Publications related to Primates (10,000)
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Existen siete especies de monos araña, las cuales son los de vientre amarillo (Ateles belzebuth), de mano negra (A. geoffroyi), maquisapa (A. chamek), de cabeza negra (A. fusciceps), norteño (A. hybridus), cara blanca (A. marginatus) y negro (A. paniscus) pertenecientes al grupo de los primates que viven en la parte alta de los árboles de las selva...
Urbanization has transformed natural habitats by concentrating human populations in urban areas, with important consequences for biodiversity. In Colombia, several mammals, including primates, have occupied urban areas in different regions of the country. The objective of this study is to compile information on night monkeys (Aotus spp.) in urban a...
Tool use is taxonomically associated with high behavioural flexibility and innovativeness, and its prevalence is greater in primates and some bird species. This association, however, is not known to be causally determinant of tool-related competence since flexibility and innovativeness are often observed in the absence of tool use and vice versa. F...
Phylogenetic studies across a range of tetrapod groups have historically utilised either mitochondrial DNA, concatenated mito-nuclear matrices, or nuclear loci to infer divergence estimates. As such, the discordance between estimates inferred using differing data types has been a topic of interest over the past decade. Although several studies have...
Eliciting broadly neutralizing antibodies that protect against diverse HIV-1 strains is a primary goal of AIDS vaccine research. We characterized Ab1456 and Ab1271, two heterologously-neutralizing antibodies elicited in non-human primates by priming with an engineered V3-targeting SOSIP Env immunogen and boosting with increasingly native-like SOSIP...
Similarity or homophily in personality drives preferential strong social bonds or friendships in humans and some non-human primate species. However, little is known about the general behavioral “decision rules” underlying animal friendships in other taxa. We investigated a feral and free-ranging population of water buffalo (Bubalus bubalis) to dete...
In humans and nonhuman primates, the central 1° of vision is processed by the foveola, a retinal structure that comprises a high density of photoreceptors and is crucial for primate-specific high-acuity vision, color vision and gaze-directed visual attention. Here, we developed high-spatial-resolution ultrahigh-field 7T functional magnetic resonanc...
The human pulvinar is considered a prototypical associative thalamic nucleus as it represents a key node in several cortico‐subcortical networks. Through this extensive connectivity to widespread brain areas, it has been suggested that the pulvinar may play a central role in modulating cortical oscillatory dynamics of complex cognitive and executiv...
The accumulation of germline mutations underpins population diversity and drives genetic evolution. Despite the availability of extensive phylogenetic data, the lack of suitable methodologies has hindered the comprehensive characterization of germline mutational processes across evolutionary trees. To address this, we develop a robust three-step me...
How biological neural networks reliably process information in the presence of spontaneous activity remains controversial. In mouse primary visual cortex (V1), stimulus-evoked and spontaneous activity show orthogonal (dissimilar) patterns, which is advantageous for separating sensory signals from internal noise. However, studies in carnivore and pr...
The Three Pillars (Harmonization, Replacement, and Justice) describe an ethical path forward and away from the use of nonhuman primates in harmful research and scientific use. Conducting nonhuman primate research in an ethical way that acknowledges their moral importance requires satisfying more rigorous guidelines and regulations modeled on those...
Due to Andean bears' propensity for inhabiting challenging environments and terrain, their wild ecology remains poorly understood, especially when compared to other members of the Ursidae family. In one of the steepest, wettest regions of the Andes, the Kosñipata Valley of southeastern Peru, we attached and retrieved camera‐borne collars on three w...
Rhythm is an important component of human language and music production. Rhythms such as isochrony (intervals spaced equally in time) are also present in vocalizations of certain non-human species, including several birds and mammals. This study aimed to identify rhythmic patterns with music-based methods within the display behaviour of chimpanzees...
Fear of snakes is common not only in humans but also in other primates. Consequently, snakes are salient stimuli associated with prioritized attention, early detection and emotional significance. This has been interpreted as an adaptive evolutionary response of the primate brain to a risk of envenoming by a hidden snake. However, the struggle betwe...
Accurate eye tracking is crucial for gaze-dependent research, but calibrating eye trackers in subjects who cannot follow instructions, such as human infants and nonhuman primates, presents a challenge. Traditional calibration methods rely on verbal instructions, which are ineffective for these populations. To address this, researchers often use att...
Taenia martis cysticercosis is a rare but recently more frequently reported disease that can affect both human and non-human primates as aberrant hosts. A common marmoset was noticed as being affected by advancing weight loss that did not respond to therapy and finally had to be euthanized due to poor prognosis. A complete necropsy with gross evalu...
