hydrogen production. Required cost is only high level estimate, and numerically solving a complex system of PDEs is out of scope of the project. I am looking for alternate methods to estimate the PSA size.
How I can design or calculate the aeration tank volume of the Extended aeration sludge process design? The COD = 1800, BOD 600, TSS 300 and TKN 200. If COD needs to reduce to 70. (Units are mg/L). I just need to process of design or formula or just give the way...please. ?
I want to know if multi-tubular reactor can be customized through ASPEN Custom Modeler for simulation of Polymer synthesis reaction. Please let me know if there is any related code or method.
i can use cadence genus as well, i have 90nm SAED library for synopsys but need 45nm or 65nm for my research
Recently I have designed a automated gas leakage detection system using IoT. Now I want to analysis it further. What is the process to design/summarize it's control system.
I'm looking for correlation for density and viscosity of sodium hydroxide in function of concentration and temperature in range of 0-140 degrees Celsius?
We are soon starting with a project on assistive technology and work process design in manufacturing for supporting an ageing workforce and facilitate their health.
Do you know examples, projects, papers, etc., that may be useful in this context? Any experiences with such projects?
Looking for interest in developing a novel system to produce pure CO2 from methane. The application is for EOR projects where a source of CO2 is not readily available, but there is, or will be, associated gas with oil production. Rather then flaring this gas, it would be used to generate a pure CO2 stream for re-injection, as well as electrical power for the injection system. I'd like to discuss the thermodynamics and practicalities. System could also be used for geosequestration from a power gen system, but may only be break even...
Business process design projects are considered as knowledge-intensive work, because different analysis perspectives should be taken into account and multidisciplinary teams should be involved in order to generate design solutions. In that case, what knowledge should be considered in business process design projects?
Hello and Thanks in advance.
I’m fairly new to Biology so please bear with me here.
I’m currently in the process of designing an experiment using ELISPOT assay to detect antigen specific CD8+ T cells isolated from vaccinated mouse spleen. The peptides I’m stimulating the cells with are predicted to be MHC class I restricted just like how the reference papers suggest. However, I do not understand how a simple treatment of purified peptide would end up being presented by the MHC class I molecules by the antigen presenting cells. My understanding is that exogenous proteins are usually presented by the MHC class II molecules, therefore are targeted by CD4+ T cells.
Are there free “empty” MHC molecules that are just sitting on the membrane of the APCs that readily loads the treated peptides? But I thought class I MHCs need to have peptides bound in the ER in order to mature/fold properly and transported to the cell membrane.
Do the peptides go through endocytosis and then get released into the cytosol to go through the regular process that other degraded peptides go through? (Transported into the ER via TAP then get loaded onto the MHC)
I hope my question makes sense to some degree.
Again really appreciate the help.
Would also very much appreciate any other comments regarding ELISPOT assays for future tips :) such as why are DCs used as APCs when most nucleated cells are use MHC class I molecule.
As we know the executions of any business process is not possible without its data. In particular process designers have to know data scope (data model) as well as the way data is processed during BP execution.
BPMN does not allow us to include all the information about data structures nor data flows.
What in your opinion is the best way to show above mentioned data properties in business process diagrams?
Good structure of the data warehouse depends on good preparation for all of factors encountered by the process of designing a data warehouse. We are all aware of the rapid increase in the volume and accumulation of data. Platform for placement of data is of great importance and all further processes depend on precisely from this platform.
Researchers in the field of wheat development and improvement will already know that there have been 2 confirmed Sucrose Transporter Genes (SUT1 and SUT2) that have been identified and confirmed in Triticum aestivum so far. I am working with these genes and 3 others (SUT3, SUT4, and SUT5) from rice as i have found similar sequences in Triticum. Am very new to crop biotechnology field and currently in the process of designing my first set of primers. Later in my work, am planning to do yeast 2 hybridization and co-immunoprecipitation. I have a hypothetical pathway of gene certain gene interactions with sucrose that i would like to work towards proving. So my question is, "is there any particular experiments that i could do whereby i can show sucrose interactions with multiple genes simultaneously or is it 2 genes at a time?" Also as I mentioned i am quite new in biotechnology, so any advice on experimental skills or wheat growth or good lab practices would be highly appreciated.