The extant colobine monkeys are a large primate radiation represented by two geographic subtribes, the African Colobina Blyth, 1875 and the Asian Presbytina Gray, 1825. The phylogenetic relationships of the colobinans are well resolved, but uncertainty persists among presbytinans. This study combines a large molecular dataset with a novel morpholog...
This is the copy of paper by T.H. Bullock on the evolution of brains available on Cogprints Web at address https://web-archive.southampton.ac.uk/cogprints.org/2581/index.html which led to the analysis of local field potentials coherence time variiability and was was proposed by the author to be used in a NIH Grant application in 1993 Grades in neur...
In many scientific fields, sparseness and indirectness of empirical evidence pose fundamental challenges to theory development. Theories of the evolution of human cognition provide a guiding example, where the targets of study are evolutionary processes that occurred in the ancestors of present-day humans. In many cases, the evidence is both very s...
Gunung Palung National Park (GPNP) and the surrounding region in West Kalimantan, Indonesia, host a significant population of Critically Endangered Bornean orangutans ( Pongo pygmaeus wurmbii ) amidst various conservation challenges, including habitat destruction, the illegal pet trade, and human-wildlife conflict. The Gunung Palung Orangutan Conse...
Some animals seek information to solve problems when they do not know the answer. Information-seeking behavior has become a key focus in studies of animal metacognition, providing insights into how animals monitor their own knowledge states. This behavior is thought to be a form of metacognitive control. Nevertheless, research on such metacognitive...
Our knowledge of the functional and taxonomic diversity of the fossil colobine fauna (Colobinae Jerdon, 1867) from the Lower Omo Valley is based only on craniodental remains. Here we describe postcranial specimens of fossil colobines from the Usno and Shungura Formations, and provide in-depth insights into their functional anatomy and taxonomy. Com...
The primate posterior parietal cortex (PPC) withholds a unified representation of the visual space supporting visual exploration, while the hippocampus (HPC) provides a memory-based cognitive place map of the environment. To probe the interactions between these two representations, i.e. between view and place, we compared neural activity in the two...
Because large brains are energetically expensive, they are associated with metabolic traits that facilitate energy availability across vertebrates. However, the biological underpinnings driving these traits are not known. Given its role in regulating host metabolism in disease studies, we hypothesized that the gut microbiome contributes to variatio...
V4, an intermediate visual area in the ventral visual stream of primates, is known to contain neurons tuned to color, complex local patterns, shape, and texture. Neurons with similar visual attribute preferences are closely positioned on the cortical surface, forming a topological map. Recent studies based on multi-electrode arrays and calcium imag...
Sacred forests are traditional management systems aimed at biodiversity conservation, yet few studies focus on the mammalian fauna of these ecosystems. This study aims to assess mammal diversity in the Gbétitapéa sacred forest to promote this endogenous conservation approach. Specifically, it seeks to identify the mammal species present in this for...
Hybridization and introgression are widespread in nature, with important implications for adaptation and speciation. Since heterogametic hybrids often have lower fitness than homogametic individuals, a phenomenon known as Haldane’s rule, loci inherited strictly through the heterogametic sex rarely introgress. We focus on the Y-chromosomal history o...
During infection, the fusion peptide (FP) of HIV envelope glycoprotein (Env) serves a central role in viral fusion with the host cell. As such, the FP is highly conserved and therefore an attractive epitope for vaccine design. Here, we describe a vaccination study in non-human primates (NHPs) where glycan deletions were made on soluble HIV Env to i...
Advances in three-dimensional culture technologies have facilitated the development of synthetic embryo models, such as blastoids, through the co-culturing of diverse stem cell types. These in vitro models enable precise investigation of developmental processes, including gastrulation, neurulation, and lineage specification, thereby advancing our u...
Knowledge about changes in wildlife populations over time is essential for making informed decisions regarding their conservation. We evaluated the influence of distinct habitat factors on the occupancy of Olalla's titi monkey (Plecturocebus olallae), a Critically Endangered primate endemic to Bolivia. We assessed the presence of titi monkey groups...
Recent advancements in long-read sequencing and assembly methods have ushered in an era of high-quality genome assemblies. Modern assemblies commonly feature megabase-long sequences frequently spanning entire chromosomes. The increase in the assembly contiguity and the reduced number of assembly contigs also implies that whole-genome alignment is n...
Background
The tree shrew (Tupaia belangeri) is a promising emerging model organism in biomedical studies, notably due to their evolutionary proximity to primates. To enhance our understanding of how DNA methylation is implicated in regulation of gene expression and the X chromosome inactivation (XCI) in tree shrew brains, here we present their fir...
Background
We have previously developed a DNA-based vaccine, INO-4500, encoding the Lassa lineage IV glycoprotein precursor. INO-4500, when delivered with electroporation, elicited humoral and cellular responses, and conferred 100% protection in cynomolgus non-human primates. Here, we expanded the characterization of INO-4500 assessing immunogenici...
The Zika virus (ZIKV) epidemic elicited a rapid commitment to the development of animal models for ZIKV research. Non-human primates (NHPs) and mice have made significant contributions to this research, but NHPs are expensive, have a long gestation period, and are available only in small numbers; non-genetically modified mice are resistant to infec...
Marburg virus (MARV) is a zoonotic virus that can infect humans and non-human primates (NHPs) and lead to a fatal Marburg hemorrhagic fever (MHF), while there is no approved vaccine or antiviral treatment for MHF. The nucleic acid vaccine has unique advantages, including fast and simple preparation, easy to follow the virus mutation situation, and...
The stage of offspring development at, and maternal physiology during, the peripartum and postpartum periods (comprising the last few days of gestation, parturition, and the first few days following birth) differ between rodents and primates. In both species, surfactants are produced by the fetal lungs in alveolar type II cells, forming conglomerat...
Daily, primates take a variety of decisions to establish why, when, and where to move. However, little is known about the factors influencing and shaping primate daily routes. We investigated the decision-making processes linked to route planning in four groups of black lion tamarins (BLT-Leontopithecus chrysopygus). We studied these endangered pla...
The face is the most important area on the human body for visually differentiating between individuals. When encountering another person, humans initially gaze at and perceive the face holistically, utilizing first-order relational information and specific neural systems. Information such as identity and emotional state are then obtained from the f...
Disadvantageous inequity aversion (IA), a negative response to receiving less than others, is a key building block of the human sense of fairness. While some theorize that IA is shared by species across the animal kingdom, others argue that it is an exclusively human evolutionary adaptation to the selective pressures of cooperation among non-kin. E...
The question of whether males or females are the more variable sex is long-standing, and yet to be fully answered. We investigate the relationships between body mass and variation across species using a phylogenetically informed analysis of the body mass of 337 species representing six mammalian orders. Within each order, we found that the larger s...
Nonhuman primates (NHPs) are pivotal for unlocking the complexities of human cognition, yet traditional cognitive studies remain constrained to specialized laboratories. To revolutionize this paradigm, we present CalliCog : an open-source, scalable in-cage platform tailored for freely behaving experiments in small primate species such as the common...
Humans, like many other primates, possess the ability to adopt, and the practice of child adoption exists across human societies. It is well-known that there are three distinct categories of child adoption—kin adoption (i.e., when a relative adopts a child), intrafamilial adoption (i.e., when a stepparent adopts a child) and stranger adoption (i.e....
The Facial Action Coding System (FACS) is an anatomically based system to study facial expression in humans. Currently, it is recognized that nonhuman animals, particularly nonhuman primates, have an extensive facial ethogram that changes according to the context and affective state. The facial expression of great apes, the closest species to human...
Las demandas judiciales en torno a los grandes simios hacen foco en un tema abordado desde la ética y el derecho animal: la consideración de los animales como sujetos de derecho. A partir de los procesos judiciales que involucraron a la orangutana Sandra y la chimpancé Cecilia, que estuvieron confinadas en zoológicos de Argentina, analizaremos los...
Over the course of human history, people have translocated plant and animal species, often with profound consequences. Understanding how endangered species adapt to human-mediated migration and novel environments is crucial to inform conservation strategies. The crested macaque (Macaca nigra), an endemic primate species of North Sulawesi (Indonesia...
Golden snub-nosed monkeys (Rhinopithecus roxellana) live in multilevel societies of over 100 individuals. Despite exploiting low visibility high-altitude forests and home ranges of 14 km², they maintain large and cohesive social networks that serve to coordinate travel and daily activities effectively. During traveling, foraging, and feeding, golde...
Nomascus leucogenys is a critically endangered species of small apes. Here, we sequenced and assembled the male genome of N. leucogenys, using PacBio and Hi-C datasets, with a particular focus on its Y-chromosome. The resulting high-quality haplotype-phased assemblies are at chromosome-scale, with scaffold/contig N50 values of 124.2/102.2 Mb for Ha...
Spiking neural networks (SNNs) have gained significant momentum in recent times as they transmit information via discrete spikes, similar to neuromorphic low-power systems. However, existing spike coding methods are often limited to a single scale of time or rate, and typically suffer from drawbacks such as reduced accuracy or long classification l...
We know vanishingly little about how long-lived apes experience senescence in the wild, particularly with respect to their foraging behaviors, which are essential for survival. Some wild apes use tools during foraging and, given the additional cognitive and physical challenges presented by tool use, we predict that such behaviors are at a heightene...