Thanking you in advance.
Does anyone know any software or method or a good paper or book that proposes how to build an optimum plant layout.
For example think that we already have a plant and we want to extend it. Where to put the new components and pipes to have the best and optimum layout.
Thanks for your time and consideration.
I am in the process of designing control strategies for a 2-DOF helicopter (TRMS) and hence I would like to test my strategies while the helicopter performs some of those complicated manoeuvres .
I am in the process of designing an experiment in which I am hoping to induce a medium-term inflammatory response. I was considering using repeated LPS injections over a week or so, and have also been considering time-release pellets to release a constant amount of LPS into the system daily. I am concerned about the possibility of endotoxin tolerance, but have not found any literature on endotoxin tolerance during LPS exposure, only in a "preconditioning -> gap -> subsequent LPS challenge" type of model.
Is endotoxin tolerance dependent on a gap between challenges? Or is there evidence that it would occur gradually over the course of constant administration of LPS?
Any guidance or links to published reports would be much appreciated. Thank you!
My question is about the simulation of an internally heat integrated distillation column (HIDiC) by using as software ASPEN PLUS. My main question is related how to calculate the exact amount of heat that can be exchanged in each stage between the rectifier and the stripper?
Thank you in advance!
I am in the process of designing a digital controller for level control of a coupled tank system but I am not sure how to select the sampling interval for the control signal. I believe there is deep relationship between the sampling interval and the time constant of the system under consideration. I also came across a website where it was stated that " Sample time should be 10 times per process time constant or faster " but I am not being able to find any good journals on that.
Can anyone please help?
I am doing a project in which i will have to provide an analytical financial viabiliy of the above two processes.
I am doing research report about Discuss the interrelationship between materials testing and engineering process for [ Design and Manufacturing ]
I am in the process of designing a suitable objective function (fitness function) for the optimization of certain parameters of a controller. I would thus like to look into some good examples of cases where a good amount of effort has been spent towards the design of a suitable objective function. Good textbooks and papers from good quality journals are most welcome.
I'm currently doing research on the process of analysis of visual sources of inspiration. As part of the collection of information I'm conducting a survey aimed at people with a background in Design and teaching.
The research is focused to a better understanding of the analysis of visual stimuli and their analogy with the learning process.
The survey is completely anonymous and will not be asked for any personal information. Your participation would be a great help for the development of the research. Thank you very much for your time!
The link to access the online survey in English is:
Estoy actualmente realizando una investigación sobre el proceso de análisis de fuentes de inspiración visuales y como parte de la recopilación de información estoy realizando una encuesta dirigida a personas con experiencia en algún campo del Diseño y en la docencia.
La encuesta es completamente anónima y no se pedirá por ningún tipo de dato personal. La investigación está dirigida a entender mejor el análisis de estímulos visuales y su relación con el proceso de aprendizaje.
El enlace a la encuesta en Español es:
I know that between MTP & MTO process is differences in catalyst type and operation condition such as temperature range,…. and process design (recycles and reactor construction).
But my doubt is in exploring an exclusive kinetic and mechanism for MTP process.in other words for review, and study kinetics and mechanisms of MTP process, the proposed kinetics for MTO process can be useful? Or must restrict my research explore in “MTP kinetics” only.
I am researching on the challenges of managing sludge from Waste Stabilisation Ponds as compared to those of Activated Sludge Plants and other conventional wastewater treatment systems used in developed/developing countries. What are the grey areas to look out for by new research? Can anyone share experiences from the field, as well as relevant material with data on process design, operational and economic performance monitoring and retrofits?
I want to build a process dealing with non corrosive gas where the valves will switch their positions every hour (max). So in order to minimize the energy consumption, I was wondering if there is any kind of valves which require energy only during the position switching and not during all the time where the valve is open (if the valve is normally closed)
I am interested to know what will happen if two reactors are operated in parallel (the idea is separate HDO and HC). Also I was wondering if the operation condition (i.e. pressure and temperature ) in reactor A and B will differ each other. Can anyone would like to share the challenge of the reactor design? And it possible to separated water coming from reactor A (HDO) prior to second reactor B (HC)? I would appreciate for your kindness and helpful. Thank you
I am a young researcher and I recently started my PhD project, which will largely be centred around the practical aspects of continuous crystallisation by spray drying. I was hoping to benefit from your expertise and the diversity of each of your individual backgrounds related to this subject.