The genus Entamoeba infects both humans and NHPs. In zoos, visitors feeding significantly increases the frequency of human-to-NHP contact, thereby raising the risk of zoonotic transmission. In this study, six Entamoeba species were investigated and analyzed in the fecal samples of 14 NHP species from zoos in Beijing, Guiyang, Shijiazhuang, Tangshan...
In the last years, science started to move toward a more glio-neurocentric view, in which astrocytes are hypothesized to be directly involved in cognitive functions. Indeed, astrocytes show a variety of shapes with species-specific characteristics, suggesting a specialization of roles during evolution. Interlaminar (ILA) and varicose-projection (VP...
Saponin-based vaccine adjuvants are potent in preclinical animal models and humans, but their mechanisms of action remain poorly understood. Here, using a stabilized HIV envelope trimer immunogen, we carried out studies in non-human primates (NHPs) comparing the most common clinical adjuvant alum with Saponin/MPLA Nanoparticles (SMNP), a novel ISCO...
Large- and medium-sized mammals (LMMs) are closely related to humans and perform critical functions in the ecosystem. China harbors one of the richest mammalian faunas in the world, whereas there is an urgent need among wildlife managers and researchers to update the inventory of China’s LMM species based on recent empirical information. In this st...
Primates, the most colorful mammalian radiation, have previously served as an interesting model to test the functions and evolutionary drivers of variation in eye color. We assess the contribution of photo-regulatory and communicative functions to the external eye appearance of nine macaque species representing all the branches of their radiation....
Genetic variations in MS4A4A and MS4A6A are linked to the regulation of cerebrospinal fluid soluble TREM2 (sTREM2) levels and are associated with Alzheimer's disease (AD) risk and progression. Using CRISPR knockout and MS4A4A-degrading antibodies in primary human microglia, non-human primates (NHP), and a xenotransplantation model of amyloid pathol...
Intelligent behavior involves mentally arranging learned information in novel ways and is particularly well developed in humans. While nonhuman primates (NHP) will learn to arrange new items in complex serial order and re-arrange neighboring items within that order, it has remained contentious whether they are capable to re-assign items more flexib...
What are the fundamental units of representation in the primate visual brain? While objects have become an intuitive framework for studying neurons in many parts of cortex, it is possible that neurons follow a more expressive organizational principle, such as encoding generic features present across textures, places, and objects. In this study, we...
The term Homo sapiens is the scientific nomenclature for the anatomically modern man. This term
literally means "thinking man". Modern humans are found all over the world in different regions, and
are probably the most successful species in modern times, just like the dinosaurs were some one
hundred million years ago. Homo Sapiens are the most c...
With the recent rise in cases of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b infection in humans and animals, there is an associated increase in the risk of human-to-human transmission. In this study, we characterize recombinant A(H5N1) A/American Wigeon/South Carolina/22/000345-001/2021 (A/AW/SC/2021) clade 2.3.4.4b vaccine. Pu...
Transplantation of ex vivo engineered hematopoietic stem cells (HSCs) can lead to robust clinical responses but carries risks of adverse events from bone marrow mobilization, chemotherapy conditioning and other factors. HSCs have been modified in vivo using lipid nanoparticles (LNPs) decorated with targeting moieties, which increases manufacturing...
The growing view that consciousness is widespread, multimodal, and evolutionarily non-linear in complexity across the animal kingdom has given rise recently to a variety of strategies for representing the heterogeneous nature of animal phenomenology. While based on markers clearly associated with consciousness in humans, most of these strategies ar...
Have you ever wondered what skills you need to make friends?
How your brain processes the information that you need to make
friends? What features of your daily life make having friends difficult? Primates are the mammals that are most similar to us in the animal kingdom. Primates face similar challenges to humans when it comes to making friends. P...
Rare B cells can have special pathogen-recognition features giving them the potential to make outsized contributions to protective immunity. However, rare naive B cells infrequently participate in immune responses. We investigated how germline-targeting vaccine antigen delivery and adjuvant selection affect priming of exceptionally rare BG18-like H...
Mixed-species groups have been recorded in various primates, including tufted capuchin and squirrel monkeys. Measures of their ‘groupness’ are typically based on factors such as group stability, social interactions, proximity, or behavioural coordination. Social network analysis has become a useful tool for quantifying relationships among group-liv...
Modern empirical work confirms Darwin’s suggestion that some human expressions have precursors in non-human primates (Schirmer, et al. 2013). Non-human animals’ ability to recognize human emotions and intentions through their expressions, gestures and signals, has been confirmed by recent research data (Hare, et al. 2002; Kaminski, et al. 2004; Kam...