What do you think are the major aspects related to the applicability of spray drying in the pharmaceutical industry? Would you consider utilizing spray drying as a crystallization process? Based on your experience, can you recommend where computational modelling can be used to best effect to support a conceptual process design?
Thank you very much for your time! I would appreciate your feedback.
Kind regards, Frederik
I am in the process of designing an OMT at lower Ka band (18.1-21.7 GHz).
I'd like to validate the scattering parameters of my design by simulating the OMT with at least two different methods within the CST Suite. I used the transient solver which is based on the FIT method and the TLM solver which is based on the TLM method.
I understand that each solver uses different meshing technique, but that should not have a significant effect on the scatttering parameters (which I am observing), should it?
I appreciate your responses.
in a continuous system, the pressure is 3 mbar. this pressure is produced by using an ejector at the end of the pipe line. in the middle of the process there is a tank which has liquid and vapor phases. I want to make sure that no liquid would enter the vacuum pipe. Is there any method to calculate the minimum height of the tank? the tank is a cylinder with the volume V.
One of the vent gas stream contains hydrochloric acid and we are planning to dispose of it by burning it in a flare. Could anyone help me understand whether it will burn and what is the reaction and what will be the components of product of combustion?
The photographic language offers additional, differential and inductive resources for the creation in the project process, beside the technical sketches, drawing, prototypes and others?
The area projetual prioritizes the functional, esthetic, emotional, symbolic and technological aspects between others, which has been taking the designers to investigate and to implement new techniques for the handling, constitution and interpretation of the images in the project stages.
Currently, my group members and I are in the process of designing and developing an actual V-blender machine that is of low cost to be used as industrial purpose. Thus, several parameters are to be looked upon this case. Generally, it will give effect in the after product.
The literature is not definitively clear about the use of mid-point categories on self-report Likert scales. For example, some say that mid-point choices increase scale reliability (Courtenay & Weidemann, 1985; Madden & Klopfer, 1978), while detractors claim that mid-pointing could result in satisficing, (Krosnick, Narayan, & Smith. 1996), which could cluster responses at the mid-point. I am in the process of designing a scale and would appreciate your thoughts on the matter.
Courtenay, B. C., & Weidemann, C. ( 1985). The effects of a don't know response on Palmore's facts on aging quizzes. The Gerontologist, 25, 177-181.
Krosnick, J. A., Narayan, S., & Smith, W. R. ( 1996). Sati sf icing in surveys: Initial evidence. In M. T. Braverman & J. K. Slater (Eds.), Ad1•ances in survey research (pp. 29-44). San Francisco: Sage.
Madden, T. M., & Klopfer. F. J. ( 1978). The "cannot decide" option in Thurstone-typc attitude scales. Educational and Psychological Measurement, 38, 259-264.
I am in the process of designing my post-graduate research study. I'm exploring the idea of assessing gait patterns which could then translate to better rehabilitation through more focused clinical assessment within the Maltese population.
I'm aware that there are several research studies which have been published on this subject however these are specific to certain populations, for example traumatic amputees, or vascular amputees, or bilateral amputees.
My aim is to assess unilateral TT amputees, however there is an enormous list of variables to omit or include, especially in the 60+ age bracket (which is the bulk of amputees in Malta). Most are Vascular patients who would usually also suffer from Diabetes.
I was thinking of analysing Spatio-Temporal parameters with 3D motion capture, and comparing it to a low cost accelerometer technology which is ideal for clinical set-ups.
Any feedback please?
I am currently in the process of designing evaluative frameworks for different services within a Children's Services department. I would be keen to see any existing evaluative frameworks or processes which could be adapted for use here. We are aiming to be able to generate a standard framework to be used across different services to evaluate their implementation, effectiveness and outcomes for children and families. If there are any key texts or existing evaluative frameworks I would be extremely grateful if you could let me know.
Thank you for the help!
I want to design some simulation-based scenarios involving students from different health care disciplines, and also assess the effectiveness of interprofessional simulation experience on student's learning.
Would you like to share some suggestions about the whole process (design, implementation, and assessment)?
We are in the process of designing and fabrication of apricot pit cracker for ladakh region of Jammu and Kashmir state.
I am following the thesis of Martin Land (very good work), but I can not find references that easily describe the ways to implement WLC. I'm trying to do some simulations with this system.
Regarding HSA (Heterogeneous System Architecture) foundation and all the prototypes and simulator, etc. that they are releasing ... I am especially interested in the global memory hierarchy ... How exactly are the CPU memory hierarchy and GPU memory hierarchy going to be integrated in HSA? This is still quite vague.
I'm in the process of designing a simple flow panel for human PBMCs and am looking for one marker that would best identify neutrophils. CD66b seems like a relatively new and specific marker, but I'm open to suggestions!
These days I am working to scale up a new process based on laboratory data. There are several chemicals which still have no adequate thermodynamic and transport property data. To measure all of the required data for engineering design will be very tedious and costly, thus, is it appropriate to just use the group contribution method as the thermodynamic and transport property data generator?
In the steam reforming of Naphtha (avg formula C11H24) I'm considering to add a pre-reformer to first reduce the heavy hydrocarbons to methane and then use a membrane reactor to convert the methane to hydrogen. Anyone with previous experience in this process? Is there a more "updated" catalyst than the Ferroxide / Thoriumdioxide combination ?
I personally see a process as a sequence of activities, so I go for the imperative paradigm. But in the last 5 years, I have come across a lot of work on declarative processes. I am still not convinced that declarative processes are intuitive. Can anyone please explain if I am wrong?
For collecting spilled paddy I want to design a cyclone separator. The blower will suck the paddy from ground into the cyclone separator.
I am looking for input to help the development of this thesis question and/or possible avenues of research.
Input may include specific architects that strictly use physical model making to inform their design decisions or literature that might review this design technique.
All comments and criticisms are welcome.
Engineers need a wide range of instruments for different mineral industries. The engineers must evaluate each application during the process design and select an appropriate instrument.
I am wondering how I can change the "trace" or >0.001 values in the stream table in Aspen Plus v8.0 to rational numbers, PPM or PPB. Furthermore, for the unit of enthalpy I always get Gcal/hr no matter what system of units I choose (e.g. SI, CGS) whereas I want it to be shown in GJ/hr.
Glycerine can be used as an environmentally friendly solvent in extractive distillation, however, due to its thermal decomposition at high temperatures, there might be some limitations for its applicability.
I would like to know how can I use the results from a steady-state simulation in PRO/II for dynamic simulation and what the easiest way to this is? I only know that there is an application called DynSim that might be useful.
When modeling ethylene/PE solubility, UNIFAC group parameters are required for each component of system. So I am a little bit confused about ethylene. Will it be from second group or first?
We have built an electric racing car and we are thinking of a business plan in a theoretical sense to increase production from 1 unit to 10 and then in an year make 1000 such cars.In 3 years the target is to make 3000 such cars.I would like to know the approach for that with respect to optimization of production processes and also costs.
I'm modeling reactor gas discharge concentration to a piece of scrubbing equipment. HCl concentrations vary from 22w% to 0w% while temperature varies from ambient to 110C. Does anyone know of equations to estimate vapor concentrations over the solution or of tabular data that I could build a look up table?
I want to design a cyclone separator for cleaning the product gases of a steam gasification process. The gases will exit the reactor at around 850degC.
I'm designing a device for the neutralization of a chlorpyrifos ethyl gas current via chemical absorption in a Sodium hydroxide solution. In order to decide what equipment to use (packed tower, bubble reactor, etc.), I need the liquid-phase mass transfer coefficient, be it provided by actual experimentation on this particular reaction or via correlations that could fit to this system.
The details are to include mass balance of what goes in, what happens within and the products from the reactor.